KR100218853B1 - 인체 혈청 알부민의 제조방법 - Google Patents

인체 혈청 알부민의 제조방법 Download PDF

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Publication number
KR100218853B1
KR100218853B1 KR1019920004650A KR920004650A KR100218853B1 KR 100218853 B1 KR100218853 B1 KR 100218853B1 KR 1019920004650 A KR1019920004650 A KR 1019920004650A KR 920004650 A KR920004650 A KR 920004650A KR 100218853 B1 KR100218853 B1 KR 100218853B1
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KR
South Korea
Prior art keywords
serum albumin
human serum
medium
acid
culture
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Expired - Lifetime
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KR1019920004650A
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English (en)
Korean (ko)
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KR920018218A (ko
Inventor
가오루 고바야시
시노부 구와에
도모시 오오야
히로또시 후꾸쯔가
아끼노리 스미
와따루 오따니
다까오 오무라
가즈마사 요꼬야마
Original Assignee
가마쿠라 아키오
요시또미 세이야꾸 가부시키가이샤
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Application filed by 가마쿠라 아키오, 요시또미 세이야꾸 가부시키가이샤 filed Critical 가마쿠라 아키오
Publication of KR920018218A publication Critical patent/KR920018218A/ko
Application granted granted Critical
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
KR1019920004650A 1991-03-20 1992-03-20 인체 혈청 알부민의 제조방법 Expired - Lifetime KR100218853B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP91-81719 1991-03-20
JP3081719A JPH0671432B2 (ja) 1991-03-20 1991-03-20 ヒト血清アルブミンの製造方法

Publications (2)

Publication Number Publication Date
KR920018218A KR920018218A (ko) 1992-10-21
KR100218853B1 true KR100218853B1 (ko) 1999-10-01

Family

ID=13754223

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920004650A Expired - Lifetime KR100218853B1 (ko) 1991-03-20 1992-03-20 인체 혈청 알부민의 제조방법

Country Status (9)

Country Link
US (1) US5334512A (OSRAM)
EP (1) EP0504823B1 (OSRAM)
JP (1) JPH0671432B2 (OSRAM)
KR (1) KR100218853B1 (OSRAM)
CA (1) CA2063511C (OSRAM)
DE (1) DE69220113T2 (OSRAM)
DK (1) DK0504823T3 (OSRAM)
ES (1) ES2102420T3 (OSRAM)
TW (1) TW198683B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240032272A (ko) 2022-09-02 2024-03-12 조신아 아동원예지도사 교육방법

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
CA2136564C (en) * 1993-11-26 2008-04-08 Kaoru Kobayashi Process for producing human serum albumin
JPH07308199A (ja) 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
PL335975A1 (en) 1997-04-03 2000-06-05 Yoshitomi Pharmaceutical Method of obtaining a heterologous protein
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
US8263401B2 (en) * 2004-05-26 2012-09-11 University Of Medicine And Dentistry Of New Jersey Adenylyl cyclase antibodies, compositions and uses thereof
WO2006066595A2 (en) * 2004-12-22 2006-06-29 Novozymes A/S Recombinant production of serum albumin
NZ602479A (en) 2008-05-15 2013-05-31 R Tech Ueno Ltd Pharmaceutical composition for the treatment of dry eye and/or corneal and conjunctival lesion
CA3047523A1 (en) * 2016-12-21 2018-06-28 Prometic Biosciences Inc. Methods and compositions for preventing or minimizing epithelial-mesenchymal transition
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
US12151045B2 (en) 2020-12-28 2024-11-26 Davol Inc. Reactive dry powdered hemostatic materials comprising a protein and a multifunctionalized modified polyethylene glycol based crosslinking agent

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
EP0079739A3 (en) * 1981-11-12 1984-08-08 The Upjohn Company Albumin-based nucleotides, their replication and use, and plasmids for use therein
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
EP0206733A1 (en) * 1985-06-17 1986-12-30 Genex Corporation Cloned human serum albumin gene
DK13087A (da) * 1986-01-13 1987-07-14 Genex Corp Gensekvens til fremstilling af human serumalbumin i bacillus
GB8613388D0 (en) * 1986-06-03 1986-07-09 Delta Biotechnology Ltd Induction of galactose regulated gene expression in yeast
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
JPS6460370A (en) * 1987-05-27 1989-03-07 Sankyo Co High-temperature culture of yeast
US5024947A (en) * 1987-07-24 1991-06-18 Cetus Corporation Serum free media for the growth on insect cells and expression of products thereby
JP2791418B2 (ja) * 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
JPH01240191A (ja) * 1988-02-16 1989-09-25 Green Cross Corp:The 酵母で機能する新規シグナルペプチドおよびこれを用いた異種蛋白質の分泌発現
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
GB8820951D0 (en) * 1988-09-07 1988-10-05 Delta Biotechnology Ltd Fermentation method
CA2017176A1 (en) * 1989-05-22 1990-11-22 Yoshitomi Pharmaceutical Industries Ltd. Albumin gene-containing plasmid, transformant carrying same, production of such transformant and production of albumin
JP2855130B2 (ja) * 1989-07-19 1999-02-10 吉富製薬株式会社 異種蛋白発現用融合酵母菌、該菌の製造方法および異種蛋白の製造方法
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240032272A (ko) 2022-09-02 2024-03-12 조신아 아동원예지도사 교육방법

Also Published As

Publication number Publication date
DE69220113D1 (de) 1997-07-10
ES2102420T3 (es) 1997-08-01
EP0504823A3 (en) 1993-04-07
EP0504823A2 (en) 1992-09-23
DE69220113T2 (de) 1997-09-25
TW198683B (OSRAM) 1993-01-21
CA2063511A1 (en) 1992-09-21
CA2063511C (en) 2001-11-27
JPH04293495A (ja) 1992-10-19
US5334512A (en) 1994-08-02
EP0504823B1 (en) 1997-06-04
KR920018218A (ko) 1992-10-21
JPH0671432B2 (ja) 1994-09-14
DK0504823T3 (da) 1997-06-23

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