AU2003298473B9 - Aerosol formulation for inhalation containing an anticholinergic agent - Google Patents

Aerosol formulation for inhalation containing an anticholinergic agent Download PDF

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Publication number
AU2003298473B9
AU2003298473B9 AU2003298473A AU2003298473A AU2003298473B9 AU 2003298473 B9 AU2003298473 B9 AU 2003298473B9 AU 2003298473 A AU2003298473 A AU 2003298473A AU 2003298473 A AU2003298473 A AU 2003298473A AU 2003298473 B9 AU2003298473 B9 AU 2003298473B9
Authority
AU
Australia
Prior art keywords
acid
spring
formulation
nozzle
inhalation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003298473A
Other languages
English (en)
Other versions
AU2003298473A1 (en
AU2003298473B2 (en
Inventor
Friedrich Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31979448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2003298473(B9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10237232A external-priority patent/DE10237232A1/de
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG, Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Publication of AU2003298473A1 publication Critical patent/AU2003298473A1/en
Application granted granted Critical
Publication of AU2003298473B2 publication Critical patent/AU2003298473B2/en
Publication of AU2003298473B9 publication Critical patent/AU2003298473B9/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2003298473A 2002-08-14 2003-07-25 Aerosol formulation for inhalation containing an anticholinergic agent Ceased AU2003298473B9 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10237232A DE10237232A1 (de) 2002-08-14 2002-08-14 Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE10237232.2 2002-08-14
DE10240257 2002-08-31
DE10240257.4 2002-08-31
PCT/EP2003/008221 WO2004022052A1 (de) 2002-08-14 2003-07-25 Aerosolformulierung für die inhalation enthaltend ein anticholinergikum

Publications (3)

Publication Number Publication Date
AU2003298473A1 AU2003298473A1 (en) 2004-03-29
AU2003298473B2 AU2003298473B2 (en) 2009-04-23
AU2003298473B9 true AU2003298473B9 (en) 2011-06-09

Family

ID=31979448

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003298473A Ceased AU2003298473B9 (en) 2002-08-14 2003-07-25 Aerosol formulation for inhalation containing an anticholinergic agent

Country Status (31)

Country Link
EP (2) EP1908468A1 (enExample)
JP (1) JP4602767B2 (enExample)
KR (1) KR101060972B1 (enExample)
CN (1) CN1674887A (enExample)
AT (1) ATE400265T1 (enExample)
AU (1) AU2003298473B9 (enExample)
BR (1) BR0313457A (enExample)
CA (1) CA2495275C (enExample)
CY (1) CY1108776T1 (enExample)
DE (1) DE50310117D1 (enExample)
DK (1) DK1530464T3 (enExample)
EA (1) EA009936B1 (enExample)
EC (1) ECSP055600A (enExample)
ES (1) ES2305479T3 (enExample)
HR (1) HRP20050132A2 (enExample)
IL (1) IL166814A (enExample)
MX (1) MXPA05001595A (enExample)
MY (1) MY142579A (enExample)
NO (1) NO20051287L (enExample)
NZ (1) NZ538743A (enExample)
PE (1) PE20040372A1 (enExample)
PL (1) PL375511A1 (enExample)
PT (1) PT1530464E (enExample)
RS (1) RS51396B (enExample)
SA (1) SA03240265B1 (enExample)
SI (1) SI1530464T1 (enExample)
TW (1) TWI317279B (enExample)
UA (1) UA81775C2 (enExample)
UY (1) UY27938A1 (enExample)
WO (1) WO2004022052A1 (enExample)
ZA (1) ZA200410325B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038885A1 (de) * 2004-08-10 2006-02-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005001297A1 (de) * 2005-01-12 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055960A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055963A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055957A1 (de) * 2005-11-24 2007-07-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055958A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
EA026241B1 (ru) 2009-11-25 2017-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Распылитель
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
US10508280B2 (en) 2014-01-31 2019-12-17 AgBiome, Inc. Modified biological control agents and their uses
US9877486B2 (en) 2014-01-31 2018-01-30 AgBiome, Inc. Methods of growing plants using modified biological control agents
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
AU2015258107B2 (en) 2014-05-07 2019-12-19 Boehringer Ingelheim International Gmbh Nebulizer
WO2015169732A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Container, nebulizer and use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001089480A1 (en) * 2000-05-22 2001-11-29 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers
WO2002032899A1 (de) * 2000-10-14 2002-04-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue als arzneimittel einsetzbare anticholinergika sowie verfahren zu deren herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
DE10063957A1 (de) * 2000-12-20 2002-06-27 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Dopamin-Agonisten
DE10200943A1 (de) * 2002-01-12 2003-07-24 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Scopinestern

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001089480A1 (en) * 2000-05-22 2001-11-29 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers
WO2002032899A1 (de) * 2000-10-14 2002-04-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue als arzneimittel einsetzbare anticholinergika sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
NO20051287D0 (no) 2005-03-11
IL166814A0 (en) 2006-01-15
BR0313457A (pt) 2005-06-21
MXPA05001595A (es) 2005-04-25
TWI317279B (en) 2009-11-21
EA009936B1 (ru) 2008-04-28
CY1108776T1 (el) 2014-04-09
JP2006506345A (ja) 2006-02-23
CA2495275C (en) 2012-04-17
NO20051287L (no) 2005-03-11
DK1530464T3 (da) 2008-09-08
PE20040372A1 (es) 2004-08-03
UY27938A1 (es) 2004-03-31
MY142579A (en) 2010-12-15
EP1530464B1 (de) 2008-07-09
AU2003298473A1 (en) 2004-03-29
KR101060972B1 (ko) 2011-09-01
EP1530464A1 (de) 2005-05-18
AU2003298473B2 (en) 2009-04-23
WO2004022052A1 (de) 2004-03-18
ECSP055600A (es) 2005-04-18
ES2305479T3 (es) 2008-11-01
EA200500292A1 (ru) 2005-10-27
HRP20050132A2 (en) 2006-05-31
DE50310117D1 (de) 2008-08-21
RS20050074A (sr) 2007-09-21
KR20050049478A (ko) 2005-05-25
CN1674887A (zh) 2005-09-28
PT1530464E (pt) 2008-08-28
EP1908468A1 (de) 2008-04-09
RS51396B (sr) 2011-02-28
ZA200410325B (en) 2006-10-25
ATE400265T1 (de) 2008-07-15
UA81775C2 (uk) 2008-02-11
TW200406213A (en) 2004-05-01
CA2495275A1 (en) 2004-03-18
SA03240265B1 (ar) 2009-11-10
PL375511A1 (en) 2005-11-28
SI1530464T1 (sl) 2008-12-31
IL166814A (en) 2010-11-30
NZ538743A (en) 2006-05-26
JP4602767B2 (ja) 2010-12-22

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
SREP Specification republished
MK14 Patent ceased section 143(a) (annual fees not paid) or expired