KR100780538B1 - 키랄 2-히드록시메틸-1,4-벤조디옥산 화합물의 제조방법 - Google Patents

키랄 2-히드록시메틸-1,4-벤조디옥산 화합물의 제조방법 Download PDF

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Publication number
KR100780538B1
KR100780538B1 KR1020060072945A KR20060072945A KR100780538B1 KR 100780538 B1 KR100780538 B1 KR 100780538B1 KR 1020060072945 A KR1020060072945 A KR 1020060072945A KR 20060072945 A KR20060072945 A KR 20060072945A KR 100780538 B1 KR100780538 B1 KR 100780538B1
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KR
South Korea
Prior art keywords
hydroxymethyl
chiral
benzodioxane
compound
group
Prior art date
Application number
KR1020060072945A
Other languages
English (en)
Korean (ko)
Inventor
어진
원덕권
문병헌
권오준
정창우
진경용
전용국
강현빈
김성진
Original Assignee
안국약품 주식회사
주식회사 알에스텍
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 안국약품 주식회사, 주식회사 알에스텍 filed Critical 안국약품 주식회사
Priority to KR1020060072945A priority Critical patent/KR100780538B1/ko
Priority to PCT/KR2006/003458 priority patent/WO2008016199A1/fr
Priority to CN2006800555155A priority patent/CN101501016B/zh
Application granted granted Critical
Publication of KR100780538B1 publication Critical patent/KR100780538B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
KR1020060072945A 2006-08-02 2006-08-02 키랄 2-히드록시메틸-1,4-벤조디옥산 화합물의 제조방법 KR100780538B1 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020060072945A KR100780538B1 (ko) 2006-08-02 2006-08-02 키랄 2-히드록시메틸-1,4-벤조디옥산 화합물의 제조방법
PCT/KR2006/003458 WO2008016199A1 (fr) 2006-08-02 2006-08-31 Procédé de préparation d'un composé chiral de 2-hydroxyméthyl-1,4-benzodioxane
CN2006800555155A CN101501016B (zh) 2006-08-02 2006-08-31 手性2-羟甲基-1,4-苯并二噁烷化合物的制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020060072945A KR100780538B1 (ko) 2006-08-02 2006-08-02 키랄 2-히드록시메틸-1,4-벤조디옥산 화합물의 제조방법

Publications (1)

Publication Number Publication Date
KR100780538B1 true KR100780538B1 (ko) 2007-11-30

Family

ID=38997362

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020060072945A KR100780538B1 (ko) 2006-08-02 2006-08-02 키랄 2-히드록시메틸-1,4-벤조디옥산 화합물의 제조방법

Country Status (3)

Country Link
KR (1) KR100780538B1 (fr)
CN (1) CN101501016B (fr)
WO (1) WO2008016199A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780650A (en) 1995-03-24 1998-07-14 Daiso Co., Ltd. Process for preparation of 1,4-benzodioxane derivative
KR20000016758A (ko) 1997-05-12 2000-03-25 사또모 고지 1,4-벤조디옥산 유도체의 제조 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU701883B2 (en) * 1996-01-25 1999-02-11 Duphar International Research B.V. Process for the stereoselective preparation of a hetero-bicyclic alcohol enantiomer
US20060167282A1 (en) * 2002-07-29 2006-07-27 Tatsuyoshi Tanaka Process for industrially producing optically active 1,4- benzodioxane derivative

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780650A (en) 1995-03-24 1998-07-14 Daiso Co., Ltd. Process for preparation of 1,4-benzodioxane derivative
KR20000016758A (ko) 1997-05-12 2000-03-25 사또모 고지 1,4-벤조디옥산 유도체의 제조 방법

Also Published As

Publication number Publication date
WO2008016199A1 (fr) 2008-02-07
CN101501016A (zh) 2009-08-05
CN101501016B (zh) 2012-10-24

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