KR100580642B1 - 표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이 - Google Patents

표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이 Download PDF

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KR100580642B1
KR100580642B1 KR1020040001963A KR20040001963A KR100580642B1 KR 100580642 B1 KR100580642 B1 KR 100580642B1 KR 1020040001963 A KR1020040001963 A KR 1020040001963A KR 20040001963 A KR20040001963 A KR 20040001963A KR 100580642 B1 KR100580642 B1 KR 100580642B1
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South Korea
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group
dianhydride
anhydride
biomolecule
solid support
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Korean (ko)
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KR20050073856A (ko
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황규연
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삼성전자주식회사
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Priority to KR1020040001963A priority Critical patent/KR100580642B1/ko
Priority to US11/028,822 priority patent/US7195924B2/en
Priority to DE602005000189T priority patent/DE602005000189T2/de
Priority to EP05000285A priority patent/EP1553415B1/en
Priority to CNB2005100044744A priority patent/CN100392099C/zh
Priority to JP2005005638A priority patent/JP4045276B2/ja
Publication of KR20050073856A publication Critical patent/KR20050073856A/ko
Application granted granted Critical
Publication of KR100580642B1 publication Critical patent/KR100580642B1/ko
Priority to US11/678,275 priority patent/US20070141556A1/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020040001963A 2004-01-12 2004-01-12 표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이 Expired - Fee Related KR100580642B1 (ko)

Priority Applications (7)

Application Number Priority Date Filing Date Title
KR1020040001963A KR100580642B1 (ko) 2004-01-12 2004-01-12 표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이
US11/028,822 US7195924B2 (en) 2004-01-12 2005-01-04 Method for immobilizing a biomolecule on a solid substrate at a high density by using the substrate having an activated carboxyl group on a surface thereof and microarray produced using the method
EP05000285A EP1553415B1 (en) 2004-01-12 2005-01-07 Method for immobilizing a biomolecule on a solid substrate at a high density by using the substrate having an activated carboxyl group on a surface thereof and microarray produced using the method
DE602005000189T DE602005000189T2 (de) 2004-01-12 2005-01-07 Verwendung eines Trägers mit einer aktivierten Carboxylgruppe an der Oberfläche in einem Verfahren zur hochdichten Immobilisierung von Biomolekülen auf besagtem Träger und ein Microarray welches über dieses Verfahren hergestellt wurde
CNB2005100044744A CN100392099C (zh) 2004-01-12 2005-01-12 将生物分子高密度固定到表面具有活化羧基的固体基质上的方法及用该方法制备的微阵列
JP2005005638A JP4045276B2 (ja) 2004-01-12 2005-01-12 表面に活性化されたカルボキシル基を有する固体基板を利用して生体分子を前記固体基板上に高密度で固定化する方法及びそれによって製造されるマイクロアレイ
US11/678,275 US20070141556A1 (en) 2004-01-12 2007-02-23 Method for immobilizing a biomolecule on a solid substrate at a high density by using the substrate having an active carboxyl group on a surface thereof and microarray produced using the method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020040001963A KR100580642B1 (ko) 2004-01-12 2004-01-12 표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이

Publications (2)

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KR20050073856A KR20050073856A (ko) 2005-07-18
KR100580642B1 true KR100580642B1 (ko) 2006-05-16

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KR1020040001963A Expired - Fee Related KR100580642B1 (ko) 2004-01-12 2004-01-12 표면에 활성화된 카르복실기를 갖는 기판을 이용하여 생물분자를 고체 기판상에 고밀도로 고정화하는 방법 및 그에 의하여 제조되는 마이크로어레이

Country Status (6)

Country Link
US (2) US7195924B2 (https=)
EP (1) EP1553415B1 (https=)
JP (1) JP4045276B2 (https=)
KR (1) KR100580642B1 (https=)
CN (1) CN100392099C (https=)
DE (1) DE602005000189T2 (https=)

Cited By (1)

