KR100960597B1 - 레보시멘단의 조절 방출성 경구 조성물 - Google Patents

레보시멘단의 조절 방출성 경구 조성물 Download PDF

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Publication number
KR100960597B1
KR100960597B1 KR1020007011788A KR20007011788A KR100960597B1 KR 100960597 B1 KR100960597 B1 KR 100960597B1 KR 1020007011788 A KR1020007011788 A KR 1020007011788A KR 20007011788 A KR20007011788 A KR 20007011788A KR 100960597 B1 KR100960597 B1 KR 100960597B1
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South Korea
Prior art keywords
composition
release
controlled release
pyridazinyl
tetrahydro
Prior art date
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Expired - Fee Related
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KR1020007011788A
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English (en)
Korean (ko)
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KR20010071172A (ko
Inventor
라르마일카
하르줄라마아리트
안틸라사일리
레흐토넨라쎄
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오리온 코포레이션
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8551575&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100960597(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 오리온 코포레이션 filed Critical 오리온 코포레이션
Publication of KR20010071172A publication Critical patent/KR20010071172A/ko
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Publication of KR100960597B1 publication Critical patent/KR100960597B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
KR1020007011788A 1998-04-23 1999-04-23 레보시멘단의 조절 방출성 경구 조성물 Expired - Fee Related KR100960597B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI980901A FI980901A7 (fi) 1998-04-23 1998-04-23 Levosimendaania säädellysti vapauttavia oraalisia koostumuksia
FI980901 1998-04-23
PCT/FI1999/000329 WO1999055305A2 (en) 1998-04-23 1999-04-23 Controlled release peroral compositions of levosimendan

Publications (2)

Publication Number Publication Date
KR20010071172A KR20010071172A (ko) 2001-07-28
KR100960597B1 true KR100960597B1 (ko) 2010-06-07

Family

ID=8551575

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007011788A Expired - Fee Related KR100960597B1 (ko) 1998-04-23 1999-04-23 레보시멘단의 조절 방출성 경구 조성물

Country Status (37)

Country Link
US (1) US7045147B1 (https=)
EP (1) EP1071397B1 (https=)
JP (2) JP4566402B2 (https=)
KR (1) KR100960597B1 (https=)
CN (1) CN1248691C (https=)
AR (1) AR019096A1 (https=)
AT (1) ATE258425T1 (https=)
AU (1) AU756641B2 (https=)
BG (1) BG64839B1 (https=)
BR (1) BR9909869A (https=)
CA (1) CA2329234C (https=)
CO (1) CO5070607A1 (https=)
CZ (1) CZ295194B6 (https=)
DE (1) DE69914472T2 (https=)
DK (1) DK1071397T3 (https=)
EA (1) EA002829B1 (https=)
EE (1) EE04220B1 (https=)
ES (1) ES2215379T3 (https=)
FI (1) FI980901A7 (https=)
GE (1) GEP20032906B (https=)
HR (1) HRP20000704B1 (https=)
HU (1) HUP0101458A3 (https=)
ID (1) ID27987A (https=)
IL (2) IL138951A0 (https=)
MX (1) MXPA00010367A (https=)
NO (1) NO329809B1 (https=)
NZ (1) NZ507453A (https=)
PL (1) PL197447B1 (https=)
PT (1) PT1071397E (https=)
RS (1) RS49962B (https=)
SI (1) SI1071397T1 (https=)
SK (1) SK285427B6 (https=)
TR (1) TR200003102T2 (https=)
TW (1) TWI224507B (https=)
UA (1) UA68376C2 (https=)
WO (1) WO1999055305A2 (https=)
ZA (1) ZA200005632B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20011465A0 (fi) * 2001-07-04 2001-07-04 Orion Corp Pyridatsinonijohdannaisen uusi käyttö
WO2004082615A2 (en) * 2003-03-14 2004-09-30 Nirmal Mulye A process for preparing sustained release tablets
FI20070521L (fi) * 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
MX337213B (es) 2008-06-30 2016-02-17 Tocagen Inc Formulaciones de 5-fluorocitosina y usos de las mismas.
JP2014172850A (ja) * 2013-03-07 2014-09-22 Capsugel Belgium Nv ハードカプセル製剤
CN105784895B (zh) * 2015-10-30 2018-05-22 成都欣捷高新技术开发有限公司 一种用高效液相色谱仪检测左西孟旦中杂质的方法
WO2021126884A1 (en) 2019-12-16 2021-06-24 Tenax Therapeutics, Inc. LEVOSIMENDAN FOR TREATING PULMONARY HYPERTENSION WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION (PH-HF-pEF)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383449A2 (en) * 1989-02-11 1990-08-22 Orion-Yhtymà„ Oy Pyridazinone derivatives and processes for preparing the same
WO1992012135A1 (en) * 1991-01-03 1992-07-23 Orion-Yhtymä Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-hydrazono]propanedinitrile

