EA200401159A1 - Содержащие пропеллент hfa суспензионные препараты на основе ангидрата - Google Patents

Содержащие пропеллент hfa суспензионные препараты на основе ангидрата

Info

Publication number
EA200401159A1
EA200401159A1 EA200401159A EA200401159A EA200401159A1 EA 200401159 A1 EA200401159 A1 EA 200401159A1 EA 200401159 A EA200401159 A EA 200401159A EA 200401159 A EA200401159 A EA 200401159A EA 200401159 A1 EA200401159 A1 EA 200401159A1
Authority
EA
Eurasian Patent Office
Prior art keywords
anhydrate
preparations based
suspension preparations
propellent
hfa suspension
Prior art date
Application number
EA200401159A
Other languages
English (en)
Other versions
EA008610B1 (ru
Inventor
Кристель Шмельцер
Original Assignee
Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг filed Critical Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Publication of EA200401159A1 publication Critical patent/EA200401159A1/ru
Publication of EA008610B1 publication Critical patent/EA008610B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Abstract

В заявке описаны содержащие пропелленты суспензионные препараты на основе кристаллического ангидрата (1α,2β,4β,5α,7β)-7-[(гидроксиди-2-тиенилацетил)окси]-9,9-диметил-3-окса-9-азониатрицикло[3.3.1.0]нонанбромида.Отчет о международном поиске был опубликован 2004.02.05.
EA200401159A 2002-03-28 2003-03-20 Суспензионные препараты на основе кристаллического ангидрата тиотропийбромида EA008610B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10214264A DE10214264A1 (de) 2002-03-28 2002-03-28 HFA-Suspensionsformulierungen eines Anhydrats
PCT/EP2003/002899 WO2003082244A2 (de) 2002-03-28 2003-03-20 Hfa-suspensionsformulierungen eines anhydrats

Publications (2)

Publication Number Publication Date
EA200401159A1 true EA200401159A1 (ru) 2005-04-28
EA008610B1 EA008610B1 (ru) 2007-06-29

Family

ID=28050990

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401159A EA008610B1 (ru) 2002-03-28 2003-03-20 Суспензионные препараты на основе кристаллического ангидрата тиотропийбромида

Country Status (21)

Country Link
EP (1) EP1492498A2 (ru)
JP (1) JP5147158B2 (ru)
KR (1) KR101005717B1 (ru)
CN (1) CN1642525A (ru)
AU (1) AU2003221509B2 (ru)
BR (1) BR0308709A (ru)
CA (1) CA2479638C (ru)
DE (1) DE10214264A1 (ru)
EA (1) EA008610B1 (ru)
EC (1) ECSP045322A (ru)
HR (1) HRP20040890A2 (ru)
IL (1) IL163696A0 (ru)
ME (1) ME00246B (ru)
MX (1) MXPA04009338A (ru)
NO (1) NO20044004L (ru)
NZ (1) NZ536030A (ru)
PL (1) PL371295A1 (ru)
RS (1) RS52481B (ru)
UA (1) UA79776C2 (ru)
WO (1) WO2003082244A2 (ru)
ZA (1) ZA200405637B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1881980E (pt) * 2005-05-02 2012-12-06 Boehringer Ingelheim Int Novas formas cristalinas de brometo de tiotrópio
CA2606552A1 (en) * 2005-05-02 2006-11-09 Boehringer Ingelheim International Gmbh Crystalline forms of tiotropium bromide
AU2015201037C1 (en) * 2009-05-29 2017-07-27 Pearl Therapeutics, Inc. Respiratory delivery of active agents
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
TWI792140B (zh) * 2009-05-29 2023-02-11 美商沛爾醫療股份有限公司 用於經由呼吸道遞送二或更多種活性藥劑的組成物、方法與系統
TR201902687T4 (tr) 2013-03-15 2019-03-21 Pearl Therapeutics Inc İri parçacıklı kristal malzemelerin koşullandırılması için yöntemler ve sistemler.
EP3515439B1 (en) * 2016-09-19 2021-12-15 Mexichem Fluor S.A. de C.V. Pharmaceutical composition comprising tiotropium bromide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DK1102579T3 (da) * 1998-08-04 2003-07-14 Jago Res Ag Medicinske aerosolformuleringer
GB0009583D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
GB0009605D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medicaments
GB0009606D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
DE10111058A1 (de) * 2001-03-08 2002-09-12 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und NK¶1¶-Rezeptor-Antagonisten
DE10113366A1 (de) * 2001-03-20 2002-09-26 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Endothelinantagonisten
AU2002214030A1 (en) * 2000-10-31 2002-05-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Novel medicament compositions consisting of tiotropium salts and antihistamines for treating respiratory illnesses

