KR101580962B1 - Cosmetic composition for cellulite reduction comprising fermented rice bran extract and bitter orange extract - Google Patents

Cosmetic composition for cellulite reduction comprising fermented rice bran extract and bitter orange extract Download PDF

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Publication number
KR101580962B1
KR101580962B1 KR1020150159402A KR20150159402A KR101580962B1 KR 101580962 B1 KR101580962 B1 KR 101580962B1 KR 1020150159402 A KR1020150159402 A KR 1020150159402A KR 20150159402 A KR20150159402 A KR 20150159402A KR 101580962 B1 KR101580962 B1 KR 101580962B1
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KR
South Korea
Prior art keywords
extract
cosmetic composition
rice bran
cellulite
fermented
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KR1020150159402A
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Korean (ko)
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임승호
나성원
오경희
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(주)한솔바이오텍
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

Abstract

The present invention relates to a cosmetic composition for reducing cellulite, containing a fermented rice bran extract and a bitter orange extract, and more specifically, to a cosmetic composition for reducing cellulite, containing a fermented rice bran extract and a bitter orange extract, wherein the extracts show strong synergetic effects in terms of cellulite reduction. According to the present invention, the cosmetic composition, containing the rice bran extract fermented by microorganisms and the bitter orange extract as the active ingredients, has very strong synergetic effects in terms of cellulite reduction due to the extracts of the present invention, thereby effectively reducing cellulite.

Description

TECHNICAL FIELD The present invention relates to a cosmetic composition for reducing cellulite comprising a fermented rice bran extract and a beet orange extract.

The present invention relates to a cosmetic composition for reducing cellulite comprising fermented rice bran extract and Beater orange extract, which comprises a fermented rice bran extract having a strong synergistic effect with respect to cellulite reducing effect and a beater orange extract, To a cosmetic composition.

Normal fat cells receive proper nutrients from blood vessels and store them and metabolize themselves to release waste products. However, when the supply is much higher than that of energy, they are stored as fat in the fat cells, and when the energy is insufficient, And glucose. Obesity is attributed to the accumulation of excessive triglyceride in fat cells due to the imbalance of this process and the increase in the number of fat cells.

One of the problems deriving from obesity is cellulite. Cellulite is a cellulite formed by the strands of skin fibroblasts connecting the tissue layers of the skin and the deep to form a compartment containing cells containing the fat and the cells containing the fat are enlarged and consequently the compartment becomes larger and the skin becomes rugged to be. Cellulite occurs particularly frequently in women. In the area where the cellulite is accumulated, the lymphatic fluid is stagnated due to the abnormality of the lymphatic system, so that a kind of swelling occurs at the site, and the body may appear to be more steamed. Cellulite is not only a cosmetic problem, but also accumulates toxic substances in the body due to the stagnation of lymphatic fluid, which can damage skin cells and inhibit nutrient intake, leading to skin aging and cell necrosis.

Fat is easily removed through diet or exercise, but there is an increasing demand for cellulite removal only for cellulite removal because cellulite is not easy to remove. The prior art discloses caffeine as a lipid degradation or cellulite reducing substance as disclosed in Korean Laid-Open Patent Application No. 2015-0072797, and caffeine is known to be a toxic substance, and side effects such as bronchodilation and deterioration of the premenstrual syndrome phenomenon have been reported.

Therefore, it is necessary to find a combination of a natural material having a cellulite reducing effect and no side effects, or a natural material having a synergistic effect against a cellulite reducing effect.

Korea Patent Publication No. 2015-0072797

In order to solve the problems of the prior art as described above,

The present inventors have found that a fermented extract of rice gum and a beater orange extract exhibit a very strong synergistic effect while seeking a combination of natural extracts exhibiting a synergistic effect on cellulite reduction or lipolytic effect.

Accordingly, it is an object of the present invention to provide a cosmetic composition for cellulite reduction comprising an extract of fermented rice bran and Citrus aurantium L. extract as an active ingredient.

In order to accomplish the object of the present invention, the present invention provides a cosmetic composition for reducing cellulite comprising an extract from rice germ extract and citrus aurantium L. extract as an active ingredient.

The above fermented rice bran extract may contain at least one selected from the group consisting of Lactobacillus sp., Rhizobium sp., Saccharomyces sp. And Acetobacter sp. Which is a microorganism-containing fermented microorganism.

