JPWO2020239568A5 - - Google Patents
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- Publication number
- JPWO2020239568A5 JPWO2020239568A5 JP2021569359A JP2021569359A JPWO2020239568A5 JP WO2020239568 A5 JPWO2020239568 A5 JP WO2020239568A5 JP 2021569359 A JP2021569359 A JP 2021569359A JP 2021569359 A JP2021569359 A JP 2021569359A JP WO2020239568 A5 JPWO2020239568 A5 JP WO2020239568A5
- Authority
- JP
- Japan
- Prior art keywords
- etoh
- methanesulfonylphenoxy
- fluoro
- propyl
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- OSBPYFBXSLJHCR-UHFFFAOYSA-N n-[2-(3-fluoro-5-methylsulfonylphenoxy)ethyl]propan-1-amine Chemical compound CCCNCCOC1=CC(F)=CC(S(C)(=O)=O)=C1 OSBPYFBXSLJHCR-UHFFFAOYSA-N 0.000 description 3
- 239000002002 slurry Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000012065 filter cake Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19176514.8 | 2019-05-24 | ||
| EP19176514 | 2019-05-24 | ||
| EP20166361 | 2020-03-27 | ||
| EP20166361.4 | 2020-03-27 | ||
| PCT/EP2020/064046 WO2020239568A1 (en) | 2019-05-24 | 2020-05-20 | Pharmaceutically acceptable salts of [2-(3-fluoro-5-methane-sulfonylphenoxy)ethyl](propyl)amine and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022533433A JP2022533433A (ja) | 2022-07-22 |
| JPWO2020239568A5 true JPWO2020239568A5 (enrdf_load_stackoverflow) | 2023-05-29 |
| JP7623958B2 JP7623958B2 (ja) | 2025-01-29 |
Family
ID=70682855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569359A Active JP7623958B2 (ja) | 2019-05-24 | 2020-05-20 | ［２－（３－フルオロ－５－メタンスルホニルフェノキシ）エチル］（プロピル）アミンの薬学的に許容される塩、およびその使用 |
Country Status (21)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220011638A (ko) | 2019-05-24 | 2022-01-28 | 인터그레이티브 리서치 래버러토리즈 스웨덴 에이비 | [2-(3-플루오로-5-메탄-술포닐페녹시)에틸](프로필)아민의 제약상 허용되는 염 및 그의 용도 |
| JP2023548429A (ja) * | 2020-11-10 | 2023-11-16 | インテグレイティブ・リサーチ・ラボラトリーズ・スウェーデン・アーベー | パーキンソン病、特にｌ－ｄｏｐａ誘発性ジスキネジアのための医薬品に対する感作の予防または軽減における使用のための［２－（３－フルオロ－５－メタンスルホニルフェノキシ）エチル］（プロピル）アミン（メスドペタム） |
| EP4577201A1 (en) * | 2022-08-24 | 2025-07-02 | Alkem Laboratories Limited | Mesdopetam compositions |
| IL319769A (en) | 2022-09-21 | 2025-05-01 | Assia Chem Ind Ltd | Solid forms of mesodoptam and its salts |
| GB202312055D0 (en) * | 2023-08-07 | 2023-09-20 | Ipsen Biopharm Ltd | Pharmaceutical compositions |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51123821A (en) | 1975-04-18 | 1976-10-28 | Nippon Kayaku Co Ltd | An algicide and protective agent |
| US4128574A (en) * | 1976-10-04 | 1978-12-05 | General Electric Company | Method for making organic polycarboxylic acids |
| GB8823405D0 (en) | 1988-10-05 | 1988-11-09 | Erba Carlo Spa | Aryloxy-arythio-heteraryloxy-heteroarylthio-alkenylene derivatives of amines |
| EP1123933A1 (en) | 1994-10-14 | 2001-08-16 | MERCK PATENT GmbH | 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chromane as CNS active agent |
| SE9904723D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| DOP2001000189A (es) | 2000-06-30 | 2002-03-30 | Pfizer Prod Inc | Benzofenonas y sulfonas como inhibidores de la captación de glicina |
| JP2006193494A (ja) | 2005-01-17 | 2006-07-27 | Dainippon Ink & Chem Inc | ４級アンモニウム系化合物を有効成分とする心臓疾患治療剤 |
| US20100069346A1 (en) | 2005-06-23 | 2010-03-18 | Sara Holmqvist | New Azetidine Derivatives as Neurokinin Receptor Antagonists for the Treatment of Gastrointestinal Diseases |
| JP5210637B2 (ja) | 2005-11-29 | 2013-06-12 | キッセイ薬品工業株式会社 | 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途 |
