KR100231078B1 - 단백질 검출용 분석 시험 스트립 및 이를 사용하는 단백질 검출방법 - Google Patents

단백질 검출용 분석 시험 스트립 및 이를 사용하는 단백질 검출방법 Download PDF

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KR100231078B1
KR100231078B1 KR1019920009663A KR920009663A KR100231078B1 KR 100231078 B1 KR100231078 B1 KR 100231078B1 KR 1019920009663 A KR1019920009663 A KR 1019920009663A KR 920009663 A KR920009663 A KR 920009663A KR 100231078 B1 KR100231078 B1 KR 100231078B1
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South Korea
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protein
error indicator
protein error
compound
test strip
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KR1019920009663A
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English (en)
Korean (ko)
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KR930000953A (ko
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폴에프.코레이
안젤라에이.마이클즈
로날드지.서머
Original Assignee
프랭클린 이.브레켄리지
마일즈 인코포레이티드
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Publication of KR930000953A publication Critical patent/KR930000953A/ko
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Publication of KR100231078B1 publication Critical patent/KR100231078B1/ko

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/64Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D293/00Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms
    • C07D293/10Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D293/12Selenazoles; Hydrogenated selenazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521Single-layer analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6827Total protein determination, e.g. albumin in urine
    • G01N33/6839Total protein determination, e.g. albumin in urine involving dyes, e.g. Coomassie blue, bromcresol green
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81Tube, bottle, or dipstick

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
KR1019920009663A 1991-06-06 1992-06-04 단백질 검출용 분석 시험 스트립 및 이를 사용하는 단백질 검출방법 KR100231078B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71095391A 1991-06-06 1991-06-06
US07/710,953 1991-06-06
US7/710,953 1991-06-06

Publications (2)

Publication Number Publication Date
KR930000953A KR930000953A (ko) 1993-01-16
KR100231078B1 true KR100231078B1 (ko) 1999-11-15

Family

ID=24856188

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920009663A KR100231078B1 (ko) 1991-06-06 1992-06-04 단백질 검출용 분석 시험 스트립 및 이를 사용하는 단백질 검출방법

Country Status (12)

