CY1106845T1 - Χρηση της φλουμαζενιλης για την παρασκευη ενος φαρμακου για την αγωγη της εξαρτησεως απο την κοκαϊνη - Google Patents

Χρηση της φλουμαζενιλης για την παρασκευη ενος φαρμακου για την αγωγη της εξαρτησεως απο την κοκαϊνη

Info

Publication number
CY1106845T1
CY1106845T1 CY20071101148T CY071101148T CY1106845T1 CY 1106845 T1 CY1106845 T1 CY 1106845T1 CY 20071101148 T CY20071101148 T CY 20071101148T CY 071101148 T CY071101148 T CY 071101148T CY 1106845 T1 CY1106845 T1 CY 1106845T1
Authority
CY
Cyprus
Prior art keywords
flumazenil
treatment
preparation
cocaine dependence
drug
Prior art date
Application number
CY20071101148T
Other languages
English (en)
Inventor
Juan Jose Legarda Ibanez
Original Assignee
Hythiam, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hythiam, Inc. filed Critical Hythiam, Inc.
Publication of CY1106845T1 publication Critical patent/CY1106845T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)

Abstract

Η εφεύρεση αναφέρεται στη χρήση της φλουμαζενίλης για την παρασκευή ενός φαρμάκου για την αγωγή της εξαρτήσεως από την κοκαΐνη. Η φλουμαζενίλη μπορεί να χορηγείται διαδοχικά σε μικρές ποσότητες ανά σύντομα διαστήματα μέχρις ότου χορηγηθεί μία θεραπευτικά αποτελεσματική ποσότητα για την αγωγή της εξαρτήσεως από την κοκαΐνη.
CY20071101148T 2001-02-15 2007-09-05 Χρηση της φλουμαζενιλης για την παρασκευη ενος φαρμακου για την αγωγη της εξαρτησεως απο την κοκαϊνη CY1106845T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200100342 2001-02-15
PCT/ES2002/000061 WO2002064213A1 (es) 2001-02-15 2002-02-08 Empleo de flumazenilo en la elaboracion de un medicamento para el tratamiento de la dependencia de cocaina

Publications (1)

Publication Number Publication Date
CY1106845T1 true CY1106845T1 (el) 2012-05-23

Family

ID=8496743

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101148T CY1106845T1 (el) 2001-02-15 2007-09-05 Χρηση της φλουμαζενιλης για την παρασκευη ενος φαρμακου για την αγωγη της εξαρτησεως απο την κοκαϊνη

Country Status (21)

