KR100971093B1 - 치환된 4-아미노-2-아릴-피리미딘, 이의 제조방법 및 이를 함유하는 약제학적 제제 - Google Patents

치환된 4-아미노-2-아릴-피리미딘, 이의 제조방법 및 이를 함유하는 약제학적 제제 Download PDF

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KR100971093B1
KR100971093B1 KR1020017001840A KR20017001840A KR100971093B1 KR 100971093 B1 KR100971093 B1 KR 100971093B1 KR 1020017001840 A KR1020017001840 A KR 1020017001840A KR 20017001840 A KR20017001840 A KR 20017001840A KR 100971093 B1 KR100971093 B1 KR 100971093B1
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alkyl
group
amino
substituted
isopropyl
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KR20010072439A (ko
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쉰들러우르줄라
쉐나핑거카를
슈트로벨하르트무트
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사노피-아벤티스 도이칠란트 게엠베하
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KR1020017001840A 1998-08-13 1999-08-04 치환된 4-아미노-2-아릴-피리미딘, 이의 제조방법 및 이를 함유하는 약제학적 제제 Expired - Fee Related KR100971093B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19836697.3 1998-08-13
DE19836697A DE19836697A1 (de) 1998-08-13 1998-08-13 Substituierte 4-Amino-2-aryl-pyrimidine, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate

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Publication Number Publication Date
KR20010072439A KR20010072439A (ko) 2001-07-31
KR100971093B1 true KR100971093B1 (ko) 2010-07-20

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KR1020017001840A Expired - Fee Related KR100971093B1 (ko) 1998-08-13 1999-08-04 치환된 4-아미노-2-아릴-피리미딘, 이의 제조방법 및 이를 함유하는 약제학적 제제

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US (1) US6844347B1 (https=)
EP (1) EP1112266B1 (https=)
JP (1) JP4594526B2 (https=)
KR (1) KR100971093B1 (https=)
AR (1) AR020165A1 (https=)
AT (1) ATE240315T1 (https=)
AU (1) AU760988B2 (https=)
BR (1) BR9913003B1 (https=)
CA (1) CA2340405C (https=)
DE (2) DE19836697A1 (https=)
DK (1) DK1112266T3 (https=)
ES (1) ES2196849T3 (https=)
PT (1) PT1112266E (https=)
WO (1) WO2000009496A1 (https=)

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DE19904710A1 (de) 1999-02-05 2000-08-10 Aventis Pharma Gmbh Substituierte 4-Amino-2-aryl-tetrahydrochinazoline, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
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DE60204509T2 (de) * 2001-04-20 2006-03-16 Ciba Speciality Chemicals Holding Inc. 4-Amino-2-(2-pyridinyl)pyrimidine als mikrobizide Wirksubstanzen
AU2003214110A1 (en) 2002-03-15 2003-09-29 Ciba Specialty Chemicals Holding Inc. 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces
US7015227B2 (en) 2002-06-21 2006-03-21 Cgi Pharmaceuticals, Inc. Certain amino-substituted monocycles as kinase modulators
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CA2531619A1 (en) * 2003-07-16 2005-01-27 Neurogen Corporation Biaryl piperazinyl-pyridine analogues
GB0323137D0 (en) * 2003-10-03 2003-11-05 Chang Lisa C W 2,4,6- Trisubstituted pyrimidines and their different uses
JP2007514003A (ja) * 2003-12-15 2007-05-31 アルミラル プロデスファルマ アーゲー アデノシン受容体アンタゴニストとしての２，６−ビスヘテロアリール−４−アミノピリミジン
GB0415365D0 (en) * 2004-07-09 2004-08-11 Astrazeneca Ab Pyrimidine derivatives
GB0415364D0 (en) * 2004-07-09 2004-08-11 Astrazeneca Ab Pyrimidine derivatives
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MY145822A (en) 2004-08-13 2012-04-30 Neurogen Corp Substituted biaryl piperazinyl-pyridine analogues
US20080275064A1 (en) * 2005-04-11 2008-11-06 Deborah Slee Substituted Pyrimidines as Adenosine Receptor Antagonists
US7858786B2 (en) * 2005-05-04 2010-12-28 Vertex Pharmaceuticals Incoropated Pyrimidines and pyrazines useful as modulators of ion channels
CN101679371A (zh) * 2006-12-04 2010-03-24 艾美罗股份公司 作为腺苷受体拮抗剂的取代的嘧啶
JP2010522214A (ja) * 2007-03-21 2010-07-01 アルミラル， エセ．アー． アデノシンレセプターアンタゴニストとしての置換ピリミジン
JP5676249B2 (ja) * 2007-04-20 2015-02-25 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのアミノピリジン誘導体
WO2009068652A1 (en) * 2007-11-30 2009-06-04 Smithkline Beecham Corporation 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators
AU2009322836B2 (en) * 2008-11-25 2013-04-04 Merck Sharp & Dohme Corp. Soluble guanylate cyclase activators
US9284301B2 (en) 2010-03-25 2016-03-15 Merck Sharp & Dohme Corp. Soluble guanylate cyclase activators
UA107112C2 (uk) 2010-05-27 2014-11-25 Мерк Шарп Енд Доме Корп. Активатори розчинної гуанілатциклази
JP6378171B2 (ja) 2012-04-24 2018-08-22 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ｄｎａ−ｐｋ阻害剤
SI3527563T1 (sl) 2013-03-12 2022-01-31 Vertex Pharmaceuticals Incorporated Inhibitorji DNA-PK
RU2675270C2 (ru) 2013-10-17 2018-12-18 Вертекс Фармасьютикалз Инкорпорейтед Сокристаллы и содержащие их фармацевтические композиции
RU2758669C2 (ru) 2016-09-27 2021-11-01 Вертекс Фармасьютикалз Инкорпорейтед Способ лечения рака с применением сочетания днк-поражающих агентов и ингибиторов днк-пк
EP4011873A1 (en) 2020-12-10 2022-06-15 Bayer Aktiengesellschaft Substituted pyrazolo piperidine carboxylic acids

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JP4594526B2 (ja) 2010-12-08
ES2196849T3 (es) 2003-12-16
DE59905572D1 (de) 2003-06-18
EP1112266B1 (de) 2003-05-14
AU760988B2 (en) 2003-05-29
BR9913003A (pt) 2001-05-08
BR9913003B1 (pt) 2014-12-02
CA2340405C (en) 2009-03-17
DK1112266T3 (da) 2003-09-15
ATE240315T1 (de) 2003-05-15
DE19836697A1 (de) 2000-02-17
AR020165A1 (es) 2002-04-10
PT1112266E (pt) 2003-09-30
US6844347B1 (en) 2005-01-18
CA2340405A1 (en) 2000-02-24
KR20010072439A (ko) 2001-07-31
AU5730799A (en) 2000-03-06
JP2002522536A (ja) 2002-07-23
EP1112266A1 (de) 2001-07-04

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