KR20210143856A - CAR을 발현하는 유전적으로 리프로그래밍된 Treg - Google Patents

CAR을 발현하는 유전적으로 리프로그래밍된 Treg Download PDF

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KR20210143856A
KR20210143856A KR1020217034307A KR20217034307A KR20210143856A KR 20210143856 A KR20210143856 A KR 20210143856A KR 1020217034307 A KR1020217034307 A KR 1020217034307A KR 20217034307 A KR20217034307 A KR 20217034307A KR 20210143856 A KR20210143856 A KR 20210143856A
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기드온 그로스
하다스 와인스타인-마롬
사라 포즈너
아미트 크로너
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가비쉬-가릴리 바이오 어플리케이션스 리미티드.
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KR1020217034307A 2019-03-26 2020-03-26 CAR을 발현하는 유전적으로 리프로그래밍된 Treg Ceased KR20210143856A (ko)

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US201962823711P 2019-03-26 2019-03-26
US62/823,711 2019-03-26
US201962898471P 2019-09-10 2019-09-10
US62/898,471 2019-09-10
PCT/IL2020/050360 WO2020194306A1 (en) 2019-03-26 2020-03-26 Genetically reprogrammed tregs expressing cars

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US (1) US20220186232A1 (https=)
EP (1) EP3947690A4 (https=)
JP (1) JP2022527162A (https=)
KR (1) KR20210143856A (https=)
CN (1) CN114127297A (https=)
AU (1) AU2020245329A1 (https=)
CA (1) CA3134878A1 (https=)
IL (1) IL286644A (https=)
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US20210277354A1 (en) * 2018-06-19 2021-09-09 Fondazione Telethon Production of engineered dendritic cells and uses thereof
WO2022169870A1 (en) * 2021-02-02 2022-08-11 Carisma Therapeutics Inc. Self-polarizing immune cells
JP2024546641A (ja) * 2021-12-09 2024-12-26 カリスマ セラピューティクス インコーポレイテッド 免疫細胞へのインビボ送達
TW202334400A (zh) * 2021-12-30 2023-09-01 美商Ｔｒ１Ｘ股份有限公司 表現il-10及嵌合抗原受體之cd4+ t細胞及其用途
CN117402257B (zh) * 2023-09-13 2025-08-26 武汉大学 人工病毒受体及其应用
WO2025148750A1 (zh) * 2024-01-08 2025-07-17 上药生物治疗（香港）有限公司 膜表达il-10及其用途

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US4596769A (en) * 1984-03-05 1986-06-24 Temple University Monoclonal antibodies to peptidoglycan and methods of preparing same
AU5275100A (en) * 1999-05-21 2000-12-12 Regents Of The University Of California, The Fluorescent protein indicators
WO2001089286A2 (en) * 2000-05-24 2001-11-29 Cel-Sci Corporation T cell binding ligand peptides, peptide constructs containing same and use thereof for treatment of immunological disorders
AU2003241127A1 (en) * 2002-06-12 2003-12-31 Gavish-Galilee Bio Applications Ltd MEMBRANE-ANCHORED Beta2 MICROGLOBULIN COVALENTLY LINKED TO MHC CLASS I PEPTIDE EPITOPES
JP5830744B2 (ja) * 2009-08-19 2015-12-09 国立大学法人東京工業大学 乳酸菌の付着性を誘導するペプチド及びその用途
EP2934532B1 (en) * 2012-12-20 2019-10-23 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
GB201317929D0 (en) * 2013-10-10 2013-11-27 Ucl Business Plc Chimeric antigen receptor
EP3202792B1 (en) * 2015-08-07 2024-08-14 Shenzhen In Vivo Biomedicine Technology Limited Company Chimeric antigen receptor containing intracellular domain of toll-like receptor
WO2017058752A1 (en) * 2015-09-28 2017-04-06 Trustees Of Dartmouth College Chimeric antigen receptor anti-inflammatory cells and methods of use
WO2017180993A1 (en) * 2016-04-14 2017-10-19 Bluebird Bio, Inc. Salvage chimeric antigen receptor systems
MX2019003462A (es) * 2016-09-28 2019-08-16 Gavish Galilee Bio Appl Ltd Una plataforma universal para el tratamiento con car que se dirige a una novedosa firma antigenica del cancer.
SG11202001011XA (en) * 2017-08-23 2020-03-30 Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft Chimeric antigen receptor and car-t cells that bind cxcr5
EP3768699B1 (en) * 2018-03-23 2025-11-12 Gavish-Galilee Bio Applications Ltd. Genetically reprogrammed tregs expressing membrane-bound il-10

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EP3947690A4 (en) 2022-12-21
AU2020245329A1 (en) 2021-10-28
US20220186232A1 (en) 2022-06-16
EP3947690A1 (en) 2022-02-09
WO2020194306A1 (en) 2020-10-01
CA3134878A1 (en) 2020-10-01
IL286644A (en) 2021-10-31
JP2022527162A (ja) 2022-05-31

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