CA2700263A1 - Soluble dosage forms containing cephem derivatives suitable for parenteral administration - Google Patents
Soluble dosage forms containing cephem derivatives suitable for parenteral administration Download PDFInfo
- Publication number
- CA2700263A1 CA2700263A1 CA2700263A CA2700263A CA2700263A1 CA 2700263 A1 CA2700263 A1 CA 2700263A1 CA 2700263 A CA2700263 A CA 2700263A CA 2700263 A CA2700263 A CA 2700263A CA 2700263 A1 CA2700263 A1 CA 2700263A1
- Authority
- CA
- Canada
- Prior art keywords
- dosage form
- ceftaroline
- mean
- acid
- fosamil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 238000007911 parenteral administration Methods 0.000 title claims abstract description 25
- 150000001782 cephems Chemical class 0.000 title description 2
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97419407P | 2007-09-21 | 2007-09-21 | |
| US60/974,194 | 2007-09-21 | ||
| PCT/US2008/076920 WO2009039324A1 (en) | 2007-09-21 | 2008-09-19 | Soluble dosage forms containing cephem derivatives suitable for parenteral administration |
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| CA2700263A Abandoned CA2700263A1 (en) | 2007-09-21 | 2008-09-19 | Soluble dosage forms containing cephem derivatives suitable for parenteral administration |
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| EP (2) | EP2200618A4 (enExample) |
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| MX (1) | MX2010003112A (enExample) |
| RU (1) | RU2537237C2 (enExample) |
| WO (1) | WO2009039324A1 (enExample) |
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| PH12012500528A1 (en) * | 2009-09-21 | 2019-06-14 | Astrazeneca Ab | Compositions and methods for treating bacterial infections using caftaroline |
| AR088372A1 (es) * | 2011-10-19 | 2014-05-28 | Otsuka Pharma Co Ltd | Solucion para administracion oral |
| WO2016008393A1 (zh) * | 2014-07-14 | 2016-01-21 | 正大天晴药业集团股份有限公司 | 头孢罗膦氨基酸盐及其结晶 |
| CN104258403B (zh) * | 2014-09-28 | 2017-03-01 | 刘宗侠 | 一种西洛他唑组合物及其制备方法 |
| KR20170038214A (ko) * | 2015-09-30 | 2017-04-07 | (주)아모레퍼시픽 | 당산 및 플라보노이드를 포함하는 항균용 조성물 |
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| US4028355A (en) * | 1974-01-23 | 1977-06-07 | Smithkline Corporation | Cephalosporin purification process |
| GB8729574D0 (en) * | 1987-12-18 | 1988-02-03 | Fujisawa Pharmaceutical Co | Water-soluble antibiotic composition |
| JPH02124822A (ja) * | 1988-11-02 | 1990-05-14 | Eisai Co Ltd | セファロスポリン含有注射用組成物 |
| JP2761005B2 (ja) * | 1988-11-02 | 1998-06-04 | エーザイ株式会社 | セファロスポリン含有注射用組成物 |
| EP0395219B1 (en) * | 1989-03-30 | 1998-09-30 | Pfizer Inc. | Cephalosporins and their homologues, process for their preparation and pharmaceutical compositions |
| DE69004921T2 (de) * | 1989-09-30 | 1994-05-05 | Eisai Co Ltd | Injizierbare Cephalosporinpräparate und ihre Anwendung. |
| JPH0840907A (ja) * | 1994-08-03 | 1996-02-13 | Meiji Seika Kaisha Ltd | セファロスポリン注射剤 |
| TW473479B (en) | 1997-12-19 | 2002-01-21 | Takeda Chemical Industries Ltd | Phosphonocephem derivatives, their production and use |
| US7527807B2 (en) * | 2000-06-21 | 2009-05-05 | Cubist Pharmaceuticals, Inc. | Compositions and methods for increasing the oral absorption of antimicrobials |
| EP2020416A1 (en) * | 2000-08-10 | 2009-02-04 | Takeda Pharmaceutical Company Limited | Phosphonocephem compound |
| JP3586226B2 (ja) * | 2000-08-10 | 2004-11-10 | 武田薬品工業株式会社 | ホスホノセフェム化合物 |
| WO2004096279A1 (ja) * | 2003-04-28 | 2004-11-11 | Takeda Pharmaceutical Company Limited | 注射用組成物 |
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2008
- 2008-09-19 AU AU2008302201A patent/AU2008302201A1/en not_active Abandoned
- 2008-09-19 US US12/233,662 patent/US20090082326A1/en not_active Abandoned
- 2008-09-19 EP EP20080832124 patent/EP2200618A4/en not_active Withdrawn
- 2008-09-19 CN CN201410162742.4A patent/CN103919720A/zh active Pending
- 2008-09-19 RU RU2010115268/15A patent/RU2537237C2/ru not_active Application Discontinuation
- 2008-09-19 KR KR1020107008731A patent/KR101599560B1/ko not_active Expired - Fee Related
- 2008-09-19 CN CN2012104792814A patent/CN102935065A/zh active Pending
- 2008-09-19 WO PCT/US2008/076920 patent/WO2009039324A1/en not_active Ceased
- 2008-09-19 EP EP15166135.2A patent/EP2952195A1/en not_active Withdrawn
- 2008-09-19 CA CA2700263A patent/CA2700263A1/en not_active Abandoned
- 2008-09-19 CN CN200880117449A patent/CN101868240A/zh active Pending
- 2008-09-19 BR BRPI0816412A patent/BRPI0816412A2/pt not_active IP Right Cessation
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- 2008-09-19 JP JP2010525983A patent/JP2010540448A/ja active Pending
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2011
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2015
- 2015-03-04 US US14/638,449 patent/US20150196572A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008302201A1 (en) | 2009-03-26 |
| JP2010540448A (ja) | 2010-12-24 |
| CN102935065A (zh) | 2013-02-20 |
| MX2010003112A (es) | 2010-08-11 |
| RU2010115268A (ru) | 2011-10-27 |
| BRPI0816412A2 (pt) | 2017-05-16 |
| WO2009039324A1 (en) | 2009-03-26 |
| KR101599560B1 (ko) | 2016-03-03 |
| EP2200618A4 (en) | 2010-11-03 |
| KR20100075942A (ko) | 2010-07-05 |
| US20090082326A1 (en) | 2009-03-26 |
| CN101868240A (zh) | 2010-10-20 |
| US20150196572A1 (en) | 2015-07-16 |
| EP2200618A1 (en) | 2010-06-30 |
| RU2537237C2 (ru) | 2014-12-27 |
| EP2952195A1 (en) | 2015-12-09 |
| US20120010180A1 (en) | 2012-01-12 |
| CN103919720A (zh) | 2014-07-16 |
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