The mixture weight ratio of the rice germinated fermented extract and the bitter orange extract may be 1: 0.1 to 10.

The cosmetic composition may further comprise a skin absorption promoting agent.

Wherein the skin absorption promoter is at least one compound selected from the group consisting of pyrrolidone derivatives, propylene glycol, isopropyl myristate, crotamiton, polysorbate 80, peppermint oil, alpha limonene, oleic acid, lauric acid, lanolin and glycerin And preferably glycerin.

The cosmetic composition according to the present invention may contain a mixture of a fermented rice gruel extract and a bitter orange extract and a water absorption promoter at a weight ratio of 1: 0.1 to 10.

The cosmetic composition according to the present invention may further have a lipolysis effect.

The extraction solvent used for preparing the rice bran extract or the beater orange extract may be at least one selected from the group consisting of water, methanol, ethanol, ethyl acetate, isopropanol, butanol, acetone and ethyl methyl ketone.

The cosmetic composition according to the present invention comprising the extract of rice bran fermented with microorganism and the extract of Beater orange as an effective ingredient has a strong synergistic effect on the cellulite reducing effect of the two extracts, have.

The present invention provides a cosmetic composition for cellulite reduction comprising an extract of fermented rice bran and Citrus aurantium L. extract as an active ingredient.

The fermented rice bran extract and Beater orange extract contained in the cosmetic composition according to the present invention show a very large synergistic effect on the cellulite reducing effect.

Rice cores are made of rice husks and rice husks made of rice husks and rice husks, which are produced in the process of rice baking to white rice. Analysis of the nutrient content of rice reveals that 29% of rice bran, 66% of rice bran, and 5% 95% of the nutrients of rice are in the rice mead, which consists of rice bran and rice husk (Juliano BO. 1985. Rice bran. In Rice: Chemistry and technology 2nd ed. Julian BO, ed. American Association of Cereal Chemist, Inc , St. Paul MN p647).

The fermented extract of rice gangue is a fermented product of microbial fermentation of rice bran, which can accelerate the absorption into the living body by decomposing physiologically active substances contained in rice gangue into small molecules through microbial fermentation. The microorganism may be any safe fermenting microorganism that can be used for cosmetics or food production, and includes, but is not limited to, Lactobacillus sp., Rhizobium sp., Saccharomyces sp. Saccharomyces sp.) And Acetobacter sp., And preferably Rhizobium sp. Microorganisms or Rhizobium radiobacter . The microorganism may be selected from the group consisting of Rhizobium sp. And may further comprise at least one microorganism selected from the group consisting of Lactobacillus sp., Saccharomyces sp., And Acetobacter sp.

Citrus aurantium L., also known as citrus fruit, is an evergreen broad-leaved bush, planted in fruit juice in Jeju Island, native to Southeast Asia. It grows up to 7m in height and has a thorn on the stem. Leaves are alternate phyllotaxis, oval, 7-10cm long, pointed gradually, with sawtooth on edge, many oil dots, broad wings on petiole. The flowers bloom in May and have fragrance and one or a few on the axilla. Fruits are berry, round, ripened in October with yellowish red.

The extract of Beater orange according to the present invention may be extracted from one or more parts selected from the group consisting of flowers, branches, stems, leaves, fruits and roots of Bitter orange, preferably flowers.

The mixture weight ratio of the rice germinated fermented extract and the bitter orange extract is not limited thereto but may be 1: 0.1-10, 1: 0.5-10, 1: 0.5-5, 1: 1-5, 1: 1-3, 1: 1.5 ~ 2.5 or 1: 1.5 ~ 2.

The cosmetic composition according to the present invention may further comprise a skin absorption promoting agent so that the fermented rice extract and the bitter orange extract can be well absorbed to the skin, and the skin absorption promoting agent may be a common ingredient used in the cosmetics or medicine industry have. In addition, the skin absorption promoting agent may be specifically selected from the group consisting of pyrrolidone derivatives, propylene glycol, isopropyl myristate, crotamiton, polysorbate 80, mint oil, alpha limonene, oleic acid, lauric acid, lanolin and glycerin May be one or more components selected, preferably glycerin, lanolin, or mixtures thereof, more preferably glycerin.

