KR101146206B1 - Cosmetic Composition And Composition of Skin External Application - Google Patents

Abstract

The present invention is: bamboo leaf extract, centella extract, red ginseng extract, ginseng extract, golden extract, peony root extract, peppermint extract, macmundong extract, green leaf extract, safflower extract, yellow white extract, honey extract, casualty extract, magnolia bark extract, white paper Cosmetic composition for sensitive skin improvement or hypoallergenic / irritant alleviation containing extracts, turmeric extracts, Angelica extracts, sterling silver extracts, situational mushroom extracts, red ginseng extracts, changja extract, Genistein and resveratrol as active ingredients The external preparation composition is disclosed.
The cosmetic composition and the external preparation composition for skin according to the present invention include plant natural extracts having the effects of sedation of the skin, itching inhibition / improvement, antibacterial, anti-inflammatory, antioxidant, anti-atopic properties, etc. It is effective in preventing and allergic reactions due to hypoallergenicity to the skin and can alleviate or improve skin problems such as itching, inflammation, erythema, skin damage.

Description

Cosmetic composition and composition for external application

The present invention relates to a cosmetic composition for improving sensitive skin, and more particularly, by containing various types of vegetable extracts useful for skin improvement as an active ingredient to stabilize sensitive, irritant or reactive skin and to relieve itching, burning and inflammation. The present invention relates to a cosmetic composition and an external preparation for skin that effectively improve sensitive skin such as atopic skin and alleviate or prevent irritation to the skin.

It is well known that certain skin types are more sensitive than others, and these skins are commonly referred to as sensitive skins, which are more sensitive to contact stimulation or allergy than the average population. .

Although the cause of the sensitive skin is not clearly identified, it is generally known to be caused by external influences such as cosmetics, psychological / physical stress, air pollution, and other environmental substances.

Symptoms of the sensitive skin include a visible reaction such as erythema and skin dryness, itching, itching (pruritus) or inflammation, these sensitive skin holders are on the rise.

An example of the sensitive skin is a skin with atopic dermatitis, that is, atopy skin, wherein atopy is Greek, a-topos is strange, strange, unfamiliar, out of place, Abnormal reactions, bizarre and so on.

The atopic dermatitis is a skin inflammation that occurs when contact dermatitis irritates the skin or is exposed to a substance that causes an allergic reaction. Many types of natural or artificial chemicals around us promote contact dermatitis. This can be found in components such as soaps, cleaners, detergents, precious metals, perfumes, industrial solvents, cosmetics, textile finishes, shampoos or antibiotic ointments.

The symptoms of atopic dermatitis are accompanied by skin redness, skin edema, blisters, ulcers and severe itching. If the treatment for atopic dermatitis is not carried out, the skin is continuously exposed to a substance that promotes a skin reaction and the contact dermatitis becomes chronic, and the skin changes color and becomes severe due to chronic contact dermatitis. It can even cause hair loss.

0.5 to 1% of the population and 5 to 10% of children are suffering from atopic dermatitis. The time to develop atopic symptoms is usually 2 to 6 months, especially under 1 year of age. 85% appear within five years of age.

The atopic dermatitis is usually known as a disease when young, but 50% of the patients disappear within two stones, but 25% lasts to adolescence, and the remaining 25% may continue without disappearing even as adults.

Accordingly, in recent years, there has been an increasing demand for external skin composition such as human cleansers, hair shampoos, and hair conditioners, which can be used safely by sensitive or extremely sensitive skin holders such as atopic skin. Various researches on cosmetics and external skin products to improve the condition are actively conducted.

The cosmetic composition for atopic skin and (ultra) sensitive skin described above has an antiseptic effect that suppresses or alleviates the existing itch without causing itching and skin irritation, an inhibitory effect on inflammation, and a proliferation of a damaged skin barrier. There is a need for a bacterium inhibitory effect that inhibits bacteria and a moisturizing and skin barrier maintenance repair skin protection effect.

However, there have been academic studies and research showing that chemical preservatives (parabens, phenoxyethanol, diazolidinyl urea) used in general cosmetic formulations damage human DNA, and atopic dermatitis and sensitive skin cause sensitive itching. Alternatives are required.

In addition, mineral oil (Petrolatum) used in general cosmetic formulations forms a strong skin oil film and prevents skin breathing, causing erythema, itching, and inflammation in extremely sensitive atopic skin. Is required.

In addition, the antibiotics (Mycin), which are resistant to the inflammation of the atopic skin, and the propagation of bacteria, anti-inflammatory and antimicrobial substitutes for steroids, and a safe alternative with antimicrobial effects, and because of the characteristics of atopic cosmetics used since newborns PEG (polyethylene glycol), dibutylhydroxytoluene (DHT), butylhydroxyanisole (BHA), abobenzene, oxybenzone, isopropyl alcohol, synthetic surfactant, etc. There is a need for a manufacturing technique that does not use from to the composition preparation step.

