JP2021520820A5 - - Google Patents

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Publication number
JP2021520820A5
JP2021520820A5 JP2020556239A JP2020556239A JP2021520820A5 JP 2021520820 A5 JP2021520820 A5 JP 2021520820A5 JP 2020556239 A JP2020556239 A JP 2020556239A JP 2020556239 A JP2020556239 A JP 2020556239A JP 2021520820 A5 JP2021520820 A5 JP 2021520820A5
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JP
Japan
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sequence
domain
seq
car according
human
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JP2020556239A
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English (en)
Japanese (ja)
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JPWO2019197678A5 (https=
JP7447014B2 (ja
JP2021520820A (ja
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Priority claimed from PCT/EP2019/059590 external-priority patent/WO2019197678A1/en
Publication of JP2021520820A publication Critical patent/JP2021520820A/ja
Publication of JPWO2019197678A5 publication Critical patent/JPWO2019197678A5/ja
Publication of JP2021520820A5 publication Critical patent/JP2021520820A5/ja
Priority to JP2024028368A priority Critical patent/JP2024051109A/ja
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JP2020556239A 2018-04-13 2019-04-15 インターロイキン23受容体に特異的なキメラ抗原受容体 Active JP7447014B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024028368A JP2024051109A (ja) 2018-04-13 2024-02-28 インターロイキン23受容体に特異的なキメラ抗原受容体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862657233P 2018-04-13 2018-04-13
US62/657,233 2018-04-13
PCT/EP2019/059590 WO2019197678A1 (en) 2018-04-13 2019-04-15 Chimeric antigen receptor specific for interleukin-23 receptor

Related Child Applications (1)

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JP2024028368A Division JP2024051109A (ja) 2018-04-13 2024-02-28 インターロイキン23受容体に特異的なキメラ抗原受容体

Publications (4)

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JP2021520820A JP2021520820A (ja) 2021-08-26
JPWO2019197678A5 JPWO2019197678A5 (https=) 2022-04-26
JP2021520820A5 true JP2021520820A5 (https=) 2022-04-26
JP7447014B2 JP7447014B2 (ja) 2024-03-11

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JP2020556239A Active JP7447014B2 (ja) 2018-04-13 2019-04-15 インターロイキン23受容体に特異的なキメラ抗原受容体
JP2024028368A Pending JP2024051109A (ja) 2018-04-13 2024-02-28 インターロイキン23受容体に特異的なキメラ抗原受容体

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Country Status (12)

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US (2) US11981739B2 (https=)
EP (1) EP3774907A1 (https=)
JP (2) JP7447014B2 (https=)
KR (1) KR102856271B1 (https=)
CN (1) CN112292400A (https=)
AU (2) AU2019250692A1 (https=)
BR (1) BR112020020919A2 (https=)
CA (1) CA3096500A1 (https=)
IL (1) IL277946A (https=)
MX (1) MX2020010808A (https=)
SG (1) SG11202010116PA (https=)
WO (1) WO2019197678A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202010116PA (en) * 2018-04-13 2020-11-27 Sangamo Therapeutics France Chimeric antigen receptor specific for interleukin-23 receptor
US20220281943A1 (en) * 2019-08-14 2022-09-08 The Regents Of The University Of California Car-t cells specific for modified proteins in extracellular spaces
EP3808766A1 (en) * 2019-10-15 2021-04-21 Sangamo Therapeutics France Chimeric antigen receptor specific for interleukin-23 receptor
CN115335407B (zh) * 2020-03-25 2024-08-27 北京艺妙神州医药科技有限公司 结合cd19的嵌合抗原受体及其用途
GB202007842D0 (en) * 2020-05-26 2020-07-08 Quell Therapeutics Ltd Polypeptide useful in adoptive cell therapy
CN114907485B (zh) * 2021-02-08 2024-04-26 浙江大学 一种以内源性蛋白质分子替代单结构域抗体的嵌合抗原受体
KR20240025524A (ko) * 2021-06-25 2024-02-27 상가모 테라퓨틱스, 인코포레이티드 Il-23r에 특이적인 항원 결합제 및 이의 용도
WO2024215677A2 (en) * 2023-04-14 2024-10-17 Rutgers, The State University Of New Jersey Compositions and methods for targeting solid tumors with chimeric antigen receptor (car) macrophages
WO2025014884A2 (en) * 2023-07-10 2025-01-16 The Board Of Trustees Of The Leland Stanford Junior University Synthetic bi-functional degraders of integrins
JP2025150298A (ja) 2024-03-27 2025-10-09 エスペック株式会社 降雨試験装置及び降雨試験方法

