KR101237152B1 - Ｇｌｐ-１ 및 엑센딘 관련 발명 - Google Patents

Ｇｌｐ-１ 및 엑센딘 관련 발명 Download PDF

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Publication number
KR101237152B1
KR101237152B1 KR1020077007577A KR20077007577A KR101237152B1 KR 101237152 B1 KR101237152 B1 KR 101237152B1 KR 1020077007577 A KR1020077007577 A KR 1020077007577A KR 20077007577 A KR20077007577 A KR 20077007577A KR 101237152 B1 KR101237152 B1 KR 101237152B1
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KR
South Korea
Prior art keywords
exendin
glp
delete delete
peptide
receptor
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Expired - Fee Related
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KR1020077007577A
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English (en)
Korean (ko)
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KR20070093960A (ko
Inventor
마르틴 고트하르트
마르틴 베헤
토마스 베어
부르카르트 요트. 괴케
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필립스-유니버시태트 마르부르크
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Publication of KR20070093960A publication Critical patent/KR20070093960A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Optics & Photonics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
KR1020077007577A 2004-09-03 2005-08-26 Ｇｌｐ-１ 및 엑센딘 관련 발명 Expired - Fee Related KR101237152B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004043153.1 2004-09-03
DE102004043153A DE102004043153B4 (de) 2004-09-03 2004-09-03 Erfindung betreffend GLP-1 und Exendin
PCT/DE2005/001503 WO2006024275A2 (de) 2004-09-03 2005-08-26 Erfindung betreffend glp-1 und exendin

Publications (2)

Publication Number Publication Date
KR20070093960A KR20070093960A (ko) 2007-09-19
KR101237152B1 true KR101237152B1 (ko) 2013-03-04

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KR1020077007577A Expired - Fee Related KR101237152B1 (ko) 2004-09-03 2005-08-26 Ｇｌｐ-１ 및 엑센딘 관련 발명

Country Status (16)

Country Link
US (2) US8268781B2 (enExample)
EP (3) EP2301962B1 (enExample)
JP (1) JP5047795B2 (enExample)
KR (1) KR101237152B1 (enExample)
CN (3) CN102358752B (enExample)
AT (1) ATE486090T1 (enExample)
AU (1) AU2005279537C1 (enExample)
BR (1) BRPI0515624A (enExample)
CA (2) CA2578252A1 (enExample)
DE (2) DE102004043153B4 (enExample)
HR (1) HRP20110061T1 (enExample)
MX (1) MX2007002455A (enExample)
NO (1) NO20071592L (enExample)
PL (2) PL2070946T3 (enExample)
RU (3) RU2489443C2 (enExample)
WO (1) WO2006024275A2 (enExample)

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WO2011019020A1 (ja) * 2009-08-10 2011-02-17 国立大学法人京都大学 膵島イメージング用分子プローブ及びその前駆体、並びに、それらの使用
WO2011027584A1 (ja) * 2009-09-04 2011-03-10 国立大学法人京都大学 膵島イメージング用分子プローブ及びその使用
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TWI617574B (zh) * 2012-12-11 2018-03-11 梅迪繆思有限公司 用於治療肥胖之升糖素與ｇｌｐ－１共促效劑
HUE035803T2 (en) 2012-12-21 2018-05-28 Sanofi Sa Dual GLP1 / GIP or trigonal GLP1 / GIP / glucagon agonists
CN103344764B (zh) * 2013-06-19 2014-11-26 天津美德太平洋科技有限公司 胰高血糖素样肽-1生物学活性检测试剂及检测方法和试剂盒
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Also Published As

Publication number Publication date
PL2301962T3 (pl) 2014-05-30
WO2006024275A3 (de) 2006-11-30
KR20070093960A (ko) 2007-09-19
US20130095037A1 (en) 2013-04-18
EP2301962B1 (de) 2013-10-30
DE502005010449D1 (de) 2010-12-09
HRP20110061T1 (hr) 2011-02-28
US20090180953A1 (en) 2009-07-16
BRPI0515624A (pt) 2008-07-29
EP2070946A3 (de) 2009-09-09
EP2070946B1 (de) 2013-05-29
WO2006024275A2 (de) 2006-03-09
MX2007002455A (es) 2007-10-10
AU2005279537A1 (en) 2006-03-09
ATE486090T1 (de) 2010-11-15
RU2007112115A (ru) 2008-10-10
JP2008511557A (ja) 2008-04-17
US8268781B2 (en) 2012-09-18
JP5047795B2 (ja) 2012-10-10
RU2010148447A (ru) 2012-06-10
EP2301962A3 (de) 2011-11-02
AU2005279537C1 (en) 2012-07-05
RU2486197C2 (ru) 2013-06-27
RU2420536C2 (ru) 2011-06-10
RU2010148446A (ru) 2012-06-10
AU2005279537B2 (en) 2012-02-16
DE102004043153A1 (de) 2006-03-23
RU2489443C2 (ru) 2013-08-10
CN102358752A (zh) 2012-02-22
EP2070946A2 (de) 2009-06-17
DE102004043153B4 (de) 2013-11-21
CA2797666A1 (en) 2006-03-09
EP1784422A2 (de) 2007-05-16
CN101010340B (zh) 2012-11-28
CN101010340A (zh) 2007-08-01
CN102304179A (zh) 2012-01-04
NO20071592L (no) 2007-05-29
EP1784422B1 (de) 2010-10-27
CA2578252A1 (en) 2006-03-09
PL2070946T3 (pl) 2013-09-30
EP2301962A2 (de) 2011-03-30
CN102358752B (zh) 2014-07-30

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