JP2022527162A5 - - Google Patents

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Publication number
JP2022527162A5
JP2022527162A5 JP2021557247A JP2021557247A JP2022527162A5 JP 2022527162 A5 JP2022527162 A5 JP 2022527162A5 JP 2021557247 A JP2021557247 A JP 2021557247A JP 2021557247 A JP2021557247 A JP 2021557247A JP 2022527162 A5 JP2022527162 A5 JP 2022527162A5
Authority
JP
Japan
Prior art keywords
nucleic acid
acid molecule
optionally
domain
transmembrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021557247A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022527162A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IL2020/050360 external-priority patent/WO2020194306A1/en
Publication of JP2022527162A publication Critical patent/JP2022527162A/ja
Publication of JP2022527162A5 publication Critical patent/JP2022527162A5/ja
Pending legal-status Critical Current

Links

JP2021557247A 2019-03-26 2020-03-26 Carを発現する遺伝的にリプログラミングされたtreg Pending JP2022527162A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962823711P 2019-03-26 2019-03-26
US62/823,711 2019-03-26
US201962898471P 2019-09-10 2019-09-10
US62/898,471 2019-09-10
PCT/IL2020/050360 WO2020194306A1 (en) 2019-03-26 2020-03-26 Genetically reprogrammed tregs expressing cars

Publications (2)

Publication Number Publication Date
JP2022527162A JP2022527162A (ja) 2022-05-31
JP2022527162A5 true JP2022527162A5 (https=) 2023-04-03

Family

ID=72610330

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557247A Pending JP2022527162A (ja) 2019-03-26 2020-03-26 Carを発現する遺伝的にリプログラミングされたtreg

Country Status (9)

Country Link
US (1) US20220186232A1 (https=)
EP (1) EP3947690A4 (https=)
JP (1) JP2022527162A (https=)
KR (1) KR20210143856A (https=)
CN (1) CN114127297A (https=)
AU (1) AU2020245329A1 (https=)
CA (1) CA3134878A1 (https=)
IL (1) IL286644A (https=)
WO (1) WO2020194306A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019291069B2 (en) * 2018-06-19 2026-02-19 Fondazione Centro San Raffaele Production of engineered dendritic cells and uses thereof
EP4288072A4 (en) * 2021-02-02 2025-10-08 Carisma Therapeutics Inc SELF-POLARIZING IMMUNE CELLS
EP4444361A4 (en) * 2021-12-09 2025-12-10 Carisma Therapeutics Inc IN VIVO ADMINISTRATION TO IMMUNE CELLS
WO2023129929A1 (en) * 2021-12-30 2023-07-06 Tr1X, Inc. Cd4+ t cells expressing il-10 and chimeric antigen receptors and uses thereof
CN117402257B (zh) * 2023-09-13 2025-08-26 武汉大学 人工病毒受体及其应用
WO2025148750A1 (zh) * 2024-01-08 2025-07-17 上药生物治疗(香港)有限公司 膜表达il-10及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596769A (en) * 1984-03-05 1986-06-24 Temple University Monoclonal antibodies to peptidoglycan and methods of preparing same
AU5275100A (en) * 1999-05-21 2000-12-12 Regents Of The University Of California, The Fluorescent protein indicators
AU2001264902A1 (en) * 2000-05-24 2001-12-03 Cel-Sci Corporation T cell binding ligand peptides, peptide constructs containing same and use thereof for treatment of immunological disorders
ATE509025T1 (de) * 2002-06-12 2011-05-15 Gavish Galilee Bio Appl Ltd ßMIT MHC-KLASSE-I-PEPTIDEPITOPEN KOVALENT VERKN PFTES MEMBRANVERANKERTES BETA2-MIKROGLOBULINß
JP5830744B2 (ja) * 2009-08-19 2015-12-09 国立大学法人東京工業大学 乳酸菌の付着性を誘導するペプチド及びその用途
EP4282419A1 (en) * 2012-12-20 2023-11-29 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
GB201317929D0 (en) * 2013-10-10 2013-11-27 Ucl Business Plc Chimeric antigen receptor
US10093717B2 (en) * 2015-08-07 2018-10-09 Shenzhen In Vivo Biomedicine Technology Limited Company Chimeric antigen receptor containing a toll-like receptor intracellular domain
US11365391B2 (en) * 2015-09-28 2022-06-21 Trustees Of Dartmouth College Chimeric antigen receptor anti-inflammatory cells and methods of use
EP3443002A4 (en) * 2016-04-14 2019-12-04 Bluebird Bio, Inc. SYSTEMS FOR RECOVERED CHIMERIC ANTIGEN RECEPTORS
BR112019006006A2 (pt) * 2016-09-28 2019-06-25 Gavish-Galilee Bio Applications Ltd. molécula de ácido nucleico, vetor, métodos para preparação de um receptor de antígeno quimérico inibidor, para preparar uma célula imune efetora segura, para selecionar um biomarcador personalizado e para tratar o câncer em um paciente com um tumor, célula imune efetora segura, e, combinação de duas ou mais moléculas de ácido nucleico.
SG11202001011XA (en) * 2017-08-23 2020-03-30 Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft Chimeric antigen receptor and car-t cells that bind cxcr5
AU2019240370B2 (en) * 2018-03-23 2024-03-07 Gavish-Galilee Bio Applications Ltd. Genetically reprogrammed Tregs expressing membrane-bound IL-10

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