JPWO2023058772A1 - - Google Patents

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Publication number
JPWO2023058772A1
JPWO2023058772A1 JP2023552980A JP2023552980A JPWO2023058772A1 JP WO2023058772 A1 JPWO2023058772 A1 JP WO2023058772A1 JP 2023552980 A JP2023552980 A JP 2023552980A JP 2023552980 A JP2023552980 A JP 2023552980A JP WO2023058772 A1 JPWO2023058772 A1 JP WO2023058772A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023552980A
Other languages
Japanese (ja)
Other versions
JPWO2023058772A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2023058772A1 publication Critical patent/JPWO2023058772A1/ja
Publication of JPWO2023058772A5 publication Critical patent/JPWO2023058772A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1288Transferases for other substituted phosphate groups (2.7.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58Aldonic, ketoaldonic or saccharic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01336UDP-N-acetyl-D-mannosamine dehydrogenase (1.1.1.336)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/08Transferases for other substituted phosphate groups (2.7.8)
    • C12Y207/08033UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase (2.7.8.33)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y501/00Racemaces and epimerases (5.1)
    • C12Y501/03Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C12Y501/03014UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) (5.1.3.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2023552980A 2021-10-08 2022-10-07 Pending JPWO2023058772A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021166476 2021-10-08
PCT/JP2022/037736 WO2023058772A1 (ja) 2021-10-08 2022-10-07 N-アセチルノイラミン酸及び/又はn-アセチルノイラミン酸含有糖質の生産能を有する微生物及び該微生物を用いたn-アセチルノイラミン酸及び/又はn-アセチルノイラミン酸含有糖質の製造方法

Publications (2)

Publication Number Publication Date
JPWO2023058772A1 true JPWO2023058772A1 (https=) 2023-04-13
JPWO2023058772A5 JPWO2023058772A5 (https=) 2025-08-04

Family

ID=85804393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023552980A Pending JPWO2023058772A1 (https=) 2021-10-08 2022-10-07

Country Status (6)

Country Link
US (1) US20240409974A1 (https=)
EP (1) EP4414447A4 (https=)
JP (1) JPWO2023058772A1 (https=)
CN (1) CN118103494A (https=)
AU (1) AU2022360817A1 (https=)
WO (1) WO2023058772A1 (https=)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2545078B2 (ja) 1987-04-06 1996-10-16 協和醗酵工業株式会社 核酸関連物質の製造法
JP3131655B2 (ja) 1992-02-03 2001-02-05 マルキン忠勇株式会社 N−アセチルノイラミン酸の製造法
JP3944866B2 (ja) 1996-06-18 2007-07-18 マルキンバイオ株式会社 N−アセチルノイラミン酸シンターゼ、及びこれを用いるn−アセチルノイラミン酸の製造方法
CA2237849C (en) 1996-09-17 2009-06-16 Kyowa Hakko Kogyo Co., Ltd. Processes for producing sugar nucleotides and complex carbohydrates
JP3939096B2 (ja) 1999-02-09 2007-06-27 協和醗酵工業株式会社 N−アセチルグルコサミン2−エピメラーゼおよび該酵素をコードするdna
EP1447447B1 (en) 2001-09-26 2009-11-11 Kyowa Hakko Bio Co., Ltd. Process for producing sialic acid-containing complex sugar
US7329514B2 (en) 2002-02-28 2008-02-12 Kyowa Hakko Kogyo Co., Ltd. Process for producing n-acetylneuraminic acid
KR101035043B1 (ko) 2002-07-01 2011-05-19 아르키온 라이프 사이언씨즈 엘엘씨 글루코사민 및 n-아세틸글루코사민의 제조를 위한 물질및 공정
JP5079272B2 (ja) 2006-06-30 2012-11-21 協和発酵バイオ株式会社 シチジン‐5´‐一リン酸‐n‐アセチルノイラミン酸およびn‐アセチルノイラミン酸含有糖質の製造法
CN101809143A (zh) 2006-09-26 2010-08-18 锡拉丘兹大学 用于增加唾液酸产量的代谢工程大肠杆菌
US20110165626A1 (en) 2006-10-03 2011-07-07 Centre National De La Recherche Scientifique (Cnrs High yield production of sialic acid (neu5ac) by fermentation
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
EP2675899A4 (en) 2011-02-16 2014-09-10 Glycosyn LLC BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN MANIPULATED BACTERIA
WO2015037698A1 (ja) 2013-09-12 2015-03-19 協和発酵バイオ株式会社 N-アセチルノイラミン酸及びn-アセチルノイラミン酸含有糖質の製造法
CA3171157A1 (en) * 2020-02-14 2021-08-19 Inbiose N.V. Production of glycosylated product in host cells
JP7483246B2 (ja) 2020-04-09 2024-05-15 株式会社スズテック 用土補給装置および用土補給方法

Also Published As

Publication number Publication date
EP4414447A4 (en) 2025-12-03
CN118103494A (zh) 2024-05-28
AU2022360817A1 (en) 2024-05-02
EP4414447A1 (en) 2024-08-14
WO2023058772A1 (ja) 2023-04-13
US20240409974A1 (en) 2024-12-12

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