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US6352694B1 (en) 1994-06-03 2002-03-05 Genetics Institute, Inc. Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
US5858358A (en) 1992-04-07 1999-01-12 The United States Of America As Represented By The Secretary Of The Navy Methods for selectively stimulating proliferation of T cells
US6905680B2 (en) 1988-11-23 2005-06-14 Genetics Institute, Inc. Methods of treating HIV infected subjects
US6534055B1 (en) 1988-11-23 2003-03-18 Genetics Institute, Inc. Methods for selectively stimulating proliferation of T cells
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
DE69232137T2 (de) 1991-11-25 2002-05-29 Enzon Inc Multivalente antigen-bindende proteine
US5350674A (en) 1992-09-04 1994-09-27 Becton, Dickinson And Company Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
US7175843B2 (en) 1994-06-03 2007-02-13 Genetics Institute, Llc Methods for selectively stimulating proliferation of T cells
US7067318B2 (en) 1995-06-07 2006-06-27 The Regents Of The University Of Michigan Methods for transfecting T cells
US6692964B1 (en) 1995-05-04 2004-02-17 The United States Of America As Represented By The Secretary Of The Navy Methods for transfecting T cells
EP1958962A3 (en) 1997-06-12 2013-05-01 Novartis International Pharmaceutical Ltd. Artificial antibody polypeptides
CA2386270A1 (en) 1999-10-15 2001-04-26 University Of Massachusetts Rna interference pathway genes as tools for targeted genetic interference
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
CA2406864A1 (en) 2000-02-24 2001-08-30 Life Technologies Corporation Simultaneous stimulation and concentration of cells
US6867041B2 (en) 2000-02-24 2005-03-15 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
US7572631B2 (en) 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
US6797514B2 (en) 2000-02-24 2004-09-28 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
AU2001275474A1 (en) 2000-06-12 2001-12-24 Akkadix Corporation Materials and methods for the control of nematodes
US7745140B2 (en) 2002-01-03 2010-06-29 The Trustees Of The University Of Pennsylvania Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
WO2004094642A2 (en) 2003-04-24 2004-11-04 Fondazione Centro San Raffaele Del Monte Tabor Lentiviral vectors carrying synthetic bi-directional promoters and uses thereof
AU2005250408B2 (en) 2004-05-27 2010-09-23 The Trustees Of The University Of Pennsylvania Novel artificial antigen presenting cells and uses therefor
US20070036773A1 (en) 2005-08-09 2007-02-15 City Of Hope Generation and application of universal T cells for B-ALL
GB0603081D0 (en) 2006-02-15 2006-03-29 Dynal Biotech Asa Oslo Method
EP2126054B1 (en) * 2007-01-31 2016-07-06 Yeda Research And Development Company Limited Redirected, genetically-engineered t regulatory cells and their use in suppression of autoimmune and inflammatory disease
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US8956828B2 (en) 2009-11-10 2015-02-17 Sangamo Biosciences, Inc. Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
CA2993567C (en) 2010-07-21 2022-06-28 Sangamo Biosciences, Inc. Methods and compositions for modification of a t-cell receptor gene
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
EP2694549B1 (en) 2011-04-08 2018-08-15 The United States of America, as represented by The Secretary, Department of Health and Human Services Anti-epidermal growth factor receptor variant iii chimeric antigen receptors and use of same for the treatment of cancer
WO2013059593A1 (en) 2011-10-20 2013-04-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-cd22 chimeric antigen receptors
GB201206559D0 (en) 2012-04-13 2012-05-30 Ucl Business Plc Polypeptide
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
AU2013359262C1 (en) 2012-12-12 2021-05-13 Massachusetts Institute Of Technology CRISPR-Cas component systems, methods and compositions for sequence manipulation
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
CA2894684A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Engineering and optimization of improved crispr-cas systems, methods and enzyme compositions for sequence manipulation in eukaryotes
EP3415534A1 (en) * 2013-05-10 2018-12-19 Numab Therapeutics AG Bispecific constructs and their use in the treatment of various diseases
JP2017521998A (ja) * 2014-05-12 2017-08-10 ヌマブ アクチェンゲゼルシャフト 新規多重特異性分子及びかかる多重特異性分子に基づく新規治療方法
MX2017001229A (es) * 2014-07-29 2017-05-01 Pfizer Receptores de antigenos quimericos especificos de egfrviii para inmunoterapia de cancer.
JP2017531430A (ja) 2014-10-07 2017-10-26 セレクティスCellectis Carによって誘導される免疫細胞の活性を調節するための方法
ES2869972T3 (es) 2015-01-26 2021-10-26 Cellectis Sistemas de receptores de antígenos quiméricos dirigidos por mAb para clasificar/agotar células inmunitarias genomanipuladas
EP3298041A1 (en) 2015-05-18 2018-03-28 Numab Therapeutics AG Novel treatment methods based on multifunctional molecules
IL261713B2 (en) * 2016-03-19 2023-09-01 F1 Oncology Inc Methods and preparations for the transfer of lymphocytes and their regulated expansion
MY210545A (en) * 2016-04-01 2025-09-30 Kite Pharma Inc Chimeric receptors to flt3 and methods of use thereof
WO2017210749A1 (en) * 2016-06-10 2017-12-14 Adelaide Research & Innovation Pty Ltd Methods and products for treating autoimmune diseases
GB201610512D0 (en) 2016-06-16 2016-08-03 Autolus Ltd Chimeric antigen receptor
EP3263595A1 (en) 2016-06-30 2018-01-03 Medizinische Hochschule Hannover Fusion protein for use in the treatment of hvg disease
CA3000514A1 (en) 2016-08-04 2018-02-08 Memorial Sloan-Kettering Cancer Center Cancer antigen targets and uses thereof
ES2967739T3 (es) 2017-06-05 2024-05-03 Numab Therapeutics AG Formato de anticuerpo heterodimérico multiespecífico dirigido al menos a CD3 y a HSA
CA3076261A1 (en) * 2017-09-19 2019-03-28 Admare Vintageco1 Investments Ltd. Anti-hla-a2 antibodies and methods of using the same
SG11202010116PA (en) * 2018-04-13 2020-11-27 Sangamo Therapeutics France Chimeric antigen receptor specific for interleukin-23 receptor

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