In order to repair skin barrier damage, there is a need to develop a composition containing a component that promotes cell regeneration beyond protecting skin damaged by lipids (ceramides), oils, plant butters, and the like.

An object of the present invention is to provide a cosmetic composition and a topical skin composition suitable for sensitive skin, such as atopic skin.

In order to achieve the above object, the present invention is: bamboo leaf extract, centella asiatica extract, red ginseng extract, ginseng extract, golden extract, peony root extract, peppermint extract, macmundong extract, foliage extract, safflower extract, yellow white extract, honey extract, Sensitive skin improvement or hypoallergenic extract containing casualty extract, magnolia bark extract, white paper extract, turmeric extract, donkey extract, gold and silver coin extract, situation mushroom extract, red ginseng extract, changiza extract, genistein and resveratrol as active ingredients The present invention provides a cosmetic composition and an external preparation composition for skin.

And with respect to the total weight of the composition, the bamboo leaf extract, the centella extract, the red ginseng extract, the ginseng extract, the peppermint extract, the mackmundong extract, the green leaf extract, the safflower extract, the yellow white extract, the honey extract and the The filamentous extract, the magnolia bark extract, the white paper extract, the yogurt extract, the donkey extract, the gold sapphire extract, the situation mushroom extract, the ginseng extract and the changja extract each contain 0.5 to 1% by weight, The peony root extract is 1.5 to 2.5% by weight, respectively, the genistein and the resveratrol may each contain 0.1 to 0.5% by weight, but the range is not limited thereto.

The composition is characterized in that it is formulated with one or more formulation agents selected from the group consisting of argan oil and tea tree seed oil and shea butter.

Accordingly, the cosmetic composition may be formulated as a cream or lotion or skin. Here, the formulation agent is characterized in that it is mixed with the olive leaf extract in the composition.

On the other hand, with respect to the total weight of the composition, the argan oil and tea seed oil is contained 5 to 20% by weight, the shea butter is contained 0 to 10% by weight, the olive leaf extract is contained 0.5 to 4% by weight It is characterized by.

The cosmetic composition is a cosmetic composition for atopic skin, characterized in that the composition for improving, alleviating or suppressing atopic symptoms such as itching, inflammation.

The various extracts described above may be prepared according to a conventional extraction method known in the art, that is, using a conventional extraction solvent under the conditions of a typical temperature and pressure, the kind and content of the extraction solvent, etc. under any conditions Can be selected.

The extracts may be extracted using one or more extraction solvents selected from the group consisting of purified water, methanol, ethanol, glycerin, ethyl acetate, butylene glycol, propylene glycol, and the like, for example water and / or 70 % Ethanol or water and / or 1,3-butylene glycol may be used.

The extraction method includes hot water extraction method, thermal extraction method, reflux cooling extraction method, ultrasonic extraction method, supercritical extraction method using carbon dioxide, low temperature compression method, extraction method using ultrafiltration membrane having a constant molecular weight cut-off value, extraction method by various chromatography, etc. Conventional extraction methods known in the art can be used.

Herein, the golden extract and the peony root extract are exemplified by the ultrasonic extraction method, and have a high concentration of baikalline and baikallein content. Water and / or butylene glycol may be used as the extraction solvent of the ultrasonic extraction method, but is not limited thereto.

And the red ginseng extract and ginseng extract is exemplified to be manufactured through a supercritical extraction method, the supercritical extraction method is known as an extraction method that does not use chemicals, a technology for extracting high purity active ingredient at high pressure using carbon dioxide Known as

The other extracts except the red ginseng extract and the ginseng extract described above are extracted by ultrasonic extraction, but as described above, various extraction methods other than the ultrasonic extraction method and the supercritical extraction method may be used.

The cosmetic composition and the external preparation composition for skin according to the present invention include plant natural extracts having the effects of calming, itching inhibition / improvement of the skin, antibacterial, anti-inflammatory, antioxidant, anti-atopic properties, etc. It is effective in preventing and allergic reactions due to hypoallergenicity to the skin and can alleviate or improve skin problems such as itching, inflammation, erythema, skin damage.

The present invention is a cosmetic composition for sensitive skin and a composition for external application for skin containing 20 kinds of plant extracts as an active ingredient, hereinafter, specific examples of the present invention will be described in detail.

The composition according to the present invention is bamboo leaf extract, Centella asiatica extract, Red ginseng extract, Ginseng extract, Golden extract, Peony root extract, Peppermint extract, Macmundong extract, Green leaf extract, Safflower extract, Yellow white extract, Honey extract, Casualty extract, Magnolia bark extract , White paper extract, turmeric extract, Angelica extract, gold and silver extract, situation mushroom extract, red ginseng extract, Changja extract, Genistein and Resveratrol as an active ingredient.

