KR100523842B1 - A cosmetic composition containing the mixture of natural plant extracts - Google Patents

Abstract

The present invention relates to a cosmetic for improving skin troubles containing a natural mixed extract, more specifically, asparagus cochinchinensis (Lour.) Merr., Kanto ( Tussilago farfara L) and kelp ( Laminaria japonica Aresch) By using it as an antibacterial, anti-inflammatory, irritant effect, whitening effect, etc., it relates to a cosmetic that can heal and improve skin troubles such as acne, allergy, erythema and the like.

Description

A cosmetic composition containing the mixture of natural plant extracts

The present invention relates to a cosmetic for improving skin troubles containing a natural mixed extract, more specifically, asparagus cochinchinensis (Lour.) Merr., Kanto ( Tussilago farfara L) and kelp ( Laminaria japonica Aresch) By using it as an antimicrobial, anti-inflammatory, irritant, whitening effect, etc., it relates to a cosmetic that can heal and improve skin troubles such as acne, allergy, erythema and the like.

Inflammation is a series of defenses aimed at minimizing the response and restoring the damaged area when a cell or tissue is damaged by any cause. Physical factors, including trauma, injuries, frostbite, and radiation, can cause inflammation. There are chemical factors caused by chemicals such as peracids, immunological factors caused by antibody reactions, and they can also be caused by vascular or hormonal imbalances. Anti-inflammatory drugs are called anti-inflammatory agents that work to eliminate inflammation, reduce biologic reactions and symptoms to eliminate inflammation. The substances used for anti-inflammatory purposes to date are nonsteroidal flufenamic acid, ibuprofen, benzydamine, indomethacin, and indonethacin, and prednisolone as a steroid system. ), Dexamethasone (dexamethasone) [Kim Chang-jong, Pathophysiology, Hallym Co., p61-69, 1988], allantoin, azulene, ε-aminochiproic acid, hydrocortisone, licoriceic acid and its derivatives (β- Glychilechin acid, Glychilechin acid derivatives) and the like are known to be effective in anti-inflammatory [Ministry of Justice, Department of New Cosmetics, Namsan Sugar, p162, 1993].

Inflammatory response is characterized by pain, fever, redness, swelling, and loss of function due to external stimuli. Histologically, the periphery of small arteries, capillaries, and venous veins and dilatation with increased blood flow and plasma-containing protein Complex symptoms including exudation, migration of leukocytes to inflammatory sites, etc. are observed. Anti-inflammatory is a series of actions that prevent the destruction of tissues from external stimuli.

Various microorganisms exist in human skin. These microorganisms cause various skin diseases. Staphylococcus aureus , which causes purulent skin, includes Staphylococcus epidermis, Propionibacterium acnes, and Pity ovale. Decomposes sebum or sweat secreted on the skin to produce odors, and the decomposition products irritate and irritate the skin. In particular, acne bacteria ( Propionibacterium acnes ) is a fatty acid degrading enzyme using lipase (lipase) to break down the sebum to produce free fatty acids. These free fatty acids not only irritate the skin but also cause inflammatory lesions such as papules, pustules and nodules, which are red rashes found in acne.

Skin fungi (dermatophytes) produces a superficial fungus invades the stratum corneum of the skin and hair. Skin filaments that cause superficial mycosis include Microsporum , Trichophyton , and Epidermophyton , and the fungi represent ringworm. Candida albicans also causes cutaneous candidiasis and chronic mucosal candidiasis. These fungi represent superficial mycosis, in which the fungus parasitic in the keratinous tissue of the skin and multiplies and causes lesions. Another causative agent of granulomatous lesions in skin and subcutaneous tissue is Sporotrix schenckii .

It can be seen that the development of a cosmetic having excellent antibacterial and anti-inflammatory effects on the bacteria that may be present in such skin.

