KR100726818B1 - 오일 면역 보강제 백신 - Google Patents

오일 면역 보강제 백신 Download PDF

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Publication number
KR100726818B1
KR100726818B1 KR1020000065477A KR20000065477A KR100726818B1 KR 100726818 B1 KR100726818 B1 KR 100726818B1 KR 1020000065477 A KR1020000065477 A KR 1020000065477A KR 20000065477 A KR20000065477 A KR 20000065477A KR 100726818 B1 KR100726818 B1 KR 100726818B1
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KR
South Korea
Prior art keywords
vaccine
oil
aqueous phase
weight
emulsifier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020000065477A
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English (en)
Korean (ko)
Other versions
KR20010051463A (ko
Inventor
사이토코이치
키시모토요코
미야하라토쿠지
타카세코우조우
Original Assignee
엔오에프 코오포레이션
쥬리디컬 파운데이션 더 케모-세로-쎄라퓨틱 리서치 인스티튜트
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Application filed by 엔오에프 코오포레이션, 쥬리디컬 파운데이션 더 케모-세로-쎄라퓨틱 리서치 인스티튜트 filed Critical 엔오에프 코오포레이션
Publication of KR20010051463A publication Critical patent/KR20010051463A/ko
Application granted granted Critical
Publication of KR100726818B1 publication Critical patent/KR100726818B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020000065477A 1999-11-05 2000-11-06 오일 면역 보강제 백신 Expired - Fee Related KR100726818B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP316121/1999 1999-11-05
JP31612199A JP2001131087A (ja) 1999-11-05 1999-11-05 オイルアジュバントワクチン

Publications (2)

Publication Number Publication Date
KR20010051463A KR20010051463A (ko) 2001-06-25
KR100726818B1 true KR100726818B1 (ko) 2007-06-12

Family

ID=18073491

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020000065477A Expired - Fee Related KR100726818B1 (ko) 1999-11-05 2000-11-06 오일 면역 보강제 백신

Country Status (10)

