JPWO2021055594A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021055594A5
JPWO2021055594A5 JP2022506595A JP2022506595A JPWO2021055594A5 JP WO2021055594 A5 JPWO2021055594 A5 JP WO2021055594A5 JP 2022506595 A JP2022506595 A JP 2022506595A JP 2022506595 A JP2022506595 A JP 2022506595A JP WO2021055594 A5 JPWO2021055594 A5 JP WO2021055594A5
Authority
JP
Japan
Prior art keywords
seq
polypeptide
amino acid
acid sequence
cys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022506595A
Other languages
English (en)
Japanese (ja)
Other versions
JP7756072B2 (ja
JP2022548472A5 (https=
JP2022548472A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/051255 external-priority patent/WO2021055594A1/en
Publication of JP2022548472A publication Critical patent/JP2022548472A/ja
Publication of JP2022548472A5 publication Critical patent/JP2022548472A5/ja
Publication of JPWO2021055594A5 publication Critical patent/JPWO2021055594A5/ja
Application granted granted Critical
Publication of JP7756072B2 publication Critical patent/JP7756072B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022506595A 2019-09-20 2020-09-17 T細胞調節ポリペプチド及びその使用方法 Active JP7756072B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962903441P 2019-09-20 2019-09-20
US62/903,441 2019-09-20
US202062990693P 2020-03-17 2020-03-17
US62/990,693 2020-03-17
US202063048561P 2020-07-06 2020-07-06
US63/048,561 2020-07-06
PCT/US2020/051255 WO2021055594A1 (en) 2019-09-20 2020-09-17 T-cell modulatory polypeptides and methods of use thereof

Publications (4)

Publication Number Publication Date
JP2022548472A JP2022548472A (ja) 2022-11-21
JP2022548472A5 JP2022548472A5 (https=) 2023-09-25
JPWO2021055594A5 true JPWO2021055594A5 (https=) 2023-09-25
JP7756072B2 JP7756072B2 (ja) 2025-10-17

Family

ID=74884186

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022506595A Active JP7756072B2 (ja) 2019-09-20 2020-09-17 T細胞調節ポリペプチド及びその使用方法

Country Status (11)