One of the herbal medicines used in the present invention, Kwanhwahwa (Tussilago farfara L.) is a perennial herb of the Asteraceae, which is about 0.1 to 0.3 m in height, also called assimilation. It is not found in Korea and is produced in Gansu, Shanxi, and Shaanxi in China. The main components of the flower are paradiol, L-phytosterol, arnidiol, rufeoltriterpenoids, taraxanthin, stigmagsterin, phytosterin, heptacozan and tannins, and the leaves have mucus 5-10%. (Galactozan, pentozan), phytosterin, glutathione, malic acid, grape acid, saponin, carotenoids, ascorbic acid, polysaccharides inulin and flavonoids, tannins. The main pharmacological action is that flower decoction is known as expectorant, coughing, and anti-inflammatory effects of experimental animals. In herbal medicine, it is used as a cough sputum medicine and anti-inflammatory agent, such as bronchial asthma, laryngitis, bronchiectasis, pneumonia, bronchitis, gastrointestinal catarrh, inflammation of the kidneys and urethra. Korean Medical Dictionary, Kyung Hee University Press, 1999, Seoul, 508 ~ 510].

Asparagus cochinchinensis (Lour.) Merr. Is a perennial herb belonging to the Nariaceae family that grows near the seashore or in the marshland of Sanya. . Astronomical dong is sweet and bitter, has a strong temper, and works on menopause and nerves to stop the coughing, soaking down the fever and stop coughing.In pharmacological experiments, the ingredient is asparagine, sputum, coughing, anti-cancer, urinating. Bet. Its main components include saponin, flavonoid and asparagine [Astronomical Environment and Growth Characteristics of Astronomical Astronomical Sites, Herbal Medicine Fields, 11 (3) 212 ~ 215, (2003)].

Kelp (Laminaria japonica Aresch) is a genus of seaweed kelp and is a large sea horse. It is a Hanhaeseong plant distributed on the coast of the Handae and Bohan, and it is known to grow in the northeastern coast, Hamnam and Hambuk, north of Wonsan, and the coast, Kamchatka, north of Hokkaido and Tohoku in Japan. It is distributed in the Pacific coast such as Sakhalin. In addition to various pigments such as carotene, xanthophylls, and chlorophyll, kelp contains a large amount of carbohydrates, such as manit and laminarin, and alginic acid, which are components of cell walls. Amino acids such as vitamin B2 and glutamic acid. These ingredients vary depending on the type of kelp, but they are usually about 16% water, 7% protein, 1.5% fat, 49% carbohydrates, and 26.5% inorganic salts. 20% of the carbohydrates are fibrin and the rest are polysaccharides such as alginic acid and laminarin. to be. In particular, since it contains a large amount of inorganic salts, such as iodine, potassium and calcium, it is preferable to feed kelp little by little to supply inorganic salts. The amino acid called laminin in kelp is effective in lowering blood pressure.

Although the extract of each of the astronomical dong, Kwanhwa, kelp is already known to have an antimicrobial effect and an anti-inflammatory effect, the effect is not so excellent that it is difficult to apply to cosmetics.

Thus, the present inventors have studied in order to solve the above problems, as a result of using a certain ratio mixed extract of astronomical dong, Kwandonghwa, kelp, compared to conventional herbal medicines to check the effects of superior antibacterial, anti-inflammatory, irritation, whitening, etc. The present invention has been completed by developing a cosmetic for improving trouble.

Therefore, an object of the present invention is to provide a cosmetic for improving skin troubles containing astronomical dong, Kanto and kelp mixed extract.

The present invention is characterized by a cosmetic for improving skin problems containing astronomical dong, Kanto and kelp mixed extract.

The present invention will be described in more detail as follows.

The present invention is a mixture of asparagus cochinchinensis (Lour.) Merr., Kwanhwa ( Tussilago farfara L) and kelp ( Laminaria japonica Aresch) by using a certain ratio exhibits excellent effects such as antibacterial, anti-inflammatory, irritant, whitening effect, etc. The present invention relates to cosmetics capable of healing and improving skin troubles such as acne and allergic erythema.

Mixing astronomical dong, Kanto and kelp in a weight ratio of 0.5 to 3: 0.5 to 3: 0.5 to 3, an organic solvent selected from ethanol, methanol, propanol, butanol, glycerin, propylene glycol and butylene glycol, or a mixed solvent of the organic solvent and water Extract by adding 1 to 20 times by volume. At this time, more preferably, astronomical dong, Kanto and kelp are mixed in a weight ratio of 0.8 to 2: 0.8 to 2: 0.8 to 2. At this time, it is not preferable because there is a problem that the antibacterial, anti-inflammatory effect falls outside the above range. The said materials may be extracted, respectively, and may be mixed and extracted. As the extraction method, a method of extracting by heating at 40 to 100 ° C. for 2 to 20 hours or extracting the active ingredient at 4 to 40 ° C. for 2 to 20 hours while a cooling condenser is installed to prevent the solvent from evaporating may be used. Can be.

