JP2004519461A - アルコール依存症治療用薬剤の製造時におけるフルマゼニルの使用 - Google Patents

アルコール依存症治療用薬剤の製造時におけるフルマゼニルの使用 Download PDF

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Publication number
JP2004519461A
JP2004519461A JP2002557469A JP2002557469A JP2004519461A JP 2004519461 A JP2004519461 A JP 2004519461A JP 2002557469 A JP2002557469 A JP 2002557469A JP 2002557469 A JP2002557469 A JP 2002557469A JP 2004519461 A JP2004519461 A JP 2004519461A
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JP
Japan
Prior art keywords
flumazenil
treatment
therapeutically effective
alcoholism
effective amount
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002557469A
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English (en)
Japanese (ja)
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JP2004519461A5 (https=
Inventor
イバニェス，フアン ホセ レガルダ
Original Assignee
ハイチアム，インコーポレイテッド
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Application filed by ハイチアム，インコーポレイテッド filed Critical ハイチアム，インコーポレイテッド
Publication of JP2004519461A publication Critical patent/JP2004519461A/ja
Publication of JP2004519461A5 publication Critical patent/JP2004519461A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2002557469A 2001-01-17 2002-01-10 アルコール依存症治療用薬剤の製造時におけるフルマゼニルの使用 Pending JP2004519461A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200100106 2001-01-17
PCT/ES2002/000008 WO2002056964A1 (es) 2001-01-17 2002-01-10 Empleo de flumazenilo en la elaboración de una medicación para el tratamiento de la dependencia de alcohol

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008116697A Division JP2008201796A (ja) 2001-01-17 2008-04-28 アルコール依存症治療用の薬剤

Publications (2)

Publication Number Publication Date
JP2004519461A true JP2004519461A (ja) 2004-07-02
JP2004519461A5 JP2004519461A5 (https=) 2008-07-03

Family

ID=8496426

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002557469A Pending JP2004519461A (ja) 2001-01-17 2002-01-10 アルコール依存症治療用薬剤の製造時におけるフルマゼニルの使用
JP2008116697A Pending JP2008201796A (ja) 2001-01-17 2008-04-28 アルコール依存症治療用の薬剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008116697A Pending JP2008201796A (ja) 2001-01-17 2008-04-28 アルコール依存症治療用の薬剤

Country Status (22)

Country Link
US (2) US7348321B2 (https=)
EP (1) EP1374952B1 (https=)
JP (2) JP2004519461A (https=)
KR (1) KR100712570B1 (https=)
CN (1) CN1486205A (https=)
AT (1) ATE338575T1 (https=)
AU (1) AU2002226427B2 (https=)
BR (1) BR0206549A (https=)
CA (1) CA2433833C (https=)
CR (1) CR7049A (https=)
CY (1) CY1107500T1 (https=)
DE (1) DE60214527T2 (https=)
DK (1) DK1374952T3 (https=)
ES (1) ES2269661T3 (https=)
IL (1) IL156798A0 (https=)
MX (1) MXPA03006411A (https=)
NZ (2) NZ539400A (https=)
PT (1) PT1374952E (https=)
RU (1) RU2300378C2 (https=)
UA (1) UA78199C2 (https=)
WO (1) WO2002056964A1 (https=)
ZA (1) ZA200305922B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008536921A (ja) * 2005-04-21 2008-09-11 ハイシアム， インコーポレイテッド アルコール及び／又は刺激物質の乱用を治療するための選択的塩素イオンチャネルモジュレーターの使用