Country Link
US (2) US20220143063A1 (https=)
EP (1) EP4030897A4 (https=)
JP (1) JP7756072B2 (https=)
KR (1) KR20220066075A (https=)
CN (1) CN114423284A (https=)
AU (1) AU2020348373A1 (https=)
CA (1) CA3146591A1 (https=)
IL (1) IL290635A (https=)
MX (1) MX2022003367A (https=)
TW (1) TW202126683A (https=)
WO (1) WO2021055594A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116970059A (zh) 2016-12-22 2023-10-31 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
IL269000B2 (en) 2017-03-15 2024-06-01 Cue Biopharma Inc Methods for modulating an immune response
TW201920249A (zh) 2017-09-07 2019-06-01 美商信號生物製藥公司 具有結合位點之t細胞調節多聚體多肽及其使用方法
TWI856047B (zh) * 2018-12-19 2024-09-21 美商信號生物製藥公司 多聚體t細胞調節多肽及其使用方法
US12453774B2 (en) * 2019-11-07 2025-10-28 Genoimmune Therapeutics Co., Ltd. Tumor immunotherapy polypeptide and application thereof
TW202208395A (zh) 2020-05-12 2022-03-01 美商信號生物製藥公司 多聚體t細胞調節多肽及其使用方法
EP4211149A4 (en) 2020-09-09 2024-10-09 Cue Biopharma, Inc. MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF
US11421015B2 (en) 2020-12-07 2022-08-23 Think Therapeutics, Inc. Method of compact peptide vaccines using residue optimization
US11058751B1 (en) 2020-11-20 2021-07-13 Think Therapeutics, Inc. Compositions for optimized RAS peptide vaccines
CN116710115A (zh) 2020-11-20 2023-09-05 思维疗法股份有限公司 用于优化的肽疫苗的组合物和方法
US12275766B2 (en) * 2020-12-23 2025-04-15 Janssen Biotech, Inc. Neoantigen peptide mimics
JP2024512470A (ja) * 2021-03-19 2024-03-19 キュー バイオファーマ, インコーポレイテッド T細胞調節ポリペプチド及びその使用方法
US11464842B1 (en) 2021-04-28 2022-10-11 Think Therapeutics, Inc. Compositions and method for optimized peptide vaccines using residue optimization
CN119095882A (zh) * 2022-04-07 2024-12-06 Cue生物制药股份有限公司 免疫细胞结合多肽
CN115820736B (zh) * 2022-12-08 2024-05-10 西南大学 家蚕丝胶蛋白Ser4在提高蚕丝性能中的应用及其方法
WO2024264007A2 (en) * 2023-06-23 2024-12-26 Cue Biopharma, Inc. T-cell modulatory polypeptides and methods of use thereof
WO2024264004A2 (en) * 2023-06-23 2024-12-26 Cue Biopharma, Inc. T-cell modulatory polypeptides and methods of use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3157552T3 (pl) * 2014-06-18 2020-05-18 Albert Einstein College Of Medicine Polipeptydy syntac i ich zastosowania
CN115873129A (zh) * 2015-03-23 2023-03-31 约翰·霍普金斯大学 由体细胞突变基因编码的hla限制性表位
EP3408279A1 (en) * 2016-01-27 2018-12-05 CSL Behring Lengnau AG Recombinant igg fc multimers
CA3014458A1 (en) * 2016-03-02 2017-09-08 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
AU2017225787B2 (en) * 2016-03-03 2021-09-23 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
CA3019005A1 (en) * 2016-05-18 2017-11-23 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
CN116970059A (zh) * 2016-12-22 2023-10-31 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
US11851471B2 (en) * 2017-01-09 2023-12-26 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
IL269000B2 (en) * 2017-03-15 2024-06-01 Cue Biopharma Inc Methods for modulating an immune response
TW201920249A (zh) * 2017-09-07 2019-06-01 美商信號生物製藥公司 具有結合位點之t細胞調節多聚體多肽及其使用方法
WO2019139896A1 (en) * 2018-01-09 2019-07-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
WO2021230247A1 (ja) * 2020-05-12 2021-11-18 大日本住友製薬株式会社 癌を処置するための医薬組成物

Similar Documents

Publication Publication Date Title
JPWO2021055594A5 (https=)
US20230399415A1 (en) Twin Immune Cell Engager
JP2020514375A5 (https=)
JP2018525006A5 (https=)
CA3089333C (en) Anti-pdl1, il-15 and tgf-beta receptor combination molecules
CN110785435B (zh) 与il-12和il-18的基于il-15的融合物
JP6722189B2 (ja) 単量体Fcドメイン
EP3472205B1 (en) Chimeric antigen receptor
JP2020511949A5 (https=)
IL277398B1 (en) Pd-l1 binding affimers, and uses related thereto
JP2017519491A5 (https=)
CN110914308A (zh) 改进的双特异性多肽分子
JP2021500855A5 (https=)
CA3076099A1 (en) Linkers for chimeric antigen receptors
US20210269547A1 (en) Antibody tumor-targeting assembly complexes
JP2019525771A5 (https=)
JP7749319B2 (ja) Ctla-4変異型免疫調節タンパク質およびそれらの使用
RU2018109426A (ru) Химерные антигенные рецепторы со встроенными контролируемыми функциями
JP7783164B2 (ja) 改変インターロイキン2受容体ベータアゴニスト
JP2023512452A (ja) Bcma指向性細胞免疫療法組成物および方法
JPWO2020243315A5 (https=)
CN116981470A (zh) T细胞调节多肽和其使用方法
JPWO2021239812A5 (https=)
CA3146903A1 (en) Modified cytotoxic t cells and methods of use thereof
GB2619410A (en) Methods and compositions for cellular therapy