The mixed extract thus prepared showed an excellent antimicrobial effect of 3 to 10 times compared to the single extract, and has an excellent anti-inflammatory effect of 2 to 8 times compared to the single extract, and also has a stimulating alleviation effect. It can be used to heal or improve skin problems such as allergies, erythema, etc., and it is expected to be more useful for people with chemical-sensitive skin because of the use of natural materials.

Meanwhile, when the mixed extract is applied to cosmetics, basic product cosmetics (cosmetics, lotions, creams, essences, cleansing foams, cleansing water, packs), body cosmetics (body lotions, body oils, body gels), color cosmetics (foundation) , Lipstick, mascara, make-up base), hair cosmetics (shampoo, rinse, hair conditioner, hair gel), etc., but preferably with a lotion (skin lotion), nutrition lotion, nutrition cream, massage cream and essence It is mix | blended in the content of 0.001- 30.0 weight% with respect to cosmetic composition.

Hereinafter, the present invention will be described in more detail based on the following examples, but the present invention is not limited thereto.

Examples 1 to 17 and Comparative Examples 1 to 6

The astronomical dong, Kwandonghwa, kelp, 70% hydrous ethanol in 10 times the amount of the raw material in the composition ratio as shown in Table 1, extracted at room temperature for 5 days with an extractor, filtered through a 400 mesh filter cloth and 0.45 ㎛ filter filtered the results are shown in the following table It described in 1.

division Raw material (* 10 ² g) Yield (kg) Solid content (g / L) Astronomical building Kanto Kelp Comparative Example 1 3 0 0 2.6 6.3 Comparative Example 2 0 3 0 2.7 5.4 Comparative Example 3 0 0 3 2.7 8.3 Comparative Example 4 One 2 0 2.4 9.3 Comparative Example 5 2 0 One 2.1 8.2 Comparative Example 6 0 One 2 2.9 7.7 Example 1 One One One 2.7 7.4 Example 2 0.8 One 1.2 2.6 6.2 Example 3 One 1.2 0.8 2.5 8.5 Example 4 1.2 0.8 One 2.7 8.6 Example 5 0.8 1.2 One 2.6 8.3 Example 6 One 0.8 1.2 2.3 8.3 Example 7 1.2 One 0.8 2.8 9.1 Example 8 0.8 0.8 1.4 2.6 9.0 Example 9 0.8 1.4 0.8 2.3 8.0 Example 10 1.4 0.8 0.8 2.7 7.6 Example 11 2 One One 3.6 7.4 Example 12 3 One One 4.5 6.5 Example 13 One 2 One 3.7 5.3 Example 14 One 3 One 4.5 6.3 Example 15 One One 2 3.7 7.2 Example 16 One One 3 4.6 6.6 Example 17 2 One 2 4.6 7.3

Examples 18-22

100 g of astronomical dong, 100 g of Kanto and 100 g of kelp were added to 3 kg using the solvent of the following Table 2, extracted at room temperature with an extractor for 5 days, filtered through a 400 mesh filter cloth and filtered through a filter of 0.45 μm, and the yield and solid content of the extract. Are listed in Table 2 below.

division menstruum Yield (kg) Solid content (g / L) Example 18 Purified water 2.7 8.2 Example 19 95% ethanol 2.6 7.6 Example 20 30% water propylene glycol 2.6 8.4 Example 21 30% water ethanol 2.7 7.2 Example 22 30% water butylene glycol 2.7 8.6

Example 23

100 g of astronomical dong, 100 g of Kanto, and 100 g of kelp are placed in 3 kg of 30% hydrous butylene glycol and heated at 80 ° C. for 3 hours with a cooling condenser installed to prevent evaporation of the solvent, followed by filtration with 400 mesh filter cloth. 0.45 μm of the filter was filtered to obtain 2.7 kg (6.8 g / l) of the extract.

