JPWO2021009684A5 - - Google Patents
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- Publication number
- JPWO2021009684A5 JPWO2021009684A5 JP2022502928A JP2022502928A JPWO2021009684A5 JP WO2021009684 A5 JPWO2021009684 A5 JP WO2021009684A5 JP 2022502928 A JP2022502928 A JP 2022502928A JP 2022502928 A JP2022502928 A JP 2022502928A JP WO2021009684 A5 JPWO2021009684 A5 JP WO2021009684A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- composition
- seq
- acid sequence
- capsid protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2023505 | 2019-07-15 | ||
| NL2023505 | 2019-07-15 | ||
| PCT/IB2020/056635 WO2021009684A1 (en) | 2019-07-15 | 2020-07-15 | Modified aav capsid proteins for treatment of arthritic disease |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022541520A JP2022541520A (ja) | 2022-09-26 |
| JPWO2021009684A5 true JPWO2021009684A5 (https=) | 2023-07-21 |
| JP2022541520A5 JP2022541520A5 (https=) | 2023-07-21 |
| JP7681277B2 JP7681277B2 (ja) | 2025-05-22 |
Family
ID=68425203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502928A Active JP7681277B2 (ja) | 2019-07-15 | 2020-07-15 | 関節炎疾患の治療のための修飾ａａｖキャプシドタンパク質 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20220267797A1 (https=) |
| EP (1) | EP3999119B1 (https=) |
| JP (1) | JP7681277B2 (https=) |
| KR (1) | KR20220081971A (https=) |
| CN (1) | CN114502737B (https=) |
| AU (1) | AU2020314883A1 (https=) |
| BR (1) | BR112022000724A2 (https=) |
| CA (1) | CA3146791A1 (https=) |
| DK (1) | DK3999119T3 (https=) |
| ES (1) | ES2998884T3 (https=) |
| FI (1) | FI3999119T3 (https=) |
| HR (1) | HRP20241647T1 (https=) |
| HU (1) | HUE069369T2 (https=) |
| IL (1) | IL289826A (https=) |
| LT (1) | LT3999119T (https=) |
| MX (1) | MX2022000551A (https=) |
| PH (1) | PH12022550109A1 (https=) |
| PL (1) | PL3999119T3 (https=) |
| PT (1) | PT3999119T (https=) |
| RS (1) | RS66255B1 (https=) |
| SI (1) | SI3999119T1 (https=) |
| SM (1) | SMT202400486T1 (https=) |
| WO (1) | WO2021009684A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202006056RA (en) * | 2018-01-17 | 2020-07-29 | Meiragtx Uk Ii Ltd | A modified raav capsid protein for gene therapy |
| MX2024004217A (es) | 2021-10-08 | 2024-06-26 | Dyno Therapeutics Inc | Variantes de cápside y métodos de uso de estas. |
| IL313832A (en) * | 2021-12-28 | 2024-08-01 | Chengdu Origen Biotechnology Co Ltd | Modified AAV capsid protein and its use |
| TW202502803A (zh) | 2023-03-10 | 2025-01-16 | 美商戴諾治療公司 | 衣殼多肽及其使用方法 |
| CN121311235A (zh) | 2023-04-13 | 2026-01-09 | 梅里特斯基因调控有限公司 | 炎症诱导型启动子 |
| TW202525832A (zh) | 2023-08-31 | 2025-07-01 | 美商戴諾治療公司 | 衣殼多肽及其使用方法(二) |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| WO2003042361A2 (en) | 2001-11-09 | 2003-05-22 | Government Of The United States Of America, Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| WO2006110689A2 (en) * | 2005-04-07 | 2006-10-19 | The Trustees Of The University Of Pennsylvania | Method of increasing the function of an aav vector |
| EP2311967B1 (en) | 2005-10-20 | 2017-09-20 | UniQure IP B.V. | Improved AAV vectors produced in insect cells |
| KR101589259B1 (ko) | 2006-06-21 | 2016-02-01 | 유니큐어 아이피 비.브이. | 곤충세포 내 ａａｖ의 생산에 유용한 ａａｖ-ｒｅｐ78의 번역을 위한 변형된 개시 코돈을 갖는 벡터 |
| ES2385679T3 (es) | 2006-08-24 | 2012-07-30 | Virovek, Inc. | Expresión de células de insecto de genes con marcos de lectura abiertos superpuestos, métodos y composiciones de éstos |
