JPWO2020194306A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020194306A5 JPWO2020194306A5 JP2021557247A JP2021557247A JPWO2020194306A5 JP WO2020194306 A5 JPWO2020194306 A5 JP WO2020194306A5 JP 2021557247 A JP2021557247 A JP 2021557247A JP 2021557247 A JP2021557247 A JP 2021557247A JP WO2020194306 A5 JPWO2020194306 A5 JP WO2020194306A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- optionally
- acid molecule
- domain
- transmembrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962823711P | 2019-03-26 | 2019-03-26 | |
| US62/823,711 | 2019-03-26 | ||
| US201962898471P | 2019-09-10 | 2019-09-10 | |
| US62/898,471 | 2019-09-10 | ||
| PCT/IL2020/050360 WO2020194306A1 (en) | 2019-03-26 | 2020-03-26 | Genetically reprogrammed tregs expressing cars |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022527162A JP2022527162A (ja) | 2022-05-31 |
| JP2022527162A5 JP2022527162A5 (https=) | 2023-04-03 |
| JPWO2020194306A5 true JPWO2020194306A5 (https=) | 2023-04-03 |
Family
ID=72610330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021557247A Pending JP2022527162A (ja) | 2019-03-26 | 2020-03-26 | Carを発現する遺伝的にリプログラミングされたtreg |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220186232A1 (https=) |
| EP (1) | EP3947690A4 (https=) |
| JP (1) | JP2022527162A (https=) |
| KR (1) | KR20210143856A (https=) |
| CN (1) | CN114127297A (https=) |
| AU (1) | AU2020245329A1 (https=) |
| CA (1) | CA3134878A1 (https=) |
| IL (1) | IL286644A (https=) |
| WO (1) | WO2020194306A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210277354A1 (en) * | 2018-06-19 | 2021-09-09 | Fondazione Telethon | Production of engineered dendritic cells and uses thereof |
| WO2022169870A1 (en) * | 2021-02-02 | 2022-08-11 | Carisma Therapeutics Inc. | Self-polarizing immune cells |
| JP2024546641A (ja) * | 2021-12-09 | 2024-12-26 | カリスマ セラピューティクス インコーポレイテッド | 免疫細胞へのインビボ送達 |
| TW202334400A (zh) * | 2021-12-30 | 2023-09-01 | 美商Tr1X股份有限公司 | 表現il-10及嵌合抗原受體之cd4+ t細胞及其用途 |
| CN117402257B (zh) * | 2023-09-13 | 2025-08-26 | 武汉大学 | 人工病毒受体及其应用 |
| WO2025148750A1 (zh) * | 2024-01-08 | 2025-07-17 | 上药生物治疗(香港)有限公司 | 膜表达il-10及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4596769A (en) * | 1984-03-05 | 1986-06-24 | Temple University | Monoclonal antibodies to peptidoglycan and methods of preparing same |
| AU5275100A (en) * | 1999-05-21 | 2000-12-12 | Regents Of The University Of California, The | Fluorescent protein indicators |
| WO2001089286A2 (en) * | 2000-05-24 | 2001-11-29 | Cel-Sci Corporation | T cell binding ligand peptides, peptide constructs containing same and use thereof for treatment of immunological disorders |
| AU2003241127A1 (en) * | 2002-06-12 | 2003-12-31 | Gavish-Galilee Bio Applications Ltd | MEMBRANE-ANCHORED Beta2 MICROGLOBULIN COVALENTLY LINKED TO MHC CLASS I PEPTIDE EPITOPES |
| JP5830744B2 (ja) * | 2009-08-19 | 2015-12-09 | 国立大学法人東京工業大学 | 乳酸菌の付着性を誘導するペプチド及びその用途 |
| EP2934532B1 (en) * | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| GB201317929D0 (en) * | 2013-10-10 | 2013-11-27 | Ucl Business Plc | Chimeric antigen receptor |
| EP3202792B1 (en) * | 2015-08-07 | 2024-08-14 | Shenzhen In Vivo Biomedicine Technology Limited Company | Chimeric antigen receptor containing intracellular domain of toll-like receptor |