Examples 24-28

The solvent of Table 3 was used and the extraction was carried out in the same manner as in Example 4, and the results are shown in Table 3 below.

division menstruum Yield (kg) Solid content (g / L) Example 24 Purified water 2.9 8.6 Example 25 95% ethanol 2.5 9.3 Example 26 30% water propylene glycol 2.6 6.5 Example 27 30% water ethanol 2.7 11.3 Example 28 30% water glycerine 2.3 2.5

Experimental Example 1: Antimicrobial Effect Experiment

The antimicrobial effect of the mixed extract Examples 1 to 21 and Comparative Examples 1 to 6 was measured as follows.

[Experimental method]

Antimicrobial experiments were measured by agar diffusion using a paper disc. Strains were inoculated with 100 ml of liquid medium and incubated at a suitable temperature for 18 to 24 hours to activate. 100 μl of the solution was inoculated into each medium (10 ⁷ to 10 ⁸ cfu / ml) and the plates were covered. Each extract was placed on a sterile disk plate surface and 20 μl of the sample was dropped. After 36 hours of incubation, the antimicrobial activity was measured by the diameter (mm) of the inhibitory rings formed around the disc.

The strain was used as the following microbial test strain.

Escherichia coli , Staphylococcus aureus , Bacillus subtilis , Candida albican and Candida albican and Propionibacterium acne were selected. It was.

Culture conditions for each strain number Strain badge Culture condition type One Candida albicans (ATCC 10259) Nutrient agar 48hrs, 37 ℃ Exhalation 2 Escherichia coli (ATCC 25922) Tripticase soy agar 48hrs, 37 ℃ Exhalation 3 Staphylococcus aureus ATCC 29737 Nutrient agar 48hrs, 37 ℃ Exhalation 4 Bacillus subtilis ATCC 6633 Nutrient agar 48hrs, 37 ℃ Exhalation 5 Propionibacterium acne ATCC 6919) Reinforced clostridial agar medium 72hrs, 37 ℃ anaerobe

division Used strain One 2 3 4 5 Comparative Example 1 - ++ - - - Comparative Example 2 + + - + - Comparative Example 3 - - - - - Comparative Example 4 + + - ++ + Comparative Example 5 - ++ ++ + + Comparative Example 6 + - - + + Example 1 ++ ++ ++ ++ ++ Example 2 ++ +++ ++ ++ ++++ Example 3 +++ + +++ ++ ++ Example 4 ++++ +++ +++ ++++ ++++ Example 5 +++ ++ ++ ++ ++ Example 6 ++ ++++ +++ ++ +++ Example 7 +++ +++ +++ ++ +++ Example 8 ++ +++ ++ ++ +++ Example 9 +++ +++ +++ ++ ++ Example 10 ++ + ++++ ++ +++ Example 11 ++ +++ +++ ++ +++ Example 12 ++++ +++ +++ ++ +++ Example 13 +++ +++ ++++ ++ ++++ Example 14 +++ + +++ ++++ +++ Example 15 ++++ ++ +++ ++ +++ Example 16 ++++ +++ +++ ++++ +++ Example 17 +++ +++ +++ ++ +++ Example 18 +++ +++ +++ +++ +++ Example 19 +++ +++ ++ +++ +++ Example 20 +++ ++ +++ ++ +++ Example 21 +++ +++ +++ +++ +++ Example 22 +++ ++ +++ +++ +++ Example 23 +++ +++ +++ +++ ++ Example 24 +++ ++ ++ ++++ +++ Example 25 +++ ++++ +++ +++ ++ Example 26 +++ +++ +++ +++ +++ Example 27 ++++ +++ +++ +++ +++ Example 28 +++ ++ ++++ +++ ++  * Judgment criteria-: 8 mm or less, +: 8 to 10 mm, ++: 10 to 12 mm, ++: 12 to 15 mm, ++++: 15 mm or more

Experimental Example 2: Anti-inflammatory Experiment

In order to examine the anti-inflammatory effects on the extract, the left ear of the mouse was used as the control site and the right ear as the test site. One hour after the last application, ethanol was applied to the left ear, and 2 mg / ear of arachidonic acid was applied to the right ear. After 1 hour, the degree of ear edema was repeated three times with a micrometer.

Anti-inflammatory effect was determined based on the arachidonic acid (Arachidonic acid) treated group as shown in Equation 1 below the edema inhibition rate is shown in Table 6 below.

