JPWO2020184479A1 - - Google Patents

Info

Publication number
JPWO2020184479A1
JPWO2020184479A1 JP2021505049A JP2021505049A JPWO2020184479A1 JP WO2020184479 A1 JPWO2020184479 A1 JP WO2020184479A1 JP 2021505049 A JP2021505049 A JP 2021505049A JP 2021505049 A JP2021505049 A JP 2021505049A JP WO2020184479 A1 JPWO2020184479 A1 JP WO2020184479A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021505049A
Other languages
Japanese (ja)
Other versions
JPWO2020184479A5 (enExample
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2020184479A1 publication Critical patent/JPWO2020184479A1/ja
Publication of JPWO2020184479A5 publication Critical patent/JPWO2020184479A5/ja
Priority to JP2024177773A priority Critical patent/JP2024180505A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021505049A 2019-03-08 2020-03-06 Pending JPWO2020184479A1 (enExample)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024177773A JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019043089 2019-03-08
JP2019071396 2019-04-03
PCT/JP2020/009847 WO2020184479A1 (ja) 2019-03-08 2020-03-06 刺激感が抑制された眼科組成物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024177773A Division JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Publications (2)

Publication Number Publication Date
JPWO2020184479A1 true JPWO2020184479A1 (enExample) 2020-09-17
JPWO2020184479A5 JPWO2020184479A5 (enExample) 2023-03-10

Family

ID=72427534

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021505049A Pending JPWO2020184479A1 (enExample) 2019-03-08 2020-03-06
JP2024177773A Pending JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024177773A Pending JP2024180505A (ja) 2019-03-08 2024-10-10 刺激感が抑制された眼科組成物

Country Status (4)

Country Link
JP (2) JPWO2020184479A1 (enExample)
CN (1) CN113423428A (enExample)
TW (1) TW202100144A (enExample)
WO (1) WO2020184479A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230350228A1 (en) 2022-04-28 2023-11-02 Coopervision International Limited Contact lens

Citations (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505909A (en) * 1980-09-17 1985-03-19 Bernstein Joel E Method and composition for treating and preventing irritation of the eyes
JPH07316060A (ja) * 1994-03-31 1995-12-05 Lion Corp 安定な点眼剤
JPH09132526A (ja) * 1995-11-09 1997-05-20 Lion Corp 点眼剤
JPH09169642A (ja) * 1995-12-18 1997-06-30 Lion Corp テトラヒドロゾリン含有液剤
JPH09309835A (ja) * 1996-05-21 1997-12-02 Lion Corp グリチルリチン酸アルキルエステル含有薬液
JP2000327573A (ja) * 1999-05-18 2000-11-28 Taisho Pharmaceut Co Ltd 粘膜適用組成物
JP2001302518A (ja) * 2000-02-15 2001-10-31 Rohto Pharmaceut Co Ltd 官能改善方法および官能改善剤
JP2003073303A (ja) * 2001-09-05 2003-03-12 Senju Pharmaceut Co Ltd 眼局所用液剤の清涼化作用の持続方法
JP2003146908A (ja) * 2001-11-12 2003-05-21 Rohto Pharmaceut Co Ltd 水性組成物
JP2003183157A (ja) * 2001-12-19 2003-07-03 Lion Corp 眼科用組成物
JP2004143156A (ja) * 2002-10-01 2004-05-20 Taisho Pharmaceut Co Ltd 点眼剤
JP2004175770A (ja) * 2002-11-29 2004-06-24 Rohto Pharmaceut Co Ltd ケトチフェン及びイミダゾリン化合物含有組成物
US20050271748A1 (en) * 2002-04-26 2005-12-08 Allergan, Inc. Compositions for treating hyperemia
JP2006176501A (ja) * 2004-11-26 2006-07-06 Taisho Pharmaceut Co Ltd 眼科用剤
JP2006312627A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有組成物
JP2006312628A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有水性組成物
WO2007108541A1 (ja) * 2006-03-23 2007-09-27 Senju Pharmaceutical Co., Ltd. キサンタンガムおよびブドウ糖を含有する眼科用組成物
JP2008024700A (ja) * 2006-06-23 2008-02-07 Rohto Pharmaceut Co Ltd ベルベリン含有水性組成物
JP2009029779A (ja) * 2007-06-29 2009-02-12 Rohto Pharmaceut Co Ltd レボカバスチン及び／又はその塩を含有する水性医薬組成物
JP2009096793A (ja) * 2007-06-01 2009-05-07 Rohto Pharmaceut Co Ltd プラノプロフェン含有水性医薬組成物
JP2011074092A (ja) * 2003-04-04 2011-04-14 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2011093897A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科用液体組成物
JP2011093898A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科組成物
JP2012144509A (ja) * 2011-01-12 2012-08-02 Saga Seiyaku Kk 多成分配合の点眼剤
JP2012206977A (ja) * 2011-03-29 2012-10-25 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2013189623A (ja) * 2012-01-30 2013-09-26 Symrise Ag 組成物
JP2013237638A (ja) * 2012-05-15 2013-11-28 Lion Corp 眼科組成物
JP2014015451A (ja) * 2012-06-14 2014-01-30 Rohto Pharmaceut Co Ltd 水性眼科組成物
WO2014050301A1 (ja) * 2012-09-27 2014-04-03 千寿製薬株式会社 水性液剤
JP2014166976A (ja) * 2013-01-31 2014-09-11 Rohto Pharmaceut Co Ltd 点眼剤
JP2015024964A (ja) * 2013-07-24 2015-02-05 学校法人近畿大学 Ｃｙｐ２ａ１３阻害剤
JP2017119669A (ja) * 2015-10-15 2017-07-06 ロート製薬株式会社 異物感改善用眼科組成物
WO2018009717A1 (en) * 2016-07-06 2018-01-11 Algomedix, Inc. Trpa1 antagonists for treatment of dry eye, ocular pain and inflammation
JP2018515538A (ja) * 2015-05-15 2018-06-14 シムライズ アーゲー 液状冷却組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6180115B2 (ja) * 2012-01-05 2017-08-16 花王株式会社 刺激感緩和剤
US20130315843A1 (en) * 2012-05-25 2013-11-28 The Procter & Gamble Company Composition for reduction of trpa1 and trpv1 sensations