Also Published As

Publication number Publication date
NO20044004L (no) 2004-10-05
HRP20040890A2 (en) 2005-06-30
NZ536030A (en) 2006-07-28
CA2479638C (en) 2011-01-04
ME00246B (me) 2011-05-10
KR20040098022A (ko) 2004-11-18
EP1492498A2 (de) 2005-01-05
PL371295A1 (en) 2005-06-13
JP5147158B2 (ja) 2013-02-20
ECSP045322A (es) 2005-01-28
CN1642525A (zh) 2005-07-20
CA2479638A1 (en) 2003-10-09
EA008610B1 (ru) 2007-06-29
RS52481B (en) 2013-02-28
KR101005717B1 (ko) 2011-01-05
MEP47308A (en) 2011-02-10
MXPA04009338A (es) 2005-01-25
WO2003082244A3 (de) 2004-02-05
YU86004A (sh) 2006-08-17
UA79776C2 (en) 2007-07-25
AU2003221509B2 (en) 2008-01-24
DE10214264A1 (de) 2003-10-16
WO2003082244A2 (de) 2003-10-09
JP2005527550A (ja) 2005-09-15
BR0308709A (pt) 2005-01-04
ZA200405637B (en) 2005-07-27
AU2003221509A1 (en) 2003-10-13
IL163696A0 (en) 2005-12-18

Similar Documents

Publication Publication Date Title
TW200617007A (en) Crystalline anticholinergic and its use for preparing a pharmaceutical composition
YU50903A (sh) Postupak za pripremanje antiholinergikuma,tiotropijumbromida
EA200401142A1 (ru) Микронизированный кристаллический тиотропийбромид
CY1105543T1 (el) Σκευασματα εναιωρηματων με hfa που περιεχουν αντιχολινεργικο
YU27303A (sh) Kristalni monohidrat, postupak za njegovo pripremanje i njegova primena za pripremanje leka
UY27751A1 (es) Método para la administración de un anticolinérgico por inhalación
AU2003244450A1 (en) Formulations for inhalation
IE821210L (en) Guanine derivatives
EA200000381A1 (ru) Препарат 2-метил-тиено-бензодиазепина
GB2380675A (en) Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
ES2096560T3 (es) Compuestos de benzocicloheptapiridina sustituida con fluor, composiciones y metodos para uso como compuestos antihistaminicos.
DE69714698T2 (de) Endothelin-antagonisten
AU3573100A (en) Natural language interface for searching database
EA200401159A1 (ru) Содержащие пропеллент hfa суспензионные препараты на основе ангидрата
EP0716083A4 (en) BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND INTERMEDIATES THEREOF
WO2001027110A3 (de) Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate
EP0721942A4 (en) NEW TETRACYCLIC COMPOUND
ID29574A (id) Formulasi 2-metil-tieno-benzodiazepin
EP0635506A4 (en) CONNECTION WITH ANTIPSYCHOTIC EFFECT.
MY114213A (en) Clavulanic acid salts
EP0638569A4 (en) BICYCLIC NITROGEN COMPOUNDS.