JPWO2022015656A5 - - Google Patents
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- JPWO2022015656A5 JPWO2022015656A5 JP2023501559A JP2023501559A JPWO2022015656A5 JP WO2022015656 A5 JPWO2022015656 A5 JP WO2022015656A5 JP 2023501559 A JP2023501559 A JP 2023501559A JP 2023501559 A JP2023501559 A JP 2023501559A JP WO2022015656 A5 JPWO2022015656 A5 JP WO2022015656A5
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- Japan
- Prior art keywords
- group
- compound
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- antibody
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- Prior art date
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023214174A JP7776485B2 (ja) | 2020-07-13 | 2023-12-19 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063051172P | 2020-07-13 | 2020-07-13 | |
| US63/051,172 | 2020-07-13 | ||
| US202163154531P | 2021-02-26 | 2021-02-26 | |
| US63/154,531 | 2021-02-26 | ||
| PCT/US2021/041304 WO2022015656A1 (en) | 2020-07-13 | 2021-07-12 | Camptothecin analogs conjugated to a glutamine residue in a protein, and their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023214174A Division JP7776485B2 (ja) | 2020-07-13 | 2023-12-19 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023534437A JP2023534437A (ja) | 2023-08-09 |
| JPWO2022015656A5 true JPWO2022015656A5 (enExample) | 2024-07-19 |
Family
ID=77168491
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023501559A Pending JP2023534437A (ja) | 2020-07-13 | 2021-07-12 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
| JP2023214174A Active JP7776485B2 (ja) | 2020-07-13 | 2023-12-19 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023214174A Active JP7776485B2 (ja) | 2020-07-13 | 2023-12-19 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20220072141A1 (enExample) |
| EP (2) | EP4406608A3 (enExample) |
| JP (2) | JP2023534437A (enExample) |
| KR (2) | KR20240038138A (enExample) |
| CN (2) | CN118085100A (enExample) |
| AU (2) | AU2021308190A1 (enExample) |
| BR (1) | BR112023000489A2 (enExample) |
| CA (1) | CA3183184A1 (enExample) |
| CL (1) | CL2023000098A1 (enExample) |
| CO (1) | CO2023001402A2 (enExample) |
| IL (2) | IL299153A (enExample) |
| MA (1) | MA71650A (enExample) |
| MX (2) | MX2023000544A (enExample) |
| WO (1) | WO2022015656A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3166732A1 (en) * | 2020-01-22 | 2021-07-29 | Medimmune Limited | Compounds and conjugates thereof |
| EP4223318A4 (en) * | 2020-09-30 | 2024-12-18 | Duality Biologics (Suzhou) Co., Ltd. | Antitumor compound, and preparation method therefor and use thereof |
| CN118829449A (zh) * | 2022-01-12 | 2024-10-22 | 瑞泽恩制药公司 | 与蛋白中的谷氨酰胺残基缀合的喜树碱类似物及其用途 |
| US20250114472A1 (en) * | 2022-01-24 | 2025-04-10 | Beijing Chempion Biotechnology Co., Ltd. | Conjugate and use thereof |
| EP4489791A1 (en) * | 2022-03-09 | 2025-01-15 | Merck Patent GmbH | Anti-gd2 antibodies, immunoconjugates and therapeutic uses thereof |
| WO2023217064A1 (zh) * | 2022-05-09 | 2023-11-16 | 同宜医药(苏州)有限公司 | 一种喜树碱衍生物,基于其的抗体-药物偶联物和药物组合物,及其应用 |
| WO2024026474A1 (en) | 2022-07-29 | 2024-02-01 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle |
| IL319866A (en) * | 2022-09-30 | 2025-05-01 | Beigene Switzerland Gmbh | Ligand-drug conjugates of exatacan analogs and their medical use |
| AU2023379457A1 (en) | 2022-11-14 | 2025-05-15 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes |
| KR20250133813A (ko) | 2022-12-21 | 2025-09-08 | 리제너론 파마슈티칼스 인코포레이티드 | Adc 접합을 위한 토포이소머라아제 i 억제제의 전구약물 및 이의 사용 방법 |
| EP4661914A1 (en) | 2023-02-09 | 2025-12-17 | Regeneron Pharmaceuticals, Inc. | Antibody-drug conjugates via inverse electron demand diels-alder reactions |
| WO2025014533A1 (en) | 2023-07-10 | 2025-01-16 | Regeneron Pharmaceuticals, Inc. | Anti-human cacng1 antibody-drug conjugates and uses thereof |
| WO2025038752A1 (en) * | 2023-08-14 | 2025-02-20 | Cancer Targeted Technology Llc | Psma binding ligand-linker conjugates and methods for use thereof |
| EP4537854A1 (en) * | 2023-10-04 | 2025-04-16 | Formosa Laboratories, Inc. | Compound for conjugation, conjugate and pharmaceutical composition comprising the same |
| WO2025078841A2 (en) | 2023-10-11 | 2025-04-17 | Antikor Biopharma Limited | Antibodies, conjugates, and uses thereof |
| WO2025103474A1 (zh) * | 2023-11-17 | 2025-05-22 | 成都康弘生物科技有限公司 | 双毒素抗体药物偶联物及其用途 |
| WO2025199666A1 (en) * | 2024-03-25 | 2025-10-02 | Canwell Biotech Limited | Multivalent linkers for high loading antibody-drug conjugates, and compositions and methods thereof |
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-
2021
- 2021-07-12 IL IL299153A patent/IL299153A/en unknown
- 2021-07-12 IL IL309173A patent/IL309173A/en unknown
- 2021-07-12 MA MA71650A patent/MA71650A/fr unknown
- 2021-07-12 US US17/373,524 patent/US20220072141A1/en active Pending
- 2021-07-12 BR BR112023000489A patent/BR112023000489A2/pt unknown
- 2021-07-12 MX MX2023000544A patent/MX2023000544A/es unknown
- 2021-07-12 JP JP2023501559A patent/JP2023534437A/ja active Pending
- 2021-07-12 KR KR1020247008244A patent/KR20240038138A/ko active Pending
- 2021-07-12 CN CN202410175152.9A patent/CN118085100A/zh active Pending
- 2021-07-12 CA CA3183184A patent/CA3183184A1/en active Pending
- 2021-07-12 WO PCT/US2021/041304 patent/WO2022015656A1/en not_active Ceased
- 2021-07-12 EP EP24176032.1A patent/EP4406608A3/en active Pending
- 2021-07-12 CN CN202180062762.2A patent/CN116390771A/zh active Pending
- 2021-07-12 AU AU2021308190A patent/AU2021308190A1/en active Pending
- 2021-07-12 KR KR1020237004637A patent/KR20230038738A/ko active Pending
- 2021-07-12 EP EP21749495.4A patent/EP4178625A1/en active Pending
-
2023
- 2023-01-10 MX MX2024003180A patent/MX2024003180A/es unknown
- 2023-01-10 CL CL2023000098A patent/CL2023000098A1/es unknown
- 2023-02-09 CO CONC2023/0001402A patent/CO2023001402A2/es unknown
- 2023-11-21 US US18/516,454 patent/US20240252661A1/en active Pending
- 2023-12-19 JP JP2023214174A patent/JP7776485B2/ja active Active
-
2024
- 2024-02-09 AU AU2024200822A patent/AU2024200822A1/en active Pending
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