KR100715641B1 - ｚｗｆ 유전자의 증폭에 의한 Ｌ-아미노산의 발효 제조방법 - Google Patents

ｚｗｆ 유전자의 증폭에 의한 Ｌ-아미노산의 발효 제조방법 Download PDF

Info

Publication number
KR100715641B1
KR100715641B1 KR1020017014792A KR20017014792A KR100715641B1 KR 100715641 B1 KR100715641 B1 KR 100715641B1 KR 1020017014792 A KR1020017014792 A KR 1020017014792A KR 20017014792 A KR20017014792 A KR 20017014792A KR 100715641 B1 KR100715641 B1 KR 100715641B1
Authority
KR
South Korea
Prior art keywords
ala
leu
gly
val
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020017014792A
Other languages
English (en)
Korean (ko)
Other versions
KR20020012578A (ko
Inventor
버크케빈
잠헤르만
에크겔링로타르
모리츠베른트
두니칸엘.카.
므코르맥애쉴링
스테이플톤클리오나
뫼켈벳티나
티어바하게오르크
Original Assignee
데구사 게엠베하
포르슝스젠트룸 율리히 게엠베하
내셔널 유니버시티 오브 아일랜드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 데구사 게엠베하, 포르슝스젠트룸 율리히 게엠베하, 내셔널 유니버시티 오브 아일랜드 filed Critical 데구사 게엠베하
Publication of KR20020012578A publication Critical patent/KR20020012578A/ko
Application granted granted Critical
Publication of KR100715641B1 publication Critical patent/KR100715641B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020017014792A 2000-03-20 2000-07-05 ｚｗｆ 유전자의 증폭에 의한 Ｌ-아미노산의 발효 제조방법 Expired - Fee Related KR100715641B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53126900A 2000-03-20 2000-03-20
US09/531,269 2000-03-20
PCT/EP2000/006303 WO2001070995A1 (en) 2000-03-20 2000-07-05 Process for the fermentative preparation of l-amino acids with amplification of the zwf gene

Publications (2)

Publication Number Publication Date
KR20020012578A KR20020012578A (ko) 2002-02-16
KR100715641B1 true KR100715641B1 (ko) 2007-05-08

Family

ID=24116957

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017014792A Expired - Fee Related KR100715641B1 (ko) 2000-03-20 2000-07-05 ｚｗｆ 유전자의 증폭에 의한 Ｌ-아미노산의 발효 제조방법

Country Status (13)

Country Link
EP (1) EP1179073B1 (enExample)
KR (1) KR100715641B1 (enExample)
CN (2) CN101029310B (enExample)
AT (1) ATE351908T1 (enExample)
AU (1) AU6821900A (enExample)
BR (1) BR0011283A (enExample)
CA (1) CA2374261C (enExample)
DE (2) DE60033026T4 (enExample)
HK (1) HK1047136A1 (enExample)
MX (1) MXPA01011644A (enExample)
PL (1) PL205611B1 (enExample)
SK (1) SK287997B6 (enExample)
WO (1) WO2001070995A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586214B1 (en) * 1999-09-15 2003-07-01 Degussa Ag Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene)
US6951729B1 (en) 1999-10-27 2005-10-04 Affinium Pharmaceuticals, Inc. High throughput screening method for biological agents affecting fatty acid biosynthesis
US7056697B2 (en) 2000-10-06 2006-06-06 Affinium Pharmaceuticals, Inc. FabK variant
US7033795B2 (en) 2000-10-06 2006-04-25 Affinium Pharmaceuticals, Inc. FabK variant
US7048926B2 (en) 2000-10-06 2006-05-23 Affinium Pharmaceuticals, Inc. Methods of agonizing and antagonizing FabK
US6821746B2 (en) 2000-10-06 2004-11-23 Affinium Pharmaceuticals, Inc. Methods of screening for FabK antagonists and agonists
DE10155505A1 (de) * 2001-11-13 2003-05-22 Basf Ag Gene die für Glucose-6-Phosphat-Dehydrogenase Proteine codieren
GB0208499D0 (en) * 2002-04-12 2002-05-22 Microscience Ltd Streptococcal genes
US7326546B2 (en) 2005-03-10 2008-02-05 Ajinomoto Co., Inc. Purine-derived substance-producing bacterium and a method for producing purine-derived substance
DE102005013676A1 (de) 2005-03-24 2006-09-28 Degussa Ag Allele des zwf-Gens aus coryneformen Bakterien
US20070092951A1 (en) 2005-03-24 2007-04-26 Degussa Ag Alleles of the zwf gene from coryneform bacteria
CN104845923B (zh) 2014-02-14 2018-03-23 中国科学院微生物研究所 生产l‑组氨酸的方法及其专用重组菌
CN106867952B (zh) * 2017-01-09 2019-10-18 天津科技大学 一株大肠杆菌基因工程菌及利用其生产l-苏氨酸的方法
CN107267568A (zh) * 2017-07-21 2017-10-20 徐州工程学院 利用spoT基因缺失菌株通过发酵生产L‑氨基酸的方法
CN109423504B (zh) * 2017-08-24 2022-10-04 廊坊梅花生物技术开发有限公司 生产l-色氨酸的菌株及用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09224661A (ja) 1996-02-23 1997-09-02 Mitsubishi Chem Corp グルコース−６−リン酸デヒドロゲナーゼおよびそれをコードするｄｎａ
CA2383865A1 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding metabolic pathway proteins
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
J. Bacteriol., Vol. 174(19) : 6238-6246 (1992. 10. *
J. Bacteriol., Vol. 174(19) : 6238-6246 (1992. 10. 공개) *
J. Bacteriol., Vol. 174(19) : 6238-6246 (1992. 10.*
J. Bacteriol., Vol. 177(21) : 6184-6194 (1995. 11. 공개) *
J. Bacteriol., Vol. 177(21) : 6184-6194 (1995. 11.*

