JPWO2020207991A5 - - Google Patents
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- Publication number
- JPWO2020207991A5 JPWO2020207991A5 JP2021559754A JP2021559754A JPWO2020207991A5 JP WO2020207991 A5 JPWO2020207991 A5 JP WO2020207991A5 JP 2021559754 A JP2021559754 A JP 2021559754A JP 2021559754 A JP2021559754 A JP 2021559754A JP WO2020207991 A5 JPWO2020207991 A5 JP WO2020207991A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- hexahydro
- pyrazino
- amino
- carbonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2019/081900 | 2019-04-09 | ||
| CN2019081900 | 2019-04-09 | ||
| CNPCT/CN2019/121598 | 2019-11-28 | ||
| CN2019121598 | 2019-11-28 | ||
| CN2020078225 | 2020-03-06 | ||
| CNPCT/CN2020/078225 | 2020-03-06 | ||
| PCT/EP2020/059831 WO2020207991A1 (en) | 2019-04-09 | 2020-04-07 | Hexahydro-1h-pyrazino[1,2-a]pyrazine compounds for the treatment of autoimmune disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022527588A JP2022527588A (ja) | 2022-06-02 |
| JPWO2020207991A5 true JPWO2020207991A5 (zh) | 2023-04-10 |
Family
ID=70228042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021559754A Pending JP2022527588A (ja) | 2019-04-09 | 2020-04-07 | 自己免疫疾患の治療のためのヘキサヒドロ－１Ｈ－ピラジノ［１，２－ａ］ピラジン化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20220340597A1 (zh) |
| EP (1) | EP3953356B1 (zh) |
| JP (1) | JP2022527588A (zh) |
| KR (1) | KR20210149163A (zh) |
| CN (1) | CN113710672A (zh) |
| AU (1) | AU2020272467A1 (zh) |
| BR (1) | BR112021020297A2 (zh) |
| CA (1) | CA3135129A1 (zh) |
| CL (1) | CL2021002621A1 (zh) |
| CO (1) | CO2021013166A2 (zh) |
| CR (1) | CR20210513A (zh) |
| IL (1) | IL286870A (zh) |
| MA (1) | MA55594A (zh) |
| MX (1) | MX2021012223A (zh) |
| PE (1) | PE20212178A1 (zh) |
| SG (1) | SG11202110401WA (zh) |
| TW (1) | TW202104230A (zh) |
| WO (1) | WO2020207991A1 (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114599652B (zh) * | 2019-10-31 | 2024-07-12 | 豪夫迈·罗氏有限公司 | 用于治疗自身免疫性疾病的氢吡嗪并[1,2-d][1,4]二氮杂䓬化合物 |
| US20230002375A1 (en) * | 2019-11-12 | 2023-01-05 | Hoffmann-La Roche Inc. | Hydropyrazino[1,2-b]isoquinoline compounds for the treatment of autoimmune disease |
| PE20231098A1 (es) | 2019-11-28 | 2023-07-18 | Bayer Ag | Aminoquinolonas sustituidas como inhibidores de dgk alfa para la activacion inmune |
| EP4069693B1 (en) * | 2019-12-03 | 2024-03-20 | F. Hoffmann-La Roche AG | Hydropyrido[1,2-alpha]pyrazine compounds for the treatment of autoimmune diseases |
| WO2022013136A1 (en) * | 2020-07-14 | 2022-01-20 | F. Hoffmann-La Roche Ag | Hydroisoquinoline or hydronaphthyridine compounds for the treatment of autoimmune disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2663555T (pt) * | 2011-01-12 | 2017-03-23 | Array Biopharma Inc | Benzoazepinas substituídas como moduladores de recetores tipo-toll |
| PE20150735A1 (es) | 2012-09-14 | 2015-05-17 | Hoffmann La Roche | Derivados de pirazol-carboxamida como moduladores de taar para uso en el tratamiento de numerosos desordenes, tales como depresion, diabetes y enfermedad de parkinson |
| CA2933466A1 (en) * | 2013-12-13 | 2015-06-18 | Takeda Pharmaceutical Company Limited | Pyrrolo[3,2-c]pyridine derivatives as tlr inhibitors |
| SI3889145T1 (sl) * | 2015-12-17 | 2024-05-31 | Merck Patent Gmbh | 8-ciano-5-piperidino-kinolini kot antagonisti tlr7/8 in njihove uporabe za zdravljenje imunskih motenj |
| EP3807271A1 (en) * | 2018-06-13 | 2021-04-21 | F. Hoffmann-La Roche AG | Pyridinyl heterocyclyl compounds for the treatment of autoimmune disease |
| WO2020064792A1 (en) * | 2018-09-27 | 2020-04-02 | F. Hoffmann-La Roche Ag | Heterocyclyl compounds for the treatment of autoimmune disease |
-
2020
- 2020-04-07 KR KR1020217036391A patent/KR20210149163A/ko unknown
- 2020-04-07 MX MX2021012223A patent/MX2021012223A/es unknown
- 2020-04-07 MA MA055594A patent/MA55594A/fr unknown
- 2020-04-07 CA CA3135129A patent/CA3135129A1/en active Pending
- 2020-04-07 US US17/602,057 patent/US20220340597A1/en active Pending
- 2020-04-07 AU AU2020272467A patent/AU2020272467A1/en not_active Abandoned
- 2020-04-07 PE PE2021001647A patent/PE20212178A1/es unknown
- 2020-04-07 BR BR112021020297A patent/BR112021020297A2/pt not_active Application Discontinuation
- 2020-04-07 EP EP20717841.9A patent/EP3953356B1/en active Active
- 2020-04-07 CN CN202080030189.2A patent/CN113710672A/zh active Pending
- 2020-04-07 SG SG11202110401WA patent/SG11202110401WA/en unknown
- 2020-04-07 JP JP2021559754A patent/JP2022527588A/ja active Pending
- 2020-04-07 WO PCT/EP2020/059831 patent/WO2020207991A1/en active Application Filing
- 2020-04-07 CR CR20210513A patent/CR20210513A/es unknown
- 2020-04-08 TW TW109111749A patent/TW202104230A/zh unknown
-
2021
- 2021-09-30 CO CONC2021/0013166A patent/CO2021013166A2/es unknown
- 2021-09-30 IL IL286870A patent/IL286870A/en unknown
- 2021-10-06 CL CL2021002621A patent/CL2021002621A1/es unknown
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