EA200401159A1 - CONTAINING PROPELLENT HFA SUSPENSION PREPARATIONS BASED ON ANHYDRATE - Google Patents

CONTAINING PROPELLENT HFA SUSPENSION PREPARATIONS BASED ON ANHYDRATE

Info

Publication number
EA200401159A1
EA200401159A1 EA200401159A EA200401159A EA200401159A1 EA 200401159 A1 EA200401159 A1 EA 200401159A1 EA 200401159 A EA200401159 A EA 200401159A EA 200401159 A EA200401159 A EA 200401159A EA 200401159 A1 EA200401159 A1 EA 200401159A1
Authority
EA
Eurasian Patent Office
Prior art keywords
anhydrate
preparations based
suspension preparations
propellent
hfa suspension
Prior art date
Application number
EA200401159A
Other languages
Russian (ru)
Other versions
EA008610B1 (en
Inventor
Кристель Шмельцер
Original Assignee
Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг filed Critical Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Publication of EA200401159A1 publication Critical patent/EA200401159A1/en
Publication of EA008610B1 publication Critical patent/EA008610B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

В заявке описаны содержащие пропелленты суспензионные препараты на основе кристаллического ангидрата (1α,2β,4β,5α,7β)-7-[(гидроксиди-2-тиенилацетил)окси]-9,9-диметил-3-окса-9-азониатрицикло[3.3.1.0]нонанбромида.Отчет о международном поиске был опубликован 2004.02.05.The application describes propellant-containing suspension preparations based on crystalline anhydrate (1α, 2β, 4β, 5α, 7β) -7 - [(hydroxide-2-thienylacetyl) oxy] -9,9-dimethyl-3-oxa-9-azoniatricyclo [ 3.3.1.0] nonanbromida. The international search report was published on 2004.02.05.

EA200401159A 2002-03-28 2003-03-20 Hfa-suspension formulation of an anhydrate EA008610B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10214264A DE10214264A1 (en) 2002-03-28 2002-03-28 HFA suspension formulations of an anhydrate
PCT/EP2003/002899 WO2003082244A2 (en) 2002-03-28 2003-03-20 Hfa-suspension formulation of an anhydrate

Publications (2)

Publication Number Publication Date
EA200401159A1 true EA200401159A1 (en) 2005-04-28
EA008610B1 EA008610B1 (en) 2007-06-29

Family

ID=28050990

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401159A EA008610B1 (en) 2002-03-28 2003-03-20 Hfa-suspension formulation of an anhydrate

Country Status (21)

Country Link
EP (1) EP1492498A2 (en)
JP (1) JP5147158B2 (en)
KR (1) KR101005717B1 (en)
CN (1) CN1642525A (en)
AU (1) AU2003221509B2 (en)
BR (1) BR0308709A (en)
CA (1) CA2479638C (en)
DE (1) DE10214264A1 (en)
EA (1) EA008610B1 (en)
EC (1) ECSP045322A (en)
HR (1) HRP20040890A2 (en)
IL (1) IL163696A0 (en)
ME (1) ME00246B (en)
MX (1) MXPA04009338A (en)
NO (1) NO20044004L (en)
NZ (1) NZ536030A (en)
PL (1) PL371295A1 (en)
RS (1) RS52481B (en)
UA (1) UA79776C2 (en)
WO (1) WO2003082244A2 (en)
ZA (1) ZA200405637B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080012932A (en) * 2005-05-02 2008-02-12 베링거 인겔하임 인터내셔날 게엠베하 Novel crystalline forms of tiotropium bromide
WO2006117300A2 (en) * 2005-05-02 2006-11-09 Boehringer Ingelheim International Gmbh Crystalline forms of tiotropium bromide
AU2015201037C1 (en) * 2009-05-29 2017-07-27 Pearl Therapeutics, Inc. Respiratory delivery of active agents
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
TWI792140B (en) 2009-05-29 2023-02-11 美商沛爾醫療股份有限公司 Compositions, methods and systems for respiratory delivery of two or more active agents
US20140275517A1 (en) 2013-03-15 2014-09-18 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials
BR112019005120A2 (en) * 2016-09-19 2019-06-04 Mexichem Fluor Sa De Cv pharmaceutical composition, sealed container, metered dose inhaler, and methods for treating a patient suffering or likely to suffer from a respiratory disorder, to improve the stability of a pharmaceutical composition, to improve aerosolization performance upon storage of a composition and to reduce the global warming potential of a pharmaceutical composition.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (en) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Esters of thienyl carboxylic acids with amino alcohols, their quaternization products, processes for their preparation and medicaments containing them
ES2193726T3 (en) * 1998-08-04 2003-11-01 Jago Res Ag MEDICINAL AEROSOL FORMULATIONS.
GB0009606D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
GB0009583D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
GB0009605D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medicaments
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
DE10111058A1 (en) * 2001-03-08 2002-09-12 Boehringer Ingelheim Pharma New drug compositions based on anticholinergics and NK¶1¶ receptor antagonists
DE50115277D1 (en) * 2000-10-31 2010-02-04 Boehringer Ingelheim Pharma DRUG COMPOSITIONS FROM TIOTROPIUM SALTS AND
DE10113366A1 (en) * 2001-03-20 2002-09-26 Boehringer Ingelheim Pharma Medicament for treating inflammatory or obstructive respiratory diseases, e.g. asthma or chronic obstructive pulmonary disease, containing synergistic combination of anticholinergic agent and endothelin antagonist

Also Published As

Publication number Publication date
KR20040098022A (en) 2004-11-18
AU2003221509B2 (en) 2008-01-24
JP2005527550A (en) 2005-09-15
WO2003082244A3 (en) 2004-02-05
DE10214264A1 (en) 2003-10-16
JP5147158B2 (en) 2013-02-20
UA79776C2 (en) 2007-07-25
NO20044004L (en) 2004-10-05
BR0308709A (en) 2005-01-04
NZ536030A (en) 2006-07-28
HRP20040890A2 (en) 2005-06-30
CA2479638C (en) 2011-01-04
IL163696A0 (en) 2005-12-18
CN1642525A (en) 2005-07-20
CA2479638A1 (en) 2003-10-09
ECSP045322A (en) 2005-01-28
EA008610B1 (en) 2007-06-29
ZA200405637B (en) 2005-07-27
KR101005717B1 (en) 2011-01-05
EP1492498A2 (en) 2005-01-05
RS52481B (en) 2013-02-28
MXPA04009338A (en) 2005-01-25
AU2003221509A1 (en) 2003-10-13
WO2003082244A2 (en) 2003-10-09
MEP47308A (en) 2011-02-10
YU86004A (en) 2006-08-17
ME00246B (en) 2011-05-10
PL371295A1 (en) 2005-06-13

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