KR101060972B1 - 항콜린제를 함유하는 흡입용 에어로졸 제형 - Google Patents

항콜린제를 함유하는 흡입용 에어로졸 제형 Download PDF

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Publication number
KR101060972B1
KR101060972B1 KR1020057002504A KR20057002504A KR101060972B1 KR 101060972 B1 KR101060972 B1 KR 101060972B1 KR 1020057002504 A KR1020057002504 A KR 1020057002504A KR 20057002504 A KR20057002504 A KR 20057002504A KR 101060972 B1 KR101060972 B1 KR 101060972B1
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KR
South Korea
Prior art keywords
acid
aqueous pharmaceutical
pharmaceutical formulation
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020057002504A
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English (en)
Korean (ko)
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KR20050049478A (ko
Inventor
프리드리히 슈미트
Original Assignee
베링거 잉겔하임 파르마 게엠베하 운트 코 카게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31979448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101060972(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10237232A external-priority patent/DE10237232A1/de
Application filed by 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 filed Critical 베링거 잉겔하임 파르마 게엠베하 운트 코 카게
Publication of KR20050049478A publication Critical patent/KR20050049478A/ko
Application granted granted Critical
Publication of KR101060972B1 publication Critical patent/KR101060972B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020057002504A 2002-08-14 2003-07-25 항콜린제를 함유하는 흡입용 에어로졸 제형 Expired - Fee Related KR101060972B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10237232A DE10237232A1 (de) 2002-08-14 2002-08-14 Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE10237232.2 2002-08-14
DE10240257 2002-08-31
DE10240257.4 2002-08-31
PCT/EP2003/008221 WO2004022052A1 (de) 2002-08-14 2003-07-25 Aerosolformulierung für die inhalation enthaltend ein anticholinergikum

Publications (2)

Publication Number Publication Date
KR20050049478A KR20050049478A (ko) 2005-05-25
KR101060972B1 true KR101060972B1 (ko) 2011-09-01

Family

ID=31979448

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057002504A Expired - Fee Related KR101060972B1 (ko) 2002-08-14 2003-07-25 항콜린제를 함유하는 흡입용 에어로졸 제형

Country Status (31)

Country Link
EP (2) EP1908468A1 (enExample)
JP (1) JP4602767B2 (enExample)
KR (1) KR101060972B1 (enExample)
CN (1) CN1674887A (enExample)
AT (1) ATE400265T1 (enExample)
AU (1) AU2003298473B9 (enExample)
BR (1) BR0313457A (enExample)
CA (1) CA2495275C (enExample)
CY (1) CY1108776T1 (enExample)
DE (1) DE50310117D1 (enExample)
DK (1) DK1530464T3 (enExample)
EA (1) EA009936B1 (enExample)
EC (1) ECSP055600A (enExample)
ES (1) ES2305479T3 (enExample)
HR (1) HRP20050132A2 (enExample)
IL (1) IL166814A (enExample)
MX (1) MXPA05001595A (enExample)
MY (1) MY142579A (enExample)
NO (1) NO20051287L (enExample)
NZ (1) NZ538743A (enExample)
PE (1) PE20040372A1 (enExample)
PL (1) PL375511A1 (enExample)
PT (1) PT1530464E (enExample)
RS (1) RS51396B (enExample)
SA (1) SA03240265B1 (enExample)
SI (1) SI1530464T1 (enExample)
TW (1) TWI317279B (enExample)
UA (1) UA81775C2 (enExample)
UY (1) UY27938A1 (enExample)
WO (1) WO2004022052A1 (enExample)
ZA (1) ZA200410325B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038885A1 (de) * 2004-08-10 2006-02-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005001297A1 (de) * 2005-01-12 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055960A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055963A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055957A1 (de) * 2005-11-24 2007-07-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055958A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
EA026241B1 (ru) 2009-11-25 2017-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Распылитель
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
US10508280B2 (en) 2014-01-31 2019-12-17 AgBiome, Inc. Modified biological control agents and their uses
US9877486B2 (en) 2014-01-31 2018-01-30 AgBiome, Inc. Methods of growing plants using modified biological control agents
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
AU2015258107B2 (en) 2014-05-07 2019-12-19 Boehringer Ingelheim International Gmbh Nebulizer
WO2015169732A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Container, nebulizer and use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027959A2 (de) * 1996-12-20 1998-07-02 Boehringer Ingelheim Pharma Kg Neue wässerige arzneimittelzubereitungen zur erzeugung treibgasfreier aerosole
WO2002032899A1 (de) * 2000-10-14 2002-04-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue als arzneimittel einsetzbare anticholinergika sowie verfahren zu deren herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
CN1213732C (zh) * 2000-05-22 2005-08-10 奇斯药制品公司 用于加压计量吸入器的稳定药用溶液制剂
DE10063957A1 (de) * 2000-12-20 2002-06-27 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Dopamin-Agonisten
DE10200943A1 (de) * 2002-01-12 2003-07-24 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Scopinestern

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027959A2 (de) * 1996-12-20 1998-07-02 Boehringer Ingelheim Pharma Kg Neue wässerige arzneimittelzubereitungen zur erzeugung treibgasfreier aerosole
WO2002032899A1 (de) * 2000-10-14 2002-04-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue als arzneimittel einsetzbare anticholinergika sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
NO20051287D0 (no) 2005-03-11
IL166814A0 (en) 2006-01-15
BR0313457A (pt) 2005-06-21
MXPA05001595A (es) 2005-04-25
TWI317279B (en) 2009-11-21
EA009936B1 (ru) 2008-04-28
CY1108776T1 (el) 2014-04-09
JP2006506345A (ja) 2006-02-23
CA2495275C (en) 2012-04-17
NO20051287L (no) 2005-03-11
DK1530464T3 (da) 2008-09-08
PE20040372A1 (es) 2004-08-03
UY27938A1 (es) 2004-03-31
MY142579A (en) 2010-12-15
AU2003298473B9 (en) 2011-06-09
EP1530464B1 (de) 2008-07-09
AU2003298473A1 (en) 2004-03-29
EP1530464A1 (de) 2005-05-18
AU2003298473B2 (en) 2009-04-23
WO2004022052A1 (de) 2004-03-18
ECSP055600A (es) 2005-04-18
ES2305479T3 (es) 2008-11-01
EA200500292A1 (ru) 2005-10-27
HRP20050132A2 (en) 2006-05-31
DE50310117D1 (de) 2008-08-21
RS20050074A (sr) 2007-09-21
KR20050049478A (ko) 2005-05-25
CN1674887A (zh) 2005-09-28
PT1530464E (pt) 2008-08-28
EP1908468A1 (de) 2008-04-09
RS51396B (sr) 2011-02-28
ZA200410325B (en) 2006-10-25
ATE400265T1 (de) 2008-07-15
UA81775C2 (uk) 2008-02-11
TW200406213A (en) 2004-05-01
CA2495275A1 (en) 2004-03-18
SA03240265B1 (ar) 2009-11-10
PL375511A1 (en) 2005-11-28
SI1530464T1 (sl) 2008-12-31
IL166814A (en) 2010-11-30
NZ538743A (en) 2006-05-26
JP4602767B2 (ja) 2010-12-22

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