TW202126683A - Ｔ細胞調節多肽及其使用方法 - Google Patents
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Peptides Or Proteins (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US201962903441P | 2019-09-20 | 2019-09-20 | |
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| US202062990693P | 2020-03-17 | 2020-03-17 | |
| US62/990,693 | 2020-03-17 | ||
| US202063048561P | 2020-07-06 | 2020-07-06 | |
| US63/048,561 | 2020-07-06 |
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| TW202126683A true TW202126683A (zh) | 2021-07-16 |
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| TW109132369A TW202126683A (zh) | 2019-09-20 | 2020-09-18 | Ｔ細胞調節多肽及其使用方法 |
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| US (2) | US20220143063A1 (https=) |
| EP (1) | EP4030897A4 (https=) |
| JP (1) | JP7756072B2 (https=) |
| KR (1) | KR20220066075A (https=) |
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| MX (1) | MX2022003367A (https=) |
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| IL269000B2 (en) | 2017-03-15 | 2024-06-01 | Cue Biopharma Inc | Methods for modulating an immune response |
| TW201920249A (zh) | 2017-09-07 | 2019-06-01 | 美商信號生物製藥公司 | 具有結合位點之t細胞調節多聚體多肽及其使用方法 |
| TWI856047B (zh) * | 2018-12-19 | 2024-09-21 | 美商信號生物製藥公司 | 多聚體ｔ細胞調節多肽及其使用方法 |
| US12453774B2 (en) * | 2019-11-07 | 2025-10-28 | Genoimmune Therapeutics Co., Ltd. | Tumor immunotherapy polypeptide and application thereof |
| TW202208395A (zh) | 2020-05-12 | 2022-03-01 | 美商信號生物製藥公司 | 多聚體ｔ細胞調節多肽及其使用方法 |
| EP4211149A4 (en) | 2020-09-09 | 2024-10-09 | Cue Biopharma, Inc. | MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF |
| US11421015B2 (en) | 2020-12-07 | 2022-08-23 | Think Therapeutics, Inc. | Method of compact peptide vaccines using residue optimization |
| US11058751B1 (en) | 2020-11-20 | 2021-07-13 | Think Therapeutics, Inc. | Compositions for optimized RAS peptide vaccines |
| CN116710115A (zh) | 2020-11-20 | 2023-09-05 | 思维疗法股份有限公司 | 用于优化的肽疫苗的组合物和方法 |
| US12275766B2 (en) * | 2020-12-23 | 2025-04-15 | Janssen Biotech, Inc. | Neoantigen peptide mimics |
| JP2024512470A (ja) * | 2021-03-19 | 2024-03-19 | キュー バイオファーマ， インコーポレイテッド | Ｔ細胞調節ポリペプチド及びその使用方法 |
| US11464842B1 (en) | 2021-04-28 | 2022-10-11 | Think Therapeutics, Inc. | Compositions and method for optimized peptide vaccines using residue optimization |
| CN119095882A (zh) * | 2022-04-07 | 2024-12-06 | Cue生物制药股份有限公司 | 免疫细胞结合多肽 |
| CN115820736B (zh) * | 2022-12-08 | 2024-05-10 | 西南大学 | 家蚕丝胶蛋白Ser4在提高蚕丝性能中的应用及其方法 |
| WO2024264007A2 (en) * | 2023-06-23 | 2024-12-26 | Cue Biopharma, Inc. | T-cell modulatory polypeptides and methods of use thereof |
| WO2024264004A2 (en) * | 2023-06-23 | 2024-12-26 | Cue Biopharma, Inc. | T-cell modulatory polypeptides and methods of use thereof |
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| PL3157552T3 (pl) * | 2014-06-18 | 2020-05-18 | Albert Einstein College Of Medicine | Polipeptydy syntac i ich zastosowania |
| CN115873129A (zh) * | 2015-03-23 | 2023-03-31 | 约翰·霍普金斯大学 | 由体细胞突变基因编码的hla限制性表位 |
| EP3408279A1 (en) * | 2016-01-27 | 2018-12-05 | CSL Behring Lengnau AG | Recombinant igg fc multimers |
| CA3014458A1 (en) * | 2016-03-02 | 2017-09-08 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| AU2017225787B2 (en) * | 2016-03-03 | 2021-09-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CA3019005A1 (en) * | 2016-05-18 | 2017-11-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CN116970059A (zh) * | 2016-12-22 | 2023-10-31 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
| US11851471B2 (en) * | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| IL269000B2 (en) * | 2017-03-15 | 2024-06-01 | Cue Biopharma Inc | Methods for modulating an immune response |
| TW201920249A (zh) * | 2017-09-07 | 2019-06-01 | 美商信號生物製藥公司 | 具有結合位點之t細胞調節多聚體多肽及其使用方法 |
| WO2019139896A1 (en) * | 2018-01-09 | 2019-07-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| WO2021230247A1 (ja) * | 2020-05-12 | 2021-11-18 | 大日本住友製薬株式会社 | 癌を処置するための医薬組成物 |
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| IL290635A (en) | 2022-04-01 |
| CN114423284A (zh) | 2022-04-29 |
| US20220143063A1 (en) | 2022-05-12 |
| JP7756072B2 (ja) | 2025-10-17 |
| US20250120996A1 (en) | 2025-04-17 |
| CA3146591A1 (en) | 2021-03-25 |
| EP4030897A4 (en) | 2023-10-18 |
| KR20220066075A (ko) | 2022-05-23 |
| WO2021055594A1 (en) | 2021-03-25 |
| MX2022003367A (es) | 2022-04-11 |
| AU2020348373A1 (en) | 2022-02-24 |
| JP2022548472A (ja) | 2022-11-21 |
| EP4030897A1 (en) | 2022-07-27 |
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