KR101205194B1 - 제2형 당뇨병에 대한 표적으로서의 ριμ-3 키나제 - Google Patents

제2형 당뇨병에 대한 표적으로서의 ριμ-3 키나제 Download PDF

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KR101205194B1
KR101205194B1 KR1020117001551A KR20117001551A KR101205194B1 KR 101205194 B1 KR101205194 B1 KR 101205194B1 KR 1020117001551 A KR1020117001551 A KR 1020117001551A KR 20117001551 A KR20117001551 A KR 20117001551A KR 101205194 B1 KR101205194 B1 KR 101205194B1
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pim
protein
seq
ability
activity
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KR1020117001551A
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Korean (ko)
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KR20110011753A (ko
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마르쿠스 코른
귄터 뮐러
루돌프 슈나이더
게오르그 찬크
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사노피-아벤티스 도이칠란트 게엠베하
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Publication of KR20110011753A publication Critical patent/KR20110011753A/ko
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Publication of KR101205194B1 publication Critical patent/KR101205194B1/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Plant Pathology (AREA)
  • Obesity (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020117001551A 2002-01-19 2003-01-20 제2형 당뇨병에 대한 표적으로서의 ριμ-3 키나제 KR101205194B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02001401 2002-01-19
EP02001401.5 2002-01-19
PCT/EP2003/000492 WO2003060130A2 (en) 2002-01-19 2003-01-20 Pim-3 kinase as a target for type 2 diabetes mellitus

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020047011189A Division KR101158326B1 (ko) 2002-01-19 2003-01-20 제2형 당뇨병에 대한 표적으로서의 ριμ-3 키나제

Publications (2)

Publication Number Publication Date
KR20110011753A KR20110011753A (ko) 2011-02-08
KR101205194B1 true KR101205194B1 (ko) 2012-11-27

Family

ID=8185311

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020047011189A KR101158326B1 (ko) 2002-01-19 2003-01-20 제2형 당뇨병에 대한 표적으로서의 ριμ-3 키나제
KR1020117001551A KR101205194B1 (ko) 2002-01-19 2003-01-20 제2형 당뇨병에 대한 표적으로서의 ριμ-3 키나제

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020047011189A KR101158326B1 (ko) 2002-01-19 2003-01-20 제2형 당뇨병에 대한 표적으로서의 ριμ-3 키나제

Country Status (14)

Country Link
EP (1) EP1468092B1 (de)
JP (1) JP4272533B2 (de)
KR (2) KR101158326B1 (de)
CN (1) CN100467601C (de)
AT (1) ATE541040T1 (de)
BR (1) BR0306984A (de)
CA (2) CA2473566C (de)
DK (1) DK1468092T3 (de)
IL (1) IL194074A (de)
MX (1) MXPA04006906A (de)
NO (1) NO333253B1 (de)
RU (1) RU2316598C2 (de)
WO (1) WO2003060130A2 (de)
ZA (1) ZA200404997B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2555323A1 (en) * 2003-08-11 2005-02-17 Kureha Corporation Polypeptide specific to liver cancer, polynucleotide coding for the polypeptide, and rna molecule suppressing expression of the polypeptide
CA3144712A1 (en) * 2019-06-27 2020-12-30 Industrial Cooperation Foundation Chonbuk National University Novel adp-ribosyl cyclase and inhibitor thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0911391A3 (de) * 1997-10-24 2000-01-19 Smithkline Beecham Corporation Klon HWHHJ20
US6143540A (en) * 1999-01-26 2000-11-07 Millennium Pharmaceuticals, Inc. Molecules of the HKID-1-related protein family and uses thereof
CN1328134A (zh) * 2001-04-13 2001-12-26 复旦大学 一种蛋白激酶编码序列,其编码的多肽、制法及用途
DE10123055A1 (de) * 2001-05-11 2003-03-20 Gruenenthal Gmbh Screeningverfahren mit PIM1-Kinase oder PIM3-Kinase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GenBank Accession Number BC017621(2001.11.30.)*

Also Published As

Publication number Publication date
DK1468092T3 (da) 2012-05-07
MXPA04006906A (es) 2004-12-06
NO333253B1 (no) 2013-04-22
WO2003060130A3 (en) 2004-01-15
EP1468092A2 (de) 2004-10-20
EP1468092B1 (de) 2012-01-11
NO20043459L (no) 2004-10-07
CA2680946A1 (en) 2003-07-24
CA2473566A1 (en) 2003-07-24
KR20110011753A (ko) 2011-02-08
KR20040075940A (ko) 2004-08-30
KR101158326B1 (ko) 2012-06-28
JP2005514068A (ja) 2005-05-19
RU2004125291A (ru) 2005-04-20
IL194074A (en) 2011-08-31
AU2003202579A1 (en) 2003-07-30
WO2003060130A2 (en) 2003-07-24
JP4272533B2 (ja) 2009-06-03
CA2680946C (en) 2013-03-12
CA2473566C (en) 2012-05-01
BR0306984A (pt) 2004-12-14
RU2316598C2 (ru) 2008-02-10
CN1620505A (zh) 2005-05-25
CN100467601C (zh) 2009-03-11
ZA200404997B (en) 2006-05-31
ATE541040T1 (de) 2012-01-15

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