JP2022543742A5 - - Google Patents
Info
- Publication number
- JP2022543742A5 JP2022543742A5 JP2022503794A JP2022503794A JP2022543742A5 JP 2022543742 A5 JP2022543742 A5 JP 2022543742A5 JP 2022503794 A JP2022503794 A JP 2022503794A JP 2022503794 A JP2022503794 A JP 2022503794A JP 2022543742 A5 JP2022543742 A5 JP 2022543742A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- item
- antigen
- promoter
- fusion polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024198293A JP2025015619A (ja) | 2019-07-19 | 2024-11-13 | 免疫療法のための融合ポリペプチド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962876338P | 2019-07-19 | 2019-07-19 | |
| US62/876,338 | 2019-07-19 | ||
| PCT/US2020/042753 WO2021016174A1 (en) | 2019-07-19 | 2020-07-20 | Fusion polypeptide for immunotherapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024198293A Division JP2025015619A (ja) | 2019-07-19 | 2024-11-13 | 免疫療法のための融合ポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022543742A JP2022543742A (ja) | 2022-10-14 |
| JP2022543742A5 true JP2022543742A5 (https=) | 2023-07-28 |
| JP7676358B2 JP7676358B2 (ja) | 2025-05-14 |
Family
ID=74192452
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503794A Active JP7676358B2 (ja) | 2019-07-19 | 2020-07-20 | 免疫療法のための融合ポリペプチド |
| JP2024198293A Pending JP2025015619A (ja) | 2019-07-19 | 2024-11-13 | 免疫療法のための融合ポリペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024198293A Pending JP2025015619A (ja) | 2019-07-19 | 2024-11-13 | 免疫療法のための融合ポリペプチド |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220133802A1 (https=) |
| EP (1) | EP3999079A4 (https=) |
| JP (2) | JP7676358B2 (https=) |
| KR (1) | KR20220035471A (https=) |
| CN (1) | CN115298208A (https=) |
| AU (1) | AU2020315796A1 (https=) |
| BR (1) | BR112022000976A2 (https=) |
| CA (1) | CA3148072A1 (https=) |
| IL (1) | IL289887A (https=) |
| MX (1) | MX2022000769A (https=) |
| WO (1) | WO2021016174A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4277639A4 (en) * | 2021-01-15 | 2025-03-05 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | HYBRID AND TRUNCATED IMMUNE CELL PROTEINS |
| IL305795A (en) * | 2021-03-10 | 2023-11-01 | B G Negev Technologies & Applications Ltd At Ben Gurion Univ | Reporter cells expressing chimeric proteins for use in determining the presence and or activity of immune barrier molecules |
| US12486310B2 (en) | 2021-04-21 | 2025-12-02 | Brigham Young University | Metastasis inhibiting protein |
| WO2022233956A1 (en) | 2021-05-05 | 2022-11-10 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding prame |
| WO2023020471A1 (en) * | 2021-08-16 | 2023-02-23 | Utc Therapeutics (Shanghai) Co., Ltd. | Cd123-targetting antibodies and uses thereof in cancer therapies |
| WO2023081542A1 (en) * | 2021-11-02 | 2023-05-11 | Christopher Mendoza | Metastasis inhibiting protein |
| JP2025501272A (ja) | 2021-12-28 | 2025-01-17 | ムネモ・セラピューティクス | 不活性化されたsuv39h1及び改変tcrを有する免疫細胞 |
| WO2023139269A1 (en) | 2022-01-21 | 2023-07-27 | Mnemo Therapeutics | Modulation of suv39h1 expression by rnas |
| EP4279085A1 (en) | 2022-05-20 | 2023-11-22 | Mnemo Therapeutics | Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease |
| WO2024062138A1 (en) | 2022-09-23 | 2024-03-28 | Mnemo Therapeutics | Immune cells comprising a modified suv39h1 gene |
