KR100857898B1 - 이식된 장기의 거부반응의 치료와 예방에 사용되는(ｒ)-이부프로펜 메탄설폰아마이드 및 이의 염 - Google Patents

이식된 장기의 거부반응의 치료와 예방에 사용되는(ｒ)-이부프로펜 메탄설폰아마이드 및 이의 염 Download PDF

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KR100857898B1
KR100857898B1 KR1020037009714A KR20037009714A KR100857898B1 KR 100857898 B1 KR100857898 B1 KR 100857898B1 KR 1020037009714 A KR1020037009714 A KR 1020037009714A KR 20037009714 A KR20037009714 A KR 20037009714A KR 100857898 B1 KR100857898 B1 KR 100857898B1
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South Korea
Prior art keywords
kidney
ischemia
transplanted
rejection
transplantation
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Korean (ko)
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KR20030074725A (ko
Inventor
리카르도 베르티니
프란세스코 콜로타
로베르토 노벨리니
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돔페 파르마 에스.피.에이.
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Assigned to 돔페 파르마써티씨 에스.피.에이. reassignment 돔페 파르마써티씨 에스.피.에이. 권리의 전부이전등록 Assignors: 돔페 파르마 에스.피.에이.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
KR1020037009714A 2001-02-02 2002-01-30 이식된 장기의 거부반응의 치료와 예방에 사용되는(ｒ)-이부프로펜 메탄설폰아마이드 및 이의 염 Expired - Fee Related KR100857898B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2001A000206 2001-02-02
IT2001MI000206A ITMI20010206A1 (it) 2001-02-02 2001-02-02 Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz
PCT/EP2002/000946 WO2002062330A2 (en) 2001-02-02 2002-01-30 Use of (r)-ibuprofen methanesulfonamide and salts thereof in the treatment and prevention of rejection reactions of transplanted organs

Publications (2)

Publication Number Publication Date
KR20030074725A KR20030074725A (ko) 2003-09-19
KR100857898B1 true KR100857898B1 (ko) 2008-09-10

Family

ID=11446717

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037009714A Expired - Fee Related KR100857898B1 (ko) 2001-02-02 2002-01-30 이식된 장기의 거부반응의 치료와 예방에 사용되는(ｒ)-이부프로펜 메탄설폰아마이드 및 이의 염

Country Status (26)

Country Link
US (1) US7560487B2 (https=)
EP (1) EP1355641B1 (https=)
JP (1) JP2004517948A (https=)
KR (1) KR100857898B1 (https=)
CN (1) CN1561205A (https=)
AT (1) ATE304846T1 (https=)
AU (1) AU2002250869B2 (https=)
BR (2) BR0206804A (https=)
CA (1) CA2432432C (https=)
CZ (1) CZ303665B6 (https=)
DE (1) DE60206245T2 (https=)
DK (1) DK1355641T3 (https=)
EE (1) EE05233B1 (https=)
ES (1) ES2248541T3 (https=)
HU (1) HU229070B1 (https=)
IL (1) IL157180A (https=)
IT (1) ITMI20010206A1 (https=)
MX (1) MXPA03006686A (https=)
NO (1) NO334285B1 (https=)
NZ (1) NZ526655A (https=)
PL (1) PL215109B1 (https=)
PT (1) PT1355641E (https=)
RU (1) RU2257895C2 (https=)
SK (1) SK287632B6 (https=)
WO (1) WO2002062330A2 (https=)
ZA (1) ZA200304861B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1579859E (pt) * 2004-03-25 2007-03-30 Dompe Pha R Ma Spa Res & Mfg Utilização de n-(2-aril-propionil)-sulfonamidas pata o tratamento de lesões da medula espinal
EP1883405A4 (en) 2005-05-09 2010-01-27 Takeda Pharmaceuticals North A METHODS OF TREATING NEPHROLITHIASIS
KR20150024919A (ko) * 2006-11-13 2015-03-09 다케다 파마슈티칼스 유에스에이, 인코포레이티드 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법
EP2308484A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
EP2308485A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
CA2812034C (en) 2010-09-10 2018-10-23 Takeda Pharmaceuticals U.S.A., Inc. Methods for concomitant treatment of theophylline and febuxostat
US10046002B2 (en) 2013-08-02 2018-08-14 Syntrix Biosystems Inc. Method for treating cancer using chemokine antagonists
US10561676B2 (en) * 2013-08-02 2020-02-18 Syntrix Biosystems Inc. Method for treating cancer using dual antagonists of CXCR1 and CXCR2
US20200003787A1 (en) * 2017-03-15 2020-01-02 Numares Ag Method for Using a Marker Set for Determining the Risk of Kidney Rejection

