KR101005717B1 - 무수물의 ｈｆａ-현탁 제형 - Google Patents

무수물의 ｈｆａ-현탁 제형 Download PDF

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Publication number
KR101005717B1
KR101005717B1 KR1020047015174A KR20047015174A KR101005717B1 KR 101005717 B1 KR101005717 B1 KR 101005717B1 KR 1020047015174 A KR1020047015174 A KR 1020047015174A KR 20047015174 A KR20047015174 A KR 20047015174A KR 101005717 B1 KR101005717 B1 KR 101005717B1
Authority
KR
South Korea
Prior art keywords
suspension
hfa
acid
tiotropium bromide
tiotropium
Prior art date
Application number
KR1020047015174A
Other languages
English (en)
Korean (ko)
Other versions
KR20040098022A (ko
Inventor
슈멜쩨르크리슈텔
Original Assignee
베링거 잉겔하임 파르마 게엠베하 운트 코 카게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 filed Critical 베링거 잉겔하임 파르마 게엠베하 운트 코 카게
Publication of KR20040098022A publication Critical patent/KR20040098022A/ko
Application granted granted Critical
Publication of KR101005717B1 publication Critical patent/KR101005717B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
KR1020047015174A 2002-03-28 2003-03-20 무수물의 ｈｆａ-현탁 제형 KR101005717B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10214264A DE10214264A1 (de) 2002-03-28 2002-03-28 HFA-Suspensionsformulierungen eines Anhydrats
DE10214264.5 2002-03-28
PCT/EP2003/002899 WO2003082244A2 (de) 2002-03-28 2003-03-20 Hfa-suspensionsformulierungen eines anhydrats

Publications (2)

Publication Number Publication Date
KR20040098022A KR20040098022A (ko) 2004-11-18
KR101005717B1 true KR101005717B1 (ko) 2011-01-05

Family

ID=28050990

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047015174A KR101005717B1 (ko) 2002-03-28 2003-03-20 무수물의 ｈｆａ-현탁 제형

Country Status (21)

Country Link
EP (1) EP1492498A2 (ja)
JP (1) JP5147158B2 (ja)
KR (1) KR101005717B1 (ja)
CN (1) CN1642525A (ja)
AU (1) AU2003221509B2 (ja)
BR (1) BR0308709A (ja)
CA (1) CA2479638C (ja)
DE (1) DE10214264A1 (ja)
EA (1) EA008610B1 (ja)
EC (1) ECSP045322A (ja)
HR (1) HRP20040890A2 (ja)
IL (1) IL163696A0 (ja)
ME (1) ME00246B (ja)
MX (1) MXPA04009338A (ja)
NO (1) NO20044004L (ja)
NZ (1) NZ536030A (ja)
PL (1) PL371295A1 (ja)
RS (1) RS52481B (ja)
UA (1) UA79776C2 (ja)
WO (1) WO2003082244A2 (ja)
ZA (1) ZA200405637B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2007144531A (ru) * 2005-05-02 2009-06-10 БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) Новые кристаллические формы тиотропийбромида
AU2006243238B2 (en) * 2005-05-02 2012-05-24 Boehringer Ingelheim International Gmbh Novel crystalline forms of tiotropium bromide
AU2015201037C1 (en) * 2009-05-29 2017-07-27 Pearl Therapeutics, Inc. Respiratory delivery of active agents
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
PL3111926T3 (pl) * 2009-05-29 2020-06-29 Pearl Therapeutics, Inc. Kompozycje, sposoby i układy do dostarczania dwóch lub większej liczby środków czynnych do układu oddechowego
US20140275517A1 (en) 2013-03-15 2014-09-18 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials
JP6781831B2 (ja) * 2016-09-19 2020-11-04 メキシケム フロー エセ・ア・デ・セ・ヴェ 医薬組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000007567A1 (de) * 1998-08-04 2000-02-17 Jago Research Ag Medizinische aerosolformulierungen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
GB0009605D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medicaments
GB0009583D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
GB0009606D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
DE10113366A1 (de) * 2001-03-20 2002-09-26 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Endothelinantagonisten
DE50115277D1 (de) * 2000-10-31 2010-02-04 Boehringer Ingelheim Pharma Arzneimittelkompositionen aus tiotropiumsalzen und
DE10111058A1 (de) * 2001-03-08 2002-09-12 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und NK¶1¶-Rezeptor-Antagonisten

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000007567A1 (de) * 1998-08-04 2000-02-17 Jago Research Ag Medizinische aerosolformulierungen

Also Published As

Publication number Publication date
BR0308709A (pt) 2005-01-04
JP2005527550A (ja) 2005-09-15
UA79776C2 (en) 2007-07-25
JP5147158B2 (ja) 2013-02-20
HRP20040890A2 (en) 2005-06-30
RS52481B (en) 2013-02-28
MXPA04009338A (es) 2005-01-25
NZ536030A (en) 2006-07-28
AU2003221509A1 (en) 2003-10-13
EP1492498A2 (de) 2005-01-05
DE10214264A1 (de) 2003-10-16
CN1642525A (zh) 2005-07-20
AU2003221509B2 (en) 2008-01-24
ZA200405637B (en) 2005-07-27
WO2003082244A2 (de) 2003-10-09
IL163696A0 (en) 2005-12-18
CA2479638C (en) 2011-01-04
PL371295A1 (en) 2005-06-13
MEP47308A (en) 2011-02-10
ECSP045322A (es) 2005-01-28
EA200401159A1 (ru) 2005-04-28
ME00246B (me) 2011-05-10
EA008610B1 (ru) 2007-06-29
CA2479638A1 (en) 2003-10-09
WO2003082244A3 (de) 2004-02-05
KR20040098022A (ko) 2004-11-18
YU86004A (sh) 2006-08-17
NO20044004L (no) 2004-10-05

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