| WO2017058752A1 (en) * | 2015-09-28 | 2017-04-06 | Trustees Of Dartmouth College | Chimeric antigen receptor anti-inflammatory cells and methods of use |
| WO2017180993A1 (en) * | 2016-04-14 | 2017-10-19 | Bluebird Bio, Inc. | Salvage chimeric antigen receptor systems |
| MX2019003462A (es) * | 2016-09-28 | 2019-08-16 | Gavish Galilee Bio Appl Ltd | Una plataforma universal para el tratamiento con car que se dirige a una novedosa firma antigenica del cancer. |
| SG11202001011XA (en) * | 2017-08-23 | 2020-03-30 | Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft | Chimeric antigen receptor and car-t cells that bind cxcr5 |
| EP3768699B1 (en) * | 2018-03-23 | 2025-11-12 | Gavish-Galilee Bio Applications Ltd. | Genetically reprogrammed tregs expressing membrane-bound il-10 |
-
2020
- 2020-03-26 US US17/598,208 patent/US20220186232A1/en active Pending
- 2020-03-26 WO PCT/IL2020/050360 patent/WO2020194306A1/en not_active Ceased
- 2020-03-26 KR KR1020217034307A patent/KR20210143856A/ko not_active Ceased
- 2020-03-26 CN CN202080038509.9A patent/CN114127297A/zh active Pending
- 2020-03-26 CA CA3134878A patent/CA3134878A1/en active Pending
- 2020-03-26 AU AU2020245329A patent/AU2020245329A1/en not_active Abandoned
- 2020-03-26 EP EP20778842.3A patent/EP3947690A4/en active Pending
- 2020-03-26 JP JP2021557247A patent/JP2022527162A/ja active Pending
-
2021
- 2021-09-23 IL IL286644A patent/IL286644A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Dal Porto et al. | A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations. | |
| Boyington et al. | Structure of killer cell immunoglobulin‐like receptors and their recognition of the class I MHC molecules | |
| Rodgers et al. | MHC class Ib molecules bridge innate and acquired immunity | |
| Michaëlsson et al. | Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers | |
| Salter et al. | A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2 | |
| Bléry et al. | Early signaling via inhibitory and activating NK receptors | |
| JP2025138715A5 (https=) | ||
| JP2018525006A5 (https=) | ||
| Straub et al. | Chicken NK cell receptors | |
| RU2018109426A (ru) | Химерные антигенные рецепторы со встроенными контролируемыми функциями | |
| RU2017133637A (ru) | Иммуномодулирующие слитые белки и пути их применения | |
| CN110291111A (zh) | 重组pMHC II类分子 | |
| JP2021519107A5 (https=) | ||
| KR20170002366A (ko) | 신속하고 포괄적인 t-세포 면역 모니터링을 위한 세포 플랫폼 | |
| RU2020109577A (ru) | Клетка | |
| JP2008500527A (ja) | 所定のpMHC複合体に結合するポリペプチドの同定法 | |
| Joyce et al. | The structural basis of ligand recognition by natural killer cell receptors | |
| Pettigrew et al. | Indirect T cell allorecognition and alloantibody-mediated rejection of MHC class I-disparate heart grafts | |
| JPWO2020194306A5 (https=) | ||
| US20220064256A1 (en) | Cd22-specific t cell receptors and adoptive t cell therapy for treatment of b cell malignancies | |
| EP1404362B1 (en) | Signal-1/signal-2 bifunctional peptide inhibitors | |
| CA2634292A1 (en) | Apoptosis-inducing protein complexes and therapeutic use thereof | |
| JPWO2020245343A5 (https=) | ||
| Stroynowski et al. | Novel molecules related to MHC antigens | |
| JPWO2019180724A5 (https=) |