Country Link
US (1) US20050158330A1 (enExample)
EP (1) EP1097721B1 (enExample)
JP (1) JP2001131087A (enExample)
KR (1) KR100726818B1 (enExample)
CN (1) CN100384473C (enExample)
AU (1) AU780054B2 (enExample)
DE (1) DE60002650T2 (enExample)
DK (1) DK1097721T3 (enExample)
ES (1) ES2199734T3 (enExample)
TW (1) TW581682B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6620976B2 (en) 2001-03-27 2003-09-16 Nof Corporation Polyethylene glycol and process for producing the same
FR2824279B1 (fr) * 2001-05-04 2004-05-28 Seppic Sa Emulsion e/h concentree
US6676958B2 (en) 2001-06-19 2004-01-13 Advanced Bioadjuvants, Llc Adjuvant composition for mucosal and injection delivered vaccines
WO2003000291A1 (fr) * 2001-06-22 2003-01-03 Techno Network Shikoku Co., Ltd. Vesicules lipidiques, processus de production de vesicules lipidiques et procede d'immobilisation de gene sur ces vesicules lipidiques
FR2824269B1 (fr) * 2001-09-03 2012-03-02 Seppic Sa Composition adjuvante constituee de 1% a 15% de tensioactifs a hlb global compris entre 5 et 8 et de 85% a 99% de corps gras
TWI350174B (en) * 2003-03-12 2011-10-11 Wyeth Corp Adjuvanted bovine vaccines
GB2421908A (en) * 2004-12-23 2006-07-12 Univ College London Hospitals Medicament for treatment of inflammatory diseases
CN101111258B (zh) * 2005-01-19 2011-07-06 大日本住友制药株式会社 稀释用乳化组合物及癌疫苗组合物
ES2388684T3 (es) 2005-04-25 2012-10-17 Cadila Pharmaceuticals Limited Adyuvantes de vacunas
EP2172263A4 (en) * 2007-07-02 2015-08-05 Nisshin Oillio Group Ltd E / H / E EMULSION COMPOSITION
US8010465B2 (en) * 2008-02-26 2011-08-30 Microsoft Corporation Predicting candidates using input scopes
CN101721694B (zh) * 2009-11-07 2013-01-30 中国农业科学院兰州兽医研究所 山羊支原体肺炎二联灭活疫苗及其制备方法
IN2014DN05879A (enExample) * 2012-01-31 2015-05-22 Benemilk Ltd
CN102580082B (zh) * 2012-02-28 2014-12-10 肇庆大华农生物药品有限公司 一种禽用灭活疫苗及其制备方法
CN103223164B (zh) * 2013-04-15 2014-08-20 华南农业大学 一种水包油包水型佐剂疫苗及其制备方法
US20150359880A1 (en) * 2014-06-16 2015-12-17 Biomune Company Dual adjuvant vaccine compositions, preparation and uses
CN104398478B (zh) * 2014-11-03 2017-05-10 江苏省农业科学院 兽用药物的复乳型载体及其应用
US20200129429A1 (en) * 2017-03-15 2020-04-30 Vivavax Inc. Biocompatible and biodegradable emulsions and compositions, and methods of use thereof
JP2019001770A (ja) * 2017-06-15 2019-01-10 エス・ピー・ジーテクノ株式会社 乳化型ワクチン製剤とその生成用デバイス
CN107596364B (zh) * 2017-09-19 2021-03-12 洛阳赛威生物科技有限公司 一种w/o/w佐剂组合物、制备的疫苗组合物及其制备方法
CN107595774B (zh) * 2017-10-24 2020-01-31 湖北医药学院 一种自乳化纳米复乳及其制备方法和应用
CN108578688B (zh) * 2018-04-03 2022-02-11 武汉轻工大学 多重纳米乳疫苗佐剂的制备方法
CN110585439B (zh) * 2019-09-30 2023-06-09 长春生物制品研究所有限责任公司 一种改良型的冻干甲型肝炎减毒活疫苗稳定剂、疫苗半成品、疫苗成品及其制备方法
CN113546162B (zh) * 2021-05-31 2023-07-18 江苏省农业科学院 一种支原体疫苗及其制备方法
CN113940994B (zh) * 2021-11-09 2023-09-15 南华大学 壳聚糖-Pickering乳液白细胞介素12佐剂体系的制备方法及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11106351A (ja) * 1997-10-02 1999-04-20 Chemo Sero Therapeut Res Inst オイルアジュバントワクチンおよびその製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2649012B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Emulsions multiphasiques injectables
FR2649013B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
US5622649A (en) * 1991-06-27 1997-04-22 Emory University Multiple emulsions and methods of preparation
ATE353225T1 (de) * 1995-11-30 2007-02-15 Chemo Sero Therapeut Res Inst Öladjuvierter impfstoff und verfahren zu seiner herstellung
US20060003012A9 (en) * 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11106351A (ja) * 1997-10-02 1999-04-20 Chemo Sero Therapeut Res Inst オイルアジュバントワクチンおよびその製造方法

Also Published As

Publication number Publication date
DE60002650D1 (de) 2003-06-18
AU780054B2 (en) 2005-02-24
JP2001131087A (ja) 2001-05-15
DK1097721T3 (da) 2003-09-01
CN1307903A (zh) 2001-08-15
EP1097721A3 (en) 2001-05-23
DE60002650T2 (de) 2004-03-11
TW581682B (en) 2004-04-01
EP1097721B1 (en) 2003-05-14
KR20010051463A (ko) 2001-06-25
ES2199734T3 (es) 2004-03-01
AU6971300A (en) 2001-05-10
EP1097721A2 (en) 2001-05-09
CN100384473C (zh) 2008-04-30
US20050158330A1 (en) 2005-07-21

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