KR100701212B1 - 활성성분함유 피부부착 치료 시스템 - Google Patents

활성성분함유 피부부착 치료 시스템 Download PDF

Info

Publication number
KR100701212B1
KR100701212B1 KR1020017005127A KR20017005127A KR100701212B1 KR 100701212 B1 KR100701212 B1 KR 100701212B1 KR 1020017005127 A KR1020017005127 A KR 1020017005127A KR 20017005127 A KR20017005127 A KR 20017005127A KR 100701212 B1 KR100701212 B1 KR 100701212B1
Authority
KR
South Korea
Prior art keywords
polymer
active ingredient
treatment system
containing matrix
adhesion treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020017005127A
Other languages
English (en)
Korean (ko)
Other versions
KR20010080321A (ko
Inventor
벨톨드아침
Original Assignee
엘티에스 로만 테라피-시스템 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 엘티에스 로만 테라피-시스템 악티엔게젤샤프트 filed Critical 엘티에스 로만 테라피-시스템 악티엔게젤샤프트
Publication of KR20010080321A publication Critical patent/KR20010080321A/ko
Application granted granted Critical
Publication of KR100701212B1 publication Critical patent/KR100701212B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/18—Layered products comprising a layer of synthetic resin characterised by the use of special additives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/02—Physical, chemical or physicochemical properties
    • B32B7/027—Thermal properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • B32B7/06—Interconnection of layers permitting easy separation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2250/00—Layers arrangement
    • B32B2250/05—5 or more layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2535/00—Medical equipment, e.g. bandage, prostheses or catheter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2556/00—Patches, e.g. medical patches, repair patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020017005127A 1999-08-25 2000-08-14 활성성분함유 피부부착 치료 시스템 Expired - Lifetime KR100701212B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19940238.8 1999-08-25
DE19940238A DE19940238A1 (de) 1999-08-25 1999-08-25 Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten

Publications (2)

Publication Number Publication Date
KR20010080321A KR20010080321A (ko) 2001-08-22
KR100701212B1 true KR100701212B1 (ko) 2007-03-29

Family

ID=7919502

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017005127A Expired - Lifetime KR100701212B1 (ko) 1999-08-25 2000-08-14 활성성분함유 피부부착 치료 시스템

Country Status (10)

Country Link
US (2) US7279178B1 (https=)
EP (1) EP1143939B1 (https=)
JP (1) JP2003507417A (https=)
KR (1) KR100701212B1 (https=)
AR (1) AR025390A1 (https=)
AT (1) ATE404182T1 (https=)
AU (1) AU6995700A (https=)
DE (2) DE19940238A1 (https=)
ES (1) ES2312361T3 (https=)
WO (1) WO2001013899A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
PT1256339E (pt) * 2001-05-08 2004-02-27 Lohmann Therapie Syst Lts Sistema terapeutico transdermico para doenca de parkinson que induz niveis plasmaticos altos de rotigotina
US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
EP1256340B1 (en) * 2001-05-08 2003-08-13 Schwarz Pharma Ag Improved transdermal therapeutic system for the treatment of Parkinson's disease
DE10234673B4 (de) * 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
EP1386605A1 (en) * 2002-07-30 2004-02-04 Schwarz Pharma Ag Improved transdermal delivery system for the administration of rotigotine
ATE295726T1 (de) * 2002-12-02 2005-06-15 Sanol Arznei Schwarz Gmbh Verabreichung von rotigotine zur behandlung der parkinson'schen krankheit durch iontophorese
DE10261696A1 (de) 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
US20050202073A1 (en) 2004-03-09 2005-09-15 Mylan Technologies, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US9205062B2 (en) 2004-03-09 2015-12-08 Mylan Pharmaceuticals, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
WO2006082728A1 (ja) * 2005-02-04 2006-08-10 Hisamitsu Pharmaceutical Co., Inc. 経皮吸収貼付剤
DE102006026060B4 (de) * 2006-01-12 2013-01-31 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme
JP5190358B2 (ja) * 2006-02-28 2013-04-24 久光製薬株式会社 経皮吸収型製剤
EP3067050A1 (en) 2015-03-13 2016-09-14 Acino AG Transdermal therapeutic system with an overtape comprising two adhesive layers
EA202192644A1 (ru) * 2019-03-28 2021-12-14 Пк Мед Многокомпонентный термопластичный продукт

