JPWO2022211508A5 - - Google Patents
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- Publication number
- JPWO2022211508A5 JPWO2022211508A5 JP2023555736A JP2023555736A JPWO2022211508A5 JP WO2022211508 A5 JPWO2022211508 A5 JP WO2022211508A5 JP 2023555736 A JP2023555736 A JP 2023555736A JP 2023555736 A JP2023555736 A JP 2023555736A JP WO2022211508 A5 JPWO2022211508 A5 JP WO2022211508A5
- Authority
- JP
- Japan
- Prior art keywords
- conjugate
- independently
- alkyl
- amino acid
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2021-0041447 | 2021-03-30 | ||
| KR20210041447 | 2021-03-30 | ||
| PCT/KR2022/004552 WO2022211508A1 (ko) | 2021-03-30 | 2022-03-30 | 인간 cldn18.2에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024515934A JP2024515934A (ja) | 2024-04-11 |
| JPWO2022211508A5 true JPWO2022211508A5 (https=) | 2026-02-25 |
| JP2024515934A5 JP2024515934A5 (https=) | 2026-02-25 |
Family
ID=83459705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023555736A Pending JP2024515934A (ja) | 2021-03-30 | 2022-03-30 | ヒトｃｌｄｎ１８．２に対する抗体を含む抗体－薬物コンジュゲートおよびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240131178A1 (https=) |
| EP (1) | EP4321180A1 (https=) |
| JP (1) | JP2024515934A (https=) |
| KR (1) | KR20220136267A (https=) |
| CN (1) | CN117279663A (https=) |
| AU (1) | AU2022250810A1 (https=) |
| BR (1) | BR112023020093A2 (https=) |
| CA (1) | CA3213985A1 (https=) |
| IL (1) | IL307301A (https=) |
| MX (1) | MX2023011507A (https=) |
| WO (1) | WO2022211508A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019011655A (es) | 2017-03-29 | 2019-12-19 | Legochem Biosciences Inc | Profarmaco de dimero de pirrolobenzodiazepina y compuesto conjugado ligando-conector de este. |
| US20250242043A1 (en) * | 2022-04-06 | 2025-07-31 | Ligachem Biosciences Inc. | Antibody-drug conjugate comprising antibody against human trop2 and use thereof |
| KR20240101987A (ko) | 2022-12-23 | 2024-07-03 | 주식회사 와이바이오로직스 | 클라우딘-18.2에 특이적으로 결합하는 단클론항체 및 이의 용도 |
| EP4642489A1 (en) * | 2022-12-26 | 2025-11-05 | Full-Life Technologies HK Limited | Conjugate and uses thereof |
| JP2026510495A (ja) * | 2023-03-10 | 2026-04-07 | リガケム バイオサイエンシズ， インク． | ヒトｌ１ｃａｍに対する抗体を含む抗体－薬物コンジュゲートおよびその使用 |
| AR132368A1 (es) | 2023-04-18 | 2025-06-18 | Astrazeneca Ab | Conjugados que comprenden enlazadores escindibles |
| WO2025032556A1 (en) * | 2023-08-10 | 2025-02-13 | Beigene Switzerland Gmbh | Bioactive conjugates, preparation method and use thereof |
| WO2025032555A1 (en) * | 2023-08-10 | 2025-02-13 | Beigene Switzerland Gmbh | Bioactive conjugates, preparation method and use thereof |
| WO2025078881A2 (en) * | 2023-10-13 | 2025-04-17 | Ligachem Biosciences Inc. | Anti-claudin 18.2 antibody drug conjugates comprising topoisomerase i inhibitor and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880935A (en) | 1986-07-11 | 1989-11-14 | Icrf (Patents) Limited | Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates |
| IL106992A (en) | 1988-02-11 | 1994-06-24 | Bristol Myers Squibb Co | Acylhydrazone derivatives of anthracycline and methods for their preparation |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| ATE234635T1 (de) | 1995-12-22 | 2003-04-15 | Bristol Myers Squibb Co | Verzweigte hydrazongruppen enthaltende kuppler |
| HUE045348T2 (hu) | 2011-05-08 | 2019-12-30 | Legochem Biosciences Inc | Fehérje-hatóanyag konjugátumok és eljárás elõállításukra |
| KR101628872B1 (ko) | 2014-05-28 | 2016-06-09 | 주식회사 레고켐 바이오사이언스 | 자가-희생 기를 포함하는 화합물 |
| HRP20240795T1 (hr) | 2015-11-25 | 2024-09-13 | Ligachem Biosciences Inc. | Konjugati koji se sastoje od samozapaljujućih skupina i postupci povezani s njima |
| KR102847350B1 (ko) | 2015-11-25 | 2025-08-19 | 주식회사 리가켐바이오사이언스 | 분지된 링커를 포함하는 항체-약물 접합체 및 이의 제조방법 |
| MX2019011655A (es) * | 2017-03-29 | 2019-12-19 | Legochem Biosciences Inc | Profarmaco de dimero de pirrolobenzodiazepina y compuesto conjugado ligando-conector de este. |
| CN111867630B (zh) * | 2018-06-17 | 2023-10-13 | 上海健信生物医药科技有限公司 | 靶向cldn18.2的抗体、双特异性抗体、adc和car及其应用 |
-
2022
- 2022-03-30 IL IL307301A patent/IL307301A/en unknown
- 2022-03-30 US US18/285,194 patent/US20240131178A1/en active Pending
- 2022-03-30 AU AU2022250810A patent/AU2022250810A1/en active Pending
- 2022-03-30 JP JP2023555736A patent/JP2024515934A/ja active Pending
- 2022-03-30 BR BR112023020093A patent/BR112023020093A2/pt unknown
- 2022-03-30 KR KR1020220039969A patent/KR20220136267A/ko active Pending
- 2022-03-30 EP EP22781627.9A patent/EP4321180A1/en active Pending
- 2022-03-30 CN CN202280026360.1A patent/CN117279663A/zh active Pending
- 2022-03-30 WO PCT/KR2022/004552 patent/WO2022211508A1/ko not_active Ceased
- 2022-03-30 CA CA3213985A patent/CA3213985A1/en active Pending
- 2022-03-30 MX MX2023011507A patent/MX2023011507A/es unknown
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