JPWO2019233941A5 - - Google Patents
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- Publication number
- JPWO2019233941A5 JPWO2019233941A5 JP2020567772A JP2020567772A JPWO2019233941A5 JP WO2019233941 A5 JPWO2019233941 A5 JP WO2019233941A5 JP 2020567772 A JP2020567772 A JP 2020567772A JP 2020567772 A JP2020567772 A JP 2020567772A JP WO2019233941 A5 JPWO2019233941 A5 JP WO2019233941A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- amino
- pyrazino
- tetrahydro
- carbonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018090004 | 2018-06-05 | ||
| CNPCT/CN2018/090004 | 2018-06-05 | ||
| EP18193916.6 | 2018-09-12 | ||
| EP18193916 | 2018-09-12 | ||
| CNPCT/CN2019/086019 | 2019-05-08 | ||
| CN2019086019 | 2019-05-08 | ||
| PCT/EP2019/064323 WO2019233941A1 (en) | 2018-06-05 | 2019-06-03 | Tetrahydro-1 h-pyrazino[2,1 -ajisoindolylquinoline compounds for the treatment of autoimmune disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021527041A JP2021527041A (ja) | 2021-10-11 |
| JPWO2019233941A5 true JPWO2019233941A5 (zh) | 2023-07-11 |
| JP7374130B2 JP7374130B2 (ja) | 2023-11-06 |
Family
ID=66793968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567772A Active JP7374130B2 (ja) | 2018-06-05 | 2019-06-03 | 自己免疫疾患治療用の新規なテトラヒドロ－１Ｈ－ピラジノ［２，１－ａ］イソインドリルキノリン化合物 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20210371432A1 (zh) |
| EP (1) | EP3802539B1 (zh) |
| JP (1) | JP7374130B2 (zh) |
| KR (1) | KR20210018818A (zh) |
| CN (1) | CN112204028B (zh) |
| AU (1) | AU2019280728A1 (zh) |
| BR (1) | BR112020024782A2 (zh) |
| CA (1) | CA3098291A1 (zh) |
| CL (1) | CL2020003065A1 (zh) |
| CO (1) | CO2020014677A2 (zh) |
| CR (1) | CR20200584A (zh) |
| IL (1) | IL279144A (zh) |
| MA (1) | MA52747A (zh) |
| MX (1) | MX2020012827A (zh) |
| PE (1) | PE20210131A1 (zh) |
| PH (1) | PH12020552092A1 (zh) |
| SG (1) | SG11202011137SA (zh) |
| TW (1) | TW202016111A (zh) |
| WO (1) | WO2019233941A1 (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021094301A1 (en) * | 2019-11-12 | 2021-05-20 | F. Hoffmann-La Roche Ag | Hydropyrazino[1,2-b]isoquinoline compounds for the treatment of autoimmune disease |
| JP2023502087A (ja) * | 2019-11-19 | 2023-01-20 | エフ．ホフマン－ラ ロシュ アーゲー | 自己免疫疾患の処置のためのヒドロ－１Ｈ－ピロロ［１，２－ａ］ピラジン化合物 |
| WO2021099285A1 (en) * | 2019-11-19 | 2021-05-27 | F. Hoffmann-La Roche Ag | Triazatricycle compounds for the treatment of autoimmune disease |
| JP2023533807A (ja) | 2020-07-14 | 2023-08-04 | エフ． ホフマン－ラ ロシュ アーゲー | 自己免疫疾患の処置のためのヒドロイソキノリン又はヒドロナフチリジン化合物 |
| TW202214632A (zh) * | 2020-07-27 | 2022-04-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 吲哚稠環類衍生物、其製備方法及其在醫藥上的應用 |
| CN114057759B (zh) * | 2020-08-07 | 2023-05-16 | 江苏恒瑞医药股份有限公司 | 稠合四环类衍生物、其制备方法及其在医药上的应用 |
| WO2022111636A1 (zh) | 2020-11-26 | 2022-06-02 | 江苏恒瑞医药股份有限公司 | 稠合三环化合物、其制备方法及其在医药上的应用 |
| WO2023025109A1 (zh) * | 2021-08-23 | 2023-03-02 | 上海维申医药有限公司 | 一类Toll样受体抑制剂及其制备和应用 |
| CN114656363A (zh) * | 2022-03-28 | 2022-06-24 | 南京林业大学 | 一种钯催化芳香酯类化合物的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011106276A1 (en) | 2010-02-25 | 2011-09-01 | Merck Sharp & Dohme Corp. | Task channel antagonists |
| US9428495B2 (en) * | 2013-10-14 | 2016-08-30 | Eisai R&D Management Co., Ltd. | Selectively substituted quinoline compounds |
| RS65319B1 (sr) * | 2015-12-17 | 2024-04-30 | Merck Patent Gmbh | 8-cijano-5-piperidino-hinolini kao tlr7/8 antagonisti i njihova upotreba u lečenju imunoloških poremećaja |
| EP4198031A1 (en) * | 2016-08-08 | 2023-06-21 | Merck Patent GmbH | Tlr7/8 antagonists and uses thereof |
-
2019
- 2019-06-03 EP EP19729220.4A patent/EP3802539B1/en active Active
- 2019-06-03 PE PE2020001875A patent/PE20210131A1/es unknown
- 2019-06-03 CN CN201980035182.7A patent/CN112204028B/zh active Active
- 2019-06-03 KR KR1020207034855A patent/KR20210018818A/ko unknown
- 2019-06-03 SG SG11202011137SA patent/SG11202011137SA/en unknown
- 2019-06-03 BR BR112020024782-0A patent/BR112020024782A2/pt not_active Application Discontinuation
- 2019-06-03 CR CR20200584A patent/CR20200584A/es unknown
- 2019-06-03 MX MX2020012827A patent/MX2020012827A/es unknown
- 2019-06-03 MA MA052747A patent/MA52747A/fr unknown
- 2019-06-03 JP JP2020567772A patent/JP7374130B2/ja active Active
- 2019-06-03 AU AU2019280728A patent/AU2019280728A1/en not_active Abandoned
- 2019-06-03 CA CA3098291A patent/CA3098291A1/en active Pending
- 2019-06-03 US US16/972,556 patent/US20210371432A1/en active Pending
- 2019-06-03 WO PCT/EP2019/064323 patent/WO2019233941A1/en unknown
- 2019-06-04 TW TW108119369A patent/TW202016111A/zh unknown
-
2020
- 2020-11-25 CL CL2020003065A patent/CL2020003065A1/es unknown
- 2020-11-26 CO CONC2020/0014677A patent/CO2020014677A2/es unknown
- 2020-12-01 IL IL279144A patent/IL279144A/en unknown
- 2020-12-04 PH PH12020552092A patent/PH12020552092A1/en unknown
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