A: Average thickness of control ears (thickness of arachidonic acid treated ears-thickness of untreated ears)

B: thickness of sample coated group ears (thickness of arachidonic acid treated ears-thickness of untreated ears)

Ear thickness and inflammation inhibition rate by topical application division density Ear thickness (㎛) % Inhibition (Μg / ml) Before sample processing After sample processing (Control) 0 263 562 - Indomethacin 2 mg / ear 252 423 42.8 Comparative Example 1 10 242 513 9.3 Comparative Example 2 10 256 533 7.5 Comparative Example 3 10 261 550 3.2 Comparative Example 4 10 253 535 5.8 Comparative Example 5 10 243 524 5.9 Comparative Example 6 10 229 509 6.5 Example 1 10 243 475 22.5 Example 2 10 265 491 24.3 Example 3 10 265 487 25.6 Example 4 10 272 485 28.9 Example 5 10 253 477 25 Example 6 10 219 449 23.2 Example 7 10 225 449 25.1 Example 8 10 265 486 26 Example 9 10 275 493 27.1 Example 10 10 262 482 26.3 Example 11 10 242 465 25.5 Example 12 10 211 432 26.2 Example 13 10 245 469 25.2 Example 14 10 236 455 26.9 Example 15 10 242 463 26 Example 16 10 243 467 25.1 Example 17 10 244 468 25 Example 18 10 263 495 22.5 Example 19 10 253 488 21.3 Example 20 10 254 489 21.5 Example 21 10 255 478 25.5 Example 22 10 253 473 26.3 Example 23 10 262 479 27.5 Example 24 10 242 465 25.3 Example 25 10 255 477 25.9 Example 26 10 253 483 23.2 Example 27 10 250 476 24.3 Example 28 10 258 478 26.5

Experimental Example 3: Stimulus Test (Closed Wrap Test)

5.0% aqueous solution of the mixed extract of the present invention and 0.1% aqueous solution of sodium lauryl sulfate were applied to a healthy adult male and female 20 people each time by patching a certain amount (0.2 g) of each sample on the back for 24 hours, and then removing the pin chamber. After 4 hours, the change in skin condition was visually read, and the stimulus was measured by the following Equation 2, and the results are shown in Table 7 below.

※ Criteria

-: No erythema or unusual phenomenon

+-: Slightly reddish

+: Significantly redder than the surroundings

++: more reddening and swelling than Zuiy

Skin irritation relief results sample Judgment result Stimulus ++ + +- - Control (sodium lauryl sulfate 0.1%) 2 4 7 7 1.05 Purified water 0 0 3 17 0.15 Comparative Example 1 2 6 6 6 1.20 Comparative Example 2 2 3 8 7 1.00 Comparative Example 3 One 6 5 8 1.00 Comparative Example 4 2 5 5 8 1.05 Comparative Example 5 2 4 6 8 1.00 Comparative Example 6 2 5 5 8 1.05 Example 1 0 0 3 17 0.15 Example 2 0 0 2 18 0.10 Example 3 One 0 2 17 0.25 Example 4 0 One 3 16 0.25 Example 5 0 3 3 14 0.45 Example 6 0 3 2 15 0.40 Example 7 0 0 4 16 0.20 Example 8 0 3 3 14 0.45 Example 9 0 2 4 14 0.40 Example 10 0 2 3 15 0.35 Example 11 0 One 5 14 0.35 Example 12 0 3 One 16 0.35 Example 13 0 0 2 18 0.10 Example 14 0 0 5 15 0.25 Example 15 One 2 5 12 0.60 Example 16 0 2 2 16 0.30 Example 17 0 0 5 15 0.25 Example 18 0 2 3 15 0.35 Example 19 One 0 3 16 0.30 Example 20 0 0 6 14 0.30 Example 21 0 0 5 15 0.25 Example 22 One One 2 16 0.35 Example 23 0 2 2 16 0.30 Example 24 0 One 3 16 0.25 Example 25 0 2 2 16 0.30 Example 26 0 One 5 14 0.35 Example 27 0 0 9 11 0.45 Example 28 0 0 6 14 0.30

