JPWO2022196797A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2022196797A5 JPWO2022196797A5 JP2023507198A JP2023507198A JPWO2022196797A5 JP WO2022196797 A5 JPWO2022196797 A5 JP WO2022196797A5 JP 2023507198 A JP2023507198 A JP 2023507198A JP 2023507198 A JP2023507198 A JP 2023507198A JP WO2022196797 A5 JPWO2022196797 A5 JP WO2022196797A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- peptide
- substituent
- amino acid
- arginine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 25
- 125000001424 substituent group Chemical group 0.000 claims 17
- 150000001413 amino acids Chemical class 0.000 claims 15
- 125000006239 protecting group Chemical group 0.000 claims 13
- 125000003118 aryl group Chemical group 0.000 claims 10
- 238000004519 manufacturing process Methods 0.000 claims 9
- 239000004475 Arginine Substances 0.000 claims 8
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 8
- 238000010511 deprotection reaction Methods 0.000 claims 8
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 6
- 210000004899 c-terminal region Anatomy 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 125000003277 amino group Chemical group 0.000 claims 5
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 4
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 claims 2
- 125000001624 naphthyl group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- -1 9-fluorenylmethoxycarbonyl group Chemical group 0.000 claims 1
- 125000003368 amide group Chemical group 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 239000003223 protective agent Substances 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 125000004434 sulfur atom Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021045625 | 2021-03-19 | ||
| PCT/JP2022/012551 WO2022196797A1 (ja) | 2021-03-19 | 2022-03-18 | アミノ酸又はペプチドの製造方法、保護基形成用試薬、及び、化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022196797A1 JPWO2022196797A1 (https=) | 2022-09-22 |
| JPWO2022196797A5 true JPWO2022196797A5 (https=) | 2024-02-26 |
Family
ID=83320476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023507198A Pending JPWO2022196797A1 (https=) | 2021-03-19 | 2022-03-18 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240002432A1 (https=) |
| EP (1) | EP4310094A4 (https=) |
| JP (1) | JPWO2022196797A1 (https=) |
| CN (1) | CN116997559A (https=) |
| TW (1) | TW202302620A (https=) |
| WO (1) | WO2022196797A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2025110921A (ja) * | 2024-01-17 | 2025-07-30 | 富士フイルム株式会社 | ペプチドの製造方法、化合物、及びペプチド合成試薬 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE136551T1 (de) | 1988-05-10 | 1996-04-15 | Alpha 1 Biomedicals Inc | Festphase-verfahren zur gewinnung von thymosin- alpha-1 |
| JPH04360899A (ja) | 1991-06-04 | 1992-12-14 | Tanabe Seiyaku Co Ltd | 生理活性ペンタペプチドの製造法 |
| AU5059800A (en) * | 1999-04-08 | 2000-11-14 | Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts | Nucleoside derivatives with photo-unstable protective groups |
| JP5609815B2 (ja) * | 2010-08-26 | 2014-10-22 | 信越化学工業株式会社 | ポジ型化学増幅レジスト材料及びパターン形成方法 |
| JP5454458B2 (ja) * | 2010-11-25 | 2014-03-26 | 信越化学工業株式会社 | ポジ型レジスト材料及びパターン形成方法 |
| GB201310921D0 (en) * | 2013-06-19 | 2013-07-31 | Chemical & Biopharmaceutical Lab Of Patras S A | Peptide-resin conjugate and use thereof |
| EP3266792B1 (en) * | 2015-03-04 | 2020-12-30 | Jitsubo Co., Ltd. | Peptide synthesis method |
| US10633415B2 (en) * | 2015-03-06 | 2020-04-28 | Stealth Biotherapeutics Corp | Processes for preparing pharmaceutically relevant peptides |
| CA3098707A1 (en) * | 2018-05-31 | 2019-12-05 | Gap Peptides Llc | Method for solution-phase peptide synthesis and protecting strategies thereof |
| CN113508103A (zh) | 2019-02-28 | 2021-10-15 | 富士胶片株式会社 | 肽化合物的制造方法、保护基形成用试药及稠合多环芳香族烃化合物 |
| JP7628073B2 (ja) * | 2019-02-28 | 2025-02-07 | 富士フイルム株式会社 | ペプチド化合物の製造方法、保護基形成用試薬、及び、芳香族複素環化合物 |
| WO2020189621A1 (ja) * | 2019-03-15 | 2020-09-24 | 日産化学株式会社 | ペプチド化合物の製造方法 |
| WO2020262258A1 (ja) * | 2019-06-28 | 2020-12-30 | 富士フイルム株式会社 | ペプチド化合物の製造方法、保護基形成用試薬、及び、縮合多環芳香族炭化水素化合物 |
| JP7301965B2 (ja) | 2019-06-28 | 2023-07-03 | 富士フイルム株式会社 | ペプチド化合物の製造方法、保護基形成用試薬、及び、縮合多環化合物 |
-
2022
- 2022-03-18 WO PCT/JP2022/012551 patent/WO2022196797A1/ja not_active Ceased
- 2022-03-18 JP JP2023507198A patent/JPWO2022196797A1/ja active Pending
- 2022-03-18 CN CN202280022201.4A patent/CN116997559A/zh active Pending
- 2022-03-18 EP EP22771542.2A patent/EP4310094A4/en active Pending
- 2022-03-18 TW TW111110043A patent/TW202302620A/zh unknown
-
2023
- 2023-09-18 US US18/468,937 patent/US20240002432A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2019198833A1 (ja) | ペプチド合成方法 | |
| JP2023065511A (ja) | ペプチド化合物の製造方法、保護基形成用試薬、及び、芳香族複素環化合物 | |
| TWI866995B (zh) | 肽化合物的製造方法、保護基形成用試藥及縮合多環芳香族烴化合物 | |
| TWI811246B (zh) | 胜肽化合物之製造方法 | |
| JP6703669B2 (ja) | リュープロレリンの製造方法 | |
| US20240182517A1 (en) | Silane-containing condensed cyclic dipeptide compound, production method therefor, and method for producing polypeptide compound using same | |
| Li et al. | BOMI—A novel peptide coupling reagent | |
| KR20230112694A (ko) | 화학적 합성을 위한 조성물 및 방법 | |
| MX2010009514A (es) | Metodo de preparacion de combretastatina. | |
| JP2002502378A (ja) | グアニジル化試薬 | |
| CN119331045A (zh) | 制备肽的方法 | |
| JPWO2022196797A5 (https=) | ||
| JPWO2023106356A5 (https=) | ||
| CA2772310A1 (en) | N-terminal dimerization methods with bis-amindino acid-and bis-thioimidate derivatives | |
| JPWO2020262259A5 (https=) | ||
| CN102875643B (zh) | 用于合成生长抑素的主要肽片段 | |
| US20240002432A1 (en) | Method for producing amino acid or peptide, protective group-forming reagent, and compound | |
| JPH04502908A (ja) | アミノ酸のトリアルキルシリルエステルおよびペプチド合成におけるその使用 | |
| US20240368217A1 (en) | Peptide compound production method and amidation agent | |
| EP3661933A2 (en) | Chemical process for manufacturing monobactam antibiotic and intermediates thereof | |
| JP7625769B1 (ja) | 新規シリルタグを用いたペプチド化合物の製造方法 | |
| US5942601A (en) | Peptide synthesis with sulfonyl protecting groups | |
| JP7500119B2 (ja) | シラン含有縮合環ジペプチド化合物の製造方法 | |
| JP2011173822A (ja) | 金属錯体アレイとその製造法及び材料 | |
| TWI880950B (zh) | 胜肽化合物之製造方法 |