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KR101438817B1 (ko) * 2007-03-22 2014-09-05 신에쓰 가가꾸 고교 가부시끼가이샤 마이크로어레이 제작용 기판의 제조 방법

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KR100657907B1 (ko) * 2004-11-03 2006-12-14 삼성전자주식회사 신규한 링커 화합물, 상기 화합물이 코팅되어 있는 기판,상기 화합물을 이용하여 마이크로어레이를 제조하는 방법및 그에 의하여 제조된 마이크로어레이
GB2420849B (en) * 2004-12-02 2007-06-27 Schlumberger Holdings Optical pH sensor
KR100738083B1 (ko) * 2005-12-20 2007-07-12 삼성전자주식회사 마이크로어레이용 기판 및 그의 제조방법
KR100829574B1 (ko) 2006-01-03 2008-05-14 삼성전자주식회사 마이크로어레이용 기판, 그 마이크로어레이용 기판을이용하여 생분자를 분석하는 방법, 및 그 마이크로어레이용기판을 포함하는 랩온어칩
US7493199B2 (en) * 2006-10-17 2009-02-17 Trw Automotive U.S. Llc Method of controlling a roll control system for improved vehicle dynamic control
KR100843147B1 (ko) * 2007-02-12 2008-07-03 삼성전자주식회사 올리고머 프로브 어레이용 기판과 올리고머 프로브 어레이및 이들의 제조 방법
JP5344835B2 (ja) * 2008-03-24 2013-11-20 富士フイルム株式会社 固定化方法、生理活性物質固定化担体及び固定用担体
JP5388462B2 (ja) * 2008-03-24 2014-01-15 富士フイルム株式会社 担体及びその製造方法
EP2270507A4 (en) * 2008-03-24 2013-02-27 Fujifilm Corp IMMOBILIZING METHOD, PHYSIOLOGICALLY ACTIVE SUBSTANCE SUPPORTING MEDIUM, HOLDING MEDIUM, SUPPORT AND SUPPORT MANUFACTURING METHOD
DE102010049807A1 (de) 2010-10-27 2012-05-03 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Immobilisierung mindestens einer Substanz auf Oberflächen
JP5462919B2 (ja) * 2011-10-31 2014-04-02 アークレイ株式会社 基材の修飾方法
CN104027852B (zh) * 2014-06-26 2015-09-23 淮阴工学院 生物材料的表面改性方法
KR101603602B1 (ko) 2014-07-09 2016-03-16 한국원자력연구원 방사선 조사를 이용한 폴리도파민 코팅 고분자 기질 및 이의 제조 방법
CN105854962B (zh) * 2016-03-28 2018-01-19 北京瑞联安科技有限公司 一种生物识别分子固定到生物芯片的方法
JP6931181B2 (ja) * 2016-12-20 2021-09-01 東洋製罐グループホールディングス株式会社 生体関連分子固定化用担体
US11312831B2 (en) 2016-11-18 2022-04-26 Toyo Seikan Group Holdings, Ltd. Carrier for bio-related molecule immobilization
JP2018078864A (ja) * 2016-11-18 2018-05-24 東洋製罐グループホールディングス株式会社 生体関連分子固定化用担体

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KR101438817B1 (ko) * 2007-03-22 2014-09-05 신에쓰 가가꾸 고교 가부시끼가이샤 마이크로어레이 제작용 기판의 제조 방법

Also Published As

Publication number Publication date
DE602005000189D1 (de) 2006-12-07
US20070141556A1 (en) 2007-06-21
JP2005201901A (ja) 2005-07-28
CN100392099C (zh) 2008-06-04
EP1553415B1 (en) 2006-10-25
US20050153350A1 (en) 2005-07-14
US7195924B2 (en) 2007-03-27
DE602005000189T2 (de) 2007-02-08
CN1661114A (zh) 2005-08-31
JP4045276B2 (ja) 2008-02-13
KR20050073856A (ko) 2005-07-18
EP1553415A1 (en) 2005-07-13

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