The cosmetic composition according to the present invention is not limited to the mixed extract of the fermented rice gruel extract and the beater orange extract and the skin absorption promoter but may be used at a ratio of 1: 0.1-10, 1: 0.1-9, 1: 0.1-8, 1: 0.1 to 6, 1: 0.1 to 5, 1: 0.1 to 4, 1: 0.1 to 3, 1: 0.1 to 2, or 1: 0.1 to 1.

Since the fermented rice extract and the beater orange extract exhibit a strong synergistic effect on the lipolytic effect, the cosmetic composition according to the present invention not only has a cellulite reducing effect, but also has an excellent lipolytic effect.

The extraction solvent used in the preparation of the fermented rice gruel extract or the beater orange extract according to the present invention is not limited thereto but may be one or more selected from the group consisting of water, methanol, ethanol, ethyl acetate, isopropanol, butanol, acetone and ethyl methyl ketone And preferably ethanol.

In addition, the cosmetic composition according to the present invention can be prepared into a liquid or solid form using a base, an adjuvant or an additive commonly used in the field of cosmetics. Liquid or solid form of cosmetics may include, for example, but not limited to, lotions, creams, lotions, or bath salts. At this time, the bases, adjuvants and additives commonly used in the cosmetics field are not particularly limited and may include, for example, water, alcohol, propylene glycol, stearic acid, glycerol, cetyl alcohol or liquid paraffin.

More specifically, the cosmetic composition of the present invention contains a fermented extract of rice ghass and an extract of Beeta orange as an active ingredient, together with dermatologically acceptable excipients, a basic cosmetic composition (such as a lotion such as lotion, cream, essence, cleansing foam and cleansing water, , Body oil), functional cosmetic composition (lipstick blocker, wrinkle remover) or soap. Such excipients include, but are not limited to, for example, emollients, skin penetration enhancers, colorants, fragrances, emulsifiers, thickeners or solvents. In addition, it may further contain a perfume, a coloring agent, a bactericide, an antioxidant, an antiseptic or a moisturizing agent, and may contain an enhancer, an inorganic salt, a synthetic polymer material and the like for the purpose of improving physical properties.

For example, when a detergent or soap containing the fermented rice bran extract and the beater orange extract of the present invention is prepared, it can be easily prepared by adding the fermented rice bran extract and the beater orange extract to a common cleanser or soap base. In the case of producing a cream, it can be prepared by adding a fermented rice gruel extract and a bitter orange extract to a general underwater type (O / W) cream base. A synthetic or natural material such as a flavor, a chelating agent, a coloring matter, an antioxidant, an antiseptic, and a protein, a mineral, and a vitamin for the purpose of improving a physical property may be further added.

The total content of the fermented rice gangue extract and the bitter orange extract contained in the cosmetic composition of the present invention may be 0.0001 to 50% by weight based on the total weight of the cosmetic composition.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood that the scope of the present invention is not limited by these examples in accordance with the gist of the present invention, and it is to be understood by those skilled in the art that the present invention is not limited thereto It will be obvious.

≪ Preparation of Examples and Comparative Examples >

1. Preparation of rice bran extract and its fermentation product

Rice bran (Seoul tilting Market, Korea) was treated for separation tank emptying radio bakteo (Rhizobium radiobacter, ATCC 31750) to 1kg as 1.0 × 10 10 CFU were fermented at 37 ℃ for 48 hours.

Then, 10% (v / w) of 70% ethanol was added to the fermented rice bran and the mixture was extracted at 50 ° C for 24 hours. The supernatant and the precipitate produced in the extraction process were separated and the supernatant was kept separately. The precipitate was subjected to ethanol extraction repeatedly as described above to obtain a second supernatant, which was then mixed with the supernatant. The mixed supernatant was centrifuged, filtered, concentrated and lyophilized to obtain a final 45 g powder sample.

2. Preparation of Beater Orange Extract

(V / w) of 70% ethanol was added to 1 kg of beater orange flowers and extracted at 50% for 24 hours. The supernatant and the precipitate produced by the extraction were separated and the supernatant was separately stored. The precipitate was subjected to ethanol extraction repeatedly as described above to obtain a second supernatant, which was then mixed with the supernatant. The mixed supernatant was centrifuged, filtered, concentrated, and lyophilized to obtain a final powder sample.