Also Published As

Publication number Publication date
SK287997B6 (sk) 2012-09-03
MX244419B (enExample) 2007-03-26
WO2001070995A1 (en) 2001-09-27
EP1179073B1 (en) 2007-01-17
CN1353758A (zh) 2002-06-12
HK1047136A1 (zh) 2003-02-07
CN101029310A (zh) 2007-09-05
CA2374261C (en) 2010-04-20
CN1289676C (zh) 2006-12-13
CA2374261A1 (en) 2001-09-27
DE60033026T2 (de) 2007-11-15
DE60033026T4 (de) 2015-09-10
AU6821900A (en) 2001-10-03
PL358914A1 (en) 2004-08-23
BR0011283A (pt) 2002-03-05
KR20020012578A (ko) 2002-02-16
MXPA01011644A (es) 2003-02-27
PL205611B1 (pl) 2010-05-31
ATE351908T1 (de) 2007-02-15
DE60033026D1 (de) 2007-03-08
EP1179073A1 (en) 2002-02-13
CN101029310B (zh) 2010-12-08
SK16532001A3 (sk) 2002-07-02

Similar Documents

Publication Publication Date Title
US8445241B2 (en) Process for the preparation of L-amino acids
US20030199045A1 (en) Process for the preparation of L-amino acids with amplification of the zwf gene
KR100715641B1 (ko) ｚｗｆ 유전자의 증폭에 의한 Ｌ-아미노산의 발효 제조방법
US20030175911A1 (en) Process for the preparation of L-amino acids with amplification of the zwf gene
KR20010050840A (ko) ｅｎｏ 유전자를 암호화하는 신규한 뉴클레오타이드 서열
KR100826815B1 (ko) ｇｎｄ 유전자의 증폭을 이용한 Ｌ-아미노산의 발효적생산 방법
KR20010050423A (ko) ｄａｐＦ 유전자를 암호화하는 뉴클레오타이드 서열
US20050112733A1 (en) Process for the preparation of L-amino acids with amplification of the zwf gene
KR20010090510A (ko) ｄａｐＣ 유전자를 암호화하는 뉴클레오타이드 서열 및Ｌ-라이신의 생산 방법
EP1179084B1 (en) Process for the fermentative preparation of l-amino acids with amplification of the tkt gene
US20030166173A1 (en) Nucleotide sequences coding for the glbO gene
US20030109014A1 (en) Process for the fermentative preparation of L-amino acids with amplification of the tkt gene
WO2005075631A1 (en) Process for the preparation of l-amino acids with amplification of the zwf gene
KR20010062078A (ko) ｇｌｋ 유전자를 암호화하는 뉴클레오티드 서열
KR20060129352A (ko) ｚｗｆ 유전자의 증폭을 이용한 Ｌ-아미노산의 제조 방법
MXPA06007762A (en) Process for the preparation of l-amino acids with amplification of the zwf gene

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PN2301 Change of applicant

St.27 status event code: A-3-3-R10-R13-asn-PN2301

St.27 status event code: A-3-3-R10-R11-asn-PN2301

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

FPAY Annual fee payment

Payment date: 20130419

Year of fee payment: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

FPAY Annual fee payment

Payment date: 20140417

Year of fee payment: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

FPAY Annual fee payment

Payment date: 20150423

Year of fee payment: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

FPAY Annual fee payment

Payment date: 20160421

Year of fee payment: 10

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

FPAY Annual fee payment

Payment date: 20170420

Year of fee payment: 11

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 11

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20180502

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20180502

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301