JPWO2021071858A5 - - Google Patents
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- Publication number
- JPWO2021071858A5 JPWO2021071858A5 JP2022520901A JP2022520901A JPWO2021071858A5 JP WO2021071858 A5 JPWO2021071858 A5 JP WO2021071858A5 JP 2022520901 A JP2022520901 A JP 2022520901A JP 2022520901 A JP2022520901 A JP 2022520901A JP WO2021071858 A5 JPWO2021071858 A5 JP WO2021071858A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- heteroatoms
- independently
- phosphoramidite
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962911334P | 2019-10-06 | 2019-10-06 | |
| US62/911,334 | 2019-10-06 | ||
| US202062959917P | 2020-01-11 | 2020-01-11 | |
| US62/959,917 | 2020-01-11 | ||
| US202063022559P | 2020-05-10 | 2020-05-10 | |
| US63/022,559 | 2020-05-10 | ||
| US202063069696P | 2020-08-24 | 2020-08-24 | |
| US63/069,696 | 2020-08-24 | ||
| PCT/US2020/054436 WO2021071858A1 (en) | 2019-10-06 | 2020-10-06 | Oligonucleotide compositions and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022551124A JP2022551124A (ja) | 2022-12-07 |
| JPWO2021071858A5 true JPWO2021071858A5 (ko) | 2023-10-17 |
Family
ID=75437497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022520901A Pending JP2022551124A (ja) | 2019-10-06 | 2020-10-06 | オリゴヌクレオチド組成物及びその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230220384A1 (ko) |
| EP (1) | EP4022059A4 (ko) |
| JP (1) | JP2022551124A (ko) |
| KR (1) | KR20220076508A (ko) |
| CN (1) | CN114585737A (ko) |
| AU (1) | AU2020363391A1 (ko) |
| BR (1) | BR112022006205A2 (ko) |
| CA (1) | CA3154768A1 (ko) |
| IL (1) | IL291933A (ko) |
| MX (1) | MX2022004101A (ko) |
| WO (1) | WO2021071858A1 (ko) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2872485T3 (da) | 2012-07-13 | 2021-03-08 | Wave Life Sciences Ltd | Asymmetrisk hjælpegruppe |
| WO2014012081A2 (en) | 2012-07-13 | 2014-01-16 | Ontorii, Inc. | Chiral control |
| MA43072A (fr) | 2015-07-22 | 2018-05-30 | Wave Life Sciences Ltd | Compositions d'oligonucléotides et procédés associés |
| CN114685589A (zh) | 2016-03-13 | 2022-07-01 | 波涛生命科学有限公司 | 用于亚磷酰胺和寡核苷酸合成的组合物和方法 |
| EP3544987A4 (en) | 2016-11-23 | 2020-11-18 | Wave Life Sciences Ltd. | COMPOSITIONS AND SYNTHESIS OF PHOSPHORAMIDITES AND OLIGONUCLEOTIDES |
| US11603532B2 (en) | 2017-06-02 | 2023-03-14 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods of use thereof |
| CA3065523A1 (en) | 2017-06-02 | 2018-12-06 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods of use thereof |
| US11718638B2 (en) | 2017-06-21 | 2023-08-08 | Wave Life Sciences Ltd. | Compounds, compositions and methods for synthesis |
| SG11202000274RA (en) | 2017-08-08 | 2020-02-27 | Wave Life Sciences Ltd | Oligonucleotide compositions and methods thereof |
| CA3072110A1 (en) | 2017-09-18 | 2019-03-21 | Wave Life Sciences Ltd. | Technologies for oligonucleotide preparation |
| SG11202001783YA (en) | 2017-10-12 | 2020-03-30 | Wave Life Sciences Ltd | Oligonucleotide compositions and methods thereof |
| CN113748116A (zh) * | 2019-03-20 | 2021-12-03 | 波涛生命科学有限公司 | 可用于寡核苷酸制备的技术 |
| EP4363574A1 (en) * | 2021-06-29 | 2024-05-08 | Korro Bio, Inc. | Methods and compositions for adar-mediated editing |