| EP2012122A1 (en) * | 2007-07-06 | 2009-01-07 | Medigene AG | Mutated parvovirus structural proteins as vaccines |
| SI3093345T1 (sl) | 2007-07-26 | 2019-08-30 | Uniqure Ip B.V. | Bakulovirusni vektorji, ki vsebujejo ponavljajoča kodirna zaporedja z različnimi kodonskimi preferencami |
| EP3257937B1 (en) | 2008-02-19 | 2022-08-03 | uniQure IP B.V. | Optimisation of expression of parvoviral rep and cap proteins in insect cells |
| WO2009154452A1 (en) | 2008-06-17 | 2009-12-23 | Amsterdam Molecular Therapeutics B.V. | Parvoviral capsid with incorporated Gly-Ala repeat region |
| WO2011112089A2 (en) | 2010-03-11 | 2011-09-15 | Amsterdam Molecular Therapeutics (Amt) Ip B.V. | Mutated rep encoding sequences for use in aav production |
| PT2744895E (pt) | 2011-09-08 | 2016-02-08 | Uniqure Ip Bv | Remoção de vírus contaminantes de preparações de aav |
| WO2013174760A1 (en) * | 2012-05-25 | 2013-11-28 | Deutsches Krebsforschungszentrum | Optimized aav-vectors for high transduction rates in dendritic cells |
| GB201403684D0 (en) * | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| IL248102B (en) * | 2014-05-02 | 2022-07-01 | Genzyme Corp | aav vectors for gene therapy of the central nervous system and retina |
| CN107002096A (zh) | 2014-10-06 | 2017-08-01 | 阿罗根有限公司 | 基于aav的基因疗法 |
| FI3445773T3 (fi) * | 2016-05-13 | 2023-03-30 | 4D Molecular Therapeutics Inc | Adenoassosioituneen viruksen kapsidimuunnoksia ja niiden käyttömenetelmiä |
| CN109843306A (zh) | 2016-08-19 | 2019-06-04 | 卡琳缪恩股份有限公司 | 使用自身互补型重组腺相关病毒治疗病症的方法和组合物 |
| KR20250121159A (ko) | 2016-12-07 | 2025-08-11 | 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 | 인터류킨-1 수용체 길항제(IL-1RA) cDNA |
| US20200370039A1 (en) * | 2017-04-11 | 2020-11-26 | Ruprecht-Karls-Universitat Heidelberg | Adeno-associated virus library |
| SG11202006056RA (en) * | 2018-01-17 | 2020-07-29 | Meiragtx Uk Ii Ltd | A modified raav capsid protein for gene therapy |
-
2020
- 2020-07-15 PL PL20740418.7T patent/PL3999119T3/pl unknown
- 2020-07-15 RS RS20241346A patent/RS66255B1/sr unknown
- 2020-07-15 MX MX2022000551A patent/MX2022000551A/es unknown
- 2020-07-15 AU AU2020314883A patent/AU2020314883A1/en not_active Abandoned
- 2020-07-15 ES ES20740418T patent/ES2998884T3/es active Active
- 2020-07-15 FI FIEP20740418.7T patent/FI3999119T3/fi active
- 2020-07-15 PH PH1/2022/550109A patent/PH12022550109A1/en unknown
- 2020-07-15 LT LTEPPCT/IB2020/056635T patent/LT3999119T/lt unknown
- 2020-07-15 JP JP2022502928A patent/JP7681277B2/ja active Active
- 2020-07-15 BR BR112022000724A patent/BR112022000724A2/pt unknown
- 2020-07-15 SI SI202030519T patent/SI3999119T1/sl unknown
- 2020-07-15 HU HUE20740418A patent/HUE069369T2/hu unknown
- 2020-07-15 WO PCT/IB2020/056635 patent/WO2021009684A1/en not_active Ceased
- 2020-07-15 EP EP20740418.7A patent/EP3999119B1/en active Active
- 2020-07-15 HR HRP20241647TT patent/HRP20241647T1/hr unknown
- 2020-07-15 CA CA3146791A patent/CA3146791A1/en active Pending
- 2020-07-15 DK DK20740418.7T patent/DK3999119T3/da active
- 2020-07-15 SM SM20240486T patent/SMT202400486T1/it unknown
- 2020-07-15 US US17/627,364 patent/US20220267797A1/en active Pending
- 2020-07-15 KR KR1020227004437A patent/KR20220081971A/ko active Pending
- 2020-07-15 PT PT207404187T patent/PT3999119T/pt unknown
- 2020-07-15 CN CN202080064732.0A patent/CN114502737B/zh active Active
-
2022
- 2022-01-13 IL IL289826A patent/IL289826A/en unknown
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