Bamboo is a monocotyledonous plant, and is a generic term for perennial plants belonging to the family Paddyaceae (Poaceae) and Bamboo subfamily (Bambusoideae), and only the tall royal genus may be referred to as bamboo. Use an extract of bamboo leaves.

The bamboo is distributed worldwide, but mainly grows in the tropics and is especially common in the monsoon zones of Asia. In Korea, it is widely distributed in south central and Jeju islands. Its stems are round, round, and hollow, and in the case of tall royal genus, it grows up to 30m in height and 30cm in diameter.

The growth method of the bamboo grows naturally by stretching the stem in the ground to the side and roots and sprouts in the node. The leaves are narrow and long. Likes wet land and grows fast. It also rarely blooms, but when it blooms, I bloom all at once in a bamboo field.

The flower of bamboo is a kind of mutation that is not related to the propagation of bamboo. It is also known as a flowering disease or a natural highland. The flowering period varies from 3 years, 4 years, 30 years, 60 years, 120 years, and so on.

The centellae (Asiatic Pennywort) is a perennial herb of dicotyledonous plants, dianthus, hawthorn, and apiaceae, mainly distributed in Korea, Japan and China, and lives in humid areas, and is used for medicinal purposes in India.

Since the red ginseng and ginseng are well known, the description thereof is omitted, and the red ginseng extract and the ginseng extract constituting the present invention may be commercially available, for example, the product of the Korea Ginseng Corporation.

Skullcap is a perennial herb of the dicotyledon and moss plant. It grows in the grass of the mountain and grows as medicinal plants about 20 ~ 60cm in height. The golden leaves come out several times, grow in abandonment, and have hairs and branches, leaves are opposite, lanceolate, and the edges are flat. In oriental medicine, the gold is used as an antipyretic, diuretic, branch, yedam and anti-inflammatory agent.

Peony is also called a neck (단 丹), 2m high, the branch is thick and hairless. The leaves of the peony are three-ply, the small leaves are egg-shaped, divided into 2-5 pieces, the leaf surface is hairless, the back side has fine hairs, and is often white. The root of the peony has pharmacological activities such as anti-inflammatory, headache, back pain, stomachache, and hemostasis.

The golden extract and peony root extract is an antimicrobial agent to prevent bacterial propagation in the composition according to the present invention to improve the preservation, antimicrobial agent (natural preservatives) and exhibits antimicrobial activity.

The roots of the gold and peony include ingredients such as Baicalin, Baicalein, Wagonon, Wogoniside, Di-methyl Tetra-hydroxy Flavone, etc. These ingredients are known to exhibit antimicrobial, anti-inflammatory, antioxidant and anti-atopic effects.

Peppermint is a perennial root of nectar and the main ingredient of peppermint oil is menthol, which is medicated as a coating agent, analgesic agent, exciter, nutrient agent, insect repellent, or as a refreshing agent or fragrance for toothpaste, jam, candy, cosmetics and tobacco. .

Snake's beard is a perennial herb that grows in the shade. The tuber root of the pulse is used as an anti-inflammatory, tonic, anti-tussive, expectorant and cardiac agent, and is known to have pharmacological effects such as diuretic and bacteriostatic.

Foliage is the leaf of peach tree. Also, safflower is also called honglam (이), biscuit, otnamul, and its height is about 1m. The safflower is used for gynecologic disease, pain relief and abdominal pain in oriental medicine. Oil from safflower seeds contains a lot of linolic acid, which is good for the prevention and treatment of atherosclerosis caused by excess cholesterol.

Hwangbaek is the dried bark of the yellow wall which belongs to the Unhyang family. Also called Hwanggyeongpi, it is distributed in all regions except Jeju and Jeonnam, and is distributed in Japan, Manchuria, China, Amur, and Usuri. Grows in the valley of

The pharmacological effect of the yellow and white blood glucose lowering and pneumococcal, pneumococcal tuberculosis, staphylococcus aureus and the like while inhibiting the growth of tumor cells, and inhibits the growth and sterilization. In the case of taking the yellow and white palpation of the secretion of gastric juice by palpation of taste reflex, and also to increase the appetite.

In addition, the yellow and white does not have a systemic effect of general alkaloids, so even when administered in a large amount, no side effects can be used as a formal agent as well as a stomach agent.

In addition, the drug does not produce resistance to various bacteria, so it can be used as a cleansing disinfectant when epidemic eye disease is epidemic. In addition to the above, the white blood has been reported to reduce blood pressure, suppress the central nervous system, and anti-inflammatory, and is used in oriental medicine in Hwangyeon Haedoktang, Shihocheonggantang, and Hyeonggaeyeongyotang.

Honey is stored by converting the nectar and pollen collected from the flowers of various plants into their food, which contains two monosaccharides: glucose and fructose, carbohydrates, minerals, vegetable pigments, yeast and Pollen and the like.

More than 80% of the components of the honey is a monosaccharide such as glucose (Glucose) and fructose (Fructose), this component has a very good hygroscopicity to form a moisture film in the skin has a continuous and powerful moisturizing effect.