Country Link
US (1) US5279790A (US07563621-20090721-C00007.png)
EP (1) EP0517050B1 (US07563621-20090721-C00007.png)
JP (1) JP3224419B2 (US07563621-20090721-C00007.png)
KR (1) KR100231078B1 (US07563621-20090721-C00007.png)
AT (1) ATE143144T1 (US07563621-20090721-C00007.png)
AU (1) AU637017B2 (US07563621-20090721-C00007.png)
CA (1) CA2070040A1 (US07563621-20090721-C00007.png)
DE (1) DE69213826T2 (US07563621-20090721-C00007.png)
DK (1) DK0517050T3 (US07563621-20090721-C00007.png)
ES (1) ES2092595T3 (US07563621-20090721-C00007.png)
GR (1) GR3021150T3 (US07563621-20090721-C00007.png)
TW (1) TW227043B (US07563621-20090721-C00007.png)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5326707A (en) * 1991-11-29 1994-07-05 Miles Inc. Composition and device for urinary protein assay and method of using the same
US5424215A (en) * 1994-02-07 1995-06-13 Miles Inc. Assay for the determination of protein in a biological sample
US5593895A (en) * 1995-04-27 1997-01-14 Bayer Corporation Method for the detection of protein in urine
US5616502A (en) * 1995-05-19 1997-04-01 Molecular Probes, Inc. Non-specific protein staining using merocyanine dyes
US5716851A (en) * 1996-01-16 1998-02-10 Bayer Corporation Glass/cellulose as protein reagent
US5753455A (en) * 1996-09-03 1998-05-19 Bayer Corporation Method for the detection of lysozyme using a protein error indicator dye in conjunction with an alkane sulfonic acid
US5908787A (en) * 1997-09-23 1999-06-01 Bayer Corporation Total protein detection method
WO2003001213A2 (en) * 2001-06-25 2003-01-03 Bayer Healthcare Llc Total protein detection methods and devices at low ph
US7459127B2 (en) * 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
AU2003206034A1 (en) * 2002-03-05 2003-09-16 Bayer Healthcare Llc Absorbing organic reagent into diagnostic test devices by formation of amine salt complexes
US7094354B2 (en) * 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7125711B2 (en) * 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7435381B2 (en) * 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
DE10346863A1 (de) * 2003-10-09 2005-05-04 Roche Diagnostics Gmbh On-Board-Kontrolle für Analyseelemente
US7776529B2 (en) 2003-12-05 2010-08-17 Life Technologies Corporation Methine-substituted cyanine dye compounds
US7282349B2 (en) 2003-12-16 2007-10-16 Kimberly-Clark Worldwide, Inc. Solvatochromatic bacterial detection
US7399608B2 (en) 2003-12-16 2008-07-15 Kimberly-Clark Worldwide, Inc. Microbial detection and quantification
US7300770B2 (en) 2004-12-16 2007-11-27 Kimberly-Clark Worldwide, Inc. Detection of microbe contamination on elastomeric articles
US20060084175A1 (en) * 2004-10-19 2006-04-20 Wayne Comper Colorimetric strip containing coomassie blue for semi-quantitation of albumin
US7598390B2 (en) 2005-05-11 2009-10-06 Life Technologies Corporation Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use
US9125973B2 (en) 2007-07-20 2015-09-08 Baxter International Inc. Antimicrobial housing and cover for a medical device
USRE47452E1 (en) 2007-07-20 2019-06-25 Baxter International Inc. Antimicrobial housing and cover for a medical device
CN102964863B (zh) * 2010-04-10 2014-04-16 大连理工大学 吲哚类半菁染料的合成与应用
CN101805526A (zh) * 2010-04-10 2010-08-18 大连理工大学 吲哚类半菁染料的合成与应用
US9933359B2 (en) * 2014-06-23 2018-04-03 Xerox Corporation Vendor exclusivity security feature for paper-based diagnostic solution
CN106349146A (zh) * 2016-08-11 2017-01-25 潘忠宁 一种新型光致变色材料的合成方法
CN106957247B (zh) * 2017-03-16 2020-03-20 长春万成生物电子工程有限公司 一种微蛋白指示剂的纯化方法
CN111004166A (zh) * 2019-12-27 2020-04-14 苏州络森生物科技有限公司 一种spdib的制备方法
CN116715977A (zh) * 2023-06-12 2023-09-08 沈阳师范大学 一种半菁染料的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2510633C3 (de) * 1975-03-12 1978-07-13 Boehringer Mannheim Gmbh, 6800 Mannheim Diagnostisches Mittel zum Nachweis von Eiweiß in Körperflüssigkeiten und dafür geeignete Indikatorfarbstoffe
JPS5767860A (en) * 1980-10-15 1982-04-24 Fuji Photo Film Co Ltd Material for multilayer analysis
US5049358A (en) * 1988-09-30 1991-09-17 Miles Inc. Composition and test device for assaying for proteins
US5122602A (en) * 1989-02-13 1992-06-16 Miles Inc. Chromogenic merocyanine enzyme substrates
US5264589A (en) * 1991-06-06 1993-11-23 Miles Inc. Merocyanine protein error indicators

Also Published As

Publication number Publication date
DE69213826D1 (de) 1996-10-24
EP0517050A2 (en) 1992-12-09
KR930000953A (ko) 1993-01-16
AU637017B2 (en) 1993-05-13
ATE143144T1 (de) 1996-10-15
GR3021150T3 (en) 1996-12-31
CA2070040A1 (en) 1992-12-07
JP3224419B2 (ja) 2001-10-29
AU1721092A (en) 1992-12-17
JPH05232119A (ja) 1993-09-07
EP0517050B1 (en) 1996-09-18
US5279790A (en) 1994-01-18
DK0517050T3 (US07563621-20090721-C00007.png) 1997-03-03
ES2092595T3 (es) 1996-12-01
EP0517050A3 (en) 1993-03-03
DE69213826T2 (de) 1997-01-30
TW227043B (US07563621-20090721-C00007.png) 1994-07-21

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