CY1107500T1 - Η χρηση του φλουμαζενιλ στην αναπτυξη ενος φαρμακου για τη θepαπευτικη αντιμετωπιση της εξαρτησης απο το αλκοολ - Google Patents
Η χρηση του φλουμαζενιλ στην αναπτυξη ενος φαρμακου για τη θepαπευτικη αντιμετωπιση της εξαρτησης απο το αλκοολInfo
- Publication number
- CY1107500T1 CY1107500T1 CY20061101651T CY061101651T CY1107500T1 CY 1107500 T1 CY1107500 T1 CY 1107500T1 CY 20061101651 T CY20061101651 T CY 20061101651T CY 061101651 T CY061101651 T CY 061101651T CY 1107500 T1 CY1107500 T1 CY 1107500T1
- Authority
- CY
- Cyprus
- Prior art keywords
- flumazenil
- drug
- development
- alternative treatment
- alcohol addiction
- Prior art date
Links
- OFBIFZUFASYYRE-UHFFFAOYSA-N flumazenil Chemical compound C1N(C)C(=O)C2=CC(F)=CC=C2N2C=NC(C(=O)OCC)=C21 OFBIFZUFASYYRE-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004381 flumazenil Drugs 0.000 title abstract 3
- 208000007848 Alcoholism Diseases 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 201000007930 alcohol dependence Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Addiction (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200100106 | 2001-01-17 | ||
| EP02716090A EP1374952B1 (en) | 2001-01-17 | 2002-01-10 | Use of flumazenil in developing a drug for the treatment of alcohol dependence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1107500T1 true CY1107500T1 (el) | 2013-03-13 |
Family
ID=8496426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101651T CY1107500T1 (el) | 2001-01-17 | 2006-11-14 | Η χρηση του φλουμαζενιλ στην αναπτυξη ενος φαρμακου για τη θepαπευτικη αντιμετωπιση της εξαρτησης απο το αλκοολ |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7348321B2 (https=) |
| EP (1) | EP1374952B1 (https=) |
| JP (2) | JP2004519461A (https=) |
| KR (1) | KR100712570B1 (https=) |
| CN (1) | CN1486205A (https=) |
| AT (1) | ATE338575T1 (https=) |
| AU (1) | AU2002226427B2 (https=) |
| BR (1) | BR0206549A (https=) |
| CA (1) | CA2433833C (https=) |
| CR (1) | CR7049A (https=) |
| CY (1) | CY1107500T1 (https=) |
| DE (1) | DE60214527T2 (https=) |
| DK (1) | DK1374952T3 (https=) |
| ES (1) | ES2269661T3 (https=) |
| IL (1) | IL156798A0 (https=) |
| MX (1) | MXPA03006411A (https=) |
| NZ (2) | NZ539400A (https=) |
| PT (1) | PT1374952E (https=) |
| RU (1) | RU2300378C2 (https=) |
| UA (1) | UA78199C2 (https=) |
| WO (1) | WO2002056964A1 (https=) |
| ZA (1) | ZA200305922B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050192271A1 (en) * | 2003-07-15 | 2005-09-01 | Hythiam, Inc. | Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse |
| US20060172996A1 (en) * | 2005-02-03 | 2006-08-03 | Halikas James A | Method of preventing relapse in the abstinent substance dependent individual |
| US20060172998A1 (en) * | 2005-02-03 | 2006-08-03 | Halikas James A | Method of preventing relapse in the abstinent substance dependent individual |
| JP2008538748A (ja) | 2005-04-07 | 2008-11-06 | ハイシアム， インコーポレイテッド | 不安、物質乱用及び依存の予防のための改良型方法及び組成物 |
| US20060263304A1 (en) * | 2005-05-23 | 2006-11-23 | Halikas James A | Method of controlling alcohol intake and reversing alcohol effects |
| EP3251670A1 (en) | 2007-08-06 | 2017-12-06 | Biotie Therapies, Inc. | Methods for treating dependence |
| US20110034442A1 (en) * | 2007-08-08 | 2011-02-10 | Jaun Jose Legarda Ibanez | Use and Methods of Use for an Antagonist of the Serotin3 Receptor (5-HT3) and a Selective Modulator of Chloride Channels for the Treatment of Addiction to or Dependence on Medicines/Drugs or Nervous System Disorders |
| US9283212B2 (en) | 2009-02-20 | 2016-03-15 | Palmaya Pty Ltd | Pharmaceutical preparation and delivery system |
| US8387589B2 (en) * | 2009-04-29 | 2013-03-05 | Marine Canada Acqusition Inc. | Position sensor for an output shaft used in a shift and throttle system |
| US20100280684A1 (en) * | 2009-04-29 | 2010-11-04 | Pierre Garon | Synchronization of shift and throttle controls in a marine vessel |
| US8930050B2 (en) * | 2009-04-29 | 2015-01-06 | Marine Canada Acquisition Inc. | Method and system for increasing or decreasing engine throttle in a marine vessel |
| US8347859B2 (en) * | 2009-04-29 | 2013-01-08 | Marine Canada Acquisition Inc. | Automatic throttle calibration in a marine vessel |
| US8406944B2 (en) * | 2010-02-10 | 2013-03-26 | Pierre Garon | Control system and method for starting and stopping marine engines |