Casualties are two-year-old grasses of the Apiaceae, also called snake-dorat. The young shoots of casualties are eaten as herbs, and the fruits are used as astringents, anti-inflammatory agents, insecticides, etc. In oriental medicine, mature fruits are used for the treatment of low back pain, vulva, and cystic diseases.

Magnolia is a medicine called magnolia bud as god (辛夷). The name God is given because it tastes a bit spicy. Since ancient times, sneezing is known as the best medicine, seeds, roots, bark, leaves, etc. are all used as medicine.

The god has the effect of passing through the sarcasm and penetrates the blockage, to relieve headaches, sinusitis, nasal congestion, toothache, eliminate the heat and winds of the five intestines, clear the head, blemishes on the face, freckles To cure.

If you make your skin creamy and apply it to your face, it will remove blemishes, freckles, and acne, and your face will be smooth. In addition, the god brightens the eyes, heals the chills of the body by the cold, and removes the symptoms of fever and itching due to the boil.

And the magnolia bark is known for its taste and cold nature. It cures various diseases caused by alcohol and has good effects on genital eczema, swelling, boils and various skin diseases. Magnolia bark improves vision and hearing, eliminates bad odors and makes urine come out well, and is very effective for back pain, headache, sore throat, rhinitis, sinusitis, etc.

White paper is a medicinal herb made from dried roots of the Angelica dahurica Bentham et Hooker or its variants. The white paper is a pain medicine for headache, nasal congestion and runny nose caused by a pandemic cold, and it is effective for gastrointestinal disorders, prenatal postpartum headache, dizziness, toothache, facial neuralgia, paralysis, and blood after menstrual bleeding, stool, feces. When mixed, it is effective for headaches, spears, swollen poisons and skin ulcers caused by sinusitis.

Pharmacological action of the white paper, antibacterial action, animal soft vascular movement center, respiratory center, excitatory action of the vagus nerve and spinal cord, coronary blood flow increase action, Baekjeon wind (白 殿 風: a condition in which white spots on flesh), septic disease (銀)屑 病: Chronic skin disease, an effect of multiple layers of white scales on the skin surface due to erythema and papules.

It is a perennial herb of Hyunsamaceae, cultivated as a medicinal plant, and its roots are thick, fleshy, extending laterally, reddish brown, and the stems stand straight and have a height of 20 ~ 30cm, and have hairs. In oriental medicine, the raw of the sulfur in the root of the jizohwang, dried dried gunjihwang, steamed and dried is called sujijihwang.

Sukjihwang is used as a blood donor, menstrual impurity, weak constitution, children's developmental dementia, dementia, premature ejaculation, erectile dysfunction, raw turmeric is used for fragile constitution, bleeding, nosebleed, uterine bleeding, physiological impurity, constipation It is effective for thirst caused by thirst and internal heat, and stops blood and nosebleeds.

Angelica and situation mushrooms are well known and additional explanations are omitted. Gold and silver coin refers to the flower buds of the honeysuckle or its varieties. The gold and silver coins are used when the heat is lowered and the chest is stuffy and thirsty.It is good for inflammation, and it causes boils, skin toxins, organ inflammation, and pus. do.

In addition, the gold and silver coin is used for dysentery, skin tissue necrosis due to heat poisoning, mastitis, etc., and is applied to colitis, gastric ulcer, cystitis, pharyngitis, tonsillitis, bronchitis, conjunctivitis and swelling, mumps, high fever, purulent infection.

As a pharmacological action of the gold and silver, antibacterial action, anti-inflammatory action, antipyretic action, leukocyte phagocytosis increase, central nervous system excitability, serum cholesterol lowering, ulcer prevention effect and the like have been reported.

Ginseng is similar in efficacy to ginseng, has a peculiar smell, is persistent, and has a very weak bitterness. The ginseng is used for dysentery, lobster, genital pruritus, skin itch, etc. due to weed and fever, and when there is a pain in the urine due to bladder fever.

The pharmacological effects of ginseng have been reported to treat leukopenia, anti-radioactivity, increased coronary blood flow, strengthening heart muscle, lowering blood glucose, anti-tumor, antibacterial, immune function.

Chang-ja is the fruit of the apophysis of the Asteraceae. It is a medicine that removes the abundance. It is used for sinusitis, rhinitis, headache, fever, cough, quadriplegia, and discomfort when itching, skin itching and otitis media. The pharmacological action of the Chang-za is reported to be toxic reactions to essential oils and alkaloids, hypoglycemia, leukocyte reduction prevention, cough, cardiac inhibition.

Genistein is one of isoflavone compounds isolated from soybeans, and is included in legumes such as soybeans and Egyptian beans, soybean processed products such as tofu and tempeh, and foods with plant protein tissues.