| JP2025536892A (ja) * | 2022-10-21 | 2025-11-12 | メモリアル スローン ケタリング キャンサー センター | 抗cd70キメラ受容体を発現する細胞及びその用途 |
| EP4605436A2 (en) * | 2022-10-21 | 2025-08-27 | Memorial Sloan-Kettering Cancer Center | Cells and compositions for treating cancer |
| IL322949A (en) | 2023-03-03 | 2025-10-01 | Arsenal Biosciences Inc | Systems targeting PSMA and CA9 |
| WO2024227145A1 (en) * | 2023-04-27 | 2024-10-31 | Memorial Sloan-Kettering Cancer Center | Enhanced fusion polypeptide for immunotherapy |
| WO2026078056A1 (en) * | 2024-10-09 | 2026-04-16 | Leibniz-Institut Für Immuntherapie (Lit) | Engineered tnfr ligands |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1975A (en) | 1841-02-12 | Manner of constructing corn-shellers | ||
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| JPS6412935A (en) | 1987-07-02 | 1989-01-17 | Mitsubishi Electric Corp | Constant-speed travel device for vehicle |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| AU2002221780A1 (en) * | 2000-10-31 | 2002-05-15 | F.Hoffmann-La Roche Ag | Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof |
| US7446190B2 (en) | 2002-05-28 | 2008-11-04 | Sloan-Kettering Institute For Cancer Research | Nucleic acids encoding chimeric T cell receptors |
| GB0620934D0 (en) * | 2006-10-20 | 2006-11-29 | Cambridge Antibody Tech | Protein variants |
| SI2856876T1 (en) * | 2007-03-30 | 2018-04-30 | Memorial Sloan-Kettering Cancer Center | Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes |
| JP2012500855A (ja) * | 2008-08-25 | 2012-01-12 | アンプリミューン、インコーポレーテッド | Pd−1アンタゴニストおよび感染性疾患を処置するための方法 |
| EP4406604A3 (en) * | 2015-03-05 | 2024-10-23 | Fred Hutchinson Cancer Center | Immunomodulatory fusion proteins and uses thereof |
| PL3298033T5 (pl) * | 2015-05-18 | 2023-10-30 | TCR2 Therapeutics Inc. | Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych |
| DK3909972T5 (da) * | 2015-06-19 | 2024-08-05 | Sebastian Kobold | Pd1-cd28-fusionsproteiner og disses anvendelse i medicin |
| US11655452B2 (en) * | 2015-06-25 | 2023-05-23 | Icell Gene Therapeutics Inc. | Chimeric antigen receptors (CARs), compositions and methods of use thereof |
| CN106929523A (zh) * | 2015-12-29 | 2017-07-07 | 中国人民解放军第二军医大学 | 酵母表达重组hCD80-GPI融合蛋白的制备及其在抗肿瘤中的应用 |
| EP3433269B1 (en) * | 2016-03-23 | 2023-09-27 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Fusion proteins of pd-1 and 4-1bb |
| US20180186855A1 (en) * | 2016-03-23 | 2018-07-05 | Alector Llc | Chimeric receptors and methods of use thereof |
| EP3231813A1 (en) * | 2016-03-29 | 2017-10-18 | F. Hoffmann-La Roche AG | Trimeric costimulatory tnf family ligand-containing antigen binding molecules |
| WO2017181152A2 (en) * | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| MX2018012472A (es) * | 2016-04-15 | 2019-08-12 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras variantes de ligando icos y sus usos. |
| EP4628587A3 (en) | 2016-04-15 | 2026-02-25 | Memorial Sloan Kettering Cancer Center | Transgenic t cell and chimeric antigen receptor t cell compositions and related methods |
| BR112019006781A2 (pt) * | 2016-10-07 | 2019-07-30 | Novartis Ag | receptores de antígeno quiméricos para o tratamento de câncer |
| CN119409836A (zh) * | 2017-03-17 | 2025-02-11 | 弗雷德哈钦森癌症中心 | 免疫调节融合蛋白及其用途 |