| WO2007072041A1 (en) | 2005-12-23 | 2007-06-28 | Astex Therapeutics Limited | Therapeutic compounds |
| JP2009526844A (ja) * | 2006-02-15 | 2009-07-23 | 株式会社エムズサイエンス | ピペラジン誘導体 |
| CA2687721A1 (en) * | 2007-06-08 | 2008-12-18 | Arena Pharmaceuticals, Inc. | Crystalline forms of (r)-1-{2-[4'-(3-methoxy-propane-1-sulfonyl)-biphenyl-4-yl]-ethyl}-2-methyl-pyrrolidine, and compositions, and methods related thereto |
| TW200932225A (en) * | 2007-12-14 | 2009-08-01 | Lundbeck & Co As H | 4-[2,3-difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine |
| EP2271634B1 (en) | 2008-04-29 | 2014-02-12 | Integrative Research Laboratories Sweden AB | Modulators of dopamine neurotransmission |
| US20110105462A1 (en) | 2008-04-29 | 2011-05-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
| JP5548853B2 (ja) | 2008-04-29 | 2014-07-16 | インテグレイティブ・リサーチ・ラボラトリーズ・スウェーデン・アーベー | ドーパミン神経伝達のモジュレーター |
| WO2012143337A1 (en) | 2011-04-19 | 2012-10-26 | Neurosearch A/S | Novel modulators of cortical dopaminergic- and nmda-receptor-mediated glutamatergic neurotransmission |
| US9796673B2 (en) | 2014-12-22 | 2017-10-24 | Teva Pharmaceuticals International Gmbh | L-tartrate salt of pridopidine |
| RU2018131500A (ru) | 2016-02-08 | 2020-03-10 | Мерк Патент Гмбх | Кристаллические модификации гидрохлорида n-(4,5-бисметансульфонил-2-метилбензоил)гуанидина и солей n-(4,5-бисметансульфонил-2-метилбензоил)гуанидина |
| CN110621659B (zh) | 2017-05-19 | 2023-02-28 | 综合研究实验室瑞典股份公司 | (+)-3-(2,3-二氟苯基)-3-甲氧基吡咯烷或其药学上可接受的盐、其制备方法及其用途 |
| BR112020002227A2 (pt) * | 2017-08-07 | 2020-07-28 | Suven Life Sciences Limited | compostos de fluoropiperidina como antagonistas do receptor 5-ht6 puro |
| WO2020110128A1 (en) | 2018-11-29 | 2020-06-04 | Prilenia Neurotherapeutics Ltd. | Combination of pridopidine and an additional therapeutic agent for treating drug induced dyskinesia |
| KR20220011638A (ko) | 2019-05-24 | 2022-01-28 | 인터그레이티브 리서치 래버러토리즈 스웨덴 에이비 | [2-(3-플루오로-5-메탄-술포닐페녹시)에틸](프로필)아민의 제약상 허용되는 염 및 그의 용도 |
-
2020
- 2020-05-20 KR KR1020217037818A patent/KR20220011638A/ko active Pending
- 2020-05-20 CA CA3140805A patent/CA3140805A1/en active Pending
- 2020-05-20 WO PCT/EP2020/064046 patent/WO2020239568A1/en not_active Ceased
- 2020-05-20 CN CN202080036829.0A patent/CN113853369B/zh active Active
- 2020-05-20 US US17/612,902 patent/US12275694B2/en active Active
- 2020-05-20 EP EP20725728.8A patent/EP3976581B1/en active Active
- 2020-05-20 SG SG11202112165QA patent/SG11202112165QA/en unknown
- 2020-05-20 EP EP23190702.3A patent/EP4292653A3/en active Pending
- 2020-05-20 BR BR112021023563A patent/BR112021023563A2/pt unknown
- 2020-05-20 FI FIEP20725728.8T patent/FI3976581T3/fi active
- 2020-05-20 JO JOP/2021/0312A patent/JOP20210312A1/ar unknown
- 2020-05-20 PH PH1/2021/552844A patent/PH12021552844A1/en unknown
- 2020-05-20 PT PT207257288T patent/PT3976581T/pt unknown
- 2020-05-20 MX MX2021014271A patent/MX2021014271A/es unknown
- 2020-05-20 DK DK20725728.8T patent/DK3976581T3/da active
- 2020-05-20 JP JP2021569359A patent/JP7623958B2/ja active Active
- 2020-05-20 ES ES20725728T patent/ES2970361T3/es active Active
- 2020-05-20 PL PL20725728.8T patent/PL3976581T3/pl unknown
- 2020-05-20 IL IL288271A patent/IL288271B2/en unknown
- 2020-05-20 AU AU2020286003A patent/AU2020286003B2/en active Active
-
2021
- 2021-11-24 CL CL2021003115A patent/CL2021003115A1/es unknown
- 2021-12-06 CO CONC2021/0016556A patent/CO2021016556A2/es unknown
-
2025
- 2025-03-14 US US19/080,430 patent/US20250243155A1/en active Pending
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