Genistein has been reported to inhibit weak estrogenicity, antioxidant function, anticancer action, atherosclerosis, osteoporosis, and acts as an antioxidant. Genistein also acts as a substance that controls uncontrolled cell growth associated with cancer cell growth in the body and regulates cell growth (growth factor) and cell division.

The resveratrol (Resveratrol) is a kind of polyphenols found in many plants, including berry, such as audi, peanuts, grapes, raspberries, cranberries, etc., and acts to lower serum cholesterol by antibacterial, anti-cancer and strong antioxidant action.

Genistein and resveratrol have a strong antioxidant effect, anti-inflammatory effect, anti-cancer effect and promote the replication of normal cells to promote cell regeneration, and has the effect of increasing the lifespan of normal cells appears in various papers and research results, purity It is recommended to use 90% Genistein 90 and 99% Resveratrol 99.

Genistein is a polyphenol that is relatively heat resistant and not easily lost, and resveratrol corresponds to sensitive polyphenols that are easily lost upon contact with heat and air or water.

The above 20 kinds of natural extracts may be mixed in various weight ratios to form a composition according to the present invention.

The weight ratio of the bamboo leaf extract, the golden extract, the peony root extract, the genistein and the resveratrol may be 0.5 to 1: 1.5 to 2.5: 1.5 to 2.5: 0.1 to 0.5: 0.1 to 0.5, but is not limited thereto. .

The Centella asiatica extract, Red ginseng extract, Ginseng extract, Peppermint extract, Macmundong extract, Green leaf extract, Safflower extract, Yellow white extract, Honey extract, Casualty extract, Magnolia bark extract, White paper extract, Sulfur extract, Angelica extract, Gold silver extract, and situation mushroom The extract, the ginseng extract and the Chang-za extract were also made to achieve a weight ratio of 0.5-1: 1.5-2.5 with the golden extract, respectively.

More specifically, the total weight of the composition, the bamboo leaf extract, the centella extract, the red ginseng extract, the ginseng extract, the peppermint extract, the mackmundong extract, the green leaf extract, the safflower extract, the yellow white extract and the honey The extract, the casualty extract, the magnolia bark extract, the white paper extract, the turmeric extract, the donkey extract, the gold gilding extract, the situation mushroom extract, the red ginseng extract and the changja extract each contain 0.5 to 1% by weight, The golden extract and the peony root extract each contain 1.5 to 2.5% by weight, the genistein and the resveratrol may each contain 0.1 to 0.5% by weight, but the range is not limited thereto.

The above-mentioned extracts have an antioxidant effect, and the composition may be formulated by one or more formulation agents selected from the group consisting of argan oil, tea tree seed oil and shea butter.

The argan oil and the tea seed oil and shea butter may be formulated into various formulations, such as liquid solutions, creams, lotions, depending on their contents as vegetable oils and fats.

Since the argan oil and the tea seed oil and the shea butter can be applied to the composition according to the present invention using a known commercial product, a description of a specific manufacturing method is omitted, and among these, the argan oil is an European organic certification body Ecocert (Ecocert). It is known to be manufactured by cold pressing method, and it is effective for anti-aging / wrinkle, atopic skin, skin elasticity, skin inflammation, and applied to various basic cosmetics, makeup, and hair products. It is known.

And the seed oil seed oil is exemplified that the sesame oil is produced in the same process by the known low-temperature compression method to prevent the destruction of the active ingredient, the shea butter is the fruit of the shea tree (shea tree) It is known that it is used as a skin moisturizer or emollient, and is used for food. It is also known to have antioxidant and anti-inflammatory effects in addition to skin moisturizing and regenerating effects.

In addition, the shea butter also has a sunscreen effect, the sunscreen effect is approximately SPF (sun protection factor) 6, hair conditioner because it stimulates the capillaries to moisturize the hair and scalp, increase nutrition and regeneration Also used as.

When the weight ratio of the argan oil and the tea seed oil combined is 10 wt% or more based on the total weight of the composition, the formulation of the composition may be a cream, and 5-10 wt% may be formulated into a lotion, and 5 wt% Less than% can be formulated into a liquid solution (skin).

The argan oil is contained in 0 to 20% by weight, more specifically 5 to 20% by weight of the total weight of the composition, the oil seed oil is contained 0 to 10% by weight, more specifically 5 to 10% by weight To prepare the composition according to the specific embodiment of the present invention, the shea butter is contained 0 to 10% by weight.

On the other hand, the composition according to the present invention may further contain an olive tree extract, it is applied as an emulsifier to mix the extracts. The olive tree extract is extracted from the olive leaf and fruit by ultrasonic extraction, for example, 20 parts by weight of the olive leaf and fruit in 50 parts by weight of water and 30 parts by weight of 1,3-butylene glycol in a mixed solvent 40 to Extracted by ultrasonic extraction at a temperature of 50 degrees for more than 2 hours and filtered with filter paper.

