KR100712570B1 - 알콜 의존성 치료약의 제조에서 플루마제닐의 용도 - Google Patents

알콜 의존성 치료약의 제조에서 플루마제닐의 용도 Download PDF

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Publication number
KR100712570B1
KR100712570B1 KR1020037009461A KR20037009461A KR100712570B1 KR 100712570 B1 KR100712570 B1 KR 100712570B1 KR 1020037009461 A KR1020037009461 A KR 1020037009461A KR 20037009461 A KR20037009461 A KR 20037009461A KR 100712570 B1 KR100712570 B1 KR 100712570B1
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South Korea
Prior art keywords
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flumazenyl
treatment
drug
benzodiazepine
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Expired - Fee Related
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KR1020037009461A
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English (en)
Korean (ko)
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KR20040020046A (ko
Inventor
후안 호세 레가르다 아바네즈
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하이디엄, 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020037009461A 2001-01-17 2002-01-10 알콜 의존성 치료약의 제조에서 플루마제닐의 용도 Expired - Fee Related KR100712570B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200100106 2001-01-17
ESP200100106 2001-01-17
PCT/ES2002/000008 WO2002056964A1 (es) 2001-01-17 2002-01-10 Empleo de flumazenilo en la elaboración de una medicación para el tratamiento de la dependencia de alcohol

Publications (2)

Publication Number Publication Date
KR20040020046A KR20040020046A (ko) 2004-03-06
KR100712570B1 true KR100712570B1 (ko) 2007-05-02

Family

ID=8496426

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037009461A Expired - Fee Related KR100712570B1 (ko) 2001-01-17 2002-01-10 알콜 의존성 치료약의 제조에서 플루마제닐의 용도

Country Status (22)

Country Link
US (2) US7348321B2 (https=)
EP (1) EP1374952B1 (https=)
JP (2) JP2004519461A (https=)
KR (1) KR100712570B1 (https=)
CN (1) CN1486205A (https=)
AT (1) ATE338575T1 (https=)
AU (1) AU2002226427B2 (https=)
BR (1) BR0206549A (https=)
CA (1) CA2433833C (https=)
CR (1) CR7049A (https=)
CY (1) CY1107500T1 (https=)
DE (1) DE60214527T2 (https=)
DK (1) DK1374952T3 (https=)
ES (1) ES2269661T3 (https=)
IL (1) IL156798A0 (https=)
MX (1) MXPA03006411A (https=)
NZ (2) NZ539400A (https=)
PT (1) PT1374952E (https=)
RU (1) RU2300378C2 (https=)
UA (1) UA78199C2 (https=)
WO (1) WO2002056964A1 (https=)
ZA (1) ZA200305922B (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050192271A1 (en) * 2003-07-15 2005-09-01 Hythiam, Inc. Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
US20060172996A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
US20060172998A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
JP2008538748A (ja) 2005-04-07 2008-11-06 ハイシアム， インコーポレイテッド 不安、物質乱用及び依存の予防のための改良型方法及び組成物
US20060263304A1 (en) * 2005-05-23 2006-11-23 Halikas James A Method of controlling alcohol intake and reversing alcohol effects
EP3251670A1 (en) 2007-08-06 2017-12-06 Biotie Therapies, Inc. Methods for treating dependence
US20110034442A1 (en) * 2007-08-08 2011-02-10 Jaun Jose Legarda Ibanez Use and Methods of Use for an Antagonist of the Serotin3 Receptor (5-HT3) and a Selective Modulator of Chloride Channels for the Treatment of Addiction to or Dependence on Medicines/Drugs or Nervous System Disorders
US9283212B2 (en) 2009-02-20 2016-03-15 Palmaya Pty Ltd Pharmaceutical preparation and delivery system
US8387589B2 (en) * 2009-04-29 2013-03-05 Marine Canada Acqusition Inc. Position sensor for an output shaft used in a shift and throttle system
US20100280684A1 (en) * 2009-04-29 2010-11-04 Pierre Garon Synchronization of shift and throttle controls in a marine vessel
US8930050B2 (en) * 2009-04-29 2015-01-06 Marine Canada Acquisition Inc. Method and system for increasing or decreasing engine throttle in a marine vessel
US8347859B2 (en) * 2009-04-29 2013-01-08 Marine Canada Acquisition Inc. Automatic throttle calibration in a marine vessel
US8406944B2 (en) * 2010-02-10 2013-03-26 Pierre Garon Control system and method for starting and stopping marine engines
US8845490B2 (en) 2010-02-10 2014-09-30 Marine Canada Acquisition Inc. Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
US8182396B2 (en) * 2010-02-10 2012-05-22 Marine Canada Acquisition In.c Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
ES2702848T3 (es) 2011-02-23 2019-03-05 Coeruleus Ltd Complejos de flumazenil, composiciones que los comprenden y usos de los mismos
RU2468799C1 (ru) * 2011-08-03 2012-12-10 Общество с ограниченной ответственностью "Урал Крафт" Способ купирования алкогольного абстинентного синдрома посредством блокады бензодиазепиновых рецепторов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US5519017A (en) * 1990-03-29 1996-05-21 Lts Lohmann Therapie-Systeme Gmbh + Co. Kg Pharmaceutic formulation for the treatment of alcoholism
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use
GB9420010D0 (en) * 1994-10-01 1994-11-16 Marck Sharp & Dohme Limited Nucleic acids
US20030176456A1 (en) * 2001-12-21 2003-09-18 June Harry L. Methods for reducing alcohol cravings in chronic alcoholics
US6740677B2 (en) * 2002-08-19 2004-05-25 Hong Xue Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
1020037009461 - 686365

Also Published As

Publication number Publication date
US20040092509A1 (en) 2004-05-13
KR20040020046A (ko) 2004-03-06
PT1374952E (pt) 2006-12-29
ES2269661T3 (es) 2007-04-01
NZ539400A (en) 2006-04-28
RU2003125274A (ru) 2005-01-20
EP1374952B1 (en) 2006-09-06
UA78199C2 (en) 2007-03-15
AU2002226427B2 (en) 2006-11-16
ZA200305922B (en) 2004-08-02
JP2008201796A (ja) 2008-09-04
MXPA03006411A (es) 2004-12-02
CR7049A (es) 2008-02-20
DE60214527T2 (de) 2007-04-05
DE60214527D1 (de) 2006-10-19
CN1486205A (zh) 2004-03-31
HK1061661A1 (en) 2004-09-30
US20080132492A1 (en) 2008-06-05
DK1374952T3 (da) 2007-01-02
EP1374952A1 (en) 2004-01-02
RU2300378C2 (ru) 2007-06-10
JP2004519461A (ja) 2004-07-02
NZ527583A (en) 2006-03-31
IL156798A0 (en) 2004-02-08
CA2433833A1 (en) 2002-07-25
CY1107500T1 (el) 2013-03-13
BR0206549A (pt) 2004-02-25
CA2433833C (en) 2009-06-02
WO2002056964A1 (es) 2002-07-25
US7348321B2 (en) 2008-03-25
ATE338575T1 (de) 2006-09-15

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