Experimental Example 4: In vitro  DOPA oxidative activity inhibition test

In order to examine the whitening effect of the mixed extract of the present invention, 850 µl of 0.1M phosphate buffer (pH 7.0), 50 µl of sample solution (each solution), and mushroom tyrosinase (1500-2,000) U / ml 50 μl (or human tyrosinase) solution was added in this order and reacted at 37 ° C. for 6 minutes. 50 μl of a 0.06 mM L-DOPA (L-3,4-dihydroxyphenylalanine) solution was added to the solution, followed by reaction at 37 ° C. for 1 minute. After the experiment, the absorbance was measured at 475 nm using a microplate reader. 0.1 M phosphate buffer solution (pH 7.0) was added instead of the sample solution as the blank sample solution. The concentration of the sample at 50% activity inhibition (IC ₅₀ ) was calculated using the appropriate program. The results are shown in Table 8 below.

division (IC ₅₀ ) concentration (Μg / ml) Arbutin 120 Comparative Example 1 - Comparative Example 2 - Comparative Example 3 - Comparative Example 4 - Comparative Example 5 - Comparative Example 6 - Example 1 700 Example 2 850 Example 3 800 Example 4 420 Example 5 520 Example 6 1210 Example 7 820 Example 8 510 Example 9 650 Example 10 510 Example 11 530 Example 12 560 Example 13 650 Example 14 630 Example 15 530 Example 16 560 Example 17 530 Example 18 780 Example 19 650 Example 20 950 Example 21 560 Example 22 660 Example 23 860 Example 24 940 Example 25 620 Example 26 630 Example 27 680 Example 28 610

Prescription Example 1 and Comparative Prescription Example 1

Prescription example of nutrition lotion in the cosmetic composition containing the extract of Example 4 is shown in Table 9.

The raw materials 2, 12, 14, 15, and 18 were heated to 80 ° C. and 85 ° C. with mixed agitation, put into the manufacturing unit, and then the emulsifier was activated. The raw materials 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, and 16 were heated to 80 to 85 ° C., and then emulsified. After emulsification, the mixture is cooled to 50 ° C. while stirring using a stirrer, and then the raw material 17 is added and cooled to 45 ° C., then the raw material 1 is added and stirred uniformly, then cooled to 30 ° C. and aged.

number Raw material Prescription Example 1 Comparative Prescription 1 One Mixed Extract (Example 4) 10.0 - 2 glycerin 7.0 7.0 3 Cetyl octanoate 5.0 5.0 4 Ceramide 0.7 0.7 5 Squalane 5.0 5.0 6 Stearic acid 0.5 0.5 7 Petrolatium 2.0 2.0 8 Cetanol 0.5 0.5 9 Glyceryl Stearate SE 0.7 0.7 10 Polysorbate 80 0.5 0.5 11 Octyldodecyl Myristate 3.0 3.0 12 Sodium hyaluronate 3.0 3.0 13 Mineral oil 3.0 3.0 14 Carvermer 0.2 0.2 15 Triethanolamine 0.2 0.2 16 antiseptic a very small amount a very small amount 17 Spices a very small amount a very small amount 18 Purified water Remaining amount Remaining amount

Prescription Example 2 and Comparative Prescription Example 2

Prescription example of nutrition cream in the cosmetic containing the extract of Example 4 is shown in Table 10 below.

The raw materials 2, 3, 5, 14, 15, 16, 19 were mixed and stirred and heated to 80-85 ° C. and fed into the manufacturing unit, followed by the operation of an emulsifier, and the raw materials 4, 6, 7, 8, 9, 10, 11, 12, 13, and 17 were heated to 80 to 85 ° C., and then emulsified. After emulsification, the mixture is cooled to 50 ° C. while stirring using a stirrer, and then the raw material 18 is added and cooled to 45 ° C., then the raw material 1 is added and stirred uniformly, then cooled to 30 ° C. and aged.

number Raw material Prescription Example 2 Comparative Prescription 2 One Mixed Extract (Example 4) 10.0 - 2 glycerin 15.0 15.0 3 Butylene Glycol 5.0 5.0 4 Ceramide 0.7 0.7 5 Sodium hyaluronate 15.0 15.0 6 Cetiaryl Alcohol 3.0 3.0 7 Shea butter 3.0 3.0 8 Glyceryl Stearate SE 3.0 3.0 9 Sunflower oil 10.0 10.0 10 Glyceryl Stearate / PEG-100 Stearate 2.0 2.0 11 Solbitan Sesquioleate 0.4 0.4 12 Hydrogenated Polydecene 3.0 3.0 13 Hydrogenated Vegetable Oil 1.0 1.0 14 Disodium EDTA 0.02 0.02 15 Triethanolamine 0.05 0.05 16 Carvermer 0.1 0.1 17 antiseptic a very small amount a very small amount 18 Spices a very small amount a very small amount 19 Purified water Remaining amount Remaining amount

Prescription Example 3 and Comparative Prescription Example 3

Prescription example of the massage cream in the cosmetic composition containing the extract of Example 4 is shown in Table 11.

