JPWO2021024906A5 - - Google Patents
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- Publication number
- JPWO2021024906A5 JPWO2021024906A5 JP2021537269A JP2021537269A JPWO2021024906A5 JP WO2021024906 A5 JPWO2021024906 A5 JP WO2021024906A5 JP 2021537269 A JP2021537269 A JP 2021537269A JP 2021537269 A JP2021537269 A JP 2021537269A JP WO2021024906 A5 JPWO2021024906 A5 JP WO2021024906A5
- Authority
- JP
- Japan
- Prior art keywords
- prevention
- treatment
- hydrophilic
- hydrophobic
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002265 prevention Effects 0.000 claims 12
- 229920001577 copolymer Polymers 0.000 claims 10
- 239000002105 nanoparticle Substances 0.000 claims 6
- 230000001629 suppression Effects 0.000 claims 6
- 206010009900 Colitis ulcerative Diseases 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 208000008589 Obesity Diseases 0.000 claims 5
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 208000019425 cirrhosis of liver Diseases 0.000 claims 5
- 206010012601 diabetes mellitus Diseases 0.000 claims 5
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 claims 5
- 235000020824 obesity Nutrition 0.000 claims 5
- 230000005855 radiation Effects 0.000 claims 5
- 238000001959 radiotherapy Methods 0.000 claims 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 4
- 206010020575 Hyperammonaemia Diseases 0.000 claims 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 3
- 230000002209 hydrophobic effect Effects 0.000 claims 3
- 125000001424 substituent group Chemical group 0.000 claims 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 229910021529 ammonia Inorganic materials 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical group OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 239000000693 micelle Substances 0.000 claims 1
- -1 phenethylamino group Chemical group 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019143619 | 2019-08-05 | ||
| JP2019143619 | 2019-08-05 | ||
| PCT/JP2020/029239 WO2021024906A1 (ja) | 2019-08-05 | 2020-07-30 | 短鎖脂肪酸エステルを担持する親水－疎水性共重合体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021024906A1 JPWO2021024906A1 (https=) | 2021-02-11 |
| JPWO2021024906A5 true JPWO2021024906A5 (https=) | 2022-06-23 |
| JP7548586B2 JP7548586B2 (ja) | 2024-09-10 |
Family
ID=74503809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021537269A Active JP7548586B2 (ja) | 2019-08-05 | 2020-07-30 | 短鎖脂肪酸エステルを担持する親水－疎水性共重合体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220332876A1 (https=) |
| EP (1) | EP4011444A4 (https=) |
| JP (1) | JP7548586B2 (https=) |
| CN (1) | CN114430756B (https=) |
| AU (1) | AU2020324649B8 (https=) |
| CA (1) | CA3152003A1 (https=) |
| WO (1) | WO2021024906A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025069980A1 (ja) | 2023-09-28 | 2025-04-03 | 国立大学法人筑波大学 | ジクロロ酢酸を側鎖に担持する親水－疎水性共重合体及びそれらの医療用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4212768A1 (de) * | 1992-04-16 | 1993-10-21 | Huels Chemische Werke Ag | Verfahren zur Herstellung von wäßrigen Polymerdispersionen |
| JP3228482B2 (ja) * | 1992-06-29 | 2001-11-12 | 株式会社クラレ | 分散安定剤および水性分散液 |
| DE60041978D1 (de) * | 1999-11-15 | 2009-05-20 | Biocure Inc | Auf äussere bedingungen ansprechende polymere hohle partikel |
| US20070122443A1 (en) * | 2005-11-29 | 2007-05-31 | Narayanan Pallassana V | Amphiphilic copolymer compositions |
| JP5737705B2 (ja) | 2008-05-02 | 2015-06-17 | 国立大学法人 筑波大学 | 高分子化環状ニトロキシドラジカル化合物およびその使用 |
| US10208152B2 (en) | 2014-09-30 | 2019-02-19 | University Of Tsukuba | Poly(ethylene glycol)-b-poly(halomethylstyrene), derivative thereof, and method for producing same |
| US12049543B2 (en) * | 2017-01-19 | 2024-07-30 | Crestecbio Inc. | Copolymer containing cyclic nitroxide radical and trialkoxysilyl in side chain, and use thereof |
| EP3612570A4 (en) * | 2017-04-17 | 2021-01-13 | The University of Chicago | POLYMERIC MATERIALS FOR THE ADMINISTRATION OF SHORT-CHAIN FATTY ACIDS TO THE INTESTINE FOR HUMAN HEALTH AND DISEASE TREATMENT APPLICATIONS |
| JP7116428B2 (ja) * | 2017-06-19 | 2022-08-10 | 国立大学法人 筑波大学 | 感染症治療薬 |
| JPWO2019208617A1 (ja) * | 2018-04-27 | 2021-05-13 | 国立大学法人 筑波大学 | ソラフェニブの経口デリバリー用組成物及びその使用 |
-
2020
- 2020-07-30 AU AU2020324649A patent/AU2020324649B8/en not_active Expired - Fee Related
- 2020-07-30 WO PCT/JP2020/029239 patent/WO2021024906A1/ja not_active Ceased
- 2020-07-30 CA CA3152003A patent/CA3152003A1/en active Pending
- 2020-07-30 EP EP20848934.4A patent/EP4011444A4/en active Pending
- 2020-07-30 JP JP2021537269A patent/JP7548586B2/ja active Active
- 2020-07-30 CN CN202080069272.0A patent/CN114430756B/zh active Active
- 2020-07-30 US US17/631,593 patent/US20220332876A1/en not_active Abandoned
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