KR100672950B1 - 허혈성 심질환 예방 또는 치료용 석창포 추출물 및 이를함유하는 약학적 조성물과 건강 식품 - Google Patents
허혈성 심질환 예방 또는 치료용 석창포 추출물 및 이를함유하는 약학적 조성물과 건강 식품 Download PDFInfo
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- KR100672950B1 KR100672950B1 KR1020040042189A KR20040042189A KR100672950B1 KR 100672950 B1 KR100672950 B1 KR 100672950B1 KR 1020040042189 A KR1020040042189 A KR 1020040042189A KR 20040042189 A KR20040042189 A KR 20040042189A KR 100672950 B1 KR100672950 B1 KR 100672950B1
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- heart disease
- ischemic heart
- seokchangpo
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Abstract
Description
대조군 | 실험군 | |||||||
시간 (min) | 혈압 (mmHg) | 대동맥 박출량 (㎖/min) | 관상동맥 관류량 (㎖/min) | 심장 박출량 (㎖/min) | 혈압 (mmHg) | 대동맥 박출량 (㎖/min) | 관상동맥 관류량 (㎖/min) | 심장 박출량 (㎖/min) |
20 | 93.70 ±1.00 | 70.30 ±1.17 | 22.90 ±0.82 | 92.20 ±1.47 | 92.10 ±1.23 | 70.00 ±2.50 | 22.33 ±2.33 | 92.33 ±2.41 |
25 | 93.50 ±0.87 | 67.00 ±1.32 | 23.30 ±0.75 | 90.30 ±1.51 | 93.30 ±0.56 | 68.90 ±2.03 | 23.00 ±1.45 | 91.90 ±2.01 |
30 | 93.80 ±1.14 | 66.70 ±0.94 | 22.00 ±0.97 | 88.70 ±1.28 | 93.03 ±0.54 | 71.00 ±1.80 | 21.67 ±0.90 | 92.67 ±1.78 |
35 | 92.30 ±1.18 | 66.20 ±1.22 | 22.80 ±0.39 | 89.00 ±1.26 | 93.10 ±0.72 | 70.05 ±2.40 | 23.63 ±0.88 | 93.68 ±2.38 |
70 | 64.30 ±1.11 | 34.70 ±1.01 | 13.80 ±0.53 | 48.50 ±1.11 | 82.00 ±1.15 | 39.33 ±2.96 | 18.90 * ±2.31 | 58.23 ** ±2.96 |
80 | 63.70 ±1.16 | 34.90 ±1.15 | 13.90 ±0.81 | 48.80 ±1.31 | 80.80 ** ±1.48 | 50.67 ** ±2.73 | 19.70 * ±1.76 | 70.37 ** ±2.71 |
90 | 59.00 ±1.30 | 32.40 ±1.38 | 12.70 ±0.72 | 45.10 ±1.64 | 79.80 ** ±1.46 | 51.00 ** ±4.36 | 18.01 * ±1.80 | 69.01 ** ±4.32 |
100 | 58.60 ±1.46 | 31.70 ±1.12 | 13.40 ±1.14 | 45.10 ±1.68 | 79.30 ** ±1.40 | 51.33 ** ±3.19 | 20.80 ** ±2.08 | 72.13 ** ±3.18 |
110 | 54.10 ±1.12 | 32.40 ±1.40 | 12.90 ±0.67 | 45.30 ±1.61 | 79.20 ** ±1.45 | 48.67 ** ±2.33 | 19.60 ** ±0.70 | 68.27 ** ±2.31 |
120 | 51.60 ±1.01 | 31.70 ±1.64 | 13.80 ±0.88 | 45.50 ±1.55 | 77.60 ** ±1.89 | 50.80 ** ±2.03 | 21.50 ** ±0.90 | 72.30 ** ±2.02 |
① * : 대조군과 비교하여 확률(P)〈 0.05 ② **: 대조군과 비교하여 확률(P)〈0.01 ③ 각 수치는 평균±표준오차임 |
대조군 (단위: %) | 실험군 (단위: %) | ||||||||
시간 (min) | 혈압 | 대동맥 박출량 | 관상동맥 관류량 | 심장 박출량 | 혈압 | 대동맥 박출량 | 관상동맥 관류량 | 심장 박출량 | |
허혈성쇼크 전 | ~ 20 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 |
허혈성쇼크 후 | 10 | 68.4 | 52.0 | 61.1 | 53.8 | 87.7 | 55.0 | 83.1 | 62.3 |
20 | 68.1 | 52.3 | 62.5 | 54.1 | 85.6 | 70.9 | 86.6 | 75.2 | |
30 | 63.1 | 48.6 | 57.1 | 50.0 | 85.3 | 71.4 | 79.2 | 73.8 | |
40 | 62.7 | 47.5 | 60.3 | 50.0 | 84.8 | 71.8 | 91.5 | 77.1 | |
50 | 58.0 | 48.6 | 58.0 | 50.2 | 84.7 | 68.1 | 86.2 | 73.0 | |
60 | 55.2 | 47.5 | 62.1 | 50.5 | 83.0 | 71.1 | 94.6 | 77.3 |
Claims (5)
- 석창포를 물 또는 에탄올 수용액으로 추출하여 제조하는 허혈성 심질환 예방 또는 치료용 석창포(Acous Gramineus Soland) 추출물.
- 삭제
- 삭제
- 제1항의 석창포 추출물을 유효성분으로 함유하는 허혈성 심질환 예방 또는 치료용 약학적 조성물.
