KR100248537B1 - 유기물질에 대한 안정화제로서 유용한 테트라메틸피페리딘 화합물 - Google Patents
유기물질에 대한 안정화제로서 유용한 테트라메틸피페리딘 화합물 Download PDFInfo
- Publication number
- KR100248537B1 KR100248537B1 KR1019920024858A KR920024858A KR100248537B1 KR 100248537 B1 KR100248537 B1 KR 100248537B1 KR 1019920024858 A KR1019920024858 A KR 1019920024858A KR 920024858 A KR920024858 A KR 920024858A KR 100248537 B1 KR100248537 B1 KR 100248537B1
- Authority
- KR
- South Korea
- Prior art keywords
- alkyl
- alkylene
- formula
- group
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/34—Heterocyclic compounds having nitrogen in the ring
- C08K5/3442—Heterocyclic compounds having nitrogen in the ring having two nitrogen atoms in the ring
- C08K5/3445—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Photolithography (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI913374A IT1252227B (it) | 1991-12-17 | 1991-12-17 | Composti tetrametilpiperidinici atti all'impiego come stabilizzanti per materiali organici |
| ITMI91A003374 | 1991-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR100248537B1 true KR100248537B1 (ko) | 2000-04-01 |
Family
ID=11361349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920024858A Expired - Fee Related KR100248537B1 (ko) | 1991-12-17 | 1992-12-16 | 유기물질에 대한 안정화제로서 유용한 테트라메틸피페리딘 화합물 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5310767A (enExample) |
| EP (1) | EP0548015B1 (enExample) |
| JP (1) | JPH05255312A (enExample) |
| KR (1) | KR100248537B1 (enExample) |
| BR (1) | BR9205032A (enExample) |
| CA (1) | CA2085379A1 (enExample) |
| DE (1) | DE69207370T2 (enExample) |
| ES (1) | ES2082434T3 (enExample) |
| IT (1) | IT1252227B (enExample) |
| TW (1) | TW242156B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1263892B (it) * | 1993-02-11 | 1996-09-05 | Graziano Vignali | Composti piperidin-triazinici atti all'impiego come stabilizzanti per materiali organici |
| US5721250A (en) * | 1993-12-23 | 1998-02-24 | Merck & Co. Inc. | Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
| AU780006B2 (en) | 2000-03-06 | 2005-02-24 | Acadia Pharmaceuticals, Inc. | Azacyclic compounds for use in the treatment of serotonin related diseases |
| NZ571695A (en) | 2001-12-28 | 2010-02-26 | Acadia Pharm Inc | Spiroazacyclic compounds as monoamine receptor for modulating 5-HT2A receptor-mediated events |
| US7253186B2 (en) | 2002-06-24 | 2007-08-07 | Carl-Magnus Andersson | N-substituted piperidine derivatives as serotonin receptor agents |
| MXPA04012893A (es) | 2002-06-24 | 2005-03-31 | Acadia Pharm Inc | Derivados de piperidina n-substituidos como agentes receptores de serotonina. |
| US7538222B2 (en) | 2002-06-24 | 2009-05-26 | Acadia Pharmaceuticals, Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| PT1587789E (pt) | 2003-01-16 | 2008-12-16 | Acadia Pharm Inc | Agonistas inversos selectivos para receptores 2a/2c da serotonina como agentes terapêuticos para doenças neurodegenerativas |
| US20050261278A1 (en) | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US7820695B2 (en) | 2004-05-21 | 2010-10-26 | Acadia Pharmaceuticals, Inc. | Selective serotonin receptor inverse agonists as therapeutics for disease |
| CA2580136C (en) | 2004-09-27 | 2015-08-18 | Acadia Pharmaceuticals Inc. | Synthesis of n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms |
| US7790899B2 (en) | 2004-09-27 | 2010-09-07 | Acadia Pharmaceuticals, Inc. | Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms |
| CA2681506C (en) | 2007-03-19 | 2016-05-24 | Perry Peters | Combinations of 5-ht2a inverse agonists and antagonists with antipsychotics |
| TWI386451B (zh) * | 2009-05-12 | 2013-02-21 | Nanya Plastics Corp | 一種pvc樹脂組成物及其製品 |
| CA2992728A1 (en) | 2015-07-20 | 2017-01-26 | Acadia Pharmaceuticals Inc. | Methods for preparing n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form c |
| WO2017165635A1 (en) | 2016-03-25 | 2017-09-28 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome p450 modulators |
| US10953000B2 (en) | 2016-03-25 | 2021-03-23 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome P450 modulators |
| EP3558311A1 (en) | 2016-12-20 | 2019-10-30 | Acadia Pharmaceuticals Inc. | Pimavanserin alone or in combination for use in the treatment of alzheimer's disease psychosis |
