KR101352806B1 - 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법 - Google Patents

결핵균 감염을 예방 또는 치료하기 위한 신규한 방법 Download PDF

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KR101352806B1
KR101352806B1 KR1020077027885A KR20077027885A KR101352806B1 KR 101352806 B1 KR101352806 B1 KR 101352806B1 KR 1020077027885 A KR1020077027885 A KR 1020077027885A KR 20077027885 A KR20077027885 A KR 20077027885A KR 101352806 B1 KR101352806 B1 KR 101352806B1
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pharmaceutical composition
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mtb72f
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KR20080021624A (ko
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레아 콜러
이베스 로베트
스티븐 리드
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인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이)
글락소스미스클라인 바이오로지칼즈 에스.에이.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1020077027885A 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법 Expired - Fee Related KR101352806B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US67654905P 2005-04-29 2005-04-29
US60/676,549 2005-04-29
US77701706P 2006-02-27 2006-02-27
US60/777,017 2006-02-27
PCT/EP2006/004319 WO2006117240A2 (en) 2005-04-29 2006-04-27 Novel method for preventing or treating m tuberculosis infection

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1020127008426A Division KR20120089475A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법
KR1020137024859A Division KR20130110233A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법

Publications (2)

Publication Number Publication Date
KR20080021624A KR20080021624A (ko) 2008-03-07
KR101352806B1 true KR101352806B1 (ko) 2014-02-17

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Family Applications (4)

Application Number Title Priority Date Filing Date
KR1020077027885A Expired - Fee Related KR101352806B1 (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법
KR1020127008426A Ceased KR20120089475A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법
KR20157004060A Ceased KR20150036658A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법
KR1020137024859A Ceased KR20130110233A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법

Family Applications After (3)

Application Number Title Priority Date Filing Date
KR1020127008426A Ceased KR20120089475A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법
KR20157004060A Ceased KR20150036658A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법
KR1020137024859A Ceased KR20130110233A (ko) 2005-04-29 2006-04-27 결핵균 감염을 예방 또는 치료하기 위한 신규한 방법

Country Status (24)

Country Link
US (6) US8470338B2 (enExample)
EP (3) EP2457926B1 (enExample)
JP (4) JP5164830B2 (enExample)
KR (4) KR101352806B1 (enExample)
CN (3) CN106390108B (enExample)
AT (1) ATE543832T1 (enExample)
AU (1) AU2006243357B2 (enExample)
BR (1) BRPI0611347A2 (enExample)
CA (2) CA2821389C (enExample)
CY (1) CY1112851T1 (enExample)
DK (3) DK2457926T3 (enExample)
EA (1) EA012576B1 (enExample)
ES (3) ES2381492T3 (enExample)
HR (3) HRP20120331T1 (enExample)
IL (2) IL186654A (enExample)
MA (1) MA29678B1 (enExample)
NO (3) NO340766B1 (enExample)
NZ (1) NZ562729A (enExample)
PH (1) PH12013502449A1 (enExample)
PL (3) PL2457926T3 (enExample)
PT (3) PT2426141E (enExample)
SI (3) SI2426141T1 (enExample)
WO (1) WO2006117240A2 (enExample)
ZA (1) ZA200709209B (enExample)

Cited By (1)

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KR102534846B1 (ko) 2021-12-14 2023-05-19 재단법인 환동해산업연구원 결핵균에 항균 활성을 가지는 해조류 추출물

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