- 제1항의 석창포 추출물을 유효성분으로 함유하는 허혈성 심질환 예방 또는 개선용 건강 식품.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020040042189A KR100672950B1 (ko) | 2004-06-09 | 2004-06-09 | 허혈성 심질환 예방 또는 치료용 석창포 추출물 및 이를함유하는 약학적 조성물과 건강 식품 |
AU2005251639A AU2005251639A1 (en) | 2004-06-09 | 2005-06-09 | Acorus gramineus Soland extract for preventing and treating ischemic heart disease and pharmaceutical composition and health food containing the same |
JP2007527008A JP2008501788A (ja) | 2004-06-09 | 2005-06-09 | 虚血性心疾患予防又は治療用石菖蒲抽出物及びこれを含有する薬学的組成物と健康食品 |
US11/570,328 US20080038380A1 (en) | 2004-06-09 | 2005-06-09 | Acorus Gramineus Soland Extract for Preventing and Treating Ischemic Heart Disease and Pharmaceutical Composition and Health Food Containing the Same |
EP05765043A EP1793690A4 (en) | 2004-06-09 | 2005-06-09 | EXTRACT OF ACORUS GRAMINEUS SOLAND FOR THE PREVENTION AND TREATMENT OF HERZISCHÄMIE AND PHARMACEUTICAL COMPOSITION AND DIETARY FOOD CONTAINING THIS |
PCT/KR2005/001738 WO2005120531A1 (en) | 2004-06-09 | 2005-06-09 | Acorus gramineus soland extract for preventing and treating ischemic heart disease and pharmaceutical composition and health food containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020040042189A KR100672950B1 (ko) | 2004-06-09 | 2004-06-09 | 허혈성 심질환 예방 또는 치료용 석창포 추출물 및 이를함유하는 약학적 조성물과 건강 식품 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20050117024A KR20050117024A (ko) | 2005-12-14 |
KR100672950B1 true KR100672950B1 (ko) | 2007-01-22 |
Family
ID=35502822
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Application Number | Title | Priority Date | Filing Date |
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KR1020040042189A KR100672950B1 (ko) | 2004-06-09 | 2004-06-09 | 허혈성 심질환 예방 또는 치료용 석창포 추출물 및 이를함유하는 약학적 조성물과 건강 식품 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20080038380A1 (ko) |
EP (1) | EP1793690A4 (ko) |
JP (1) | JP2008501788A (ko) |
KR (1) | KR100672950B1 (ko) |
AU (1) | AU2005251639A1 (ko) |
WO (1) | WO2005120531A1 (ko) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101127073B1 (ko) * | 2008-10-20 | 2012-03-23 | 연세대학교 산학협력단 | 창포 정유를 포함하는 혈관 평활근 세포 이상 증식성 질환의 예방 또는 치료용 조성물 |
CN102526383A (zh) * | 2011-12-27 | 2012-07-04 | 浙江中医药大学 | 一种石菖蒲提取物及制备方法和应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1147950A (zh) * | 1996-04-30 | 1997-04-23 | 郭约翰 | 防治脑血管病的口服液 |
CN1147952A (zh) * | 1996-09-09 | 1997-04-23 | 王全江 | 冠心康茶及制作工艺 |
CN1057223C (zh) * | 1997-04-08 | 2000-10-11 | 刘志恒 | 一种心脑康复药酒的制作方法 |
CN1202364A (zh) * | 1997-06-13 | 1998-12-23 | 湖南中医学院第一附属医院 | 缓解心绞痛油剂 |
KR20000033287A (ko) * | 1998-11-20 | 2000-06-15 | 신상국 | 흉통 견갑통 심장질환 치료용 한방음료, 한방환 조성물 및 그제조법 |
KR20010069034A (ko) * | 2000-01-11 | 2001-07-23 | 박길래 | 치매개선 및 뇌기능활성화용 한방생약제의 식품음료조성물 |
JP4880816B2 (ja) * | 2000-12-15 | 2012-02-22 | 株式会社ヤクルト本社 | 皮膚老化防止剤 |
KR20030029563A (ko) * | 2003-03-11 | 2003-04-14 | 김대곤 | 함초,석창포 를 주제로 한 건강식품 |
KR20030044967A (ko) * | 2003-05-12 | 2003-06-09 | 김대곤 | 조릿대.석창포(총명탄)를주제로한 건강식품 |
-
2004
- 2004-06-09 KR KR1020040042189A patent/KR100672950B1/ko active IP Right Grant
-
2005
- 2005-06-09 US US11/570,328 patent/US20080038380A1/en not_active Abandoned
- 2005-06-09 EP EP05765043A patent/EP1793690A4/en not_active Withdrawn
- 2005-06-09 WO PCT/KR2005/001738 patent/WO2005120531A1/en active Application Filing
- 2005-06-09 AU AU2005251639A patent/AU2005251639A1/en not_active Abandoned
- 2005-06-09 JP JP2007527008A patent/JP2008501788A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2005251639A1 (en) | 2005-12-22 |
KR20050117024A (ko) | 2005-12-14 |
EP1793690A1 (en) | 2007-06-13 |
JP2008501788A (ja) | 2008-01-24 |
US20080038380A1 (en) | 2008-02-14 |
WO2005120531A1 (en) | 2005-12-22 |
EP1793690A4 (en) | 2009-07-29 |
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