KR100894852B1 - 지질-폴리머-접합체 조성물 - Google Patents

지질-폴리머-접합체 조성물 Download PDF

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Publication number
KR100894852B1
KR100894852B1 KR1020037015722A KR20037015722A KR100894852B1 KR 100894852 B1 KR100894852 B1 KR 100894852B1 KR 1020037015722 A KR1020037015722 A KR 1020037015722A KR 20037015722 A KR20037015722 A KR 20037015722A KR 100894852 B1 KR100894852 B1 KR 100894852B1
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South Korea
Prior art keywords
polymer
poly
composition
lipid
dodasuc
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Expired - Fee Related
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KR1020037015722A
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English (en)
Korean (ko)
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KR20040027513A (ko
Inventor
메트세라아르조스베르트마아르텐
헨닌크윌헬무스에베라르두스
드브링거톰
드보에르레오나르두스윌헬무스테오도루스
오우쏘렌크리스티엔
스톰게리트
브루인피터
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아스텔라스 파마 유럽 비.브이.
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Publication of KR20040027513A publication Critical patent/KR20040027513A/ko
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Polyamides (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
KR1020037015722A 2001-06-01 2002-06-03 지질-폴리머-접합체 조성물 Expired - Fee Related KR100894852B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01202107 2001-06-01
EP01202107.7 2001-06-01
PCT/EP2002/006783 WO2002098952A1 (en) 2001-06-01 2002-06-03 Lipid-polymer-conjugates compositions

Publications (2)

Publication Number Publication Date
KR20040027513A KR20040027513A (ko) 2004-04-01
KR100894852B1 true KR100894852B1 (ko) 2009-04-24

Family

ID=8180408

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020037015722A Expired - Fee Related KR100894852B1 (ko) 2001-06-01 2002-06-03 지질-폴리머-접합체 조성물
KR1020037015720A Expired - Fee Related KR100874847B1 (ko) 2001-06-01 2002-06-03 지질-폴리머-접합체

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020037015720A Expired - Fee Related KR100874847B1 (ko) 2001-06-01 2002-06-03 지질-폴리머-접합체

Country Status (20)

Country Link
US (3) US20040241222A1 (https=)
EP (2) EP1392755B1 (https=)
JP (2) JP2004527586A (https=)
KR (2) KR100894852B1 (https=)
CN (2) CN1271116C (https=)
AT (2) ATE416214T1 (https=)
BR (2) BR0209695A (https=)
CA (2) CA2448856A1 (https=)
CZ (2) CZ20033480A3 (https=)
DE (2) DE60218154T2 (https=)
EE (2) EE200300596A (https=)
ES (2) ES2318027T3 (https=)
HR (2) HRP20030976A2 (https=)
HU (2) HUP0400171A2 (https=)
MX (2) MXPA03011049A (https=)
NO (2) NO20035263D0 (https=)
PL (2) PL369455A1 (https=)
SK (2) SK15972003A3 (https=)
WO (2) WO2002098952A1 (https=)
ZA (2) ZA200308938B (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100894852B1 (ko) * 2001-06-01 2009-04-24 아스텔라스 파마 유럽 비.브이. 지질-폴리머-접합체 조성물
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
EP1393720A1 (en) * 2002-08-27 2004-03-03 Universiteit Utrecht Vesicle-encapsulated corticosteroids for treatment of cancer
SG113442A1 (en) * 2002-11-29 2005-08-29 Agency Science Tech & Res Improved temperature sensitive micelles
FR2855521B1 (fr) 2003-05-28 2005-08-05 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.
EP1481683A1 (en) * 2003-05-30 2004-12-01 Yamanouchi Pharmaceutical Co. Ltd. P-selectin targeting ligand and compositions thereof
SE527505C2 (sv) * 2003-06-10 2006-03-28 Anna Imberg Komposita material och partiklar
FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
JP5331967B2 (ja) * 2006-05-09 2013-10-30 国立大学法人大阪大学 コレステロールアミン導入ポリ−γ−グルタミン酸誘導体
JP4936312B2 (ja) 2006-07-20 2012-05-23 株式会社島津製作所 新規な両親媒性物質、それを用いた薬剤搬送システム及び分子イメージングシステム
JP5258189B2 (ja) * 2006-11-09 2013-08-07 学校法人 関西大学 柔軟性生分解性ポリマー
ITRM20070327A1 (it) * 2007-06-11 2008-12-12 Univ Palermo Vettori colloidali a struttura poliamminoacidica per il rilascio orale di peptidi e proteine e relativo metodo di produzione.
WO2009131672A1 (en) * 2008-04-22 2009-10-29 University Of Massachusetts Stabilized liposome compositions and related methods of use
KR101695836B1 (ko) * 2010-04-13 2017-01-16 (주)아모레퍼시픽 경피흡수용 고분자-리포좀 나노복합체 조성물 및 그 제조방법
ES2385995B2 (es) * 2011-01-10 2013-05-21 Universidade De Santiago De Compostela Nanocápsulas con cubierta polimérica
US9993427B2 (en) * 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
WO2019172362A1 (ja) * 2018-03-07 2019-09-12 公益財団法人川崎市産業振興財団 刺激応答性ポリマー
JPWO2023282296A1 (https=) * 2021-07-07 2023-01-12
CN121175037A (zh) * 2023-05-11 2025-12-19 新加坡科技研究局 用于制备包封试剂的脂质纳米颗粒的化合物、包含所述化合物的纳米颗粒组合物及其相关方法
CN121487757A (zh) 2023-07-27 2026-02-06 博莱科瑞士股份有限公司 含有脂质-聚氨基酸缀合物的超声响应性囊泡
WO2025031991A1 (en) * 2023-08-04 2025-02-13 Polypeptide Therapeutic Solutions, S.L. Stealth-stabilized sulfur-containing lipo/polyamino acids
WO2025080209A1 (en) * 2023-10-10 2025-04-17 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound and related methods thereof
WO2025090023A1 (en) * 2023-10-24 2025-05-01 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound, and related methods thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994020073A1 (en) * 1993-03-03 1994-09-15 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0657722B2 (ja) * 1986-05-27 1994-08-03 三菱化成株式会社 水溶性ポリマ−組成物
US5149794A (en) * 1990-11-01 1992-09-22 State Of Oregon Covalent lipid-drug conjugates for drug targeting
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
US5972379A (en) * 1995-02-14 1999-10-26 Sequus Pharmaceuticals, Inc. Liposome composition and method for administering a quinolone
US6197332B1 (en) * 1997-08-13 2001-03-06 Chiron Corporation Lipid-conjugated polyamide compounds and related compositions and methods thereof
GB9811059D0 (en) * 1998-05-23 1998-07-22 Univ Strathclyde Polyamino acid vesicles
KR100894852B1 (ko) * 2001-06-01 2009-04-24 아스텔라스 파마 유럽 비.브이. 지질-폴리머-접합체 조성물