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024710A1 (en) * 1998-10-23 2000-05-04 Dompe' S.P.A. N-(2-aryl-propionyl)-sulfonamides and pharmaceutical preparations containing them

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879283A (en) * 1985-10-03 1989-11-07 Wisconsin Alumni Research Foundation Solution for the preservation of organs
RU2008901C1 (ru) * 1991-03-29 1994-03-15 Донецкий государственный медицинский институт им.М.Горького Способ фармакологической защиты децентрализованной почки
RU2126262C1 (ru) * 1992-09-17 1999-02-20 Амген Боулдер Инк. Фармацевтическая композиция
IL110296A (en) * 1993-07-16 1999-12-31 Smithkline Beecham Corp Imidazole compounds process for their preparation and pharmaceutical compositions containing them
JPH08231413A (ja) * 1994-12-29 1996-09-10 Mochida Pharmaceut Co Ltd 臓器障害に基づく疾患の予防・治療剤
US6355682B1 (en) * 2001-05-11 2002-03-12 Assa Weinberg Treatment of acute renal failure by administration of N-acetylcysteine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024710A1 (en) * 1998-10-23 2000-05-04 Dompe' S.P.A. N-(2-aryl-propionyl)-sulfonamides and pharmaceutical preparations containing them

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
논문 Transplantation Pro. (2000)*

Also Published As

Publication number Publication date
EE200300340A (et) 2003-10-15
WO2002062330A2 (en) 2002-08-15
CA2432432A1 (en) 2002-08-15
DE60206245D1 (de) 2006-02-02
NO20033273D0 (no) 2003-07-18
DK1355641T3 (da) 2005-10-17
RU2257895C2 (ru) 2005-08-10
NO20033273L (no) 2003-07-18
KR20030074725A (ko) 2003-09-19
BRPI0206804B1 (pt) 2018-09-25
US7560487B2 (en) 2009-07-14
ZA200304861B (en) 2004-06-30
CZ303665B6 (cs) 2013-02-20
MXPA03006686A (es) 2004-05-31
WO2002062330A3 (en) 2003-04-03
PT1355641E (pt) 2005-11-30
ES2248541T3 (es) 2006-03-16
AU2002250869B2 (en) 2006-10-19
ITMI20010206A1 (it) 2002-08-02
NZ526655A (en) 2005-02-25
HUP0303024A2 (hu) 2003-12-29
NO334285B1 (no) 2014-01-27
ATE304846T1 (de) 2005-10-15
EP1355641B1 (en) 2005-09-21
CA2432432C (en) 2008-03-25
DE60206245T2 (de) 2006-06-14
HUP0303024A3 (en) 2005-07-28
SK287632B6 (sk) 2011-04-05
PL215109B1 (pl) 2013-10-31
JP2004517948A (ja) 2004-06-17
EE05233B1 (et) 2009-12-15
PL363576A1 (en) 2004-11-29
CN1561205A (zh) 2005-01-05
RU2003126600A (ru) 2005-02-27
SK9732003A3 (en) 2003-11-04
BR0206804A (pt) 2004-02-03
EP1355641A2 (en) 2003-10-29
HU229070B1 (hu) 2013-07-29
IL157180A (en) 2009-06-15
CZ20032095A3 (en) 2004-05-12
US20040102520A1 (en) 2004-05-27

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