| CN108866003A (zh) * | 2017-05-16 | 2018-11-23 | 科济生物医药(上海)有限公司 | 基因工程化的细胞及应用 |
| CA3287539A1 (en) * | 2017-06-21 | 2026-03-02 | Icell Gene Therapeutics Llc | CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF |
| US12053490B2 (en) * | 2017-10-26 | 2024-08-06 | St. Jude Children's Research Hospital, Inc. | Methods and compositions for treating CD33+ cancers and improving in vivo persistence of chimeric antigen receptor T cells |
| JP7416695B2 (ja) * | 2017-12-29 | 2024-01-17 | メモリアル スローン-ケタリング キャンサー センター | 増強されたキメラ抗原受容体およびその使用 |
-
2020
- 2020-07-20 AU AU2020315796A patent/AU2020315796A1/en active Pending
- 2020-07-20 WO PCT/US2020/042753 patent/WO2021016174A1/en not_active Ceased
- 2020-07-20 CA CA3148072A patent/CA3148072A1/en active Pending
- 2020-07-20 MX MX2022000769A patent/MX2022000769A/es unknown
- 2020-07-20 EP EP20843016.5A patent/EP3999079A4/en active Pending
- 2020-07-20 CN CN202080063644.9A patent/CN115298208A/zh active Pending
- 2020-07-20 BR BR112022000976A patent/BR112022000976A2/pt unknown
- 2020-07-20 JP JP2022503794A patent/JP7676358B2/ja active Active
- 2020-07-20 KR KR1020227005411A patent/KR20220035471A/ko not_active Withdrawn
-
2022
- 2022-01-16 IL IL289887A patent/IL289887A/en unknown
- 2022-01-19 US US17/578,989 patent/US20220133802A1/en active Pending
-
2024
- 2024-11-13 JP JP2024198293A patent/JP2025015619A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022543742A5 (https=) | ||
| CA2791383C (en) | Compositions and methods for targeted immunomodulatory antibodies and fusion proteins | |
| EP3606947B1 (en) | Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody | |
| RU2761377C2 (ru) | Иммуноконъюгаты антитела к pd-1 с мутантом il-2 или с il-15 | |
| JP2020525536A5 (https=) | ||
| JP2017537925A5 (https=) | ||
| JP2017537629A5 (https=) | ||
| AU2021383237A1 (en) | Nkg2a-targeting antibody and use thereof | |
| JP2025517479A (ja) | Bcma-cd19を標的とする二重特異性キメラ抗原受容体およびその用途 | |
| JP2024525492A5 (https=) | ||
| JP7812549B2 (ja) | 人工免疫監視キメラ抗原受容体(ai-car)及びそれを発現する細胞 | |
| JP2022513372A5 (https=) | ||
| US12311022B2 (en) | Bispecific chimeric antigen receptors targeting CD20 and BCMA | |
| KR20250170671A (ko) | Bcma 및 cd19를 표적화하는 이중특이적 키메라 항원 수용체 | |
| WO2020087116A1 (en) | Bispecific polypeptides for engagement of car expressing immune cells with antigen presenting cells and uses thereof | |
| JP2022548112A5 (https=) | ||
| CN115873802A (zh) | 嵌合抗原受体免疫细胞及其制法和应用 | |
| CN120476143A (zh) | 包含与il18组合的新型cd19结合剂的car-t构建体及其使用方法 | |
| CN114615992A (zh) | 表达t调节性细胞的抗cd83嵌合抗原受体 | |
| RU2022103913A (ru) | Слитый полипептид для иммунотерапии | |
| EP4566619A1 (en) | Targeting modules against cd19 and cd20 for use in a method for stimulating a reversed chimeric antigen receptor-mediated immune response in a mammal | |
| KR20190028343A (ko) | 뉴로필린 1 (Neuropilin 1, NRP1)에 특이적으로 결합하는 펩타이드를 포함하는 조절 T 세포의 활성을 억제하기 위한 조성물 | |
| AU2024393901A1 (en) | Targeting modules against cd19 and cd20 for use in a method for stimulating a reversed | |
| JP2026513997A (ja) | Bcma及びcd19を標的とする二重特異性キメラ抗原受容体 | |
| AU2023289687A1 (en) | Targeting modules against cd123 for use in a method for stimulating a chimeric antigen receptor-mediated immune response in a mammal |