Composition according to a specific embodiment of the present invention, bamboo leaf extract 0.5-1% by weight, centella extract 0.5-1% by weight, red ginseng extract 0.5-1% by weight, ginseng extract 0.5-1% by weight, golden extract 2% by weight, Peony root extract 2%, peppermint extract 0.5 ~ 1% by weight, Megmundong extract 0.5 ~ 1% by weight, leaf extract 0.5 ~ 1% by weight, safflower extract 0.5 ~ 1% by weight, yellow white extract 0.5 ~ 1% by weight, honey extract 0.5 ~ 1% by weight, 0.5-1% by weight of filamentous extract, 0.5-1% by weight of magnolia bark extract, 0.5-1% by weight of white paper extract, 0.5-1% by weight of turmeric extract, 0.5-1% by weight of Angelica extract, 0.5 ~ 1% of gold-silver extract 1% by weight, Sichuan mushroom extract 0.5-1%, red ginseng extract 0.5-1%, Changiza extract 0.5-1%, argan oil 5-20%, tea seed oil 5-10%, shea butter 0 ~ 10% by weight, olive tree extract 0.5 ~ 4% by weight, Genistein 0.1 ~ 0.5% by weight, resveratrol 0.1 ~ 0.5% by weight and the remaining amount is purified water Atopic skin is extreme sensitive skin and vegetable cosmetic composition or external skin preparation.

However, the content of each component constituting the composition of the present invention is not limited to the above-described, it is possible to prepare a composition effective to improve the sensitive skin even if the content of the components are changed differently.

Hereinafter, the present invention will be described in more detail with reference to Examples. However, the following examples are illustrative of the present invention, and the content of the present invention is not limited to the following examples.

Manufacturing example  1: Method of preparing natural extracts

The bamboo leaf extract, Centella asiatica extract, Golden extract, Peony root extract, Peppermint extract, Macmundong extract, Maple leaf extract, Safflower extract, Yellow and white extract, Honey extract, Casualty extract, Magnolia bark extract, White paper extract, Turmeric extract, Angelica extract, Gold silver coin The extract, the mushroom extract, the ginseng extract, the Chang-za extract, can be prepared by a variety of known extraction methods, this embodiment describes an example produced by the ultrasonic extraction method. And the red ginseng extract and ginseng extract is described an example prepared by the supercritical extraction method.

In general, the ultrasonic wave has a higher frequency than the human audible frequency range, and the ultrasonic extraction method can complete the extraction in a very short time compared to the general solvent extraction, and the extraction time is reduced by approximately 10 times or more than the supercritical extraction. (Chung KW, WI Kim, IK Hong and KA Park. "Ultrasonic energy effects on squalene extraction from amaranth seed" .Applied Chemistry. 4 (2). 149-152 (2000). Kim WI, KW Chung, SB Lee, IK Hong and KA Park, "Ultrasonic energy effects on solvent extraction from amaranth seed oil". J. Korean Ind. Eng. Chem. 12 (3), 307-311 (2001))

More specifically, using the ultrasonic wave of 35 ~ 45kHz wavelength, in particular 40kHz wavelength ultrasonic wave, the output is extracted with the ultrasonic wave of the condition of about 300 to 500Watt.

2 parts by weight of the golden raw material and the extraction solvent (68 parts by weight of purified water and 30 parts by weight of 1,3-butylene glycol) are put in a well-known ultrasonic extractor and extracted by using ultrasonic waves at a temperature of 40 to 50 degrees for about 2 hours. The procedure is carried out to obtain a primary extract.

The butylene glycol has a moisturizing effect of maintaining the moisture of the skin because it has the effect of pulling moisture as a large organic alcohol particles, and corresponds to a safe solvent without skin irritation.

More specifically, after the ultrasonic wave was applied for 1 hour at an output of 300 Watts at approximately 40 degrees, the primary golden extract obtained by applying ultrasonic waves at an output of 500 Watts at a temperature of 50 degrees for 1 hour was cooled to room temperature to remove the golden raw material. do. And the primary extract was filtered with a filter paper of 0.4 ~ 0.8 ㎛ to obtain the liquid golden extract.

Since the manufacturing process of the peony root extract may proceed in the same manner as the manufacturing process of the golden extract, a description thereof will be omitted.

Next, the red ginseng extract and ginseng extract is exemplified by the supercritical extraction method using a known supercritical extractor.

More specifically, 5 g of the red ginseng is ground as it is or finely chopped into a 100 ml supercritical extraction tank to seal the extraction tank. Then, the red ginseng extract is extracted for about 2 hours using supercritical carbon dioxide at 300 bar, and the pressure is reduced to make the carbon dioxide into a gas state to separate the red ginseng extract and carbon dioxide.

At this time, the butylene glycol may be used as a co-solvent, the temperature may be carried out at room temperature or 30 to 40 degrees, and the red ginseng extract is obtained through centrifugation and filtration after being separated from the carbon dioxide.

