JPWO2021119226A5 - - Google Patents

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JPWO2021119226A5
JPWO2021119226A5 JP2022535508A JP2022535508A JPWO2021119226A5 JP WO2021119226 A5 JPWO2021119226 A5 JP WO2021119226A5 JP 2022535508 A JP2022535508 A JP 2022535508A JP 2022535508 A JP2022535508 A JP 2022535508A JP WO2021119226 A5 JPWO2021119226 A5 JP WO2021119226A5
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JP
Japan
Prior art keywords
dsrna agent
nucleotides
nucleotide
modification
pharmaceutical composition
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2022535508A
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English (en)
Japanese (ja)
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JP2023506181A (ja
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Priority claimed from PCT/US2020/064159 external-priority patent/WO2021119226A1/fr
Publication of JP2023506181A publication Critical patent/JP2023506181A/ja
Publication of JPWO2021119226A5 publication Critical patent/JPWO2021119226A5/ja
Pending legal-status Critical Current

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JP2022535508A 2019-12-13 2020-12-10 ヒト第９染色体オープンリーディングフレーム７２（Ｃ９ＯＲＦ７２）ｉＲＮＡ剤組成物およびその使用方法 Pending JP2023506181A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962947605P 2019-12-13 2019-12-13
US201962947768P 2019-12-13 2019-12-13
US62/947,768 2019-12-13
US62/947,605 2019-12-13
PCT/US2020/064159 WO2021119226A1 (fr) 2019-12-13 2020-12-10 Agents et compositions d'arni ciblant c9orf72 - cadre de lecture ouvert 72 sur le chromosome 9 - humain et procédés d'utilisation

Publications (2)

Publication Number Publication Date
JP2023506181A JP2023506181A (ja) 2023-02-15
JPWO2021119226A5 true JPWO2021119226A5 (fr) 2023-12-15

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ID=74004172

Family Applications (1)

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JP2022535508A Pending JP2023506181A (ja) 2019-12-13 2020-12-10 ヒト第９染色体オープンリーディングフレーム７２（Ｃ９ＯＲＦ７２）ｉＲＮＡ剤組成物およびその使用方法

Country Status (14)

Country Link
US (1) US20230114649A1 (fr)
EP (1) EP4073251A1 (fr)
JP (1) JP2023506181A (fr)
KR (1) KR20220115995A (fr)
CN (1) CN115151641A (fr)
AU (1) AU2020402885A1 (fr)
BR (1) BR112022011417A2 (fr)
CA (1) CA3164599A1 (fr)
CL (1) CL2022001503A1 (fr)
CO (1) CO2022009787A2 (fr)
IL (1) IL293824A (fr)
MX (1) MX2022006433A (fr)
TW (1) TW202140509A (fr)
WO (1) WO2021119226A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3946374A4 (fr) * 2019-03-29 2023-07-19 University of Massachusetts Modulation, à base d'oligonucléotides, de c9orf72
US20210340535A1 (en) * 2020-03-27 2021-11-04 University Of Massachusetts DUAL-ACTING siRNA BASED MODULATION OF C9orf72
AU2022283796A1 (en) 2021-06-04 2023-11-09 Alnylam Pharmaceuticals, Inc. HUMAN CHROMOSOME 9 OPEN READING FRAME 72 (C9ORF72) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
WO2024036343A2 (fr) * 2022-08-12 2024-02-15 University Of Miami Agents thérapeutiques à base d'acide nucléique synergique et méthodes d'utilisation pour traiter des troubles génétiques
WO2024107765A2 (fr) 2022-11-14 2024-05-23 Regeneron Pharmaceuticals, Inc. Compositions et procédés d'administration médiée par le récepteur 3 du facteur de croissance des fibroblastes à des astrocytes

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