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151271A (en) * 1981-08-27 1992-09-29 Nitti Electric Industrial Co., Ltd. Pressure-sensitively adhering composite medicinal preparation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57116011A (en) * 1981-01-08 1982-07-19 Nitto Electric Ind Co Ltd Pharmaceutical preparation
JPS6059209B2 (ja) * 1981-08-27 1985-12-24 日東電工株式会社 複合製剤
JPS6059208B2 (ja) * 1981-08-27 1985-12-24 日東電工株式会社 複合製剤
DE3347277A1 (de) * 1983-12-28 1985-07-11 Bayer Ag, 5090 Leverkusen Wirkstoffabgabesysteme
JPS61502760A (ja) 1984-07-24 1986-11-27 キイ・フア−マシユ−テイカルズ・インコ−ポレイテツド 粘着性経皮投与層
DE3525767A1 (de) 1985-07-19 1987-01-22 Boehringer Ingelheim Kg Pharmazeutische zubereitung mit kontrollierter und verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
JPS6229003A (ja) * 1985-07-30 1987-02-07 株式会社トキメック 背面反射式光拡散装置
US5023084A (en) * 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
JPH0818975B2 (ja) * 1987-06-08 1996-02-28 日東電工株式会社 疾患治療用貼付剤
JP2688062B2 (ja) * 1988-06-20 1997-12-08 積水化学工業株式会社 医療用貼付部材
JP2690112B2 (ja) * 1988-09-14 1997-12-10 積水化学工業株式会社 医療用貼付剤
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
JPH04234317A (ja) * 1990-12-28 1992-08-24 Sekisui Chem Co Ltd 貼付剤の製造方法
US5580573A (en) * 1991-02-01 1996-12-03 E. R. Squibb And Sons, Inc. Temperature activated controlled release
US5656297A (en) * 1992-03-12 1997-08-12 Alkermes Controlled Therapeutics, Incorporated Modulated release from biocompatible polymers
CA2200060A1 (en) * 1994-09-16 1996-03-21 Jesse C. Ercillo Multi-layer pressure-sensitive adhesive construction
WO1996022084A2 (en) * 1995-01-19 1996-07-25 Cygnus, Inc. Polymer adhesive formulation containing sorbent particles
US6063838A (en) * 1995-02-16 2000-05-16 3M Innovative Properties Company Blended pressure-sensitive adhesives
ES2127711T1 (es) 1996-12-10 1999-05-01 Rotta Res Bv Sistema de administracion transdermal de farmacos para el tratamiento de enfermedades del corazon.
DE19706824C1 (de) * 1997-02-21 1998-03-26 Lohmann Therapie Syst Lts Transdermales oder topisches Plastersystem mit Polyacrylatmatrix mit verbesserten physikalischen Eigenschaften
DE19804604A1 (de) * 1998-02-06 1999-08-12 Beiersdorf Ag Vorrichtung zur Freigabe von Stoffen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151271A (en) * 1981-08-27 1992-09-29 Nitti Electric Industrial Co., Ltd. Pressure-sensitively adhering composite medicinal preparation

Also Published As

Publication number Publication date
KR20010080321A (ko) 2001-08-22
EP1143939B1 (de) 2008-08-13
WO2001013899A3 (de) 2001-08-30
DE19940238A1 (de) 2001-03-01
JP2003507417A (ja) 2003-02-25
EP1143939A2 (de) 2001-10-17
US20050136101A1 (en) 2005-06-23
DE50015307D1 (de) 2008-09-25
AR025390A1 (es) 2002-11-27
ATE404182T1 (de) 2008-08-15
AU6995700A (en) 2001-03-19
ES2312361T3 (es) 2009-03-01
WO2001013899A2 (de) 2001-03-01
US7279178B1 (en) 2007-10-09
US7335378B2 (en) 2008-02-26

Similar Documents

Publication Publication Date Title
KR100701212B1 (ko) 활성성분함유 피부부착 치료 시스템
CA2160775C (en) Transdermal therapeutic system containing estradiol
AU2016381351B2 (en) Systems and methods for long term transdermal administration
KR100374087B1 (ko) 에스트라디올투과증강제
RU2177311C2 (ru) Трансдермальный пластырь для введения 17-деацетилноргестимата отдельно или в сочетании с эстрогеном
US6162456A (en) Adhesive transdermal drug delivery matrix of a physical blend of hydrophilic and hydrophobic polymers
WO2001066095A1 (fr) Timbre extensible
JP3132837B2 (ja) 医療用粘着剤
JPH09291028A (ja) 貼付剤
JP3554573B2 (ja) アスピリン含有経皮吸収製剤
JPH10316559A (ja) 貼付剤
CN100467020C (zh) 包含支气管扩张剂的基质型贴剂
CN113194933A (zh) 具有扩散屏障的透皮治疗系统
JP3090713B2 (ja) 医療用粘着剤
JP4617069B2 (ja) 貼付剤
KR20070002035A (ko) 피부 적용을 위한 의료용 반창고
JP2006225319A (ja) 貼付製剤
CN121818581A (zh) 含利多卡因的透皮贴剂及其制备方法和用途
JPH05279251A (ja) 透湿性支持体を用いた貼付剤
HK40058438A (en) Transdermal therapeutic system with diffusion barrier
JPH03120213A (ja) 経皮吸収製剤
JPH05294832A (ja) 経皮吸収貼付剤
HK1026362A1 (en) Transdermal or topical plaster system with a polyacrylate matrix with improved physical properties
HK1026362B (zh) 改进物理特性的带有聚丙烯酸酯基质的经皮或者表皮粘膏系统
JPH01299214A (ja) 貼付剤

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20010424

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20040922

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20060214

Patent event code: PE09021S01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20060510

Patent event code: PE09021S01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20061122

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20070223

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20070322

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20070323

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20100316

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20110314

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 20120312

Start annual number: 6

End annual number: 6

FPAY Annual fee payment

Payment date: 20130315

Year of fee payment: 7

PR1001 Payment of annual fee

Payment date: 20130315

Start annual number: 7

End annual number: 7

FPAY Annual fee payment

Payment date: 20140314

Year of fee payment: 8

PR1001 Payment of annual fee

Payment date: 20140314

Start annual number: 8

End annual number: 8

FPAY Annual fee payment

Payment date: 20150313

Year of fee payment: 9

PR1001 Payment of annual fee

Payment date: 20150313

Start annual number: 9

End annual number: 9

FPAY Annual fee payment

Payment date: 20160317

Year of fee payment: 10

PR1001 Payment of annual fee

Payment date: 20160317

Start annual number: 10

End annual number: 10

FPAY Annual fee payment

Payment date: 20170310

Year of fee payment: 11

PR1001 Payment of annual fee

Payment date: 20170310

Start annual number: 11

End annual number: 11

FPAY Annual fee payment

Payment date: 20180309

Year of fee payment: 12

PR1001 Payment of annual fee

Payment date: 20180309

Start annual number: 12

End annual number: 12

PC1801 Expiration of term

Termination date: 20210214

Termination category: Expiration of duration