| EP3615028A1 (en) | 2017-04-28 | 2020-03-04 | Acadia Pharmaceuticals Inc. | Pimavanserin for treating impulse control disorder |
| US20210077479A1 (en) | 2017-08-30 | 2021-03-18 | Acadia Pharmaceuticals Inc. | Formulations of pimavanserin |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3684765A (en) * | 1970-01-08 | 1972-08-15 | Sankyo Co | Stabilization of synthetic polymers |
| GB1393551A (en) * | 1972-04-21 | 1975-05-07 | Ciba Geigy Ag | Piperidine derivatives |
| JPS557861B2 (enExample) * | 1972-10-04 | 1980-02-28 | ||
| IT1060458B (it) * | 1975-12-18 | 1982-08-20 | Chimosa Chimica Organica Spa | Composti piperidil triazinici adatti per la stabilizzazione di polimeri sintetici e procedimento per la loro preparazione |
| IT1097753B (it) * | 1978-07-28 | 1985-08-31 | Chimosa Chimica Organica Spa | Compcsti piperidinici, processo per la loro preparazione e loro impiego come stabil izzanti per polimeri sintetici |
| IT7921841A0 (it) * | 1979-04-13 | 1979-04-13 | Chimosa Chimica Organica Spa | Nuovi composti piperidinici, processo per la loro preparazione e loro impiego come stabilizzanti per polimeri sintetici. |
| DE2944729A1 (de) * | 1979-11-06 | 1981-05-14 | Hoechst Ag, 6000 Frankfurt | Neue triazinstabilisatoren |
| DE3382687D1 (de) * | 1982-09-30 | 1993-07-01 | Ciba Geigy Ag | Mit bis-(polyalkylpiperidinyl-amino)-1,3,5-triazinen stabilisierte polyolefine. |
| JPS59122487A (ja) * | 1982-12-28 | 1984-07-14 | Sankyo Co Ltd | ピペリジル−トリアジン−トリアミン誘導体及び高分子材料用安定剤 |
| IT1193659B (it) * | 1983-02-04 | 1988-07-21 | Chimosa Chimica Organica Spa | Composti piperidinil-triazinici utili come stabilizzanti per polimeri sintetici |
| JPS6181441A (ja) * | 1984-09-28 | 1986-04-25 | Adeka Argus Chem Co Ltd | 高分子材料組成物 |
| JPS6218444A (ja) * | 1985-07-16 | 1987-01-27 | Adeka Argus Chem Co Ltd | 安定化された高分子材料組成物 |
| IT1227334B (it) * | 1988-08-04 | 1991-04-08 | Ciba Geigy Spa | Composti piperidin triazinici atti all'impiego come stabilizzanti per materiali organici. |
| IT1231329B (it) * | 1989-07-28 | 1991-11-28 | Ciba Geigy Spa | Composti piperazin piperidinici atti all'impiego come stabilizzanti per materiali organici |
| IT1237129B (it) * | 1989-11-10 | 1993-05-18 | Valerio Borzatta | Composti piperidin-triazinici atti all'impiego come stabilizzanti per materiali organici. |
| IT1243374B (it) * | 1990-07-27 | 1994-06-10 | Ciba Geigy Spa | Composti piperidin-triazinici contenenti gruppi tetraidrofuranici o tetraidropiranici atti all'impiego come stabilizzanti per materiali organici |
| IT1243433B (it) * | 1990-10-03 | 1994-06-10 | Ciba Geigy Spa | Composti piperidin-triazinici atti all'impiego come stabilizzanti per materiali organici |
| IT1243409B (it) * | 1990-12-17 | 1994-06-10 | Ciba Geigy Spa | Composti piperidinici contenenti gruppi silenici atti all'impiego come stabilizzanti per materiali organici |
-
1991
- 1991-12-17 IT ITMI913374A patent/IT1252227B/it active IP Right Grant
-
1992
- 1992-12-08 EP EP92810967A patent/EP0548015B1/en not_active Expired - Lifetime
- 1992-12-08 ES ES92810967T patent/ES2082434T3/es not_active Expired - Lifetime
- 1992-12-08 DE DE69207370T patent/DE69207370T2/de not_active Expired - Fee Related
- 1992-12-10 US US07/988,503 patent/US5310767A/en not_active Expired - Fee Related
- 1992-12-11 TW TW081109941A patent/TW242156B/zh active
- 1992-12-15 CA CA002085379A patent/CA2085379A1/en not_active Abandoned
- 1992-12-16 KR KR1019920024858A patent/KR100248537B1/ko not_active Expired - Fee Related
- 1992-12-16 BR BR9205032A patent/BR9205032A/pt not_active Application Discontinuation
- 1992-12-17 JP JP4355130A patent/JPH05255312A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69207370D1 (de) | 1996-02-15 |
| CA2085379A1 (en) | 1993-06-18 |
| TW242156B (enExample) | 1995-03-01 |
| US5310767A (en) | 1994-05-10 |
| IT1252227B (it) | 1995-06-05 |
| JPH05255312A (ja) | 1993-10-05 |
| EP0548015A1 (en) | 1993-06-23 |
| EP0548015B1 (en) | 1996-01-03 |
| ITMI913374A1 (it) | 1993-06-17 |
| ES2082434T3 (es) | 1996-03-16 |
| BR9205032A (pt) | 1993-06-22 |
| DE69207370T2 (de) | 1996-11-14 |
| ITMI913374A0 (it) | 1991-12-17 |
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