The raw materials 12, 13, 15, 16, 17, 19, and 21 were heated to 80 ° C to 85 ° C with mixed agitation, fed into the manufacturing unit, and then the emulsifier was activated. Raw materials 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, and 17 were heated to 80 to 85 ° C., and then emulsified. After emulsification, the mixture is cooled to 50 ° C. while stirring using a stirrer, and then the raw material 18 is added and cooled to 45 ° C., then the raw material 1 is added and stirred uniformly, then cooled to 30 ° C. and aged.

number Raw material Prescription Example 3 Comparative Prescription 3 One Mixed Extract (Example 4) 10.0 - 2 Beeswax 2.0 2.0 3 Polysorbate 60 1.5 1.5 4 Sorbitan sesquioleate 0.4 0.4 5 Liquid paraffin 40.0 40.0 6 Squalane 5.0 5.0 7 Petrolatium 2.0 2.0 8 Glyceryl Stearate / Sebum 100 Stearate 2.0 2.0 9 Cetiaryl Alcohol 1.3 1.3 10 Isopropyl myristate 3.0 3.0 11 Fiji 60 Hydrogenated Castor Oil 3.0 3.0 12 Propylene glycol 5.0 5.0 13 Disodium EDTA 0.03 0.03 14 Sorbitan stearate 0.3 0.3 15 Sodium hydroxide 0.04 0.04 16 Carvermer 0.13 0.13 17 Panthenol 0.2 0.2 18 antiseptic a very small amount a very small amount 19 Pigment a very small amount a very small amount 20 Spices a very small amount a very small amount 21 Purified water Remaining amount Remaining amount

Test Example 1 Experiment for Confirming Effect of Improved Skin Trouble

When applying the skin to the nutrition cream of Formulation Example 2 and Comparative Example 2, the following experiment was carried out to confirm the effect of improving the skin trouble healing.

Twenty patients aged 15 to 35 years who had skin problems such as acne, cosmetic allergy, irritation relief, and whitening effect for 2 years or longer were investigated. To the same person, the nutritional cream of Formulation Example 2 on the left cheek and the nutritional cream of Comparative Example 2 on the right cheek were washed every evening and then applied for 60 days, and then the degree of improvement of skin trouble was measured.

division Skin trouble improvement (persons) (%) Prescription Example 2 very good 5 25 good 8 40 is average 5 25 so so 2 10 Comparative Prescription Example 2 very good One 5 good 2 10 is average 8 40 so so 9 45

As shown in Table 12, it was found that the cosmetic composition of Formulation Example 2 prepared by adding the natural mixed extract is superior to the skin healing improvement effect than Comparative Formula 2.

As described above, the cosmetic according to the present invention is very effective in the treatment of skin problems such as acne, cosmetic allergy, irritation, whitening effect by using a mixture of astronomical dong, Kanto and kelp extract very excellent antibacterial and anti-inflammatory effect It is expected to be of great help, especially for people with chemical-sensitive skin, using natural ingredients.

Claims (6)

Astronomical dong, Kanto and kelp is 0.5 to 3: 0.5 to 3: 0.5 to 3, the skin trouble improvement cosmetics, characterized in that it contains an extract mixed as an active ingredient. The cosmetic according to claim 1, wherein the astronomical dong, Kanto and kelp contain an extract mixed in a weight ratio of 0.8-2: 0.8-2: 0.8-2. The cosmetic according to claim 1, wherein the extract is extracted with water, ethanol, butylene glycol, propylene glycol alone or two or more mixed solvents. The cosmetic according to claim 2, wherein the extract is obtained by immersing at 4 to 40 ° C for 1 to 15 days or extracting by heating at 40 to 100 ° C for 2 to 20 hours. The cosmetic according to claim 1, wherein the extract contains 0.001 to 30% by weight. The cosmetic according to claim 1, wherein the cosmetic is a formulation selected from lotion, lotion, cream and essence.