3. Setting of Examples and Comparative Examples

The prepared samples were mixed as shown in Table 1 below to prepare a cosmetic sample. The following glycerin and lanolin serve as skin absorption promoters.

The constitutions (unit: wt%) of Examples and Comparative Examples ingredient Comparative Example Example One 2 One 2 3 4 5 6 Rice bran fermented extract 40 - 5 10 15 20 25 15 Bitter orange extract - 40 35 30 25 20 15 25 glycerin 30 30 30 30 30 30 30 - lanolin - - - - - - - 30 Excipient 30 30 30 30 30 30 30 30

≪ Preparation of Formulation Example &

Formulation Examples 1 to 8 were prepared by preparing a cream cosmetic composition having the composition shown in the following Table 3, which contained the above Examples 1 to 6 and Comparative Examples 1 and 2, respectively, as shown in Table 2 below.

Inclusion component of formulation example Formulation Example One 2 3 4 5 6 7 8 Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Comparative Example 1 Comparative Example 2

Composition ratio (unit:% by weight) ingredient The composition ratio constituting the formulation example Purified water 18.5 Incrementer 0.5 Moisturizer 10 Example 40 Emulsifying stabilizer 10 vegetable oil 10 Beads wax 5 Silicone oil 5 incense One

<Experimental Example - Anti-cellulite effect test>

Eighty women aged 25-35 were recruited to the subjects, and then Formulation Examples 1 to 8 were each divided into 10 subjects, and the thighs were applied twice a day for a sufficient amount for 12 weeks. However, the subjects were managed to maintain a regular life and a certain diet during the test period.

After 12 weeks, the anti-cellulite effect was evaluated on the subjects as follows.

Experimental Example 1: Measurement of thigh circumference

The thigh circumference was measured using a tape measure (unit: mm). Using the measured thigh circumference (L 0 ) and the measured thigh circumference (L 1 ) before the start of the test, the average value (rounded off at the second decimal place) of the subject's reduced thighs was calculated for each formulation, The values are shown in Table 4 below.

Thigh circumference reduction (unit: cm) Formulation Example One 2 3 4 5 6 7 8 Reduced thigh circumference 0.4 0.8 1.2 1.0 0.5 0.8 0.3 0.2

From the above results, it can be seen that the results of Formulation Examples 1 to 5 are superior to those of Formulation Examples 7 and 8, and thus the fermented extract of rice gum and the beater orange extract have a synergistic effect in reducing thigh circumference. In addition, in Formulation Examples 2 to 4, about 2 times or more of the effect was generated as compared with Formulation Example 7 or 8, and thus it was possible to obtain a remarkably excellent synergistic effect by controlling the mixing ratio of the fermented rice bran extract and the beater orange extract Able to know.

It can also be seen that Formulation Example 3 and Formulation 6 are significantly superior to Formulation Example 6 in the effect of Formulation Example 3, despite the fact that both the crude fermented extract and the bitter orange extract were mixed at the same ratio. As a result, it can be seen that glycerin is more suitable as an excipient for accelerating skin absorption of corn steep liquor extract and beet orange extract than lanolin.

Experimental Example 2: Measurement of subcutaneous fat layer and cellulite thickness

The thickness of the subcutaneous fat layer and cellulite was measured using Ultrasound-EuB 415 US scanner. Using the measured values before and after the test, the numerical reduction rate of the subjects was calculated for each formulation, and the average value (rounded to two decimal places) is shown in Table 5 below.

Thickness reduction rate of subcutaneous fat layer and cellulite (unit:%) Formulation Example One 2 3 4 5 6 7 8 Subcutaneous fat layer reduction rate 1.3 2.4 3.4 2.7 1.6 2.6 0.5 0.3 Cellulite reduction rate 12.9 20.8 28.7 22.3 15.4 23.0 6 4

From the above results, it can be seen that the results of Formulation Examples 1 to 5 are superior to those of Formulation Examples 7 and 8, and thus the fermented extract of rice gum and the beater orange extract have a synergistic effect on reduction of subcutaneous fat and cellulite reduction have. In addition, in Formulation Examples 2 to 4, about 3 times or more of the effect was generated as compared with Formulation Example 7 or 8, and thus it was possible to obtain a remarkably excellent synergistic effect by controlling the mixing ratio of the fermented rice extract and the beater orange extract Able to know.