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994020073A1 (en) * 1993-03-03 1994-09-15 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes

Also Published As

Publication number Publication date
US20100145018A1 (en) 2010-06-10
CZ20033480A3 (cs) 2004-07-14
BR0209699A (pt) 2005-02-01
ES2282439T3 (es) 2007-10-16
SK15972003A3 (sk) 2004-06-08
ZA200308937B (en) 2004-11-17
JP2004527586A (ja) 2004-09-09
DE60230137D1 (de) 2009-01-15
DE60218154T2 (de) 2007-10-31
BR0209695A (pt) 2005-01-11
CZ20033479A3 (cs) 2004-07-14
HRP20030975A2 (en) 2005-08-31
CN1271116C (zh) 2006-08-23
EE200300598A (et) 2004-02-16
MXPA03011050A (es) 2004-06-25
ATE416214T1 (de) 2008-12-15
EP1392756A2 (en) 2004-03-03
EP1392755A1 (en) 2004-03-03
NO20035264D0 (no) 2003-11-27
WO2002098951A3 (en) 2003-02-20
JP2004527585A (ja) 2004-09-09
HUP0400174A2 (en) 2007-02-28
NO20035263D0 (no) 2003-11-27
ATE353927T1 (de) 2007-03-15
EP1392755B1 (en) 2008-12-03
KR100874847B1 (ko) 2008-12-19
CA2448858A1 (en) 2002-12-12
US20040254352A1 (en) 2004-12-16
WO2002098951A2 (en) 2002-12-12
PL369455A1 (en) 2005-04-18
KR20040027512A (ko) 2004-04-01
US20040241222A1 (en) 2004-12-02
WO2002098952A1 (en) 2002-12-12
CN1308375C (zh) 2007-04-04
CN1520435A (zh) 2004-08-11
CN1602326A (zh) 2005-03-30
MXPA03011049A (es) 2004-06-25
HUP0400171A2 (en) 2007-02-28
EE200300596A (et) 2004-02-16
ZA200308938B (en) 2004-11-17
SK15982003A3 (sk) 2004-06-08
PL367479A1 (en) 2005-02-21
ES2318027T3 (es) 2009-05-01
CA2448856A1 (en) 2002-12-12
KR20040027513A (ko) 2004-04-01
DE60218154D1 (de) 2007-03-29
HRP20030976A2 (en) 2005-08-31
EP1392756B1 (en) 2007-02-14

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