JPWO2020194306A5 - - Google Patents

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Publication number
JPWO2020194306A5
JPWO2020194306A5 JP2021557247A JP2021557247A JPWO2020194306A5 JP WO2020194306 A5 JPWO2020194306 A5 JP WO2020194306A5 JP 2021557247 A JP2021557247 A JP 2021557247A JP 2021557247 A JP2021557247 A JP 2021557247A JP WO2020194306 A5 JPWO2020194306 A5 JP WO2020194306A5
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JP
Japan
Prior art keywords
nucleic acid
optionally
acid molecule
domain
transmembrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021557247A
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English (en)
Japanese (ja)
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JP2022527162A5 (https=
JP2022527162A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/IL2020/050360 external-priority patent/WO2020194306A1/en
Publication of JP2022527162A publication Critical patent/JP2022527162A/ja
Publication of JP2022527162A5 publication Critical patent/JP2022527162A5/ja
Publication of JPWO2020194306A5 publication Critical patent/JPWO2020194306A5/ja
Pending legal-status Critical Current

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JP2021557247A 2019-03-26 2020-03-26 Carを発現する遺伝的にリプログラミングされたtreg Pending JP2022527162A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962823711P 2019-03-26 2019-03-26
US62/823,711 2019-03-26
US201962898471P 2019-09-10 2019-09-10
US62/898,471 2019-09-10
PCT/IL2020/050360 WO2020194306A1 (en) 2019-03-26 2020-03-26 Genetically reprogrammed tregs expressing cars

Publications (3)

Publication Number Publication Date
JP2022527162A JP2022527162A (ja) 2022-05-31
JP2022527162A5 JP2022527162A5 (https=) 2023-04-03
JPWO2020194306A5 true JPWO2020194306A5 (https=) 2023-04-03

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ID=72610330

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557247A Pending JP2022527162A (ja) 2019-03-26 2020-03-26 Carを発現する遺伝的にリプログラミングされたtreg

Country Status (9)

Country Link
US (1) US20220186232A1 (https=)
EP (1) EP3947690A4 (https=)
JP (1) JP2022527162A (https=)
KR (1) KR20210143856A (https=)
CN (1) CN114127297A (https=)
AU (1) AU2020245329A1 (https=)
CA (1) CA3134878A1 (https=)
IL (1) IL286644A (https=)
WO (1) WO2020194306A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210277354A1 (en) * 2018-06-19 2021-09-09 Fondazione Telethon Production of engineered dendritic cells and uses thereof
WO2022169870A1 (en) * 2021-02-02 2022-08-11 Carisma Therapeutics Inc. Self-polarizing immune cells
JP2024546641A (ja) * 2021-12-09 2024-12-26 カリスマ セラピューティクス インコーポレイテッド 免疫細胞へのインビボ送達
TW202334400A (zh) * 2021-12-30 2023-09-01 美商Tr1X股份有限公司 表現il-10及嵌合抗原受體之cd4+ t細胞及其用途
CN117402257B (zh) * 2023-09-13 2025-08-26 武汉大学 人工病毒受体及其应用
WO2025148750A1 (zh) * 2024-01-08 2025-07-17 上药生物治疗(香港)有限公司 膜表达il-10及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596769A (en) * 1984-03-05 1986-06-24 Temple University Monoclonal antibodies to peptidoglycan and methods of preparing same
AU5275100A (en) * 1999-05-21 2000-12-12 Regents Of The University Of California, The Fluorescent protein indicators
WO2001089286A2 (en) * 2000-05-24 2001-11-29 Cel-Sci Corporation T cell binding ligand peptides, peptide constructs containing same and use thereof for treatment of immunological disorders
AU2003241127A1 (en) * 2002-06-12 2003-12-31 Gavish-Galilee Bio Applications Ltd MEMBRANE-ANCHORED Beta2 MICROGLOBULIN COVALENTLY LINKED TO MHC CLASS I PEPTIDE EPITOPES
JP5830744B2 (ja) * 2009-08-19 2015-12-09 国立大学法人東京工業大学 乳酸菌の付着性を誘導するペプチド及びその用途
EP2934532B1 (en) * 2012-12-20 2019-10-23 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
GB201317929D0 (en) * 2013-10-10 2013-11-27 Ucl Business Plc Chimeric antigen receptor
EP3202792B1 (en) * 2015-08-07 2024-08-14 Shenzhen In Vivo Biomedicine Technology Limited Company Chimeric antigen receptor containing intracellular domain of toll-like receptor
WO2017058752A1 (en) * 2015-09-28 2017-04-06 Trustees Of Dartmouth College Chimeric antigen receptor anti-inflammatory cells and methods of use
WO2017180993A1 (en) * 2016-04-14 2017-10-19 Bluebird Bio, Inc. Salvage chimeric antigen receptor systems
MX2019003462A (es) * 2016-09-28 2019-08-16 Gavish Galilee Bio Appl Ltd Una plataforma universal para el tratamiento con car que se dirige a una novedosa firma antigenica del cancer.
SG11202001011XA (en) * 2017-08-23 2020-03-30 Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft Chimeric antigen receptor and car-t cells that bind cxcr5
EP3768699B1 (en) * 2018-03-23 2025-11-12 Gavish-Galilee Bio Applications Ltd. Genetically reprogrammed tregs expressing membrane-bound il-10

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