| US20230194709A9 (en) * | 2021-06-29 | 2023-06-22 | Seagate Technology Llc | Range information detection using coherent pulse sets with selected waveform characteristics |
| WO2023152371A1 (en) | 2022-02-14 | 2023-08-17 | Proqr Therapeutics Ii B.V. | Guide oligonucleotides for nucleic acid editing in the treatment of hypercholesterolemia |
| WO2023220428A1 (en) * | 2022-05-12 | 2023-11-16 | Wave Life Sciences Ltd. | Compositions for editing ass1 transcripts and methods thereof |
| WO2023220440A1 (en) * | 2022-05-12 | 2023-11-16 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods thereof |
| WO2024013361A1 (en) | 2022-07-15 | 2024-01-18 | Proqr Therapeutics Ii B.V. | Oligonucleotides for adar-mediated rna editing and use thereof |
| WO2024013360A1 (en) | 2022-07-15 | 2024-01-18 | Proqr Therapeutics Ii B.V. | Chemically modified oligonucleotides for adar-mediated rna editing |
| WO2024017817A1 (en) * | 2022-07-18 | 2024-01-25 | F. Hoffmann-La Roche Ag | Editing oligonucleotide |
| GB202215614D0 (en) | 2022-10-21 | 2022-12-07 | Proqr Therapeutics Ii Bv | Heteroduplex rna editing oligonucleotide complexes |
| WO2024110565A1 (en) | 2022-11-24 | 2024-05-30 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of hereditary hfe-hemochromatosis |
| WO2024114908A1 (en) | 2022-11-30 | 2024-06-06 | Eberhard Karls Universität Tübingen | Chemically modified antisense oligonucleotides (asos) and compositions comprising the same for rna editing |
| GB202218090D0 (en) | 2022-12-01 | 2023-01-18 | Proqr Therapeutics Ii Bv | Antisense oligonucleotides for the treatment of aldehyde dehydrogenase 2 deficiency |
| WO2024121373A1 (en) | 2022-12-09 | 2024-06-13 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of cardiovascular disease |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014169206A2 (en) * | 2013-04-11 | 2014-10-16 | Carnegie Mellon University | Divalent nucleobase compounds and uses therefor |
| KR20220106232A (ko) * | 2014-01-16 | 2022-07-28 | 웨이브 라이프 사이언시스 리미티드 | 키랄 디자인 |
| NZ751483A (en) * | 2016-09-01 | 2022-07-01 | Proqr Therapeutics Ii Bv | Chemically modified single-stranded rna-editing oligonucleotides |
| US11718638B2 (en) * | 2017-06-21 | 2023-08-08 | Wave Life Sciences Ltd. | Compounds, compositions and methods for synthesis |
-
2020
- 2020-10-06 US US17/766,677 patent/US20230220384A1/en active Pending
- 2020-10-06 CN CN202080069504.2A patent/CN114585737A/zh active Pending
- 2020-10-06 KR KR1020227015085A patent/KR20220076508A/ko unknown
- 2020-10-06 MX MX2022004101A patent/MX2022004101A/es unknown
- 2020-10-06 CA CA3154768A patent/CA3154768A1/en active Pending
- 2020-10-06 WO PCT/US2020/054436 patent/WO2021071858A1/en active Application Filing
- 2020-10-06 BR BR112022006205A patent/BR112022006205A2/pt unknown
- 2020-10-06 AU AU2020363391A patent/AU2020363391A1/en active Pending
- 2020-10-06 EP EP20873624.9A patent/EP4022059A4/en active Pending
- 2020-10-06 JP JP2022520901A patent/JP2022551124A/ja active Pending
-
2022
- 2022-04-04 IL IL291933A patent/IL291933A/en unknown
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