It can also be seen that Formulation Example 3 and Formulation 6 are significantly superior to Formulation Example 6 in the effect of Formulation Example 3, despite the fact that both the crude fermented extract and the bitter orange extract were mixed at the same ratio. As a result, it can be seen that glycerin is more suitable as an excipient for accelerating skin absorption of corn steep liquor extract and beet orange extract than lanolin.

Claims (9)

The present invention relates to a cosmetic composition for reducing cellulite comprising an extract of rice bran fermentation and an extract of Citrus aurantium L. as an active ingredient.
The method according to claim 1,
The above fermented rice bran extract may contain at least one selected from the group consisting of Lactobacillus sp., Rhizobium sp., Saccharomyces sp. And Acetobacter sp. Wherein the microcrystalline cellulose is an extract of rice bran fermented with a microorganism containing the microcrystalline cellulose.
The method according to claim 1,
The cosmetic composition for cellulite reduction according to claim 1, wherein the mixed weight ratio of the fermented rice bran extract and the bitter orange extract is 1: 0.1-10.
The method according to claim 1,
Wherein the cosmetic composition further comprises a skin absorption promoting agent.
5. The method of claim 4,
Wherein the skin absorption promoting agent is at least one selected from the group consisting of pyrrolidone derivatives, propylene glycol, isopropyl myristate, crotamiton, polysorbate 80, peppermint oil, alpha limonene, oleic acid, lauric acid, lanolin and glycerin &Lt; / RTI &gt; the cosmetic composition for cellulite reduction.
6. The method of claim 5,
The cosmetic composition for cellulite reduction according to claim 1, wherein the skin absorption promoter is glycerin.
5. The method of claim 4,
Wherein the cosmetic composition comprises a mixture of a fermented rice bran extract and a bitter orange extract and a water absorption promoter at a weight ratio of 1: 0.1 to 10.
The method according to claim 1,
The cosmetic composition for cellulite reduction according to claim 1, wherein the cosmetic composition further has a lipolytic effect.
The method according to claim 1,
The extraction solvent used for preparing the fermented rice bran extract or the beater orange extract is at least one selected from the group consisting of water, methanol, ethanol, ethyl acetate, isopropanol, butanol, acetone and ethyl methyl ketone. Cosmetic composition.
KR1020150159402A 2015-11-13 2015-11-13 Cosmetic composition for cellulite reduction comprising fermented rice bran extract and bitter orange extract KR101580962B1 (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107625670A (en) * 2016-07-19 2018-01-26 黄秉炘 Thermal water and crops fermentation skin care products processing procedure
KR20190059122A (en) * 2017-11-22 2019-05-30 권흥원 Manufacturing method of Aqueous Colloidal Dispersion for cosmetic material from synthetic diamond
KR102411229B1 (en) 2021-12-23 2022-06-22 주식회사 네오캠코리아 Cosmetic composition for skin soothing and moisturizing improvement containing resurrection plant and bitter orange flower complex extract

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110158922A1 (en) * 2008-04-15 2011-06-30 Immanence Integrale Dermo Correction Inc. Skin Care Compositions and Method of Use Thereof
KR20150072797A (en) 2013-12-20 2015-06-30 (주)아모레퍼시픽 Composition comprising high concentration caffeines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110158922A1 (en) * 2008-04-15 2011-06-30 Immanence Integrale Dermo Correction Inc. Skin Care Compositions and Method of Use Thereof
KR20150072797A (en) 2013-12-20 2015-06-30 (주)아모레퍼시픽 Composition comprising high concentration caffeines

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107625670A (en) * 2016-07-19 2018-01-26 黄秉炘 Thermal water and crops fermentation skin care products processing procedure
KR20190059122A (en) * 2017-11-22 2019-05-30 권흥원 Manufacturing method of Aqueous Colloidal Dispersion for cosmetic material from synthetic diamond
KR102060014B1 (en) 2017-11-22 2019-12-27 권흥원 Manufacturing method of Aqueous Colloidal Dispersion for cosmetic material from synthetic diamond
KR102411229B1 (en) 2021-12-23 2022-06-22 주식회사 네오캠코리아 Cosmetic composition for skin soothing and moisturizing improvement containing resurrection plant and bitter orange flower complex extract

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