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU555304B2 (en) 1982-04-05 1986-09-18 Merck Sharp & Dohme Limited Stabilization of drugs in alginic acid and magnesium hydroxide granules
US4716042A (en) 1986-06-16 1987-12-29 American Home Products Corporation Stabilized coated aspirin tablets
US5213811A (en) * 1991-09-13 1993-05-25 Sterling Drug Inc. Oral sustained-release drug compositions
GB2266841A (en) 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
FI973804A7 (fi) 1997-09-26 1999-03-27 Orion Yhtymae Oy Levosimendaanin oraalisia koostumuksia
FI974578L (fi) * 1997-12-19 1999-06-20 Orion Yhtymae Oyj Menetelmä levosimendaanin antamiseksi
FI980902A7 (fi) * 1998-04-23 1999-10-24 Orion Yhtymae Oyj Levosimendaanin stabiileja koostumuksia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383449A2 (en) * 1989-02-11 1990-08-22 Orion-Yhtymà„ Oy Pyridazinone derivatives and processes for preparing the same
WO1992012135A1 (en) * 1991-01-03 1992-07-23 Orion-Yhtymä Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-hydrazono]propanedinitrile

Also Published As

Publication number Publication date
EE200000617A (et) 2002-06-17
HK1034032A1 (en) 2001-10-12
FI980901A7 (fi) 1999-10-24
ID27987A (id) 2001-05-03
EE04220B1 (et) 2004-02-16
CZ20003780A3 (en) 2001-05-16
KR20010071172A (ko) 2001-07-28
JP2010083900A (ja) 2010-04-15
TWI224507B (en) 2004-12-01
HRP20000704B1 (hr) 2009-11-30
ES2215379T3 (es) 2004-10-01
MXPA00010367A (es) 2002-06-04
HUP0101458A2 (hu) 2002-03-28
HUP0101458A3 (en) 2002-05-28
AR019096A1 (es) 2001-12-26
YU63900A (sh) 2003-07-07
NO20005313L (no) 2000-11-21
AU3524699A (en) 1999-11-16
RS49962B (sr) 2008-09-29
SK285427B6 (sk) 2007-01-04
CA2329234C (en) 2008-06-10
PT1071397E (pt) 2004-06-30
JP4566402B2 (ja) 2010-10-20
NO329809B1 (no) 2010-12-20
UA68376C2 (en) 2004-08-16
DE69914472T2 (de) 2004-11-11
DK1071397T3 (da) 2004-04-05
EA002829B1 (ru) 2002-10-31
BG64839B1 (bg) 2006-06-30
EP1071397A2 (en) 2001-01-31
EA200001098A1 (ru) 2001-04-23
DE69914472D1 (de) 2004-03-04
WO1999055305A2 (en) 1999-11-04
WO1999055305A3 (en) 1999-12-29
JP2002512946A (ja) 2002-05-08
ATE258425T1 (de) 2004-02-15
EP1071397B1 (en) 2004-01-28
GEP20032906B (en) 2003-02-25
BR9909869A (pt) 2000-12-19
NO20005313D0 (no) 2000-10-20
TR200003102T2 (tr) 2001-02-21
CO5070607A1 (es) 2001-08-28
SK15542000A3 (sk) 2001-08-06
CZ295194B6 (cs) 2005-06-15
CN1248691C (zh) 2006-04-05
PL197447B1 (pl) 2008-03-31
HRP20000704A2 (en) 2001-04-30
CA2329234A1 (en) 1999-11-04
US7045147B1 (en) 2006-05-16
IL138951A0 (en) 2001-11-25
BG104959A (en) 2001-07-31
PL344078A1 (en) 2001-09-24
NZ507453A (en) 2003-02-28
CN1301163A (zh) 2001-06-27
AU756641B2 (en) 2003-01-16
ZA200005632B (en) 2002-01-14
SI1071397T1 (en) 2004-06-30
FI980901A0 (fi) 1998-04-23
IL138951A (en) 2006-10-31

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