Country Link
US (2) US7186711B2 (el)
EP (1) EP1378267B1 (el)
JP (2) JP4272885B2 (el)
KR (1) KR100712571B1 (el)
CN (1) CN1327843C (el)
AT (1) ATE363923T1 (el)
AU (1) AU2002231811B2 (el)
BR (1) BR0207866A (el)
CA (1) CA2436511C (el)
CY (1) CY1106845T1 (el)
DE (1) DE60220512T2 (el)
DK (1) DK1378267T3 (el)
ES (1) ES2287255T3 (el)
HK (1) HK1061817A1 (el)
IL (1) IL157144A0 (el)
MX (1) MXPA03007281A (el)
NZ (1) NZ528164A (el)
PT (1) PT1378267E (el)
RU (1) RU2322985C2 (el)
UA (1) UA79586C2 (el)
WO (1) WO2002064213A1 (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050192271A1 (en) * 2003-07-15 2005-09-01 Hythiam, Inc. Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
EP1378267B1 (en) 2001-02-15 2007-06-06 Hythiam, Inc. Use of flumazenil to produce a medicament for the treatment of cocaine dependency
WO2006110642A2 (en) * 2005-04-07 2006-10-19 Hythiam, Inc. Improved methods of and compositions for the prevention of anxiety, substance abuse, and dependence
US7855196B2 (en) 2005-08-22 2010-12-21 Pierre Mainville Composition comprising a benzodiazepine agonist and a benzodiazepine antagonist
ES2289935B1 (es) * 2006-07-14 2008-12-16 Juan Jose Legarda Ibañez Empleo de flumazenilo en la elaboracion de un medicamento para el tratamiento de la patologia depresiva.
WO2009027564A1 (es) * 2007-08-08 2009-03-05 Legarda Ibanez Juan Jose Uso y métodos de uso de un antagonista del receptor (5-ht3) de la serotonina3 y un modulador selectivo de los canales de cloruro para el tratamiento de la adicción a o la dependencia de fármacos/drogas o trastornos del sistema nervioso central
US9396280B2 (en) * 2008-06-23 2016-07-19 Microsoft Technology Licensing, Llc Command driven web site browsing
CN103502224A (zh) 2011-02-23 2014-01-08 克鲁莱斯有限公司 氟马西尼络合物、包含该络合物的组合物及其用途
WO2014113617A1 (en) 2013-01-21 2014-07-24 Innovative Finishes LLC Refurbished component, electronic device including the same, and method of refurbishing a component of an electronic device
WO2015054730A1 (en) * 2013-10-14 2015-04-23 Palmaya Pty Ltd Compositions and methods of administering same
CN107115359A (zh) * 2016-02-24 2017-09-01 郑恩哲 阻断海洛因或吗啡毒品中毒路径的点滴处方及其应用
US11878001B2 (en) 2017-07-31 2024-01-23 Novartis Ag Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028611A (en) * 1989-06-29 1991-07-02 The Regents Of The University Of Minnesota Treatment for cocaine use
US5229120A (en) * 1992-02-05 1993-07-20 Devincent James F Treatment for cocaine abuse
GB9420010D0 (en) 1994-10-01 1994-11-16 Marck Sharp & Dohme Limited Nucleic acids
WO2000030648A1 (en) * 1998-11-23 2000-06-02 Sepracor Inc. 2-hydroxymethylolanzapine compositions and methods
EP1125579A3 (en) * 2000-01-18 2003-01-02 Pfizer Products Inc. Uses of agrp-melanocortin receptor binding modulating compounds
EP1378267B1 (en) 2001-02-15 2007-06-06 Hythiam, Inc. Use of flumazenil to produce a medicament for the treatment of cocaine dependency
US6740677B2 (en) 2002-08-19 2004-05-25 Hong Xue Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids

Also Published As

Publication number Publication date
US7186711B2 (en) 2007-03-06
HK1061817A1 (en) 2004-10-08
KR20040010592A (ko) 2004-01-31
EP1378267B1 (en) 2007-06-06
UA79586C2 (en) 2007-07-10
US20070142364A1 (en) 2007-06-21
BR0207866A (pt) 2004-03-23
IL157144A0 (en) 2004-02-08
RU2322985C2 (ru) 2008-04-27
DE60220512T2 (de) 2008-02-07
EP1378267A1 (en) 2004-01-07
ES2287255T3 (es) 2007-12-16
JP2008201799A (ja) 2008-09-04
JP2004521904A (ja) 2004-07-22
WO2002064213A1 (es) 2002-08-22
MXPA03007281A (es) 2005-01-25
DE60220512D1 (de) 2007-07-19
KR100712571B1 (ko) 2007-05-02
CN1491125A (zh) 2004-04-21
CA2436511A1 (en) 2002-08-22
CA2436511C (en) 2009-08-04
RU2003127718A (ru) 2005-01-27
DK1378267T3 (da) 2007-10-08
NZ528164A (en) 2006-03-31
CN1327843C (zh) 2007-07-25
AU2002231811B2 (en) 2006-02-16
US20060122219A1 (en) 2006-06-08
ATE363923T1 (de) 2007-06-15
JP4272885B2 (ja) 2009-06-03
PT1378267E (pt) 2007-09-11

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