Patent Citations (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505909A (en) * 1980-09-17 1985-03-19 Bernstein Joel E Method and composition for treating and preventing irritation of the eyes
JPH07316060A (ja) * 1994-03-31 1995-12-05 Lion Corp 安定な点眼剤
JPH09132526A (ja) * 1995-11-09 1997-05-20 Lion Corp 点眼剤
JPH09169642A (ja) * 1995-12-18 1997-06-30 Lion Corp テトラヒドロゾリン含有液剤
JPH09309835A (ja) * 1996-05-21 1997-12-02 Lion Corp グリチルリチン酸アルキルエステル含有薬液
JP2000327573A (ja) * 1999-05-18 2000-11-28 Taisho Pharmaceut Co Ltd 粘膜適用組成物
JP2001302518A (ja) * 2000-02-15 2001-10-31 Rohto Pharmaceut Co Ltd 官能改善方法および官能改善剤
JP2003073303A (ja) * 2001-09-05 2003-03-12 Senju Pharmaceut Co Ltd 眼局所用液剤の清涼化作用の持続方法
JP2003146908A (ja) * 2001-11-12 2003-05-21 Rohto Pharmaceut Co Ltd 水性組成物
JP2003183157A (ja) * 2001-12-19 2003-07-03 Lion Corp 眼科用組成物
US20050271748A1 (en) * 2002-04-26 2005-12-08 Allergan, Inc. Compositions for treating hyperemia
JP2004143156A (ja) * 2002-10-01 2004-05-20 Taisho Pharmaceut Co Ltd 点眼剤
JP2004175770A (ja) * 2002-11-29 2004-06-24 Rohto Pharmaceut Co Ltd ケトチフェン及びイミダゾリン化合物含有組成物
JP2011074092A (ja) * 2003-04-04 2011-04-14 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2006176501A (ja) * 2004-11-26 2006-07-06 Taisho Pharmaceut Co Ltd 眼科用剤
JP2006312627A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有組成物
JP2006312628A (ja) * 2005-04-08 2006-11-16 Rohto Pharmaceut Co Ltd アシタザノラスト含有水性組成物
WO2007108541A1 (ja) * 2006-03-23 2007-09-27 Senju Pharmaceutical Co., Ltd. キサンタンガムおよびブドウ糖を含有する眼科用組成物
JP2008024700A (ja) * 2006-06-23 2008-02-07 Rohto Pharmaceut Co Ltd ベルベリン含有水性組成物
JP2009096793A (ja) * 2007-06-01 2009-05-07 Rohto Pharmaceut Co Ltd プラノプロフェン含有水性医薬組成物
JP2009029779A (ja) * 2007-06-29 2009-02-12 Rohto Pharmaceut Co Ltd レボカバスチン及び／又はその塩を含有する水性医薬組成物
JP2011093897A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科用液体組成物
JP2011093898A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 眼科組成物
JP2012144509A (ja) * 2011-01-12 2012-08-02 Saga Seiyaku Kk 多成分配合の点眼剤
JP2012206977A (ja) * 2011-03-29 2012-10-25 Rohto Pharmaceutical Co Ltd 眼科用組成物
JP2013189623A (ja) * 2012-01-30 2013-09-26 Symrise Ag 組成物
JP2013237638A (ja) * 2012-05-15 2013-11-28 Lion Corp 眼科組成物
JP2014015451A (ja) * 2012-06-14 2014-01-30 Rohto Pharmaceut Co Ltd 水性眼科組成物
WO2014050301A1 (ja) * 2012-09-27 2014-04-03 千寿製薬株式会社 水性液剤
JP2014166976A (ja) * 2013-01-31 2014-09-11 Rohto Pharmaceut Co Ltd 点眼剤
JP2015024964A (ja) * 2013-07-24 2015-02-05 学校法人近畿大学 Ｃｙｐ２ａ１３阻害剤
JP2018515538A (ja) * 2015-05-15 2018-06-14 シムライズ アーゲー 液状冷却組成物
JP2017119669A (ja) * 2015-10-15 2017-07-06 ロート製薬株式会社 異物感改善用眼科組成物
WO2018009717A1 (en) * 2016-07-06 2018-01-11 Algomedix, Inc. Trpa1 antagonists for treatment of dry eye, ocular pain and inflammation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PRETI, D. ET AL.: "Transient receptor potential ankyrin 1 (TRPA1) antagonists", PHARMACEUTICAL PATENT ANALYST, vol. 4, no. 2, JPN6020017404, 2015, pages 75 - 94, ISSN: 0005269854 *

Also Published As

Publication number Publication date
CN113423428A (zh) 2021-09-21
TW202100144A (zh) 2021-01-01
WO2020184479A1 (ja) 2020-09-17
JP2024180505A (ja) 2024-12-26

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