Since the supercritical extraction method is already known in the art, the red ginseng extract may be prepared in the same manner as the known method, and the ginseng extract is also prepared by the same method as the red ginseng extract.

The remaining extracts except the red ginseng extract and the ginseng extract may also be obtained by ultrasonic extraction using the same amount of raw materials in the same manner as the extraction method of the golden extract.

Meanwhile, the argan oil was used as an import product of Morco acid (importer: Yul & Company (www.fairetrade.net), product name: organic pure argan oil-morco acid), and the olive tree extract was imported from France (importer: (Note: ) Marinoel (www.marinoel.com), product name: olive emulsifier-made in France, the shea butter is imported from France (importer: marinoel, product name: premium shea butter-made in France) It was.

The tea seed oil is obtained by a low temperature compression method, and in more detail can be obtained by milking 100g of the tea seed seeds at room temperature ~ 40 degrees.

Manufacturing example  2: preparation of the composition according to the invention

First, the golden extract and the peony extract are mixed with each other constituent except the golden extract and the peony root extract, and the golden extract and the whole mixture (for example, a mixture of the bamboo extract and the golden extract and the peony extract) Peony extract should be contained 2% by weight each.

After the purified water was heated to 100 degrees Celsius, it was cooled to 50 degrees, and the golden extract and the peony root extract were mixed with the purified water so that the golden extract and the peony extract were each 2% by weight.

Next, all the components except the Zenithine and resveratrol and olive tree extracts are mixed and stirred / mixed with a stirrer and cooled to room temperature. And finally, the composition according to the present invention is prepared by adding the Genistein and resveratrol and stirring with a stirrer.

In the present invention, the golden extract, the peony root extract, and the remaining ingredients except Genistein and resveratrol were mixed in almost similar weight ratios, so that each component showed even efficacy. The golden extract and the peony root extract were 2% by weight based on the total weight. If it exceeds, the antiseptic and antioxidant power is better, but the manufacturing cost increases, and if it is less than 1% by weight, problems with the antiseptic and antioxidant power may occur.

On the other hand, it is generally preferred that no thickener, metal ion sequestrant or pH (PH) regulator added to the cosmetic composition be added.

The present invention as described above as a natural plant cosmetic composition based on plant extracts to have a hypoallergenic, anti-inflammatory, anti-sedative, antibacterial, moisturizing and skin barrier protection, cell renewal effect required for atopic skin and sensitive skin as described above [Table 1] Was prepared in the Examples.

(Unit: wt%) Ingredient Example 1 Example 2 Bamboo Leaf Extract 0.5 One Centella extract 0.5 One Red Ginseng Extract 0.5 One Ginseng extract 0.5 One Golden extract 2 2 Peony Root Extract 2 2 Peppermint Extract 0.5 One Macmundong Extract 0.5 One Green leaf extract 0.5 One Safflower Extract 0.5 One Yellow White Extract 0.5 One Honey extract 0.5 One Casualty extract 0.5 One Magnolia Bark Extract 0.5 One White paper extract 0.5 One Foxglove Extract 0.5 One Angelica Extract 0.5 One Gold Coin Extract 0.5 One Situation Mushroom Extract 0.5 One Ginseng extract 0.5 One Changiza Extract 0.5 One Argan oil 20 20 Rapeseed oil 10 10 Shea Butter 8 10 Olive tree extract 3 4 Genistein 0.5 0.5 Resveratrol 0.1 0.5 Purified water Balance Balance

Experimental Example  1: atopy skin improvement effect

The improvement effect and usability evaluation for atopy skin and extremely sensitive skin about the composition prepared by combining the component ratio of the said [Table 1] were performed. The evaluation method was used as the evaluation value divided by the number of the evaluation score divided by 10 after using atopic dermatitis, 20 adult men and women and the cosmetic composition of the present invention for two weeks, the results are shown in Table 2 below.

Evaluation item Example 1 Example 2 Skin No irritant 5 4.5 Itching Suppression 4 5 Erythema and inflammation inhibition 4 5 Moisturizing effect 5 5 Full atopy suppression 4.5 4.9  Evaluation criteria 5: Very good, 4: Good, 3: Moderate.

According to the contents of Table 2, the vegetable cosmetic composition for atopic skin and extremely sensitive skin of the present invention exhibits an effect of suppressing and alleviating atopic skin symptoms excellently without stimulating extremely sensitive and atopic skin.

Experimental Example  2: Evaluation of antimicrobial activity of the finished product

Antimicrobial activity was evaluated by direct smear and visual inspection. The test strain was S. aureus, E. coli, P. aeruginosa, and Candida albicans (C. albicans) and yeast fungus (A. fumigatus) were used.

The test method is to adjust the bacteria incubated in YM bath for 24 hours to the concentration of # 0.5 McFarland standard, and then spread the cultures on each plate medium, dried for 3 to 5 minutes, and then Place the plate soaked on the medium and completely adhered to the test after 28 days, 1 day, 3 days, 7 days, the results are shown in Table 3 below.