| US8845490B2 (en) | 2010-02-10 | 2014-09-30 | Marine Canada Acquisition Inc. | Method and system for delaying shift and throttle commands based on engine speed in a marine vessel |
| US8182396B2 (en) * | 2010-02-10 | 2012-05-22 | Marine Canada Acquisition In.c | Method and system for delaying shift and throttle commands based on engine speed in a marine vessel |
| ES2702848T3 (es) | 2011-02-23 | 2019-03-05 | Coeruleus Ltd | Complejos de flumazenil, composiciones que los comprenden y usos de los mismos |
| RU2468799C1 (ru) * | 2011-08-03 | 2012-12-10 | Общество с ограниченной ответственностью "Урал Крафт" | Способ купирования алкогольного абстинентного синдрома посредством блокады бензодиазепиновых рецепторов |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316893A (en) * | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
| US5519017A (en) * | 1990-03-29 | 1996-05-21 | Lts Lohmann Therapie-Systeme Gmbh + Co. Kg | Pharmaceutic formulation for the treatment of alcoholism |
| SE9100860D0 (sv) * | 1991-03-22 | 1991-03-22 | Kabi Pharmacia Ab | New use |
| GB9420010D0 (en) * | 1994-10-01 | 1994-11-16 | Marck Sharp & Dohme Limited | Nucleic acids |
| US20030176456A1 (en) * | 2001-12-21 | 2003-09-18 | June Harry L. | Methods for reducing alcohol cravings in chronic alcoholics |
| US6740677B2 (en) * | 2002-08-19 | 2004-05-25 | Hong Xue | Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids |
-
2002
- 2002-01-10 KR KR1020037009461A patent/KR100712570B1/ko not_active Expired - Fee Related
- 2002-01-10 PT PT02716090T patent/PT1374952E/pt unknown
- 2002-01-10 DE DE60214527T patent/DE60214527T2/de not_active Expired - Lifetime
- 2002-01-10 ZA ZA200305922A patent/ZA200305922B/en unknown
- 2002-01-10 RU RU2003125274/15A patent/RU2300378C2/ru not_active IP Right Cessation
- 2002-01-10 BR BR0206549-5A patent/BR0206549A/pt not_active Application Discontinuation
- 2002-01-10 EP EP02716090A patent/EP1374952B1/en not_active Expired - Lifetime
- 2002-01-10 DK DK02716090T patent/DK1374952T3/da active
- 2002-01-10 JP JP2002557469A patent/JP2004519461A/ja active Pending
- 2002-01-10 CN CNA028038029A patent/CN1486205A/zh active Pending
- 2002-01-10 AT AT02716090T patent/ATE338575T1/de active
- 2002-01-10 NZ NZ539400A patent/NZ539400A/en not_active IP Right Cessation
- 2002-01-10 MX MXPA03006411A patent/MXPA03006411A/es active IP Right Grant
- 2002-01-10 AU AU2002226427A patent/AU2002226427B2/en not_active Ceased
- 2002-01-10 CA CA002433833A patent/CA2433833C/en not_active Expired - Fee Related
- 2002-01-10 WO PCT/ES2002/000008 patent/WO2002056964A1/es not_active Ceased
- 2002-01-10 NZ NZ527583A patent/NZ527583A/xx not_active IP Right Cessation
- 2002-01-10 IL IL15679802A patent/IL156798A0/xx unknown
- 2002-01-10 ES ES02716090T patent/ES2269661T3/es not_active Expired - Lifetime
- 2002-10-01 UA UA2003087768A patent/UA78199C2/uk unknown
-
2003
- 2003-07-15 US US10/621,229 patent/US7348321B2/en not_active Expired - Lifetime
- 2003-08-06 CR CR7049A patent/CR7049A/es unknown
-
2006
- 2006-11-14 CY CY20061101651T patent/CY1107500T1/el unknown
-
2008
- 2008-02-06 US US12/026,643 patent/US20080132492A1/en not_active Abandoned
- 2008-04-28 JP JP2008116697A patent/JP2008201796A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20040092509A1 (en) | 2004-05-13 |
| KR20040020046A (ko) | 2004-03-06 |
| PT1374952E (pt) | 2006-12-29 |
| ES2269661T3 (es) | 2007-04-01 |
| KR100712570B1 (ko) | 2007-05-02 |
| NZ539400A (en) | 2006-04-28 |
| RU2003125274A (ru) | 2005-01-20 |
| EP1374952B1 (en) | 2006-09-06 |
| UA78199C2 (en) | 2007-03-15 |
| AU2002226427B2 (en) | 2006-11-16 |
| ZA200305922B (en) | 2004-08-02 |
| JP2008201796A (ja) | 2008-09-04 |
| MXPA03006411A (es) | 2004-12-02 |
| CR7049A (es) | 2008-02-20 |
| DE60214527T2 (de) | 2007-04-05 |
| DE60214527D1 (de) | 2006-10-19 |
| CN1486205A (zh) | 2004-03-31 |
| HK1061661A1 (en) | 2004-09-30 |
| US20080132492A1 (en) | 2008-06-05 |
| DK1374952T3 (da) | 2007-01-02 |
| EP1374952A1 (en) | 2004-01-02 |
| RU2300378C2 (ru) | 2007-06-10 |
| JP2004519461A (ja) | 2004-07-02 |
| NZ527583A (en) | 2006-03-31 |
| IL156798A0 (en) | 2004-02-08 |
| CA2433833A1 (en) | 2002-07-25 |
| BR0206549A (pt) | 2004-02-25 |
| CA2433833C (en) | 2009-06-02 |
| WO2002056964A1 (es) | 2002-07-25 |
| US7348321B2 (en) | 2008-03-25 |
| ATE338575T1 (de) | 2006-09-15 |
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