KR100858857B1 - 항원특이적 세포상해성 ｔ 세포 확대배양방법 - Google Patents

항원특이적 세포상해성 ｔ 세포 확대배양방법 Download PDF

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KR100858857B1
KR100858857B1 KR1020047002212A KR20047002212A KR100858857B1 KR 100858857 B1 KR100858857 B1 KR 100858857B1 KR 1020047002212 A KR1020047002212 A KR 1020047002212A KR 20047002212 A KR20047002212 A KR 20047002212A KR 100858857 B1 KR100858857 B1 KR 100858857B1
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KR20040030093A (ko
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히로아끼 사가와
미쯔꼬 이데노
이꾸노신 가또
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다카라 바이오 가부시키가이샤
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4267—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/90—Polysaccharides
    • C12N2501/905—Hyaluronic acid
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    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020047002212A 2001-08-15 2002-08-15 항원특이적 세포상해성 ｔ 세포 확대배양방법 Expired - Fee Related KR100858857B1 (ko)

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Application Number Priority Date Filing Date Title
JPJP-P-2001-00246747 2001-08-15
JP2001246747 2001-08-15
JPJP-P-2001-00376966 2001-12-11
JP2001376966 2001-12-11
JP2002084428 2002-03-25
JPJP-P-2002-00084428 2002-03-25
PCT/JP2002/008298 WO2003016511A1 (fr) 2001-08-15 2002-08-15 Procede permettant une culture etendue de lymphocytes t cytotoxiques specifiques d'un antigene

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KR1020077028426A Division KR100888915B1 (ko) 2001-08-15 2002-08-15 항원특이적 세포상해성 ｔ 세포 확대배양방법

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KR20040030093A KR20040030093A (ko) 2004-04-08
KR100858857B1 true KR100858857B1 (ko) 2008-09-17

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KR1020047002212A Expired - Fee Related KR100858857B1 (ko) 2001-08-15 2002-08-15 항원특이적 세포상해성 ｔ 세포 확대배양방법
KR1020077028426A Expired - Fee Related KR100888915B1 (ko) 2001-08-15 2002-08-15 항원특이적 세포상해성 ｔ 세포 확대배양방법

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US (1) US7910368B2 (https=)
EP (2) EP1424387B1 (https=)
JP (3) JP4949607B2 (https=)
KR (2) KR100858857B1 (https=)
CN (2) CN100510060C (https=)
AT (1) ATE429486T1 (https=)
DE (1) DE60232083D1 (https=)
TW (3) TWI315740B (https=)
WO (1) WO2003016511A1 (https=)

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TWI315740B (https=) 2001-08-15 2009-10-11 Takara Bio Inc
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CN1839202B (zh) * 2003-08-22 2012-07-18 宝生物工程株式会社 细胞毒性淋巴细胞的制备方法
EP1916302A4 (en) 2005-08-17 2009-10-21 Takara Bio Inc PROCESS FOR THE PRODUCTION OF LYMPHOCYTES
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CN102046780A (zh) 2008-03-27 2011-05-04 宝生物工程株式会社 转染的细胞的生产方法
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WO2011024791A1 (ja) 2009-08-25 2011-03-03 タカラバイオ株式会社 レチノイン酸存在下でのｔ細胞集団の製造方法
KR101110866B1 (ko) * 2009-12-29 2012-02-20 재단법인 포항산업과학연구원 몰드 동판 가공 장치
JP5805089B2 (ja) * 2010-08-10 2015-11-04 タカラバイオ株式会社 細胞集団の製造方法
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CN103013914B (zh) * 2012-12-13 2014-12-03 吉林省拓华生物科技有限公司 体外培养杀伤性t细胞的方法
US20150079626A1 (en) * 2013-03-19 2015-03-19 Lsip, Llc Method of obtaining a cell population containing cancer stem cells
AU2015259877B2 (en) 2014-05-15 2021-02-25 National University Of Singapore Modified natural killer cells and uses thereof
KR102660336B1 (ko) 2017-03-27 2024-04-26 내셔널 유니버시티 오브 싱가포르 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도
MX2019011570A (es) 2017-03-27 2019-11-18 Nat Univ Singapore Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
AU2019219454A1 (en) 2018-02-09 2020-08-27 National University Of Singapore Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
CN112055717B (zh) 2018-04-02 2024-04-26 新加坡国立大学 用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子
PT3835415T (pt) * 2018-08-10 2024-12-18 Univ Kyoto Método para produção de células positivas para cd3
EP3844186A4 (en) 2018-08-29 2022-08-17 National University of Singapore METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
US12590148B2 (en) 2018-11-26 2026-03-31 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy

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ATE429486T1 (de) 2009-05-15
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