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060172996A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
US20060172998A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
JP2008538748A (ja) 2005-04-07 2008-11-06 ハイシアム， インコーポレイテッド 不安、物質乱用及び依存の予防のための改良型方法及び組成物
US20060263304A1 (en) * 2005-05-23 2006-11-23 Halikas James A Method of controlling alcohol intake and reversing alcohol effects
EP3251670A1 (en) 2007-08-06 2017-12-06 Biotie Therapies, Inc. Methods for treating dependence
US20110034442A1 (en) * 2007-08-08 2011-02-10 Jaun Jose Legarda Ibanez Use and Methods of Use for an Antagonist of the Serotin3 Receptor (5-HT3) and a Selective Modulator of Chloride Channels for the Treatment of Addiction to or Dependence on Medicines/Drugs or Nervous System Disorders
US9283212B2 (en) 2009-02-20 2016-03-15 Palmaya Pty Ltd Pharmaceutical preparation and delivery system
US8387589B2 (en) * 2009-04-29 2013-03-05 Marine Canada Acqusition Inc. Position sensor for an output shaft used in a shift and throttle system
US20100280684A1 (en) * 2009-04-29 2010-11-04 Pierre Garon Synchronization of shift and throttle controls in a marine vessel
US8930050B2 (en) * 2009-04-29 2015-01-06 Marine Canada Acquisition Inc. Method and system for increasing or decreasing engine throttle in a marine vessel
US8347859B2 (en) * 2009-04-29 2013-01-08 Marine Canada Acquisition Inc. Automatic throttle calibration in a marine vessel
US8406944B2 (en) * 2010-02-10 2013-03-26 Pierre Garon Control system and method for starting and stopping marine engines
US8845490B2 (en) 2010-02-10 2014-09-30 Marine Canada Acquisition Inc. Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
US8182396B2 (en) * 2010-02-10 2012-05-22 Marine Canada Acquisition In.c Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
ES2702848T3 (es) 2011-02-23 2019-03-05 Coeruleus Ltd Complejos de flumazenil, composiciones que los comprenden y usos de los mismos
RU2468799C1 (ru) * 2011-08-03 2012-12-10 Общество с ограниченной ответственностью "Урал Крафт" Способ купирования алкогольного абстинентного синдрома посредством блокады бензодиазепиновых рецепторов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US5519017A (en) * 1990-03-29 1996-05-21 Lts Lohmann Therapie-Systeme Gmbh + Co. Kg Pharmaceutic formulation for the treatment of alcoholism
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use
GB9420010D0 (en) * 1994-10-01 1994-11-16 Marck Sharp & Dohme Limited Nucleic acids
US20030176456A1 (en) * 2001-12-21 2003-09-18 June Harry L. Methods for reducing alcohol cravings in chronic alcoholics
US6740677B2 (en) * 2002-08-19 2004-05-25 Hong Xue Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008536921A (ja) * 2005-04-21 2008-09-11 ハイシアム， インコーポレイテッド アルコール及び／又は刺激物質の乱用を治療するための選択的塩素イオンチャネルモジュレーターの使用

Also Published As

Publication number Publication date
US20040092509A1 (en) 2004-05-13
KR20040020046A (ko) 2004-03-06
PT1374952E (pt) 2006-12-29
ES2269661T3 (es) 2007-04-01
KR100712570B1 (ko) 2007-05-02
NZ539400A (en) 2006-04-28
RU2003125274A (ru) 2005-01-20
EP1374952B1 (en) 2006-09-06
UA78199C2 (en) 2007-03-15
AU2002226427B2 (en) 2006-11-16
ZA200305922B (en) 2004-08-02
JP2008201796A (ja) 2008-09-04
MXPA03006411A (es) 2004-12-02
CR7049A (es) 2008-02-20
DE60214527T2 (de) 2007-04-05
DE60214527D1 (de) 2006-10-19
CN1486205A (zh) 2004-03-31
HK1061661A1 (en) 2004-09-30
US20080132492A1 (en) 2008-06-05
DK1374952T3 (da) 2007-01-02
EP1374952A1 (en) 2004-01-02
RU2300378C2 (ru) 2007-06-10
NZ527583A (en) 2006-03-31
IL156798A0 (en) 2004-02-08
CA2433833A1 (en) 2002-07-25
CY1107500T1 (el) 2013-03-13
BR0206549A (pt) 2004-02-25
CA2433833C (en) 2009-06-02
WO2002056964A1 (es) 2002-07-25
US7348321B2 (en) 2008-03-25
ATE338575T1 (de) 2006-09-15

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