KR100657777B1 - 연속 포맷 고처리량 스크리닝 - Google Patents

연속 포맷 고처리량 스크리닝 Download PDF

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Publication number
KR100657777B1
KR100657777B1 KR1020007006322A KR20007006322A KR100657777B1 KR 100657777 B1 KR100657777 B1 KR 100657777B1 KR 1020007006322 A KR1020007006322 A KR 1020007006322A KR 20007006322 A KR20007006322 A KR 20007006322A KR 100657777 B1 KR100657777 B1 KR 100657777B1
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matrix
assay
delete delete
gel
reagent
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KR20010024709A (ko
Inventor
뷰텔브루스에이
슐덱마크이
부어배치마틴제이
번즈데이비드제이
조지프메리케이
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아보트 러보러터리즈
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Assigned to 애브비 인코포레이티드 reassignment 애브비 인코포레이티드 권리의 전부이전등록 Assignors: 아보트 러보러터리즈
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00527Sheets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/0061The surface being organic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614Delimitation of the attachment areas
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623Immobilisation or binding
    • B01J2219/0063Other, e.g. van der Waals forces, hydrogen bonding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00639Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B01J2219/00641Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00702Processes involving means for analysing and characterising the products
    • B01J2219/00707Processes involving means for analysing and characterising the products separated from the reactor apparatus

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Paper (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Image Processing (AREA)
KR1020007006322A 1997-12-12 1998-12-11 연속 포맷 고처리량 스크리닝 Expired - Fee Related KR100657777B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/990,168 US5976813A (en) 1997-12-12 1997-12-12 Continuous format high throughput screening
US08/990,168 1997-12-12
PCT/US1998/026465 WO1999030154A2 (en) 1997-12-12 1998-12-11 Continuous format high throughput screening

Publications (2)

Publication Number Publication Date
KR20010024709A KR20010024709A (ko) 2001-03-26
KR100657777B1 true KR100657777B1 (ko) 2006-12-15

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KR1020007006322A Expired - Fee Related KR100657777B1 (ko) 1997-12-12 1998-12-11 연속 포맷 고처리량 스크리닝

Country Status (25)

Country Link
US (1) US5976813A (https=)
EP (1) EP1038179B1 (https=)
JP (1) JP4558197B2 (https=)
KR (1) KR100657777B1 (https=)
CN (2) CN101256187A (https=)
AT (1) ATE336001T1 (https=)
AU (1) AU759538B2 (https=)
BG (1) BG65264B1 (https=)
BR (1) BR9815059A (https=)
CA (1) CA2310684C (https=)
CY (1) CY1106220T1 (https=)
CZ (1) CZ299740B6 (https=)
DE (1) DE69835537T2 (https=)
DK (1) DK1038179T3 (https=)
ES (1) ES2270539T3 (https=)
HU (1) HU228578B1 (https=)
IL (1) IL135793A (https=)
NO (1) NO326662B1 (https=)
NZ (1) NZ504112A (https=)
PL (1) PL194813B1 (https=)
PT (1) PT1038179E (https=)
SK (1) SK286095B6 (https=)
TR (1) TR200001647T2 (https=)
TW (1) TW555967B (https=)
WO (1) WO1999030154A2 (https=)

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HK1032996A1 (en) 2001-08-10
EP1038179B1 (en) 2006-08-09
CN101256187A (zh) 2008-09-03
KR20010024709A (ko) 2001-03-26
PL341655A1 (en) 2001-04-23
JP4558197B2 (ja) 2010-10-06
IL135793A0 (en) 2001-05-20
NO20002079L (no) 2000-06-09
SK286095B6 (sk) 2008-03-05
HUP0100207A2 (hu) 2001-06-28
CA2310684A1 (en) 1999-06-17
AU1821699A (en) 1999-06-28
JP2001526390A (ja) 2001-12-18
CZ20002078A3 (cs) 2000-09-13
NO20002079D0 (no) 2000-04-19
WO1999030154A2 (en) 1999-06-17
HUP0100207A3 (en) 2003-08-28
WO1999030154A3 (en) 1999-08-12
BR9815059A (pt) 2007-05-22
DE69835537D1 (de) 2006-09-21
BG65264B1 (bg) 2007-10-31
PT1038179E (pt) 2006-12-29
PL194813B1 (pl) 2007-07-31
ATE336001T1 (de) 2006-09-15
CY1106220T1 (el) 2011-06-08
CA2310684C (en) 2011-05-10
TW555967B (en) 2003-10-01
AU759538B2 (en) 2003-04-17
CN1281552A (zh) 2001-01-24
SK8362000A3 (en) 2000-10-09
ES2270539T3 (es) 2007-04-01
DE69835537T2 (de) 2007-08-09
IL135793A (en) 2005-09-25
NO326662B1 (no) 2009-01-26
BG104564A (en) 2001-04-30
HU228578B1 (en) 2013-04-29
NZ504112A (en) 2002-11-26
EP1038179A2 (en) 2000-09-27
DK1038179T3 (da) 2006-11-20
US5976813A (en) 1999-11-02
CZ299740B6 (cs) 2008-11-05
TR200001647T2 (tr) 2001-06-21

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