                                                            (Unit) Test strain 0 days 1 day 3 days 7 days Staphylococcus aureus 2.2 * 10 ⁷ 0 0 0 Escherichia coli 2.2 * 10 ⁷ 0 0 0 Pseudomonas aeruginosa 2.2 * 10 ⁷ 10 0 0 Candida albicans 2.2 * 10 ⁷ 10 0 0 Yeast mold 1.8 * 10 ⁷ 0 0 0

According to the contents of Table 3, it can be seen that the composition according to the present invention exhibits a strong antimicrobial effect against five test strains commonly used in the antimicrobial activity test of cosmetics. In particular, by maintaining the antimicrobial effect for more than one week, it appears that there is a very good effect on the alleviation of the symptoms of the skin infection caused by the skin scratch and inhibiting bacterial growth.

Experimental Example  3: High Performance Liquid Chromatography ( HPLC Ingredient inspection

Genistein, resveratrol, methylparaben, ethylparaben, propylparaben, butylparaben, and phenoxyethanol were tested by the high performance liquid chromatography (HPLC) test method for the composition according to the present invention. Is the same as

HPLC Test Test item: Resveratrol, Genistein, Methyl-, ethyl-, propyl-, butyl paraben, Phenoxyethanol
Test facility: Phytonia Lab Test result investigation subject Test ingredient Unit Result Remark


Example 1 Resveratrol % 0.1155 HPLC Genistein % 0.4988 HPLC Methyl paraben % 0.000 HPLC Propyl paraben % 0.000 HPLC Butyl paraben % 0.000 HPLC Ethyl paraben % 0.000 HPLC Phenoxyethanol % 0.000 HPLC

 According to the contents of Table 4, it can be seen that the content of polyphenol, which is a high functional substance added to the finished product according to the present invention, is stable and preserved. In particular, resveratrol, because it is very sensitive to heat and easily lost, it can be seen that the formulation of the present invention has an excellent effect in preserving a very sensitive polyphenol, and the antioxidant capacity of the plant extract included together is very strong.

Accordingly, the composition according to the present invention can be variously applied to cosmetics, external preparations for skin, detergents for sensitive skin, drugs and the like.

Having looked at the preferred embodiment according to the present invention as described above, in addition to the embodiment described above, the fact that the present invention can be embodied in other specific forms without departing from the spirit or scope of the present invention It is obvious to them.

Therefore, the above-described embodiments should be regarded as illustrative rather than restrictive, and thus, the present invention is not limited to the above description and may be modified within the scope of the appended claims and their equivalents.

Claims (6)

Bamboo Leaf Extract, Centella Extract, Red Ginseng Extract, Ginseng Extract, Golden Extract, Peony Root Extract, Peppermint Extract, Macmundong Extract, Green Leaves Extract, Safflower Extract, Yellow White Extract, Honey Extract, Casualty Extract, Magnolia Bark Extract, White Paper Extract, Foxglove Extract Sensitive skin improvement or hypoallergenic cosmetic composition comprising, Angelica extract, sterling silver extract, mushroom extract, red ginseng extract, Changzai extract, Genistein and Resveratrol as an active ingredient. The method of claim 1,
The bamboo leaf extract, the Centella asiatica extract, the red ginseng extract, the ginseng extract, the peppermint extract, the Macmundong extract, the green leaf extract, the safflower extract, the yellow white extract, the honey extract and the casualty The extract, the magnolia bark extract, the white paper extract, the sulfuric acid extract, the donkey extract, the gilding extract, the situation mushroom extract, the ginseng extract and the changja extract each contain 0.5 to 1% by weight, the gold extract and the Moran root extract is contained 1.5 to 2.5% by weight, respectively, the genistein and the resveratrol composition, characterized in that it contains 0.1 to 0.5% by weight. The method according to claim 1 or 2,
The composition is characterized in that it is formulated by at least one formulation agent selected from the group consisting of argan oil and tea tree seed oil and shea butter. The method of claim 3,
Wherein said formulation is mixed with said olive leaf extract in said composition. The method of claim 4, wherein
The total weight of the composition, the argan oil and tea seed oil is contained 5 to 20% by weight, the shea butter is contained 0 to 10% by weight, the olive leaf extract is characterized in that it contains 0.5 to 4% by weight Composition. Bamboo Leaf Extract, Centella Extract, Red Ginseng Extract, Ginseng Extract, Golden Extract, Peony Root Extract, Peppermint Extract, Macmundong Extract, Green Leaves Extract, Safflower Extract, Yellow White Extract, Honey Extract, Casualty Extract, Magnolia Bark Extract, White Paper Extract, Foxglove Extract , Skin extract composition for sensitive skin, containing Angelica extract, sterling silver extract, situation mushroom extract, red ginseng extract, Chang-za extract, Genistein and Resveratrol as an active ingredient.